BindingDB PrimarySearch

Found 325 hits with Last Name = 'mahindroo' and Initial = 'n'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265158 (CHEMBL497992 \| N-((trans)-4-((S)-1-amino-2-oxo-2-(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249185 (4-(4-cyclopropylquinazolin-2-ylamino)-N-(2,6-dimet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249522 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249186 (CHEMBL472802 \| N-(2,6-dimethylphenyl)-4-(4-phenylp...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249184 (CHEMBL515093 \| N-(1-methyl-1,2,3,4-tetrahydroquino...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50148637 (5-(aminomethyl)-6-(2,4-dichlorophenyl)-N2-(2-metho...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265159 (CHEMBL497993 \| P-[(3S)-3-amino-2-oxopyrrolidin-1-y...) Show SMILES N[C@H]1CCN(C1=O)P(N)(N)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265160 (1-(2-amino-2-cyclohexylacetyl)pyrrolidine-2-carbon...) Show SMILES NC(C1CCCCC1)C(=O)N1CCCC1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11162 ((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249488 (4-benzyl-N-((3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265161 (CHEMBL496960 \| amino((S)-3-amino-2-oxopiperidin-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265264 (CHEMBL522909 \| N,N-diallyl-3-(bicyclo[2.2.1]heptan...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11113 (6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50185944 (CHEMBL208472 \| N-(1-(4-fluorophenyl)-3-(thiophen-2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from PPARgamma by SPA				J Med Chem 49: 2703-12 (2006) Article DOI: 10.1021/jm051129s BindingDB Entry DOI: 10.7270/Q2736QHH
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265199 (CHEMBL495932 \| amino((S)-3-amino-2-oxoazepan-1-yl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249523 (CHEMBL514622 \| N-(4-ethoxyphenyl)-4-(2-methylimida...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249489 (CHEMBL514344 \| N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265200 ((2S)-2-amino-1-((S)-3-fluoropyrrolidin-1-yl)-2-(2-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265080 ((S)-1-(2-amino-4-(isoindolin-2-yl)-4-oxobut-2-enoy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50181911 ((5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265201 ((S)-1-(2-((S)-1-(2-methyl-1H-indol-1-yl)propan-2-y...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140541 ((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC(F)(F)C1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50179236 (2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]L-783,483 from human PPAR delta by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249556 (CHEMBL511979 \| N-(5-chloro-2-methoxyphenyl)-4-(pyr...) Show SMILES COc1ccc(Cl)cc1Nc1nc(cs1)-c1cccnc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249555 (4-(pyridin-2-yl)-N-p-tolylthiazol-2-amine \| CHEMBL...) Show SMILES Cc1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249553 (CHEMBL511978 \| N-(4-(2-methylimidazo[1,2-a]pyridin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50474621 (CHEMBL8953) Show SMILES COc1cc(cc(OC)c1OC)C(=O)c1cc(Cl)ccc1N Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibitory concentration required against MAP-rich tubulin polymerization				J Med Chem 47: 2897-905 (2004) Article DOI: 10.1021/jm0305974 BindingDB Entry DOI: 10.7270/Q2RV0RGF
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249517 (6-cyclopropyl-4-(4-methoxyphenyl)-2-(2-oxopropylth...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Homo sapiens (Human))	BDBM50249519 (CHEMBL480889 \| N-((3S,5S)-1-(benzo[d][1,3]dioxol-5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of lipid-modified (octylated) form of SHH expressed in mouse s12 cells by luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249554 (1-(3-(4-phenylthiazol-2-ylamino)phenyl)ethanone \| ...) Show SMILES CC(=O)c1cccc(Nc2nc(cs2)-c2ccccc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179235 (2-{5-[4-(7-propyl-3-trifluoromethylbenzo[d]isoxazo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50241053 ((S)-2-amino-2-cyclohexyl-1-(3,3,4,4-tetrafluoropyr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50181911 ((5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]L-783,483 from human PPAR alpha by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50181902 (2-(6-(3-(4-(4-fluorobenzoyl)phenoxy)propoxy)-1H-in...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]L-783,483 from human PPAR alpha by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179229 (2-{5-[3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179225 (2-{4-[3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50181903 (2-(5-(3-(4-(4-fluorobenzoyl)-2-propylphenoxy)propo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179236 (2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50179236 (2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 48: 8194-208 (2005) Article DOI: 10.1021/jm0506930 BindingDB Entry DOI: 10.7270/Q2R78DS5
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265202 ((2S)-2-amino-2-cyclohexyl-1-(3-fluoropyrrolidin-1-...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC(F)C1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50185942 ((N-[1-(4-fluorophenyl)-3-(2-thienyl)-1H-pyrazol-5-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from PPARgamma by SPA				J Med Chem 49: 2703-12 (2006) Article DOI: 10.1021/jm051129s BindingDB Entry DOI: 10.7270/Q2736QHH
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50249518 ((E)-3-(4-(5-pentylpyridin-2-yl)phenyl)-1-(piperidi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assay				J Med Chem 52: 3829-45 (2009) Article DOI: 10.1021/jm801420y BindingDB Entry DOI: 10.7270/Q22N536M
St. Jude Children's Research Hospital Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50181913 (2-(5-(3-(4-(4-fluorobenzoyl)phenoxy)propoxy)-1H-in...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50181911 ((5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Displacement of [3H]L-783,483 from human PPAR delta by SPA assay				J Med Chem 49: 1212-6 (2006) Article DOI: 10.1021/jm0510373 BindingDB Entry DOI: 10.7270/Q2QV3M3P
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50265262 (3-(aminomethyl)-2-isobutyl-4-phenylisoquinolin-1(2...) Show SMILES CC(C)Cn1c(CN)c(-c2ccccc2)c2ccccc2c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human DPP4 expressed in baculovirus system				Eur J Med Chem 43: 1603-11 (2008) Article DOI: 10.1016/j.ejmech.2007.11.014 BindingDB Entry DOI: 10.7270/Q2V69JCD
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50474611 (CHEMBL99988) Show SMILES COc1ccc(cc1N)C(=O)c1cc(OC)c(OC)c(OC)c1 Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibitory concentration required against MAP-rich tubulin polymerization				J Med Chem 47: 2897-905 (2004) Article DOI: 10.1021/jm0305974 BindingDB Entry DOI: 10.7270/Q2RV0RGF
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50147362 (CHEMBL330407 \| ST-3100) Show SMILES COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1N Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibitory concentration required against MAP-rich tubulin polymerization				J Med Chem 47: 2897-905 (2004) Article DOI: 10.1021/jm0305974 BindingDB Entry DOI: 10.7270/Q2RV0RGF
National Health Research Institutes Curated by ChEMBL					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM11292 (1,5-dichloro-2-{[2,6-dinitro-4-(trifluoromethyl)be...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	7.0	25
National Defense Medical Center					Assay Description The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...				J Med Chem 49: 5154-61 (2006) Article DOI: 10.1021/jm060207o BindingDB Entry DOI: 10.7270/Q2M906V0
National Defense Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)

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