Compile Data Set for Download or QSAR

Found 56 hits with Last Name = 'cuesta' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50133999 (CHEMBL345035 | N,N'-(9-(2-aminophenylamino)acridin...) Show SMILES Nc1ccccc1Nc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C33H39N7O2/c34-27-7-1-2-8-30(27)38-33-25-21-23(35-31(41)13-19-39-15-3-4-16-39)9-11-28(25)37-29-12-10-24(22-26(29)33)36-32(42)14-20-40-17-5-6-18-40/h1-2,7-12,21-22H,3-6,13-20,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50180773 (3,6-bis[6-(pyrrolidin-1-yl)hexanamido]-9-{4'-[3''-...) Show SMILES O=C(CCCCCN1CCCC1)Nc1ccc2c(Nc3ccc(NC(=O)CCN4CCCC4)cc3)c3ccc(NC(=O)CCCCCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C46H62N8O3/c55-43(13-3-1-5-24-52-26-7-8-27-52)48-37-19-21-39-41(33-37)51-42-34-38(49-44(56)14-4-2-6-25-53-28-9-10-29-53)20-22-40(42)46(39)50-36-17-15-35(16-18-36)47-45(57)23-32-54-30-11-12-31-54/h15-22,33-34H,1-14,23-32H2,(H,47,57)(H,48,55)(H,49,56)(H,50,51)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	146	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134004 (CHEMBL140354 | N,N'-(9-(phenylamino)acridine-2,6-d...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(Nc3ccccc3)c3cc(NC(=O)CCN4CCCC4)ccc3nc2c1 Show InChI InChI=1S/C33H38N6O2/c40-31(14-20-38-16-4-5-17-38)34-25-11-13-29-28(22-25)33(36-24-8-2-1-3-9-24)27-12-10-26(23-30(27)37-29)35-32(41)15-21-39-18-6-7-19-39/h1-3,8-13,22-23H,4-7,14-21H2,(H,34,40)(H,35,41)(H,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134010 (CHEMBL139511 | N,N'-(9-(2-aminophenylamino)acridin...) Show SMILES Nc1ccccc1Nc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C33H39N7O2/c34-27-7-1-2-8-28(27)38-33-25-11-9-23(35-31(41)13-19-39-15-3-4-16-39)21-29(25)37-30-22-24(10-12-26(30)33)36-32(42)14-20-40-17-5-6-18-40/h1-2,7-12,21-22H,3-6,13-20,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134007 (CHEMBL337123 | N-[9-Heptylamino-6-(3-pyrrolidin-1-...) Show SMILES CCCCCCCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C34H48N6O2/c1-2-3-4-5-6-17-35-34-28-13-11-26(36-32(41)15-22-39-18-7-8-19-39)24-30(28)38-31-25-27(12-14-29(31)34)37-33(42)16-23-40-20-9-10-21-40/h11-14,24-25H,2-10,15-23H2,1H3,(H,35,38)(H,36,41)(H,37,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134009 (CHEMBL335132 | N,N'-(9-(3-(dimethylamino)propylami...) Show SMILES CN(C)CCCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C32H45N7O2/c1-37(2)15-7-14-33-32-26-10-8-24(34-30(40)12-20-38-16-3-4-17-38)22-28(26)36-29-23-25(9-11-27(29)32)35-31(41)13-21-39-18-5-6-19-39/h8-11,22-23H,3-7,12-21H2,1-2H3,(H,33,36)(H,34,40)(H,35,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134011 (CHEMBL343609 | N,N'-(9-(2-aminophenylamino)acridin...) Show SMILES Nc1ccccc1Nc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C33H39N7O2/c34-27-7-1-2-8-29(27)38-33-25-11-9-24(36-32(42)14-20-40-17-5-6-18-40)22-30(25)37-28-12-10-23(21-26(28)33)35-31(41)13-19-39-15-3-4-16-39/h1-2,7-12,21-22H,3-6,13-20,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134012 (CHEMBL342480 | N,N'-(9-(3-aminophenylamino)acridin...) Show SMILES Nc1cccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3ccc(NC(=O)CCN4CCCC4)cc23)c1 Show InChI InChI=1S/C33H39N7O2/c34-23-6-5-7-24(20-23)37-33-27-10-8-26(36-32(42)13-19-40-16-3-4-17-40)22-30(27)38-29-11-9-25(21-28(29)33)35-31(41)12-18-39-14-1-2-15-39/h5-11,20-22H,1-4,12-19,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134014 (CHEMBL343041 | N,N'-(9-(2-hydroxyphenylamino)acrid...) Show SMILES Oc1ccccc1Nc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C33H38N6O3/c40-30-8-2-1-7-29(30)37-33-25-21-23(34-31(41)13-19-38-15-3-4-16-38)9-11-27(25)36-28-12-10-24(22-26(28)33)35-32(42)14-20-39-17-5-6-18-39/h1-2,7-12,21-22,40H,3-6,13-20H2,(H,34,41)(H,35,42)(H,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134018 (CHEMBL335819 | N,N'-(9-(4-aminophenylamino)acridin...) Show SMILES Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C33H39N7O2/c34-23-5-7-24(8-6-23)37-33-27-11-9-25(35-31(41)13-19-39-15-1-2-16-39)21-29(27)38-30-22-26(10-12-28(30)33)36-32(42)14-20-40-17-3-4-18-40/h5-12,21-22H,1-4,13-20,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50133998 (CHEMBL137809 | N,N'-(9-(2-(methylthio)phenylamino)...) Show SMILES CSc1ccccc1Nc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C34H40N6O2S/c1-43-31-9-3-2-8-28(31)38-34-26-12-10-24(35-32(41)14-20-39-16-4-5-17-39)22-29(26)37-30-23-25(11-13-27(30)34)36-33(42)15-21-40-18-6-7-19-40/h2-3,8-13,22-23H,4-7,14-21H2,1H3,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134024 (CHEMBL139500 | N,N'-(9-(3-aminophenylamino)acridin...) Show SMILES Nc1cccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)c1 Show InChI InChI=1S/C33H39N7O2/c34-23-6-5-7-24(20-23)37-33-27-21-25(35-31(41)12-18-39-14-1-2-15-39)8-10-29(27)38-30-11-9-26(22-28(30)33)36-32(42)13-19-40-16-3-4-17-40/h5-11,20-22H,1-4,12-19,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50080849 (3,6-Bis(3-pyrrolidinopropionamido)acridine | 3-PYR...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2cc3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C27H33N5O2/c33-26(9-15-31-11-1-2-12-31)28-22-7-5-20-17-21-6-8-23(19-25(21)30-24(20)18-22)29-27(34)10-16-32-13-3-4-14-32/h5-8,17-19H,1-4,9-16H2,(H,28,33)(H,29,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134025 (CHEMBL343795 | N,N'-(9-(4-fluorophenylamino)acridi...) Show SMILES Fc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C33H37FN6O2/c34-23-5-7-24(8-6-23)37-33-27-11-9-25(35-31(41)13-19-39-15-1-2-16-39)21-29(27)38-30-22-26(10-12-28(30)33)36-32(42)14-20-40-17-3-4-18-40/h5-12,21-22H,1-4,13-20H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134021 (CHEMBL138761 | N,N'-(9-(3-(methylthio)phenylamino)...) Show SMILES CSc1cccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)c1 Show InChI InChI=1S/C34H40N6O2S/c1-43-27-8-6-7-24(21-27)37-34-28-11-9-25(35-32(41)13-19-39-15-2-3-16-39)22-30(28)38-31-23-26(10-12-29(31)34)36-33(42)14-20-40-17-4-5-18-40/h6-12,21-23H,2-5,13-20H2,1H3,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134029 (CHEMBL138369 | N,N'-(9-(phenylamino)acridine-2,7-d...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2nc3ccc(NC(=O)CCN4CCCC4)cc3c(Nc3ccccc3)c2c1 Show InChI InChI=1S/C33H38N6O2/c40-31(14-20-38-16-4-5-17-38)34-25-10-12-29-27(22-25)33(36-24-8-2-1-3-9-24)28-23-26(11-13-30(28)37-29)35-32(41)15-21-39-18-6-7-19-39/h1-3,8-13,22-23H,4-7,14-21H2,(H,34,40)(H,35,41)(H,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134016 (CHEMBL342921 | N,N'-(9-(3-methoxyphenylamino)acrid...) Show SMILES COc1cccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)c1 Show InChI InChI=1S/C34H40N6O3/c1-43-27-8-6-7-24(21-27)37-34-28-22-25(35-32(41)13-19-39-15-2-3-16-39)9-11-30(28)38-31-12-10-26(23-29(31)34)36-33(42)14-20-40-17-4-5-18-40/h6-12,21-23H,2-5,13-20H2,1H3,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134002 (CHEMBL141540 | N,N'-(9-(2-(piperidin-1-yl)ethylami...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(NCCN3CCCCC3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C34H47N7O2/c42-32(12-21-39-17-4-5-18-39)36-26-8-10-28-30(24-26)38-31-25-27(37-33(43)13-22-40-19-6-7-20-40)9-11-29(31)34(28)35-14-23-41-15-2-1-3-16-41/h8-11,24-25H,1-7,12-23H2,(H,35,38)(H,36,42)(H,37,43)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134028 (CHEMBL142036 | N,N'-(9-(4-aminophenylamino)acridin...) Show SMILES Nc1ccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 Show InChI InChI=1S/C33H39N7O2/c34-23-5-7-24(8-6-23)37-33-27-21-25(35-31(41)13-19-39-15-1-2-16-39)9-11-29(27)38-30-12-10-26(22-28(30)33)36-32(42)14-20-40-17-3-4-18-40/h5-12,21-22H,1-4,13-20,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134019 (CHEMBL336417 | N,N'-(9-(3-aminophenylamino)acridin...) Show SMILES Nc1cccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)c1 Show InChI InChI=1S/C33H39N7O2/c34-23-6-5-7-24(20-23)37-33-27-10-8-25(35-31(41)12-18-39-14-1-2-15-39)21-29(27)38-30-22-26(9-11-28(30)33)36-32(42)13-19-40-16-3-4-17-40/h5-11,20-22H,1-4,12-19,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134032 (CHEMBL138811 | N,N'-(9-(cyclopropylamino)acridine-...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(NC3CC3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C30H38N6O2/c37-28(11-17-35-13-1-2-14-35)31-22-7-9-24-26(19-22)34-27-20-23(8-10-25(27)30(24)33-21-5-6-21)32-29(38)12-18-36-15-3-4-16-36/h7-10,19-21H,1-6,11-18H2,(H,31,37)(H,32,38)(H,33,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134030 (9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...) Show SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-26(36-33(43)15-21-41-17-3-4-18-41)23-31(29)39-32-24-27(10-14-30(32)35)37-34(44)16-22-42-19-5-6-20-42/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	115	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134031 (CHEMBL137973 | N,N'-(9-(cyclohexylamino)acridine-2...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(NC3CCCCC3)c3cc(NC(=O)CCN4CCCC4)ccc3nc2c1 Show InChI InChI=1S/C33H44N6O2/c40-31(14-20-38-16-4-5-17-38)34-25-11-13-29-28(22-25)33(36-24-8-2-1-3-9-24)27-12-10-26(23-30(27)37-29)35-32(41)15-21-39-18-6-7-19-39/h10-13,22-24H,1-9,14-21H2,(H,34,40)(H,35,41)(H,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134013 (CHEMBL341985 | N,N'-(9-(4-(dimethylamino)phenylami...) Show SMILES CN(C)c1ccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-11-7-25(8-12-28)38-35-29-23-26(36-33(43)15-21-41-17-3-4-18-41)9-13-31(29)39-32-14-10-27(24-30(32)35)37-34(44)16-22-42-19-5-6-20-42/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134022 (CHEMBL336444 | N,N'-(9-(4-acetylphenylamino)acridi...) Show SMILES CC(=O)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C35H40N6O3/c1-24(42)25-6-8-26(9-7-25)38-35-29-12-10-27(36-33(43)14-20-40-16-2-3-17-40)22-31(29)39-32-23-28(11-13-30(32)35)37-34(44)15-21-41-18-4-5-19-41/h6-13,22-23H,2-5,14-21H2,1H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134017 (CHEMBL138357 | N,N'-(9-(4-(dimethylamino)phenylami...) Show SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-27(37-34(44)16-22-42-19-5-6-20-42)24-32(29)39-31-14-10-26(23-30(31)35)36-33(43)15-21-41-17-3-4-18-41/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134026 (CHEMBL138487 | N,N'-(9-(3-(dimethylamino)phenylami...) Show SMILES CN(C)c1cccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)c1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-9-7-8-25(22-28)38-35-29-12-10-26(36-33(43)14-20-41-16-3-4-17-41)23-31(29)39-32-24-27(11-13-30(32)35)37-34(44)15-21-42-18-5-6-19-42/h7-13,22-24H,3-6,14-21H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134033 (CHEMBL139443 | N,N'-(9-(3-(dimethylamino)phenylami...) Show SMILES CN(C)c1cccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)c1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-9-7-8-25(22-28)38-35-29-23-26(36-33(43)14-20-41-16-3-4-17-41)10-12-31(29)39-32-13-11-27(24-30(32)35)37-34(44)15-21-42-18-5-6-19-42/h7-13,22-24H,3-6,14-21H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134015 (CHEMBL44130 | N-[9-[2-(2-Amino-ethyl)-pyrrolidin-1...) Show SMILES NCCC1CCCN1c1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C33H45N7O2/c34-14-11-26-6-5-19-40(26)33-27-9-7-24(35-31(41)12-20-38-15-1-2-16-38)22-29(27)37-30-23-25(8-10-28(30)33)36-32(42)13-21-39-17-3-4-18-39/h7-10,22-23,26H,1-6,11-21,34H2,(H,35,41)(H,36,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134008 (CHEMBL138187 | N,N'-(9-(3-(dimethylamino)propylami...) Show SMILES CN(C)CCCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C32H45N7O2/c1-37(2)15-7-14-33-32-26-10-8-25(35-31(41)13-21-39-18-5-6-19-39)23-29(26)36-28-11-9-24(22-27(28)32)34-30(40)12-20-38-16-3-4-17-38/h8-11,22-23H,3-7,12-21H2,1-2H3,(H,33,36)(H,34,40)(H,35,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134023 (CHEMBL337762 | N,N'-(9-(4-aminophenylamino)acridin...) Show SMILES Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 Show InChI InChI=1S/C33H39N7O2/c34-23-5-7-24(8-6-23)37-33-27-11-9-26(36-32(42)14-20-40-17-3-4-18-40)22-30(27)38-29-12-10-25(21-28(29)33)35-31(41)13-19-39-15-1-2-16-39/h5-12,21-22H,1-4,13-20,34H2,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134006 (CHEMBL335564 | N,N'-(9-(2-methoxyethylamino)acridi...) Show SMILES COCCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C30H40N6O3/c1-39-19-12-31-30-24-8-6-22(32-28(37)10-17-35-13-2-3-14-35)20-26(24)34-27-21-23(7-9-25(27)30)33-29(38)11-18-36-15-4-5-16-36/h6-9,20-21H,2-5,10-19H2,1H3,(H,31,34)(H,32,37)(H,33,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134027 (CHEMBL140180 | N,N'-(9-(2-(dimethylamino)ethylamin...) Show SMILES CN(C)CCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12 Show InChI InChI=1S/C31H43N7O2/c1-36(2)20-13-32-31-25-9-7-23(33-29(39)11-18-37-14-3-4-15-37)21-27(25)35-28-22-24(8-10-26(28)31)34-30(40)12-19-38-16-5-6-17-38/h7-10,21-22H,3-6,11-20H2,1-2H3,(H,32,35)(H,33,39)(H,34,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134020 (CHEMBL141661 | N,N'-(9-(3-acetamidophenylamino)acr...) Show SMILES CC(=O)Nc1cccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)c1 Show InChI InChI=1S/C35H41N7O3/c1-24(43)36-25-7-6-8-26(21-25)39-35-29-11-9-27(37-33(44)13-19-41-15-2-3-16-41)22-31(29)40-32-23-28(10-12-30(32)35)38-34(45)14-20-42-17-4-5-18-42/h6-12,21-23H,2-5,13-20H2,1H3,(H,36,43)(H,37,44)(H,38,45)(H,39,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134003 (CHEMBL141740 | N,N'-(9-(4-methoxyphenylamino)acrid...) Show SMILES COc1ccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 Show InChI InChI=1S/C34H40N6O3/c1-43-27-10-6-24(7-11-27)37-34-28-22-25(35-32(41)14-20-39-16-2-3-17-39)8-12-30(28)38-31-13-9-26(23-29(31)34)36-33(42)15-21-40-18-4-5-19-40/h6-13,22-23H,2-5,14-21H2,1H3,(H,35,41)(H,36,42)(H,37,38)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134005 (CHEMBL137928 | N,N'-(9-(2-(dimethylamino)ethylamin...) Show SMILES CN(C)CCNc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C31H43N7O2/c1-36(2)20-13-32-31-25-21-23(33-29(39)11-18-37-14-3-4-15-37)7-9-27(25)35-28-10-8-24(22-26(28)31)34-30(40)12-19-38-16-5-6-17-38/h7-10,21-22H,3-6,11-20H2,1-2H3,(H,32,35)(H,33,39)(H,34,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134001 (CHEMBL140084 | N,N'-(9-(2-(dimethylamino)ethylamin...) Show SMILES CN(C)CCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C31H43N7O2/c1-36(2)20-13-32-31-25-9-7-24(34-30(40)12-19-38-16-5-6-17-38)22-28(25)35-27-10-8-23(21-26(27)31)33-29(39)11-18-37-14-3-4-15-37/h7-10,21-22H,3-6,11-20H2,1-2H3,(H,32,35)(H,33,39)(H,34,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134034 (CHEMBL139687 | N-[9-[(Pyridin-3-ylmethyl)-amino]-6...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(NCc3cccnc3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C33H39N7O2/c41-31(11-18-39-14-1-2-15-39)36-25-7-9-27-29(20-25)38-30-21-26(37-32(42)12-19-40-16-3-4-17-40)8-10-28(30)33(27)35-23-24-6-5-13-34-22-24/h5-10,13,20-22H,1-4,11-12,14-19,23H2,(H,35,38)(H,36,41)(H,37,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50150618 (CHEMBL182871 | Hexanedioic acid {4-[3,6-bis-(3-pyr...) Show SMILES CCN(CC)CCCCCCNC(=O)CCCCC(=O)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C49H69N9O4/c1-3-56(4-2)28-10-6-5-9-27-50-45(59)15-7-8-16-46(60)51-37-17-19-38(20-18-37)54-49-41-23-21-39(52-47(61)25-33-57-29-11-12-30-57)35-43(41)55-44-36-40(22-24-42(44)49)53-48(62)26-34-58-31-13-14-32-58/h17-24,35-36H,3-16,25-34H2,1-2H3,(H,50,59)(H,51,60)(H,52,61)(H,53,62)(H,54,55)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
University of London School of Pharmacy Curated by ChEMBL					Assay Description Effective concentration against telomerase by TRAP				Bioorg Med Chem Lett 14: 4347-51 (2004) Article DOI: 10.1016/j.bmcl.2004.05.090 BindingDB Entry DOI: 10.7270/Q2KD1XDZ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50150619 (6-Morpholin-4-yl-6-oxo-hexanoic acid {4-[3,6-bis-(...) Show SMILES O=C(CCCCC(=O)N1CCOCC1)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C43H54N8O5/c52-39(7-1-2-8-42(55)51-25-27-56-28-26-51)44-31-9-11-32(12-10-31)47-43-35-15-13-33(45-40(53)17-23-49-19-3-4-20-49)29-37(35)48-38-30-34(14-16-36(38)43)46-41(54)18-24-50-21-5-6-22-50/h9-16,29-30H,1-8,17-28H2,(H,44,52)(H,45,53)(H,46,54)(H,47,48)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	267	n/a	n/a	n/a	n/a
University of London School of Pharmacy Curated by ChEMBL					Assay Description Effective concentration against telomerase by TRAP				Bioorg Med Chem Lett 14: 4347-51 (2004) Article DOI: 10.1016/j.bmcl.2004.05.090 BindingDB Entry DOI: 10.7270/Q2KD1XDZ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50150620 (6-(4-Methyl-piperazin-1-yl)-6-oxo-hexanoic acid {4...) Show SMILES CN1CCN(CC1)C(=O)CCCCC(=O)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C44H57N9O4/c1-50-26-28-53(29-27-50)43(57)9-3-2-8-40(54)45-32-10-12-33(13-11-32)48-44-36-16-14-34(46-41(55)18-24-51-20-4-5-21-51)30-38(36)49-39-31-35(15-17-37(39)44)47-42(56)19-25-52-22-6-7-23-52/h10-17,30-31H,2-9,18-29H2,1H3,(H,45,54)(H,46,55)(H,47,56)(H,48,49)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	165	n/a	n/a	n/a	n/a
University of London School of Pharmacy Curated by ChEMBL					Assay Description Effective concentration against telomerase by TRAP				Bioorg Med Chem Lett 14: 4347-51 (2004) Article DOI: 10.1016/j.bmcl.2004.05.090 BindingDB Entry DOI: 10.7270/Q2KD1XDZ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134030 (9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...) Show SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-26(36-33(43)15-21-41-17-3-4-18-41)23-31(29)39-32-24-27(10-14-30(32)35)37-34(44)16-22-42-19-5-6-20-42/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a
University of London School of Pharmacy Curated by ChEMBL					Assay Description Effective concentration against telomerase by TRAP				Bioorg Med Chem Lett 14: 4347-51 (2004) Article DOI: 10.1016/j.bmcl.2004.05.090 BindingDB Entry DOI: 10.7270/Q2KD1XDZ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50150621 (6-Oxo-6-pyrrolidin-1-yl-hexanoic acid {4-[3,6-bis-...) Show SMILES O=C(CCCCC(=O)N1CCCC1)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C43H54N8O4/c52-39(9-1-2-10-42(55)51-25-7-8-26-51)44-31-11-13-32(14-12-31)47-43-35-17-15-33(45-40(53)19-27-49-21-3-4-22-49)29-37(35)48-38-30-34(16-18-36(38)43)46-41(54)20-28-50-23-5-6-24-50/h11-18,29-30H,1-10,19-28H2,(H,44,52)(H,45,53)(H,46,54)(H,47,48)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	318	n/a	n/a	n/a	n/a
University of London School of Pharmacy Curated by ChEMBL					Assay Description Effective concentration against telomerase by TRAP				Bioorg Med Chem Lett 14: 4347-51 (2004) Article DOI: 10.1016/j.bmcl.2004.05.090 BindingDB Entry DOI: 10.7270/Q2KD1XDZ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50150622 (CHEMBL184587 | Hexanedioic acid {4-[3,6-bis-(3-pyr...) Show SMILES CCN(CC)CCNC(=O)CCCCC(=O)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C45H61N9O4/c1-3-52(4-2)30-23-46-41(55)11-5-6-12-42(56)47-33-13-15-34(16-14-33)50-45-37-19-17-35(48-43(57)21-28-53-24-7-8-25-53)31-39(37)51-40-32-36(18-20-38(40)45)49-44(58)22-29-54-26-9-10-27-54/h13-20,31-32H,3-12,21-30H2,1-2H3,(H,46,55)(H,47,56)(H,48,57)(H,49,58)(H,50,51)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
University of London School of Pharmacy Curated by ChEMBL					Assay Description Effective concentration against telomerase by TRAP				Bioorg Med Chem Lett 14: 4347-51 (2004) Article DOI: 10.1016/j.bmcl.2004.05.090 BindingDB Entry DOI: 10.7270/Q2KD1XDZ
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50180764 (2-pyrrolidin-1-yl-N-[6-(2-pyrrolidin-1-yl-acetylam...) Show SMILES O=C(CN1CCCC1)Nc1ccc2cc3ccc(NC(=O)CN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C25H29N5O2/c31-24(16-29-9-1-2-10-29)26-20-7-5-18-13-19-6-8-21(15-23(19)28-22(18)14-20)27-25(32)17-30-11-3-4-12-30/h5-8,13-15H,1-4,9-12,16-17H2,(H,26,31)(H,27,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50180765 (CHEMBL381966 | N-[4-(acridin-9-ylamino)-phenyl]-3-...) Show SMILES O=C(CCN1CCCC1)Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 Show InChI InChI=1S/C26H26N4O/c31-25(15-18-30-16-5-6-17-30)27-19-11-13-20(14-12-19)28-26-21-7-1-3-9-23(21)29-24-10-4-2-8-22(24)26/h1-4,7-14H,5-6,15-18H2,(H,27,31)(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50180767 (3,6-bis[3-(pyrrolidin-1-yl)propionamido]-9-{4'-[2'...) Show SMILES O=C(CCN1CCCC1)Nc1ccc2c(Nc3ccc(NC(=O)CN4CCCC4)cc3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C39H48N8O3/c48-36(15-23-45-17-1-2-18-45)41-30-11-13-32-34(25-30)44-35-26-31(42-37(49)16-24-46-19-3-4-20-46)12-14-33(35)39(32)43-29-9-7-28(8-10-29)40-38(50)27-47-21-5-6-22-47/h7-14,25-26H,1-6,15-24,27H2,(H,40,50)(H,41,48)(H,42,49)(H,43,44)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	167	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134030 (9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyr...) Show SMILES CN(C)c1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C35H43N7O2/c1-40(2)28-11-7-25(8-12-28)38-35-29-13-9-26(36-33(43)15-21-41-17-3-4-18-41)23-31(29)39-32-24-27(10-14-30(32)35)37-34(44)16-22-42-19-5-6-20-42/h7-14,23-24H,3-6,15-22H2,1-2H3,(H,36,43)(H,37,44)(H,38,39)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50180770 (3,6-bis[3-(pyrrolidin-1-yl)propionamido]-9-{4'-[3'...) Show SMILES O=C(CCN1CCCC1)Nc1ccc(Nc2c3ccc(NC(=O)CCN4CCCC4)cc3nc3cc(NC(=O)CCN4CCCC4)ccc23)cc1 Show InChI InChI=1S/C40H50N8O3/c49-37(15-24-46-18-1-2-19-46)41-29-7-9-30(10-8-29)44-40-33-13-11-31(42-38(50)16-25-47-20-3-4-21-47)27-35(33)45-36-28-32(12-14-34(36)40)43-39(51)17-26-48-22-5-6-23-48/h7-14,27-28H,1-6,15-26H2,(H,41,49)(H,42,50)(H,43,51)(H,44,45)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50180763 (3,6-bis[5-(pyrrolidin-1-yl)pentanamido]-9-{4'-[3''...) Show SMILES O=C(CCCCN1CCCC1)Nc1ccc2c(Nc3ccc(NC(=O)CCN4CCCC4)cc3)c3ccc(NC(=O)CCCCN4CCCC4)cc3nc2c1 Show InChI InChI=1S/C44H58N8O3/c53-41(11-1-3-22-50-24-5-6-25-50)46-35-17-19-37-39(31-35)49-40-32-36(47-42(54)12-2-4-23-51-26-7-8-27-51)18-20-38(40)44(37)48-34-15-13-33(14-16-34)45-43(55)21-30-52-28-9-10-29-52/h13-20,31-32H,1-12,21-30H2,(H,45,55)(H,46,53)(H,47,54)(H,48,49)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	255	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibition of telomerase activity from human A2780 cells				J Med Chem 49: 582-99 (2006) Article DOI: 10.1021/jm050555a BindingDB Entry DOI: 10.7270/Q2CN73GR
					More data for this Ligand-Target Pair

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