Compile Data Set for Download or QSAR

Found 67 hits with Last Name = 'savage' and Initial = 'ma'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001092 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C33H45N5O7S2/c1-18-13-21(39)14-19(2)22(18)16-23(34)28(41)37-26-30(43)35-17-25(40)36-24(15-20-11-9-8-10-12-20)29(42)38-27(31(44)45-7)33(5,6)47-46-32(26,3)4/h8-14,23-24,26-27,39H,15-17,34H2,1-7H3,(H,35,43)(H,36,40)(H,37,41)(H,38,42)/t23-,24+,26+,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001092 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C33H45N5O7S2/c1-18-13-21(39)14-19(2)22(18)16-23(34)28(41)37-26-30(43)35-17-25(40)36-24(15-20-11-9-8-10-12-20)29(42)38-27(31(44)45-7)33(5,6)47-46-32(26,3)4/h8-14,23-24,26-27,39H,15-17,34H2,1-7H3,(H,35,43)(H,36,40)(H,37,41)(H,38,42)/t23-,24+,26+,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50000335 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H](C(O)=O)C(C)(C)SSC1(C)C Show InChI InChI=1S/C32H43N5O7S2/c1-17-12-20(38)13-18(2)21(17)15-22(33)27(40)36-25-29(42)34-16-24(39)35-23(14-19-10-8-7-9-11-19)28(41)37-26(30(43)44)32(5,6)46-45-31(25,3)4/h7-13,22-23,25-26,38H,14-16,33H2,1-6H3,(H,34,42)(H,35,39)(H,36,40)(H,37,41)(H,43,44)/t22-,23+,25+,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLET				J Med Chem 35: 684-7 (1992) BindingDB Entry DOI: 10.7270/Q2FB53JD
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001090 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES COC(=O)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C Show InChI InChI=1S/C31H41N5O7S2/c1-30(2)24(35-26(39)21(32)15-19-11-13-20(37)14-12-19)28(41)33-17-23(38)34-22(16-18-9-7-6-8-10-18)27(40)36-25(29(42)43-5)31(3,4)45-44-30/h6-14,21-22,24-25,37H,15-17,32H2,1-5H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)/t21-,22+,24+,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001088 ((DPDPE)13-[2-Amino-3-(4-hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23+,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001090 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES COC(=O)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C Show InChI InChI=1S/C31H41N5O7S2/c1-30(2)24(35-26(39)21(32)15-19-11-13-20(37)14-12-19)28(41)33-17-23(38)34-22(16-18-9-7-6-8-10-18)27(40)36-25(29(42)43-5)31(3,4)45-44-30/h6-14,21-22,24-25,37H,15-17,32H2,1-5H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)/t21-,22+,24+,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001093 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)CCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C34H48N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-10,12-13,16-17,23,26-28,39H,11,14-15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001093 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)CCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C34H48N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-10,12-13,16-17,23,26-28,39H,11,14-15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001683 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In Vitro evaluation for the binding affinity in homogenates of rat brain at Opioid receptor delta 1 by displacing [3H]- DSLET				J Med Chem 35: 684-7 (1992) BindingDB Entry DOI: 10.7270/Q2FB53JD
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001093 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)CCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C34H48N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-10,12-13,16-17,23,26-28,39H,11,14-15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001093 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)CCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C34H48N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-10,12-13,16-17,23,26-28,39H,11,14-15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001089 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)\C=C/CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C |c:17| Show InChI InChI=1S/C34H46N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-14,16-17,23,26-28,39H,15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/b14-11-/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Dissociation rate constant of compound for mutant T46S Escherichia coli dihydrofolate reductase				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001089 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)\C=C/CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C |c:17| Show InChI InChI=1S/C34H46N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-14,16-17,23,26-28,39H,15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/b14-11-/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001089 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)\C=C/CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C |c:17| Show InChI InChI=1S/C34H46N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-14,16-17,23,26-28,39H,15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/b14-11-/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001089 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)\C=C/CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C |c:17| Show InChI InChI=1S/C34H46N4O6S2/c1-20-16-24(39)17-21(2)25(20)19-26(35)30(41)37-27-31(42)36-15-11-14-23(18-22-12-9-8-10-13-22)29(40)38-28(32(43)44-7)34(5,6)46-45-33(27,3)4/h8-14,16-17,23,26-28,39H,15,18-19,35H2,1-7H3,(H,36,42)(H,37,41)(H,38,40)/b14-11-/t23?,26-,27+,28+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50000335 (13-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H](C(O)=O)C(C)(C)SSC1(C)C Show InChI InChI=1S/C32H43N5O7S2/c1-17-12-20(38)13-18(2)21(17)15-22(33)27(40)36-25-29(42)34-16-24(39)35-23(14-19-10-8-7-9-11-19)28(41)37-26(30(43)44)32(5,6)46-45-31(25,3)4/h7-13,22-23,25-26,38H,14-16,33H2,1-6H3,(H,34,42)(H,35,39)(H,36,40)(H,37,41)(H,43,44)/t22-,23+,25+,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGO				J Med Chem 35: 684-7 (1992) BindingDB Entry DOI: 10.7270/Q2FB53JD
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001091 (10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)OCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C33H46N4O7S2/c1-19-15-22(38)16-20(2)23(19)18-24(34)28(39)36-26-30(41)35-13-14-44-25(17-21-11-9-8-10-12-21)29(40)37-27(31(42)43-7)33(5,6)46-45-32(26,3)4/h8-12,15-16,24-27,38H,13-14,17-18,34H2,1-7H3,(H,35,41)(H,36,39)(H,37,40)/t24-,25?,26+,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Dissociation rate constant of compound for mutant T46A Escherichia coli dihydrofolate reductase				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001091 (10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)OCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C33H46N4O7S2/c1-19-15-22(38)16-20(2)23(19)18-24(34)28(39)36-26-30(41)35-13-14-44-25(17-21-11-9-8-10-12-21)29(40)37-27(31(42)43-7)33(5,6)46-45-32(26,3)4/h8-12,15-16,24-27,38H,13-14,17-18,34H2,1-7H3,(H,35,41)(H,36,39)(H,37,40)/t24-,25?,26+,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement [3H]- DSLET from Opioid receptor delta 1 by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001091 (10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)OCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C33H46N4O7S2/c1-19-15-22(38)16-20(2)23(19)18-24(34)28(39)36-26-30(41)35-13-14-44-25(17-21-11-9-8-10-12-21)29(40)37-27(31(42)43-7)33(5,6)46-45-32(26,3)4/h8-12,15-16,24-27,38H,13-14,17-18,34H2,1-7H3,(H,35,41)(H,36,39)(H,37,40)/t24-,25?,26+,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001091 (10-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-prop...) Show SMILES COC(=O)[C@H]1NC(=O)C(Cc2ccccc2)OCCNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(C)(C)SSC1(C)C Show InChI InChI=1S/C33H46N4O7S2/c1-19-15-22(38)16-20(2)23(19)18-24(34)28(39)36-26-30(41)35-13-14-44-25(17-21-11-9-8-10-12-21)29(40)37-27(31(42)43-7)33(5,6)46-45-32(26,3)4/h8-12,15-16,24-27,38H,13-14,17-18,34H2,1-7H3,(H,35,41)(H,36,39)(H,37,40)/t24-,25?,26+,27+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001088 ((DPDPE)13-[2-Amino-3-(4-hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23+,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
G.D. Searle and Company Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacement of [3H]- DAMPGO from opioid receptor mu by using opioid radioligand binding assay				J Med Chem 35: 2928-38 (1992) BindingDB Entry DOI: 10.7270/Q2ST7QF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001683 (13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...) Show SMILES CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O Show InChI InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description In Vitro evaluation for the binding affinity in homogenates of rat brain at opioid receptor mu by displacing [3H]- DAMGO				J Med Chem 35: 684-7 (1992) BindingDB Entry DOI: 10.7270/Q2FB53JD
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453625 (CHEMBL2110229) Show SMILES C[C@@H](N(C)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-22(25)24(30)27(4)18(3)23(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,22,28H,8,11-12,15,25H2,1-4H3,(H,26,29)/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C23H31N3O3/c1-15-12-19(27)13-16(2)20(15)14-21(24)23(29)26-17(3)22(28)25-11-7-10-18-8-5-4-6-9-18/h4-6,8-9,12-13,17,21,27H,7,10-11,14,24H2,1-3H3,(H,25,28)(H,26,29)/t17-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C23H31N3O3/c1-15-12-19(27)13-16(2)20(15)14-21(24)23(29)26-17(3)22(28)25-11-7-10-18-8-5-4-6-9-18/h4-6,8-9,12-13,17,21,27H,7,10-11,14,24H2,1-3H3,(H,25,28)(H,26,29)/t17-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453625 (CHEMBL2110229) Show SMILES C[C@@H](N(C)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-22(25)24(30)27(4)18(3)23(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,22,28H,8,11-12,15,25H2,1-4H3,(H,26,29)/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453616 (CHEMBL2110337) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(OCc2ccccc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H37N3O3/c1-21-17-26(36-20-25-13-8-5-9-14-25)18-22(2)27(21)19-28(31)30(35)33-23(3)29(34)32-16-10-15-24-11-6-4-7-12-24/h4-9,11-14,17-18,23,28H,10,15-16,19-20,31H2,1-3H3,(H,32,34)(H,33,35)/t23-,28+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036790 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) Show SMILES C[C@@H](NC(=O)C(C)(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-24(4,25)23(30)27-18(3)22(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,28H,8,11-12,15,25H2,1-4H3,(H,26,29)(H,27,30)/t18-,24?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036790 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) Show SMILES C[C@@H](NC(=O)C(C)(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-24(4,25)23(30)27-18(3)22(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,28H,8,11-12,15,25H2,1-4H3,(H,26,29)(H,27,30)/t18-,24?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036806 (2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(cc2)[N+]([O-])=O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H36N4O5/c1-20-16-26(39-19-24-11-13-25(14-12-24)34(37)38)17-21(2)27(20)18-28(31)30(36)33-22(3)29(35)32-15-7-10-23-8-5-4-6-9-23/h4-6,8-9,11-14,16-17,22,28H,7,10,15,18-19,31H2,1-3H3,(H,32,35)(H,33,36)/t22-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453616 (CHEMBL2110337) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(OCc2ccccc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H37N3O3/c1-21-17-26(36-20-25-13-8-5-9-14-25)18-22(2)27(21)19-28(31)30(35)33-23(3)29(34)32-16-10-15-24-11-6-4-7-12-24/h4-9,11-14,17-18,23,28H,10,15-16,19-20,31H2,1-3H3,(H,32,34)(H,33,35)/t23-,28+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50453625 (CHEMBL2110229) Show SMILES C[C@@H](N(C)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-22(25)24(30)27(4)18(3)23(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,22,28H,8,11-12,15,25H2,1-4H3,(H,26,29)/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50453625 (CHEMBL2110229) Show SMILES C[C@@H](N(C)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-22(25)24(30)27(4)18(3)23(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,22,28H,8,11-12,15,25H2,1-4H3,(H,26,29)/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C23H31N3O3/c1-15-12-19(27)13-16(2)20(15)14-21(24)23(29)26-17(3)22(28)25-11-7-10-18-8-5-4-6-9-18/h4-6,8-9,12-13,17,21,27H,7,10-11,14,24H2,1-3H3,(H,25,28)(H,26,29)/t17-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036793 (2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(F)cc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H36FN3O3/c1-20-16-26(37-19-24-11-13-25(31)14-12-24)17-21(2)27(20)18-28(32)30(36)34-22(3)29(35)33-15-7-10-23-8-5-4-6-9-23/h4-6,8-9,11-14,16-17,22,28H,7,10,15,18-19,32H2,1-3H3,(H,33,35)(H,34,36)/t22-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C23H31N3O3/c1-15-12-19(27)13-16(2)20(15)14-21(24)23(29)26-17(3)22(28)25-11-7-10-18-8-5-4-6-9-18/h4-6,8-9,12-13,17,21,27H,7,10-11,14,24H2,1-3H3,(H,25,28)(H,26,29)/t17-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036805 (4-(4-{2-Amino-2-[(R)-1-(3-phenyl-propylcarbamoyl)-...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(cc2)C(O)=O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C31H37N3O5/c1-20-16-26(39-19-24-11-13-25(14-12-24)31(37)38)17-21(2)27(20)18-28(32)30(36)34-22(3)29(35)33-15-7-10-23-8-5-4-6-9-23/h4-6,8-9,11-14,16-17,22,28H,7,10,15,18-19,32H2,1-3H3,(H,33,35)(H,34,36)(H,37,38)/t22-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12.3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036793 (2-Amino-3-[4-(4-fluoro-benzyloxy)-2,6-dimethyl-phe...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(F)cc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H36FN3O3/c1-20-16-26(37-19-24-11-13-25(31)14-12-24)17-21(2)27(20)18-28(32)30(36)34-22(3)29(35)33-15-7-10-23-8-5-4-6-9-23/h4-6,8-9,11-14,16-17,22,28H,7,10,15,18-19,32H2,1-3H3,(H,33,35)(H,34,36)/t22-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036802 ((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...) Show SMILES C[C@@H](N(CC1CC1)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C27H37N3O3/c1-18-14-23(31)15-19(2)24(18)16-25(28)27(33)30(17-22-11-12-22)20(3)26(32)29-13-7-10-21-8-5-4-6-9-21/h4-6,8-9,14-15,20,22,25,31H,7,10-13,16-17,28H2,1-3H3,(H,29,32)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036802 ((S)-2-Amino-N-cyclopropylmethyl-3-(4-hydroxy-2,6-d...) Show SMILES C[C@@H](N(CC1CC1)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C27H37N3O3/c1-18-14-23(31)15-19(2)24(18)16-25(28)27(33)30(17-22-11-12-22)20(3)26(32)29-13-7-10-21-8-5-4-6-9-21/h4-6,8-9,14-15,20,22,25,31H,7,10-13,16-17,28H2,1-3H3,(H,29,32)/t20-,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50036797 (2-Amino-3-[4-(4-cyano-benzyloxy)-2,6-dimethyl-phen...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(cc2)C#N)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C31H36N4O3/c1-21-16-27(38-20-26-13-11-25(19-32)12-14-26)17-22(2)28(21)18-29(33)31(37)35-23(3)30(36)34-15-7-10-24-8-5-4-6-9-24/h4-6,8-9,11-14,16-17,23,29H,7,10,15,18,20,33H2,1-3H3,(H,34,36)(H,35,37)/t23-,29?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28.6	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453629 (CHEMBL170594) Show SMILES COc1cc(C)c(C[C@H](N)C(=O)N[C@H](C)C(=O)NCCCc2ccccc2)c(C)c1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(30-4)14-17(2)21(16)15-22(25)24(29)27-18(3)23(28)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,22H,8,11-12,15,25H2,1-4H3,(H,26,28)(H,27,29)/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453628 (CHEMBL2110227) Show SMILES C[C@@H](NC(=O)[C@H](N)Cc1c(C)cc(OCc2ccccc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H37N3O3/c1-21-17-26(36-20-25-13-8-5-9-14-25)18-22(2)27(21)19-28(31)30(35)33-23(3)29(34)32-16-10-15-24-11-6-4-7-12-24/h4-9,11-14,17-18,23,28H,10,15-16,19-20,31H2,1-3H3,(H,32,34)(H,33,35)/t23-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against mu opioid receptor by the displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50453616 (CHEMBL2110337) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(OCc2ccccc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H37N3O3/c1-21-17-26(36-20-25-13-8-5-9-14-25)18-22(2)27(21)19-28(31)30(35)33-23(3)29(34)32-16-10-15-24-11-6-4-7-12-24/h4-9,11-14,17-18,23,28H,10,15-16,19-20,31H2,1-3H3,(H,32,34)(H,33,35)/t23-,28+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50453629 (CHEMBL170594) Show SMILES COc1cc(C)c(C[C@H](N)C(=O)N[C@H](C)C(=O)NCCCc2ccccc2)c(C)c1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(30-4)14-17(2)21(16)15-22(25)24(29)27-18(3)23(28)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,22H,8,11-12,15,25H2,1-4H3,(H,26,28)(H,27,29)/t18-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Affinity for mu opioid receptor was measured by displacement of tritiated DAMGO from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50036790 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) Show SMILES C[C@@H](NC(=O)C(C)(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-24(4,25)23(30)27-18(3)22(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,28H,8,11-12,15,25H2,1-4H3,(H,26,29)(H,27,30)/t18-,24?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50036790 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-2-methyl...) Show SMILES C[C@@H](NC(=O)C(C)(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C24H33N3O3/c1-16-13-20(28)14-17(2)21(16)15-24(4,25)23(30)27-18(3)22(29)26-12-8-11-19-9-6-5-7-10-19/h5-7,9-10,13-14,18,28H,8,11-12,15,25H2,1-4H3,(H,26,29)(H,27,30)/t18-,24?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50036806 (2-Amino-3-[2,6-dimethyl-4-(4-nitro-benzyloxy)-phen...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(OCc2ccc(cc2)[N+]([O-])=O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H36N4O5/c1-20-16-26(39-19-24-11-13-25(14-12-24)34(37)38)17-21(2)27(20)18-28(31)30(36)33-22(3)29(35)32-15-7-10-23-8-5-4-6-9-23/h4-6,8-9,11-14,16-17,22,28H,7,10,15,18-19,31H2,1-3H3,(H,32,35)(H,33,36)/t22-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Displacement of [3H]-DSLET from rat brain membrane delta opioid receptor				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50453616 (CHEMBL2110337) Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(OCc2ccccc2)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C30H37N3O3/c1-21-17-26(36-20-25-13-8-5-9-14-25)18-22(2)27(21)19-28(31)30(35)33-23(3)29(34)32-16-10-15-24-11-6-4-7-12-24/h4-9,11-14,17-18,23,28H,10,15-16,19-20,31H2,1-3H3,(H,32,34)(H,33,35)/t23-,28+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against delta opioid receptor by the displacement of tritiated DSLET from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50036787 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-[(R)-1...) Show SMILES C[C@@H](NC(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C23H31N3O3/c1-15-12-19(27)13-16(2)20(15)14-21(24)23(29)26-17(3)22(28)25-11-7-10-18-8-5-4-6-9-18/h4-6,8-9,12-13,17,21,27H,7,10-11,14,24H2,1-3H3,(H,25,28)(H,26,29)/t17-,21?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
Searle Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated against kappa opioid receptor by displacement of tritiated U-69593 from rat brain membranes				J Med Chem 37: 888-96 (1994) BindingDB Entry DOI: 10.7270/Q27H1HN2
					More data for this Ligand-Target Pair

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