Compile Data Set for Download or QSAR

Found 29 hits with Last Name = 'patel' and Initial = 'mk'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259542 (2-(3-Trifluoromethylphenyl)-4(5)-(3-trifluoromethy...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H10F6N2/c18-16(19,20)12-5-1-3-10(7-12)14-9-24-15(25-14)11-4-2-6-13(8-11)17(21,22)23/h1-9H,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259388 (2-(4-Chlorophenyl)-4(5)-phenylimidazole | CHEMBL50...) Show SMILES Clc1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C15H11ClN2/c16-13-8-6-12(7-9-13)15-17-10-14(18-15)11-4-2-1-3-5-11/h1-10H,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259490 (2-Phenyl-4(5)-(4-trifluoromethylphenyl)imidazole |...) Show SMILES FC(F)(F)c1ccc(cc1)-c1c[nH]c(n1)-c1ccccc1 Show InChI InChI=1S/C16H11F3N2/c17-16(18,19)13-8-6-11(7-9-13)14-10-20-15(21-14)12-4-2-1-3-5-12/h1-10H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50365938 (CHEMBL1958460) Show SMILES CCCCCCCC(O)(C(N)=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H22ClNO2/c1-2-3-4-5-6-10-15(19,14(17)18)12-8-7-9-13(16)11-12/h7-9,11,19H,2-6,10H2,1H3,(H2,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.7 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50365939 (CHEMBL1958461) Show SMILES CCCCCCC[C@](O)(C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H22ClNO2/c1-2-3-4-5-6-10-15(19,14(17)18)12-8-7-9-13(16)11-12/h7-9,11,19H,2-6,10H2,1H3,(H2,17,18)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.7 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259541 (2-(4-Nitrophenyl)-4(5)-(3-trifluoromethylphenyl)-i...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc(c[nH]1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H10F3N3O2/c17-16(18,19)12-3-1-2-11(8-12)14-9-20-15(21-14)10-4-6-13(7-5-10)22(23)24/h1-9H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50365940 (CHEMBL1958462) Show SMILES CCCCCCC[C@@](O)(C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H22ClNO2/c1-2-3-4-5-6-10-15(19,14(17)18)12-8-7-9-13(16)11-12/h7-9,11,19H,2-6,10H2,1H3,(H2,17,18)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.7 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50145044 (2-Phenyl-4(5)-(3-trifluoromethylphenyl)imidazole |...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1ccccc1 Show InChI InChI=1S/C16H11F3N2/c17-16(18,19)13-8-4-7-12(9-13)14-10-20-15(21-14)11-5-2-1-3-6-11/h1-10H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50365940 (CHEMBL1958462) Show SMILES CCCCCCC[C@@](O)(C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H22ClNO2/c1-2-3-4-5-6-10-15(19,14(17)18)12-8-7-9-13(16)11-12/h7-9,11,19H,2-6,10H2,1H3,(H2,17,18)/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.5 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50365938 (CHEMBL1958460) Show SMILES CCCCCCCC(O)(C(N)=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H22ClNO2/c1-2-3-4-5-6-10-15(19,14(17)18)12-8-7-9-13(16)11-12/h7-9,11,19H,2-6,10H2,1H3,(H2,17,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.5 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50365939 (CHEMBL1958461) Show SMILES CCCCCCC[C@](O)(C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H22ClNO2/c1-2-3-4-5-6-10-15(19,14(17)18)12-8-7-9-13(16)11-12/h7-9,11,19H,2-6,10H2,1H3,(H2,17,18)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.5 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330764 (2-(4-Trifluoromethylphenyl)-4(5)-phenylimidazole |...) Show SMILES FC(F)(F)c1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H11F3N2/c17-16(18,19)13-8-6-12(7-9-13)15-20-10-14(21-15)11-4-2-1-3-5-11/h1-10H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330765 (2-Phenyl-4(5)-(3-chlorophenyl)imidazole | 4-(3-chl...) Show SMILES Clc1cccc(c1)-c1c[nH]c(n1)-c1ccccc1 Show InChI InChI=1S/C15H11ClN2/c16-13-8-4-7-12(9-13)14-10-17-15(18-14)11-5-2-1-3-6-11/h1-10H,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50330763 (2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...) Show SMILES COc1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O/c1-19-14-9-7-13(8-10-14)16-17-11-15(18-16)12-5-3-2-4-6-12/h2-11H,1H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50330763 (2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...) Show SMILES COc1ccc(cc1)-c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O/c1-19-14-9-7-13(8-10-14)16-17-11-15(18-16)12-5-3-2-4-6-12/h2-11H,1H3,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392415 (CHEMBL402642) Show SMILES C(Oc1ccccc1)c1cn(nn1)-c1ccccc1 Show InChI InChI=1S/C15H13N3O/c1-3-7-14(8-4-1)18-11-13(16-17-18)12-19-15-9-5-2-6-10-15/h1-11H,12H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392416 (CHEMBL2151778) Show SMILES C(COc1ccccc1)Cc1cn(Cc2ccccc2)nn1 Show InChI InChI=1S/C18H19N3O/c1-3-8-16(9-4-1)14-21-15-17(19-20-21)10-7-13-22-18-11-5-2-6-12-18/h1-6,8-9,11-12,15H,7,10,13-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50133778 (2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...) Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50133778 (2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...) Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50133778 (2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...) Show SMILES c1[nH]c(nc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392417 (CHEMBL2151781) Show SMILES C(COc1ccccc1)Cc1cn(CCc2ccccc2)nn1 Show InChI InChI=1S/C19H21N3O/c1-3-8-17(9-4-1)13-14-22-16-18(20-21-22)10-7-15-23-19-11-5-2-6-12-19/h1-6,8-9,11-12,16H,7,10,13-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50392418 (CHEMBL2151783) Show SMILES O=C(Cn1cc(CCCOc2ccccc2)nn1)c1ccccc1 Show InChI InChI=1S/C19H19N3O2/c23-19(16-8-3-1-4-9-16)15-22-14-17(20-21-22)10-7-13-24-18-11-5-2-6-12-18/h1-6,8-9,11-12,14H,7,10,13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50259540 (2-(4-Chlorophenyl)-4(5)-(3-trifluoromethylphenyl)-...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H10ClF3N2/c17-13-6-4-10(5-7-13)15-21-9-14(22-15)11-2-1-3-12(8-11)16(18,19)20/h1-9H,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50003655 (Phenytoin) Show SMILES O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.7 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50003655 (Phenytoin) Show SMILES O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of human voltage-gated sodium channel 1.5 expressed in HEK293 cells assessed as changes in membranre potential after 45 mins by FRET analy...				Bioorg Med Chem 20: 2180-8 (2012) Article DOI: 10.1016/j.bmc.2011.08.061 BindingDB Entry DOI: 10.7270/Q2377961
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50003655 (Phenytoin) Show SMILES O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording technique				Bioorg Med Chem 18: 7957-65 (2010) Article DOI: 10.1016/j.bmc.2010.09.029 BindingDB Entry DOI: 10.7270/Q26973T7
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50031299 (6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...) Show SMILES Nc1nnc(c(N)n1)-c1cccc(Cl)c1Cl Show InChI InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Homo sapiens (Human))	BDBM50003655 (Phenytoin) Show SMILES O=C1NC(=O)C(N1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method				Bioorg Med Chem 17: 3642-8 (2009) Article DOI: 10.1016/j.bmc.2009.03.067 BindingDB Entry DOI: 10.7270/Q2GQ6XN5
					More data for this Ligand-Target Pair
Sodium channel protein type 8 subunit alpha (Rattus norvegicus)	BDBM50351882 (CHEMBL1825043) Show SMILES C(c1ccccc1)n1cc(nn1)-c1ccccc1 Show InChI InChI=1S/C15H13N3/c1-3-7-13(8-4-1)11-18-12-15(16-17-18)14-9-5-2-6-10-14/h1-10,12H,11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of rat NaV1.6-mediated current expressed in human HEK293 cells by patch clamp assay				Bioorg Med Chem Lett 22: 6401-4 (2012) Article DOI: 10.1016/j.bmcl.2012.08.067 BindingDB Entry DOI: 10.7270/Q2TX3GGK
					More data for this Ligand-Target Pair