Compile Data Set for Download or QSAR

Found 278 hits with Last Name = 'schudok' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Homo sapiens (Human))	BDBM109847 (US8609681, 70) Show SMILES FC(F)(C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N)Cc1ccccc1 |r| Show InChI InChI=1S/C23H28F2N4O2/c24-23(25,14-17-4-2-1-3-5-17)15-18(19(30)28-22(16-26)8-9-22)27-20(31)29-12-10-21(6-7-21)11-13-29/h1-5,18H,6-15H2,(H,27,31)(H,28,30)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109859 (US8609681, 102) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-2-3-19(20,21)12-14(15(26)24-18(13-22)6-7-18)23-16(27)25-10-8-17(4-5-17)9-11-25/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109858 (US8609681, 97) Show SMILES FC(F)(C[C@H](NC(=O)N1CCC2(CCN(CC2)C2CC2)CC1)C(=O)NC1(CC1)C#N)Cc1ccccc1 |r| Show InChI InChI=1S/C28H37F2N5O2/c29-28(30,18-21-4-2-1-3-5-21)19-23(24(36)33-27(20-31)8-9-27)32-25(37)35-16-12-26(13-17-35)10-14-34(15-11-26)22-6-7-22/h1-5,22-23H,6-19H2,(H,32,37)(H,33,36)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109862 (US8609681, 9) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCCCC2)CC1)C(=O)NC1(CC1)C#N Show InChI InChI=1S/C20H30F2N4O2/c1-18(21,22)13-15(16(27)25-20(14-23)7-8-20)24-17(28)26-11-9-19(10-12-26)5-3-2-4-6-19/h15H,2-13H2,1H3,(H,24,28)(H,25,27)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109857 (US8609681, 94) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CCN(CC2)C2CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H37F2N5O2/c1-2-5-24(25,26)16-19(20(32)29-23(17-27)6-7-23)28-21(33)31-14-10-22(11-15-31)8-12-30(13-9-22)18-3-4-18/h18-19H,2-16H2,1H3,(H,28,33)(H,29,32)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109839 (US8609681, 36) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCCC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-17(20,21)12-14(15(26)24-19(13-22)6-7-19)23-16(27)25-10-8-18(9-11-25)4-2-3-5-18/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109856 (US8609681, 91) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CCN(C2)c2ccc(OC)cc2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C27H37F2N5O3/c1-3-8-27(28,29)17-22(23(35)32-26(18-30)9-10-26)31-24(36)33-14-11-25(12-15-33)13-16-34(19-25)20-4-6-21(37-2)7-5-20/h4-7,22H,3,8-17,19H2,1-2H3,(H,31,36)(H,32,35)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109839 (US8609681, 36) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCCC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-17(20,21)12-14(15(26)24-19(13-22)6-7-19)23-16(27)25-10-8-18(9-11-25)4-2-3-5-18/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109862 (US8609681, 9) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCCCC2)CC1)C(=O)NC1(CC1)C#N Show InChI InChI=1S/C20H30F2N4O2/c1-18(21,22)13-15(16(27)25-20(14-23)7-8-20)24-17(28)26-11-9-19(10-12-26)5-3-2-4-6-19/h15H,2-13H2,1H3,(H,24,28)(H,25,27)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109844 (US8609681, 53) Show SMILES O=C(NC1(CCCCC1)C(=O)NC1(CC1)C#N)N1CCC2(CCCC2)CC1 Show InChI InChI=1S/C21H32N4O2/c22-16-20(10-11-20)23-17(26)21(8-2-1-3-9-21)24-18(27)25-14-12-19(13-15-25)6-4-5-7-19/h1-15H2,(H,23,26)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109846 (US8609681, 63) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H24F2N4O2/c1-15(18,19)10-12(13(24)22-17(11-20)4-5-17)21-14(25)23-8-6-16(2-3-16)7-9-23/h12H,2-10H2,1H3,(H,21,25)(H,22,24)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109850 (US8609681, 77) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(C1)CCCCC2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-17(20,21)11-14(15(26)24-19(12-22)7-8-19)23-16(27)25-10-9-18(13-25)5-3-2-4-6-18/h14H,2-11,13H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109845 (US8609681, 56) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCN(CC2)C2CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C22H33F2N5O2/c1-20(23,24)14-17(18(30)27-22(15-25)4-5-22)26-19(31)29-12-8-21(9-13-29)6-10-28(11-7-21)16-2-3-16/h16-17H,2-14H2,1H3,(H,26,31)(H,27,30)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109845 (US8609681, 56) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCN(CC2)C2CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C22H33F2N5O2/c1-20(23,24)14-17(18(30)27-22(15-25)4-5-22)26-19(31)29-12-8-21(9-13-29)6-10-28(11-7-21)16-2-3-16/h16-17H,2-14H2,1H3,(H,26,31)(H,27,30)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109854 (US8609681, 83) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CC2(C1)CCN(CC2)C1CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C20H29F2N5O2/c1-18(21,22)10-15(16(28)25-20(11-23)4-5-20)24-17(29)27-12-19(13-27)6-8-26(9-7-19)14-2-3-14/h14-15H,2-10,12-13H2,1H3,(H,24,29)(H,25,28)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109852 (US8609681, 79) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(C1)CCCc1ccccc21)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H28F2N4O2/c1-21(24,25)13-18(19(30)28-23(14-26)9-10-23)27-20(31)29-12-11-22(15-29)8-4-6-16-5-2-3-7-17(16)22/h2-3,5,7,18H,4,6,8-13,15H2,1H3,(H,27,31)(H,28,30)/t18-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109853 (US8609681, 80) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCOC11CCCCC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C18H26F2N4O3/c1-16(19,20)11-13(14(25)23-17(12-21)7-8-17)22-15(26)24-9-10-27-18(24)5-3-2-4-6-18/h13H,2-11H2,1H3,(H,22,26)(H,23,25)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109855 (US8609681, 88) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CN(CC3CC3)C(=O)C2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C22H31F2N5O3/c1-20(23,24)10-16(18(31)27-22(13-25)4-5-22)26-19(32)28-8-6-21(7-9-28)11-17(30)29(14-21)12-15-2-3-15/h15-16H,2-12,14H2,1H3,(H,26,32)(H,27,31)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109841 (US8609681, 42) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)N(CNC2=O)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H28F2N6O3/c1-21(24,25)13-17(18(32)29-22(14-26)7-8-22)28-20(34)30-11-9-23(10-12-30)19(33)27-15-31(23)16-5-3-2-4-6-16/h2-6,17H,7-13,15H2,1H3,(H,27,33)(H,28,34)(H,29,32)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148952 (CHEMBL429152 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C31H30N6O4/c1-20(35-28(38)19-34-31(40)37-25-16-12-22(13-17-25)29(32)33)21-10-14-24(15-11-21)36-30(39)23-6-5-9-27(18-23)41-26-7-3-2-4-8-26/h2-18,20H,19H2,1H3,(H3,32,33)(H,35,38)(H,36,39)(H2,34,37,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148947 (CHEMBL339880 | Piperidine-4-carboxylic acid [4-(1-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)C2CCNCC2)cc1 Show InChI InChI=1S/C24H31N7O3/c1-15(16-2-6-19(7-3-16)30-23(33)18-10-12-27-13-11-18)29-21(32)14-28-24(34)31-20-8-4-17(5-9-20)22(25)26/h2-9,15,18,27H,10-14H2,1H3,(H3,25,26)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109840 (US8609681, 37) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)OCCO2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H24F2N4O4/c1-15(18,19)10-12(13(24)22-16(11-20)2-3-16)21-14(25)23-6-4-17(5-7-23)26-8-9-27-17/h12H,2-10H2,1H3,(H,21,25)(H,22,24)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148950 (CHEMBL332753 | N-[1-(3-Bromo-4-morpholin-4-yl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(Br)c1 Show InChI InChI=1S/C22H27BrN6O3/c1-14(16-4-7-19(18(23)12-16)29-8-10-32-11-9-29)27-20(30)13-26-22(31)28-17-5-2-15(3-6-17)21(24)25/h2-7,12,14H,8-11,13H2,1H3,(H3,24,25)(H,27,30)(H2,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109855 (US8609681, 88) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CN(CC3CC3)C(=O)C2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C22H31F2N5O3/c1-20(23,24)10-16(18(31)27-22(13-25)4-5-22)26-19(32)28-8-6-21(7-9-28)11-17(30)29(14-21)12-15-2-3-15/h15-16H,2-12,14H2,1H3,(H,26,32)(H,27,31)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109843 (US8609681, 49) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCN(Cc3ccccc3)C2=O)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C25H31F2N5O3/c1-23(26,27)15-19(20(33)30-25(17-28)7-8-25)29-22(35)31-12-9-24(10-13-31)11-14-32(21(24)34)16-18-5-3-2-4-6-18/h2-6,19H,7-16H2,1H3,(H,29,35)(H,30,33)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109852 (US8609681, 79) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(C1)CCCc1ccccc21)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H28F2N4O2/c1-21(24,25)13-18(19(30)28-23(14-26)9-10-23)27-20(31)29-12-11-22(15-29)8-4-6-16-5-2-3-7-17(16)22/h2-3,5,7,18H,4,6,8-13,15H2,1H3,(H,27,31)(H,28,30)/t18-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109848 (US8609681, 74) Show SMILES CC(F)(F)C[C@H](NS(=O)(=O)N1CCC2(CCCC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C18H28F2N4O3S/c1-16(19,20)12-14(15(25)22-18(13-21)6-7-18)23-28(26,27)24-10-8-17(9-11-24)4-2-3-5-17/h14,23H,2-12H2,1H3,(H,22,25)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109851 (US8609681, 78) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)OCc1ccccc21)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C22H26F2N4O3/c1-20(23,24)12-17(18(29)27-21(14-25)6-7-21)26-19(30)28-10-8-22(9-11-28)16-5-3-2-4-15(16)13-31-22/h2-5,17H,6-13H2,1H3,(H,26,30)(H,27,29)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148945 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-m...) Show SMILES COc1cccc(COc2ccc(cc2)C(C)NC(=O)CNC(=O)Nc2ccc(cc2)C(N)=N)c1 Show InChI InChI=1S/C26H29N5O4/c1-17(19-8-12-22(13-9-19)35-16-18-4-3-5-23(14-18)34-2)30-24(32)15-29-26(33)31-21-10-6-20(7-11-21)25(27)28/h3-14,17H,15-16H2,1-2H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109850 (US8609681, 77) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(C1)CCCCC2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-17(20,21)11-14(15(26)24-19(12-22)7-8-19)23-16(27)25-10-9-18(13-25)5-3-2-4-6-18/h14H,2-11,13H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148953 (4-(1-{2-[3-(4-Carbamimidoyl-phenyl)-ureido]-acetyl...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C25H26N6O3/c1-16(17-7-9-19(10-8-17)24(33)30-20-5-3-2-4-6-20)29-22(32)15-28-25(34)31-21-13-11-18(12-14-21)23(26)27/h2-14,16H,15H2,1H3,(H3,26,27)(H,29,32)(H,30,33)(H2,28,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109842 (US8609681, 45) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)NCC(C)(C)CO2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C20H31F2N5O3/c1-17(2)12-24-20(30-13-17)6-8-27(9-7-20)16(29)25-14(10-18(3,21)22)15(28)26-19(11-23)4-5-19/h14,24H,4-10,12-13H2,1-3H3,(H,25,29)(H,26,28)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109840 (US8609681, 37) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)OCCO2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H24F2N4O4/c1-15(18,19)10-12(13(24)22-16(11-20)2-3-16)21-14(25)23-6-4-17(5-7-23)26-8-9-27-17/h12H,2-10H2,1H3,(H,21,25)(H,22,24)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109846 (US8609681, 63) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H24F2N4O2/c1-15(18,19)10-12(13(24)22-17(11-20)4-5-17)21-14(25)23-8-6-16(2-3-16)7-9-23/h12H,2-10H2,1H3,(H,21,25)(H,22,24)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109849 (US8609681, 76) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CCC(C)(C)O2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C20H30F2N4O3/c1-17(2)4-7-20(29-17)8-10-26(11-9-20)16(28)24-14(12-18(3,21)22)15(27)25-19(13-23)5-6-19/h14H,4-12H2,1-3H3,(H,24,28)(H,25,27)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126575 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(3-oxo-...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H22N6O4/c1-11(13-4-7-16-15(8-13)26-18(28)10-30-16)24-17(27)9-23-20(29)25-14-5-2-12(3-6-14)19(21)22/h2-8,11H,9-10H2,1H3,(H3,21,22)(H,24,27)(H,26,28)(H2,23,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor VII (fVIIa)				Bioorg Med Chem Lett 13: 1463-7 (2003) BindingDB Entry DOI: 10.7270/Q2Q52P1B
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148958 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-{1-[4-(3-c...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(OCc2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H26ClN5O3/c1-16(18-7-11-22(12-8-18)34-15-17-3-2-4-20(26)13-17)30-23(32)14-29-25(33)31-21-9-5-19(6-10-21)24(27)28/h2-13,16H,14-15H2,1H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109857 (US8609681, 94) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CCN(CC2)C2CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C24H37F2N5O2/c1-2-5-24(25,26)16-19(20(32)29-23(17-27)6-7-23)28-21(33)31-14-10-22(11-15-31)8-12-30(13-9-22)18-3-4-18/h18-19H,2-16H2,1H3,(H,28,33)(H,29,32)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109842 (US8609681, 45) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)NCC(C)(C)CO2)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C20H31F2N5O3/c1-17(2)12-24-20(30-13-17)6-8-27(9-7-20)16(29)25-14(10-18(3,21)22)15(28)26-19(11-23)4-5-19/h14,24H,4-10,12-13H2,1-3H3,(H,25,29)(H,26,28)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148949 (CHEMBL339200 | N-[4-(1-{2-[3-(4-Carbamimidoyl-phen...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(NC(=O)c2cccc(C)c2)cc1 Show InChI InChI=1S/C26H28N6O3/c1-16-4-3-5-20(14-16)25(34)31-21-10-6-18(7-11-21)17(2)30-23(33)15-29-26(35)32-22-12-8-19(9-13-22)24(27)28/h3-14,17H,15H2,1-2H3,(H3,27,28)(H,30,33)(H,31,34)(H2,29,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148960 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-nap...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc2ccccc2c1 Show InChI InChI=1S/C22H23N5O2/c1-14(17-7-6-15-4-2-3-5-18(15)12-17)26-20(28)13-25-22(29)27-19-10-8-16(9-11-19)21(23)24/h2-12,14H,13H2,1H3,(H3,23,24)(H,26,28)(H2,25,27,29)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126571 (CHEMBL35586 | N-[(S)-1-(3-Bromo-phenyl)-ethyl]-2-[...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1cccc(Br)c1 Show InChI InChI=1S/C18H20BrN5O2/c1-11(13-3-2-4-14(19)9-13)23-16(25)10-22-18(26)24-15-7-5-12(6-8-15)17(20)21/h2-9,11H,10H2,1H3,(H3,20,21)(H,23,25)(H2,22,24,26)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor VII (fVIIa)				Bioorg Med Chem Lett 13: 1463-7 (2003) BindingDB Entry DOI: 10.7270/Q2Q52P1B
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM109860 (US8609681, 103) Show SMILES CN1CCC(CC1)(NC(=O)[C@H](CC(C)(F)F)NC(=O)N1CCC2(CC2)CC1)C#N |r| Show InChI InChI=1S/C20H31F2N5O2/c1-18(21,22)13-15(16(28)25-20(14-23)7-9-26(2)10-8-20)24-17(29)27-11-5-19(3-4-19)6-12-27/h15H,3-13H2,1-2H3,(H,24,29)(H,25,28)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin S. This protein is obtained as an inactive enzyme from R&D Systems...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126571 (CHEMBL35586 | N-[(S)-1-(3-Bromo-phenyl)-ethyl]-2-[...) Show SMILES C[C@H](NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1cccc(Br)c1 Show InChI InChI=1S/C18H20BrN5O2/c1-11(13-3-2-4-14(19)9-13)23-16(25)10-22-18(26)24-15-7-5-12(6-8-15)17(20)21/h2-9,11H,10H2,1H3,(H3,20,21)(H,23,25)(H2,22,24,26)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50126572 (CHEMBL35754 | N-[1-(2,4-Bis-trifluoromethyl-phenyl...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H19F6N5O2/c1-10(14-7-4-12(19(21,22)23)8-15(14)20(24,25)26)30-16(32)9-29-18(33)31-13-5-2-11(3-6-13)17(27)28/h2-8,10H,9H2,1H3,(H3,27,28)(H,30,32)(H2,29,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibitory activity against coagulation factor VII (fVIIa)				Bioorg Med Chem Lett 13: 1463-7 (2003) BindingDB Entry DOI: 10.7270/Q2Q52P1B
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109854 (US8609681, 83) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CC2(C1)CCN(CC2)C1CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C20H29F2N5O2/c1-18(21,22)10-15(16(28)25-20(11-23)4-5-20)24-17(29)27-12-19(13-27)6-8-26(9-7-19)14-2-3-14/h14-15H,2-10,12-13H2,1H3,(H,24,29)(H,25,28)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50148954 (2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-[1-(4-morp...) Show SMILES CC(NC(=O)CNC(=O)Nc1ccc(cc1)C(N)=N)c1ccc(N2CCOCC2)c(c1)C(F)(F)F Show InChI InChI=1S/C23H27F3N6O3/c1-14(16-4-7-19(18(12-16)23(24,25)26)32-8-10-35-11-9-32)30-20(33)13-29-22(34)31-17-5-2-15(3-6-17)21(27)28/h2-7,12,14H,8-11,13H2,1H3,(H3,27,28)(H,30,33)(H2,29,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description In vitro inhibition of human coagulation factor VIIa				Bioorg Med Chem Lett 14: 3715-20 (2004) Article DOI: 10.1016/j.bmcl.2004.05.006 BindingDB Entry DOI: 10.7270/Q2PG1R6T
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109861 (US8609681, 35) Show SMILES CC(C)C[C@H](NC(=O)C1CCC2(CC1)OCCO2)C(=O)NC1(CC1)C#N Show InChI InChI=1S/C19H29N3O4/c1-13(2)11-15(17(24)22-18(12-20)7-8-18)21-16(23)14-3-5-19(6-4-14)25-9-10-26-19/h13-15H,3-11H2,1-2H3,(H,21,23)(H,22,24)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109841 (US8609681, 42) Show SMILES CC(F)(F)C[C@H](NC(=O)N1CCC2(CC1)N(CNC2=O)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C23H28F2N6O3/c1-21(24,25)13-17(18(32)29-22(14-26)7-8-22)28-20(34)30-11-9-23(10-12-30)19(33)27-15-31(23)16-5-3-2-4-6-16/h2-6,17H,7-13,15H2,1H3,(H,27,33)(H,28,34)(H,29,32)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM109859 (US8609681, 102) Show SMILES CCCC(F)(F)C[C@H](NC(=O)N1CCC2(CC2)CC1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C19H28F2N4O2/c1-2-3-19(20,21)12-14(15(26)24-18(13-22)6-7-18)23-16(27)25-10-8-17(4-5-17)9-11-25/h14H,2-12H2,1H3,(H,23,27)(H,24,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Determination of the enzymatic activity of the catalytic domain of human Cathepsin K. This protein is obtained as an inactive enzyme from Sanofi-Aven...				US Patent US8609681 (2013) BindingDB Entry DOI: 10.7270/Q2F47MSF
					More data for this Ligand-Target Pair

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