BindingDB PrimarySearch

Found 226 hits with Last Name = 'meiler' and Initial = 'j'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Effect on neuropeptide Y-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Effect on peptide YY-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell mem...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50042441 (CHEMBL3353290) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50445222 (CHEMBL3105228) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	661	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50534551 (CHEMBL4448840) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50563421 (CHEMBL4745232) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02000 BindingDB Entry DOI: 10.7270/Q24F1VGB
TBA					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50563421 (CHEMBL4745232) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02000 BindingDB Entry DOI: 10.7270/Q24F1VGB
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50534551 (CHEMBL4448840) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Mus musculus (Mouse))	BDBM50563421 (CHEMBL4745232) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02000 BindingDB Entry DOI: 10.7270/Q24F1VGB
TBA					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Mus musculus (Mouse))	BDBM50563421 (CHEMBL4745232) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02000 BindingDB Entry DOI: 10.7270/Q24F1VGB
TBA					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50563420 (CHEMBL4780125) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02000 BindingDB Entry DOI: 10.7270/Q24F1VGB
TBA					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50563420 (CHEMBL4780125) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02000 BindingDB Entry DOI: 10.7270/Q24F1VGB
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534551 (CHEMBL4448840) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50441232 (CHEMBL2431173) Show SMILES CC1(COC1)NC(=O)c1ccc(cn1)C#Cc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of human CYP1A2				J Med Chem 56: 7976-96 (2013) Article DOI: 10.1021/jm401028t BindingDB Entry DOI: 10.7270/Q2571DFR
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534554 (CHEMBL4564756) Show SMILES Fc1ccc(cc1F)S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534555 (CHEMBL4464533) Show SMILES Fc1ccc(cc1Cl)S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534556 (CHEMBL4441929) Show SMILES Cn1cc(cn1)S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534557 (CHEMBL4518312) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CCCO2)CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534558 (CHEMBL4461436) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCO2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534553 (CHEMBL4565823) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534552 (CHEMBL4445022) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M4 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534548 (CHEMBL4434942) Show SMILES Cc1noc(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50534551 (CHEMBL4448840) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M4 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534560 (CHEMBL4441660) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534549 (CHEMBL4520791) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)SCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50534550 (CHEMBL4542697) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50534559 (CHEMBL4464794) Show SMILES Cc1c(cnn1C)S(=O)(=O)N1CCC2(CC1)OCCS2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50441232 (CHEMBL2431173) Show SMILES CC1(COC1)NC(=O)c1ccc(cn1)C#Cc1cccc(F)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of human CYP2C9				J Med Chem 56: 7976-96 (2013) Article DOI: 10.1021/jm401028t BindingDB Entry DOI: 10.7270/Q2571DFR
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50042441 (CHEMBL3353290) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50441232 (CHEMBL2431173) Show SMILES CC1(COC1)NC(=O)c1ccc(cn1)C#Cc1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of human CYP2D6				J Med Chem 56: 7976-96 (2013) Article DOI: 10.1021/jm401028t BindingDB Entry DOI: 10.7270/Q2571DFR
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50445222 (CHEMBL3105228) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50042441 (CHEMBL3353290) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M2 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50445222 (CHEMBL3105228) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50445222 (CHEMBL3105228) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50445222 (CHEMBL3105228) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M4 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50042441 (CHEMBL3353290) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M3 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50042441 (CHEMBL3353290) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M4 receptor assessed as inhibition of acetylcholine-induced calcium response				Bioorg Med Chem Lett 26: 4487-4491 (2016) Article DOI: 10.1016/j.bmcl.2016.07.071 BindingDB Entry DOI: 10.7270/Q2MG7T0M
Vanderbilt University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 2 (Homo sapiens (Human))	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 1 (Homo sapiens (Human))	BDBM86143 (L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 2 (Homo sapiens (Human))	BDBM50336912 (Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	379	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 2 (Homo sapiens (Human))	BDBM50060728 ((R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-hyd...) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	233	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 2 (Homo sapiens (Human))	BDBM50394975 (CHEMBL2165921) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair
Neuropeptide FF receptor 2 (Homo sapiens (Human))	BDBM50394976 (CHEMBL2165922) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	298	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...				J Med Chem 55: 6124-36 (2012) Article DOI: 10.1021/jm300535s BindingDB Entry DOI: 10.7270/Q26974PV
Leipzig University Curated by ChEMBL					More data for this Ligand-Target Pair

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