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Compile Data Set for Download or QSAR

Found 51 hits with Last Name = 'nihei' and Initial = 'k'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosinase


(Homo sapiens (Human))		BDBM50263336
PNG
(4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol | CHEMBL4...)
Show SMILES Oc1ccc(CCc2ccc(O)cc2O)c(O)c1
Show InChI InChI=1S/C14H14O4/c15-11-5-3-9(13(17)7-11)1-2-10-4-6-12(16)8-14(10)18/h3-8,15-18H,1-2H2
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n/an/a 370n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50263336
PNG
(4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol | CHEMBL4...)
Show SMILES Oc1ccc(CCc2ccc(O)cc2O)c(O)c1
Show InChI InChI=1S/C14H14O4/c15-11-5-3-9(13(17)7-11)1-2-10-4-6-12(16)8-14(10)18/h3-8,15-18H,1-2H2
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n/an/a 370n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase

Bioorg Med Chem Lett 18: 5252-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.053
BindingDB Entry DOI: 10.7270/Q2VX0GBZ
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50503718
PNG
(CHEMBL4439507)
Show SMILES OC[C@H]1O[C@@H](OCCCCCCCCCCCCCCc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C26H44O8/c27-18-22-23(30)24(31)25(32)26(34-22)33-16-12-10-8-6-4-2-1-3-5-7-9-11-13-19-14-15-20(28)17-21(19)29/h14-15,17,22-32H,1-13,16,18H2/t22-,23-,24+,25-,26-/m1/s1
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n/an/a 390n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50503713
PNG
(CHEMBL4462064)
Show SMILES OC[C@H]1O[C@@H](OCCCCCCCCCCc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C22H36O8/c23-14-18-19(26)20(27)21(28)22(30-18)29-12-8-6-4-2-1-3-5-7-9-15-10-11-16(24)13-17(15)25/h10-11,13,18-28H,1-9,12,14H2/t18-,19-,20+,21-,22-/m1/s1
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n/an/a 410n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50264086
PNG
((2S,3R,4S,5R)-2-(4-(2,4-dihydroxyphenethyl)-3-hydr...)
Show SMILES O[C@@H]1CO[C@@H](Oc2ccc(CCc3ccc(O)cc3O)c(O)c2)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H22O8/c20-12-5-3-10(14(21)7-12)1-2-11-4-6-13(8-15(11)22)27-19-18(25)17(24)16(23)9-26-19/h3-8,16-25H,1-2,9H2/t16-,17+,18-,19+/m1/s1
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n/an/a 430n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase

Bioorg Med Chem Lett 18: 5252-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.053
BindingDB Entry DOI: 10.7270/Q2VX0GBZ
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50264086
PNG
((2S,3R,4S,5R)-2-(4-(2,4-dihydroxyphenethyl)-3-hydr...)
Show SMILES O[C@@H]1CO[C@@H](Oc2ccc(CCc3ccc(O)cc3O)c(O)c2)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H22O8/c20-12-5-3-10(14(21)7-12)1-2-11-4-6-13(8-15(11)22)27-19-18(25)17(24)16(23)9-26-19/h3-8,16-25H,1-2,9H2/t16-,17+,18-,19+/m1/s1
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n/an/a 430n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50292636
PNG
(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Show SMILES CCCCCCc1ccc(O)cc1O
Show InChI InChI=1S/C12H18O2/c1-2-3-4-5-6-10-7-8-11(13)9-12(10)14/h7-9,13-14H,2-6H2,1H3
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n/an/a 560n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50292636
PNG
(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Show SMILES CCCCCCc1ccc(O)cc1O
Show InChI InChI=1S/C12H18O2/c1-2-3-4-5-6-10-7-8-11(13)9-12(10)14/h7-9,13-14H,2-6H2,1H3
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n/an/a 560n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50292636
PNG
(4-hexyl resorcinol | ACRISORCIN | CHEMBL443605)
Show SMILES CCCCCCc1ccc(O)cc1O
Show InChI InChI=1S/C12H18O2/c1-2-3-4-5-6-10-7-8-11(13)9-12(10)14/h7-9,13-14H,2-6H2,1H3
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n/an/a 610n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50503714
PNG
(CHEMBL4456030)
Show SMILES OC[C@H]1O[C@@H](OCCCCCCc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C18H28O8/c19-10-14-15(22)16(23)17(24)18(26-14)25-8-4-2-1-3-5-11-6-7-12(20)9-13(11)21/h6-7,9,14-24H,1-5,8,10H2/t14-,15-,16+,17-,18-/m1/s1
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n/an/a 630n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50340788
PNG
(4-(beta-D-Cellobiopyranosyl)-2,2',4'-trihydroxybib...)
Show SMILES OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](Oc3ccc(CCc4ccc(O)cc4O)c(O)c3)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C26H34O14/c27-9-17-19(32)20(33)22(35)26(38-17)40-24-18(10-28)39-25(23(36)21(24)34)37-14-6-4-12(16(31)8-14)2-1-11-3-5-13(29)7-15(11)30/h3-8,17-36H,1-2,9-10H2/t17-,18-,19-,20+,21-,22-,23-,24-,25-,26+/m1/s1
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n/an/a 680n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50264087
PNG
((2S,2'S,3R,3'R,4S,4'S,5R,5'R)-2,2'-(4-(2,4-dihydro...)
Show SMILES O[C@@H]1CO[C@@H](Oc2ccc(CCc3ccc(O)cc3O)c(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c2)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C24H30O12/c25-13-5-3-11(15(26)7-13)1-2-12-4-6-14(35-23-21(31)19(29)16(27)9-33-23)8-18(12)36-24-22(32)20(30)17(28)10-34-24/h3-8,16-17,19-32H,1-2,9-10H2/t16-,17-,19+,20+,21-,22-,23+,24+/m1/s1
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n/an/a 730n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50264087
PNG
((2S,2'S,3R,3'R,4S,4'S,5R,5'R)-2,2'-(4-(2,4-dihydro...)
Show SMILES O[C@@H]1CO[C@@H](Oc2ccc(CCc3ccc(O)cc3O)c(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c2)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C24H30O12/c25-13-5-3-11(15(26)7-13)1-2-12-4-6-14(35-23-21(31)19(29)16(27)9-33-23)8-18(12)36-24-22(32)20(30)17(28)10-34-24/h3-8,16-17,19-32H,1-2,9-10H2/t16-,17-,19+,20+,21-,22-,23+,24+/m1/s1
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n/an/a 730n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase

Bioorg Med Chem Lett 18: 5252-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.053
BindingDB Entry DOI: 10.7270/Q2VX0GBZ
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50340787
PNG
(4-(beta-D-Glucopyranosyl)-2,2',4'-trihydroxybibenz...)
Show SMILES OC[C@H]1O[C@@H](Oc2ccc(CCc3ccc(O)cc3O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C20H24O9/c21-9-16-17(25)18(26)19(27)20(29-16)28-13-6-4-11(15(24)8-13)2-1-10-3-5-12(22)7-14(10)23/h3-8,16-27H,1-2,9H2/t16-,17-,18+,19-,20-/m1/s1
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n/an/a 770n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50340789
PNG
(2,2',4'-Trihydroxy-4-(beta-D-maltopyranosyl)bibenz...)
Show SMILES OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](Oc3ccc(CCc4ccc(O)cc4O)c(O)c3)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C26H34O14/c27-9-17-19(32)20(33)22(35)26(38-17)40-24-18(10-28)39-25(23(36)21(24)34)37-14-6-4-12(16(31)8-14)2-1-11-3-5-13(29)7-15(11)30/h3-8,17-36H,1-2,9-10H2/t17-,18-,19-,20+,21-,22-,23-,24-,25-,26-/m1/s1
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n/an/a 830n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50503717
PNG
(CHEMBL4465094)
Show SMILES OC[C@H]1O[C@@H](OCCCCc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C16H24O8/c17-8-12-13(20)14(21)15(22)16(24-12)23-6-2-1-3-9-4-5-10(18)7-11(9)19/h4-5,7,12-22H,1-3,6,8H2/t12-,13-,14+,15-,16-/m1/s1
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n/an/a 1.36E+3n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50120802
PNG
(CHEMBL3100130)
Show SMILES [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C22H34O13/c1-9(2-3-10-4-5-11(25)6-12(10)26)32-21-19(31)17(29)20(14(8-24)34-21)35-22-18(30)16(28)15(27)13(7-23)33-22/h4-6,9,13-31H,2-3,7-8H2,1H3/t9-,13-,14-,15-,16+,17-,18-,19-,20-,21-,22+/m1/s1
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n/an/a 1.51E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120802
PNG
(CHEMBL3100130)
Show SMILES [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C22H34O13/c1-9(2-3-10-4-5-11(25)6-12(10)26)32-21-19(31)17(29)20(14(8-24)34-21)35-22-18(30)16(28)15(27)13(7-23)33-22/h4-6,9,13-31H,2-3,7-8H2,1H3/t9-,13-,14-,15-,16+,17-,18-,19-,20-,21-,22+/m1/s1
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n/an/a 1.51E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50264085
PNG
((2S,3R,4S,5R)-2-(2-(2,4-dihydroxyphenethyl)-5-hydr...)
Show SMILES O[C@@H]1CO[C@@H](Oc2cc(O)ccc2CCc2ccc(O)cc2O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H22O8/c20-12-5-3-10(14(22)7-12)1-2-11-4-6-13(21)8-16(11)27-19-18(25)17(24)15(23)9-26-19/h3-8,15,17-25H,1-2,9H2/t15-,17+,18-,19+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50264085
PNG
((2S,3R,4S,5R)-2-(2-(2,4-dihydroxyphenethyl)-5-hydr...)
Show SMILES O[C@@H]1CO[C@@H](Oc2cc(O)ccc2CCc2ccc(O)cc2O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H22O8/c20-12-5-3-10(14(22)7-12)1-2-11-4-6-13(21)8-16(11)27-19-18(25)17(24)15(23)9-26-19/h3-8,15,17-25H,1-2,9H2/t15-,17+,18-,19+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase

Bioorg Med Chem Lett 18: 5252-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.053
BindingDB Entry DOI: 10.7270/Q2VX0GBZ
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50120803
PNG
(CHEMBL3100134)
Show SMILES [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)OC[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H22O7/c1-8(2-3-9-4-5-10(16)6-11(9)17)22-15-14(20)13(19)12(18)7-21-15/h4-6,8,12-20H,2-3,7H2,1H3/t8-,12-,13+,14-,15+/m1/s1
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n/an/a 1.72E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120803
PNG
(CHEMBL3100134)
Show SMILES [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)OC[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H22O7/c1-8(2-3-9-4-5-10(16)6-11(9)17)22-15-14(20)13(19)12(18)7-21-15/h4-6,8,12-20H,2-3,7H2,1H3/t8-,12-,13+,14-,15+/m1/s1
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n/an/a 1.72E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120804
PNG
(CHEMBL3618459)
Show SMILES C[C@@H](O)CCc1ccc(O)cc1O |r|
Show InChI InChI=1S/C10H14O3/c1-7(11)2-3-8-4-5-9(12)6-10(8)13/h4-7,11-13H,2-3H2,1H3/t7-/m1/s1
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n/an/a 1.78E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120800
PNG
(CHEMBL3618460)
Show SMILES [H][C@]1(O[C@@H]2[C@@H](CO)O[C@@H](O[C@H](C)CCc3ccc(O)cc3O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C22H34O13/c1-9(2-3-10-4-5-11(25)6-12(10)26)32-21-19(31)17(29)20(14(8-24)34-21)35-22-18(30)16(28)15(27)13(7-23)33-22/h4-6,9,13-31H,2-3,7-8H2,1H3/t9-,13-,14-,15-,16+,17-,18-,19-,20-,21-,22-/m1/s1
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n/an/a 1.98E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120813
PNG
(CHEMBL3618457)
Show SMILES C[C@H](O)CCc1ccc(O)cc1O |r|
Show InChI InChI=1S/C10H14O3/c1-7(11)2-3-8-4-5-9(12)6-10(8)13/h4-7,11-13H,2-3H2,1H3/t7-/m0/s1
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n/an/a 2.17E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120806
PNG
(CHEMBL3100132)
Show SMILES [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C16H24O8/c1-8(2-3-9-4-5-10(18)6-11(9)19)23-16-15(22)14(21)13(20)12(7-17)24-16/h4-6,8,12-22H,2-3,7H2,1H3/t8-,12-,13-,14+,15-,16-/m1/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50139369
PNG
(2-Hydroxy-4-isopropyl-benzaldehyde | CHEMBL353354)
Show SMILES CC(C)c1ccc(C=O)c(O)c1
Show InChI InChI=1S/C10H12O2/c1-7(2)8-3-4-9(6-11)10(12)5-8/h3-7,12H,1-2H3
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n/an/a 2.30E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase

Bioorg Med Chem Lett 14: 681-3 (2004)


BindingDB Entry DOI: 10.7270/Q27S7N6X
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50120806
PNG
(CHEMBL3100132)
Show SMILES [H][C@@]1(O[C@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C16H24O8/c1-8(2-3-9-4-5-10(18)6-11(9)19)23-16-15(22)14(21)13(20)12(7-17)24-16/h4-6,8,12-22H,2-3,7H2,1H3/t8-,12-,13-,14+,15-,16-/m1/s1
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n/an/a 2.30E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50503712
PNG
(CHEMBL4541503)
Show SMILES OC[C@H]1O[C@@H](OCCCc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H22O8/c16-7-11-12(19)13(20)14(21)15(23-11)22-5-1-2-8-3-4-9(17)6-10(8)18/h3-4,6,11-21H,1-2,5,7H2/t11-,12-,13+,14-,15-/m1/s1
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n/an/a 3.62E+3n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120810
PNG
(CHEMBL3100135)
Show SMILES [H][C@@]1(O[C@@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C22H34O13/c1-9(2-3-10-4-5-11(25)6-12(10)26)32-21-19(31)17(29)20(14(8-24)34-21)35-22-18(30)16(28)15(27)13(7-23)33-22/h4-6,9,13-31H,2-3,7-8H2,1H3/t9-,13+,14+,15+,16-,17+,18+,19+,20+,21+,22-/m0/s1
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n/an/a 3.83E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50120810
PNG
(CHEMBL3100135)
Show SMILES [H][C@@]1(O[C@@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C22H34O13/c1-9(2-3-10-4-5-11(25)6-12(10)26)32-21-19(31)17(29)20(14(8-24)34-21)35-22-18(30)16(28)15(27)13(7-23)33-22/h4-6,9,13-31H,2-3,7-8H2,1H3/t9-,13+,14+,15+,16-,17+,18+,19+,20+,21+,22-/m0/s1
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n/an/a 3.83E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120807
PNG
(CHEMBL3618458)
Show SMILES [H][C@]1(O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H](C)CCc3ccc(O)cc3O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C22H34O13/c1-9(2-3-10-4-5-11(25)6-12(10)26)32-21-19(31)17(29)20(14(8-24)34-21)35-22-18(30)16(28)15(27)13(7-23)33-22/h4-6,9,13-31H,2-3,7-8H2,1H3/t9-,13+,14+,15+,16-,17+,18+,19+,20+,21+,22+/m0/s1
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n/an/a 4.13E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50120811
PNG
(CHEMBL3100133)
Show SMILES [H][C@@]1(O[C@@H](C)CCc2ccc(O)cc2O)OC[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H22O7/c1-8(2-3-9-4-5-10(16)6-11(9)17)22-15-14(20)13(19)12(18)7-21-15/h4-6,8,12-20H,2-3,7H2,1H3/t8-,12+,13-,14+,15-/m0/s1
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n/an/a 4.56E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120811
PNG
(CHEMBL3100133)
Show SMILES [H][C@@]1(O[C@@H](C)CCc2ccc(O)cc2O)OC[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H22O7/c1-8(2-3-9-4-5-10(16)6-11(9)17)22-15-14(20)13(19)12(18)7-21-15/h4-6,8,12-20H,2-3,7H2,1H3/t8-,12+,13-,14+,15-/m0/s1
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n/an/a 4.56E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50120814
PNG
(CHEMBL3100131)
Show SMILES [H][C@@]1(O[C@@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C16H24O8/c1-8(2-3-9-4-5-10(18)6-11(9)19)23-16-15(22)14(21)13(20)12(7-17)24-16/h4-6,8,12-22H,2-3,7H2,1H3/t8-,12+,13+,14-,15+,16+/m0/s1
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n/an/a 4.72E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50120814
PNG
(CHEMBL3100131)
Show SMILES [H][C@@]1(O[C@@H](C)CCc2ccc(O)cc2O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C16H24O8/c1-8(2-3-9-4-5-10(18)6-11(9)19)23-16-15(22)14(21)13(20)12(7-17)24-16/h4-6,8,12-22H,2-3,7H2,1H3/t8-,12+,13+,14-,15+,16+/m0/s1
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n/an/a 4.72E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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n/an/a 7.40E+3n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of Tyrosinase

Eur J Med Chem 46: 1374-81 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.065
BindingDB Entry DOI: 10.7270/Q20V8D41
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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n/an/a 7.40E+3n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase

Bioorg Med Chem Lett 18: 5252-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.053
BindingDB Entry DOI: 10.7270/Q2VX0GBZ
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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n/an/a 9.15E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate assessed as formation of dopachrome by spectrophotometric analysis

Bioorg Med Chem 23: 6650-8 (2015)


Article DOI: 10.1016/j.bmc.2015.09.014
BindingDB Entry DOI: 10.7270/Q2DR2X9W
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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n/an/a 9.15E+3n/an/an/an/an/an/a



Tokyo University of Agriculture and Technology

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-DOPA as substrate assessed as dopachrome formation after 5 mins by spectrophotometry

Bioorg Med Chem Lett 24: 122-5 (2014)


Article DOI: 10.1016/j.bmcl.2013.11.063
BindingDB Entry DOI: 10.7270/Q2NZ8BMD
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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n/an/a 1.07E+4n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50139368
PNG
(2-Hydroxy-4-methoxy-benzaldehyde | 2-hydroxy-4-met...)
Show SMILES COc1ccc(C=O)c(O)c1
Show InChI InChI=1S/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H3
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n/an/a 3.00E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase

Bioorg Med Chem Lett 14: 681-3 (2004)


BindingDB Entry DOI: 10.7270/Q27S7N6X
More data for this
Ligand-Target Pair
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))		BDBM50503716
PNG
(CHEMBL4453823)
Show SMILES OC[C@H]1O[C@@H](OCCc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H20O8/c15-6-10-11(18)12(19)13(20)14(22-10)21-4-3-7-1-2-8(16)5-9(7)17/h1-2,5,10-20H,3-4,6H2/t10-,11-,12+,13-,14-/m1/s1
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n/an/a 3.59E+4n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using TBC as substrate by spectrophotometric method

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50139366
PNG
(4-Isopropyl-benzaldehyde | 4-isopropylbenzaldehyde...)
Show SMILES CC(C)c1ccc(C=O)cc1
Show InChI InChI=1S/C10H12O/c1-8(2)10-5-3-9(7-11)4-6-10/h3-8H,1-2H3
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n/an/a 5.00E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase

Bioorg Med Chem Lett 14: 681-3 (2004)


BindingDB Entry DOI: 10.7270/Q27S7N6X
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50031467
PNG
(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Show SMILES OCc1cc(=O)c(O)co1
Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
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n/an/a 2.80E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity against mushroom tyrosinase (approximate value given)

Bioorg Med Chem Lett 13: 2409-12 (2003)


BindingDB Entry DOI: 10.7270/Q2HD7W6H
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50139370
PNG
(4-Methoxy-benzaldehyde | 4-methoxybenzaldehyde | C...)
Show SMILES COc1ccc(C=O)cc1
Show InChI InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3
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n/an/a 3.20E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase

Bioorg Med Chem Lett 14: 681-3 (2004)


BindingDB Entry DOI: 10.7270/Q27S7N6X
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50503715
PNG
(CHEMBL4586957)
Show SMILES OC[C@H]1O[C@@H](Oc2ccc(O)cc2O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C12H16O8/c13-4-8-9(16)10(17)11(18)12(20-8)19-7-2-1-5(14)3-6(7)15/h1-3,8-18H,4H2/t8-,9-,10+,11-,12-/m1/s1
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n/an/a 4.17E+5n/an/an/an/an/an/a



Utsunomiya University

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase (unknown origin) using L-DOPA as substrate preincubated with substrate for 5 mins followed by enzyme addition and measured i...

Bioorg Med Chem Lett 29: 313-316 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.029
BindingDB Entry DOI: 10.7270/Q22V2KCK
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM60953
PNG
(BDBM50139371 | benzaldehyde)
Show SMILES O=Cc1ccccc1
Show InChI InChI=1S/C7H6O/c8-6-7-4-2-1-3-5-7/h1-6H
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n/an/a 8.20E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase

Bioorg Med Chem Lett 14: 681-3 (2004)


BindingDB Entry DOI: 10.7270/Q27S7N6X
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM50139367
PNG
(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Show SMILES Oc1ccccc1C=O
Show InChI InChI=1S/C7H6O2/c8-5-6-3-1-2-4-7(6)9/h1-5,9H
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n/an/a 3.30E+6n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinase

Bioorg Med Chem Lett 14: 681-3 (2004)


BindingDB Entry DOI: 10.7270/Q27S7N6X
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))		BDBM60928
PNG
(BDBM50130192 | L-3,4-dihydroxyphenylalanine | L-DO...)
Show SMILES N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O |r|
Show InChI InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1
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n/an/a 8.40E+6n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibitory activity against mushroom tyrosinase

Bioorg Med Chem Lett 13: 2409-12 (2003)


BindingDB Entry DOI: 10.7270/Q2HD7W6H
More data for this
Ligand-Target Pair
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