Found 258 hits with Last Name = 'marini' and Initial = 'p' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50067499
((6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-...)Show SMILES CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |r,c:18| Show InChI InChI=1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
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CHEMBL
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PC sid
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| Article
PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50067499
((6aR,10aR)-3(1,1-dimethylheptyl)-9-hydroxymethyl)-...)Show SMILES CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1 |r,c:18| Show InChI InChI=1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324652
(4-Oxo-1-pentyl-6-pyrrol-1-yl-1,4-dihydro-quinoline...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-n1cccc1 |TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:17:12:15.20.14,16:15:12:17.19.18| Show InChI InChI=1S/C29H35N3O2/c1-2-3-4-11-32-19-25(27(33)24-15-23(7-8-26(24)32)31-9-5-6-10-31)28(34)30-29-16-20-12-21(17-29)14-22(13-20)18-29/h5-10,15,19-22H,2-4,11-14,16-18H2,1H3,(H,30,34) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324634
(CHEMBL1215942 | N-(Adamantan-1-yl)-6-(furan-2-yl)-...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-c1ccco1 |TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:15:12:17.19.18,16:17:12:15.20.14| Show InChI InChI=1S/C29H34N2O3/c1-2-3-4-9-31-18-24(27(32)23-14-22(7-8-25(23)31)26-6-5-10-34-26)28(33)30-29-15-19-11-20(16-29)13-21(12-19)17-29/h5-8,10,14,18-21H,2-4,9,11-13,15-17H2,1H3,(H,30,33) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543739
(CHEMBL4647981)Show SMILES CCCCCCC(C)(C)c1cc(OC)cc(OCCCCCCCC(=O)NC2CC2)c1 Show InChI InChI=1S/C27H45NO3/c1-5-6-7-12-17-27(2,3)22-19-24(30-4)21-25(20-22)31-18-13-10-8-9-11-14-26(29)28-23-15-16-23/h19-21,23H,5-18H2,1-4H3,(H,28,29) | PDB
NCI pathway
Reactome pathway
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PC cid
PC sid
UniChem
| Article
PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543738
(CHEMBL4644215)Show InChI InChI=1S/C26H43NO3/c1-3-4-11-14-22-19-24(29-2)21-25(20-22)30-18-13-10-8-6-5-7-9-12-15-26(28)27-23-16-17-23/h19-21,23H,3-18H2,1-2H3,(H,27,28) | PDB
Reactome pathway
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| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| PDB
Article
PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
Reactome pathway
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| PDB
Article
PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324635
(4-Oxo-1-pentyl-6-thiophen-2-yl-1,4-dihydro-quinoli...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-c1cccs1 |TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:15:12:17.19.18,16:17:12:15.20.14| Show InChI InChI=1S/C29H34N2O2S/c1-2-3-4-9-31-18-24(27(32)23-14-22(7-8-25(23)31)26-6-5-10-34-26)28(33)30-29-15-19-11-20(16-29)13-21(12-19)17-29/h5-8,10,14,18-21H,2-4,9,11-13,15-17H2,1H3,(H,30,33) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324663
(6-(furan-2-yl)-4-oxo-1-pentyl-N-((1R,2R,4S)-1,3,3-...)Show SMILES CCCCCn1cc(C(=O)N[C@@H]2[C@]3(C)CC[C@@H](C3)C2(C)C)c(=O)c2cc(ccc12)-c1ccco1 |r| Show InChI InChI=1S/C29H36N2O3/c1-5-6-7-14-31-18-22(26(33)30-27-28(2,3)20-12-13-29(27,4)17-20)25(32)21-16-19(10-11-23(21)31)24-9-8-15-34-24/h8-11,15-16,18,20,27H,5-7,12-14,17H2,1-4H3,(H,30,33)/t20-,27-,29+/m0/s1 | PDB
Reactome pathway
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PC sid
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PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543753
(CHEMBL4644161)Show SMILES CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(OC(C)C)c1 Show InChI InChI=1S/C28H47NO3/c1-4-5-12-15-24-20-26(22-27(21-24)32-23(2)3)31-19-14-11-9-7-6-8-10-13-16-28(30)29-25-17-18-25/h20-23,25H,4-19H2,1-3H3,(H,29,30) | PDB
Reactome pathway
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| PC cid
PC sid
UniChem
| Article
PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50324658
(6-bromo-4-oxo-1-pentyl-N-((1R,2R,4S)-1,3,3-trimeth...)Show SMILES CCCCCn1cc(C(=O)N[C@H]2C(C)(C)[C@H]3CC[C@]2(C)C3)c(=O)c2cc(Br)ccc12 |r| Show InChI InChI=1S/C25H33BrN2O2/c1-5-6-7-12-28-15-19(21(29)18-13-17(26)8-9-20(18)28)22(30)27-23-24(2,3)16-10-11-25(23,4)14-16/h8-9,13,15-16,23H,5-7,10-12,14H2,1-4H3,(H,27,30)/t16-,23-,25+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50395751
(CHEMBL2164507)Show SMILES CCN1CCC(CC(=O)NC2(C(=O)Nc3cc(Cl)cc(Cl)c23)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C23H23Cl4N3O2/c1-2-30-7-5-13(6-8-30)9-20(31)29-23(14-3-4-16(25)17(26)10-14)21-18(27)11-15(24)12-19(21)28-22(23)32/h3-4,10-13H,2,5-9H2,1H3,(H,28,32)(H,29,31) | PDB
Reactome pathway
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| Article
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| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]-ghrelin from human GHSR1 expressed in CHO-CREluc cells after 1 hr by scintillation counting |
Bioorg Med Chem 20: 5623-36 (2012)
Article DOI: 10.1016/j.bmc.2012.07.018
BindingDB Entry DOI: 10.7270/Q2HD7WS4 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543738
(CHEMBL4644215)Show InChI InChI=1S/C26H43NO3/c1-3-4-11-14-22-19-24(29-2)21-25(20-22)30-18-13-10-8-6-5-7-9-12-15-26(28)27-23-16-17-23/h19-21,23H,3-18H2,1-2H3,(H,27,28) | PDB
NCI pathway
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
| Article
PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543756
(CHEMBL4646867)Show InChI InChI=1S/C25H41NO2/c1-2-3-10-14-22-15-13-16-24(21-22)28-20-12-9-7-5-4-6-8-11-17-25(27)26-23-18-19-23/h13,15-16,21,23H,2-12,14,17-20H2,1H3,(H,26,27) | PDB
Reactome pathway
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| Article
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| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543739
(CHEMBL4647981)Show SMILES CCCCCCC(C)(C)c1cc(OC)cc(OCCCCCCCC(=O)NC2CC2)c1 Show InChI InChI=1S/C27H45NO3/c1-5-6-7-12-17-27(2,3)22-19-24(30-4)21-25(20-22)31-18-13-10-8-9-11-14-26(29)28-23-15-16-23/h19-21,23H,5-18H2,1-4H3,(H,28,29) | PDB
Reactome pathway
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| Article
PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324636
(6-(4-Hydroxy-phenyl)-4-oxo-1-pentyl-1,4-dihydro-qu...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-c1ccc(O)cc1 |TLB:18:17:20:13.12.14,18:13:20:17.19.16,14:15:19:13.12.18,THB:14:13:19:15.20.16| Show InChI InChI=1S/C31H36N2O3/c1-2-3-4-11-33-19-27(30(36)32-31-16-20-12-21(17-31)14-22(13-20)18-31)29(35)26-15-24(7-10-28(26)33)23-5-8-25(34)9-6-23/h5-10,15,19-22,34H,2-4,11-14,16-18H2,1H3,(H,32,36) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324662
(1-But-3-enyl-6-furan-2-yl-4-oxo-1,4-dihydro-quinol...)Show SMILES C=CCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-c1ccco1 |TLB:13:14:18:12.11.17,THB:13:12:18:14.19.15,15:14:11:16.18.17,15:16:11:14.19.13| Show InChI InChI=1S/C28H30N2O3/c1-2-3-8-30-17-23(26(31)22-13-21(6-7-24(22)30)25-5-4-9-33-25)27(32)29-28-14-18-10-19(15-28)12-20(11-18)16-28/h2,4-7,9,13,17-20H,1,3,8,10-12,14-16H2,(H,29,32) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543755
(CHEMBL4638147)Show SMILES CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(OCC=C)c1 Show InChI InChI=1S/C28H45NO3/c1-3-5-12-15-24-21-26(31-19-4-2)23-27(22-24)32-20-14-11-9-7-6-8-10-13-16-28(30)29-25-17-18-25/h4,21-23,25H,2-3,5-20H2,1H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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| PC cid
PC sid
UniChem
| Article
PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324658
(6-bromo-4-oxo-1-pentyl-N-((1R,2R,4S)-1,3,3-trimeth...)Show SMILES CCCCCn1cc(C(=O)N[C@H]2C(C)(C)[C@H]3CC[C@]2(C)C3)c(=O)c2cc(Br)ccc12 |r| Show InChI InChI=1S/C25H33BrN2O2/c1-5-6-7-12-28-15-19(21(29)18-13-17(26)8-9-20(18)28)22(30)27-23-24(2,3)16-10-11-25(23,4)14-16/h8-9,13,15-16,23H,5-7,10-12,14H2,1-4H3,(H,27,30)/t16-,23-,25+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50176951
(11-(3-hydroxy-5-pentylphenoxy)undecanoic acid cycl...)Show InChI InChI=1S/C25H41NO3/c1-2-3-10-13-21-18-23(27)20-24(19-21)29-17-12-9-7-5-4-6-8-11-14-25(28)26-22-15-16-22/h18-20,22,27H,2-17H2,1H3,(H,26,28) | PDB
NCI pathway
Reactome pathway
KEGG
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CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50180022
(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1 |THB:21:22:26.25:28| Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543756
(CHEMBL4646867)Show InChI InChI=1S/C25H41NO2/c1-2-3-10-14-22-15-13-16-24(21-22)28-20-12-9-7-5-4-6-8-11-17-25(27)26-23-18-19-23/h13,15-16,21,23H,2-12,14,17-20H2,1H3,(H,26,27) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50272388
(6-Isopropyl-4-oxo-1-pentyl-1,4-dihydro-quinoline-3...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)C(C)C |TLB:10:11:14:18.16.17,THB:16:15:12:18.17.19,16:17:14.15.20:12,19:17:14:20.11.12,19:11:14:18.16.17| Show InChI InChI=1S/C28H38N2O2/c1-4-5-6-9-30-17-24(26(31)23-13-22(18(2)3)7-8-25(23)30)27(32)29-28-14-19-10-20(15-28)12-21(11-19)16-28/h7-8,13,17-21H,4-6,9-12,14-16H2,1-3H3,(H,29,32) | PDB
Reactome pathway
KEGG
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543752
(CHEMBL4640400)Show InChI InChI=1S/C27H45NO3/c1-3-5-12-15-23-20-25(30-4-2)22-26(21-23)31-19-14-11-9-7-6-8-10-13-16-27(29)28-24-17-18-24/h20-22,24H,3-19H2,1-2H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543745
(CHEMBL4638446)Show InChI InChI=1S/C26H43NO3/c1-4-6-13-16-23-20-24(29-3)22-25(21-23)30-19-15-12-10-8-7-9-11-14-17-26(28)27-18-5-2/h5,20-22H,2,4,6-19H2,1,3H3,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50055267
(CHEMBL3323682)Show SMILES CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCC(=O)NCC=C)c1 Show InChI InChI=1S/C26H43NO3/c1-5-7-8-13-16-26(3,4)22-19-23(28)21-24(20-22)30-18-14-11-9-10-12-15-25(29)27-17-6-2/h6,19-21,28H,2,5,7-18H2,1,3-4H3,(H,27,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324654
(6-Cyclohexyl-4-oxo-1-pentyl-1,4-dihydro-quinoline-...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)C1CCCCC1 |TLB:18:13:20:17.19.16,18:17:20:13.12.14,THB:16:15:12:17.19.18,16:17:12:15.20.14| Show InChI InChI=1S/C31H42N2O2/c1-2-3-7-12-33-20-27(30(35)32-31-17-21-13-22(18-31)15-23(14-21)19-31)29(34)26-16-25(10-11-28(26)33)24-8-5-4-6-9-24/h10-11,16,20-24H,2-9,12-15,17-19H2,1H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50055267
(CHEMBL3323682)Show SMILES CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCC(=O)NCC=C)c1 Show InChI InChI=1S/C26H43NO3/c1-5-7-8-13-16-26(3,4)22-19-23(28)21-24(20-22)30-18-14-11-9-10-12-15-25(29)27-17-6-2/h6,19-21,28H,2,5,7-18H2,1,3-4H3,(H,27,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543746
(CHEMBL4639040)Show SMILES CCCCCCC(C)(C)c1cc(OC)cc(OCCCCCCCC(=O)NCC=C)c1 Show InChI InChI=1S/C27H45NO3/c1-6-8-9-14-17-27(3,4)23-20-24(30-5)22-25(21-23)31-19-15-12-10-11-13-16-26(29)28-18-7-2/h7,20-22H,2,6,8-19H2,1,3-5H3,(H,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324653
(CHEMBL1215963 | N-(Adamantan-1-yl)-6-(1H-imidazol-...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-n1ccnc1 |TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:17:12:15.20.14,16:15:12:17.19.18| Show InChI InChI=1S/C28H34N4O2/c1-2-3-4-8-31-17-24(26(33)23-13-22(5-6-25(23)31)32-9-7-29-18-32)27(34)30-28-14-19-10-20(15-28)12-21(11-19)16-28/h5-7,9,13,17-21H,2-4,8,10-12,14-16H2,1H3,(H,30,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Growth hormone secretagogue receptor type 1
(Homo sapiens (Human)) | BDBM50395753
(CHEMBL2164499)Show SMILES CCN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)cc(Cl)c23)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C22H22Cl4N4O2/c1-2-29-5-7-30(8-6-29)12-19(31)28-22(13-3-4-15(24)16(25)9-13)20-17(26)10-14(23)11-18(20)27-21(22)32/h3-4,9-11H,2,5-8,12H2,1H3,(H,27,32)(H,28,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Research
Curated by ChEMBL
| Assay Description
Displacement of [125I]-ghrelin from human GHSR1 expressed in CHO-CREluc cells after 1 hr by scintillation counting |
Bioorg Med Chem 20: 5623-36 (2012)
Article DOI: 10.1016/j.bmc.2012.07.018
BindingDB Entry DOI: 10.7270/Q2HD7WS4 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324637
(6-Cyclohex-1-enyl-4-oxo-1-pentyl-1,4-dihydro-quino...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)C1=CCCCC1 |t:34,TLB:14:15:19:13.12.18,THB:14:13:19:15.20.16,16:17:12:15.20.14,16:15:12:17.19.18| Show InChI InChI=1S/C31H40N2O2/c1-2-3-7-12-33-20-27(30(35)32-31-17-21-13-22(18-31)15-23(14-21)19-31)29(34)26-16-25(10-11-28(26)33)24-8-5-4-6-9-24/h8,10-11,16,20-23H,2-7,9,12-15,17-19H2,1H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324650
(CHEMBL1215888 | N-(Adamantan-1-yl)-6-ethynyl-4-oxo...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)C#C |TLB:18:13:20:17.19.16,18:17:20:13.12.14,14:15:19:13.12.18,THB:14:13:19:15.20.16| Show InChI InChI=1S/C27H32N2O2/c1-3-5-6-9-29-17-23(25(30)22-13-18(4-2)7-8-24(22)29)26(31)28-27-14-19-10-20(15-27)12-21(11-19)16-27/h2,7-8,13,17,19-21H,3,5-6,9-12,14-16H2,1H3,(H,28,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50543741
(CHEMBL4644130)Show InChI InChI=1S/C27H45NO3/c1-3-4-11-14-24-19-25(30-2)21-26(20-24)31-18-13-10-8-6-5-7-9-12-15-27(29)28-22-23-16-17-23/h19-21,23H,3-18,22H2,1-2H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324638
(6-(4-Chloro-phenyl)-4-oxo-1-pentyl-1,4-dihydro-qui...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-c1ccc(Cl)cc1 |TLB:18:17:20:13.12.14,18:13:20:17.19.16,14:15:19:13.12.18,THB:14:13:19:15.20.16| Show InChI InChI=1S/C31H35ClN2O2/c1-2-3-4-11-34-19-27(30(36)33-31-16-20-12-21(17-31)14-22(13-20)18-31)29(35)26-15-24(7-10-28(26)34)23-5-8-25(32)9-6-23/h5-10,15,19-22H,2-4,11-14,16-18H2,1H3,(H,33,36) | PDB
Reactome pathway
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PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543754
(CHEMBL4648254)Show SMILES CCCCCc1cc(OCCCC)cc(OCCCCCCCCCCC(=O)NC2CC2)c1 Show InChI InChI=1S/C29H49NO3/c1-3-5-13-16-25-22-27(32-20-6-4-2)24-28(23-25)33-21-15-12-10-8-7-9-11-14-17-29(31)30-26-18-19-26/h22-24,26H,3-21H2,1-2H3,(H,30,31) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM21278
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30) | PDB
NCI pathway
Reactome pathway
KEGG
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CHEMBL
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UniChem
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| DrugBank
Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543752
(CHEMBL4640400)Show InChI InChI=1S/C27H45NO3/c1-3-5-12-15-23-20-25(30-4-2)22-26(21-23)31-19-14-11-9-7-6-8-10-13-16-27(29)28-24-17-18-24/h20-22,24H,3-19H2,1-2H3,(H,28,29) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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| PC cid
PC sid
UniChem
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50055463
(CHEMBL3323672)Show SMILES CCCCCc1cc(O)cc(OCCCCCCCC(=O)N[C@H](C)CO)c1 |r| Show InChI InChI=1S/C22H37NO4/c1-3-4-8-11-19-14-20(25)16-21(15-19)27-13-10-7-5-6-9-12-22(26)23-18(2)17-24/h14-16,18,24-25H,3-13,17H2,1-2H3,(H,23,26)/t18-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50176951
(11-(3-hydroxy-5-pentylphenoxy)undecanoic acid cycl...)Show InChI InChI=1S/C25H41NO3/c1-2-3-10-13-21-18-23(27)20-24(19-21)29-17-12-9-7-5-4-6-8-11-14-25(28)26-22-15-16-22/h18-20,22,27H,2-17H2,1H3,(H,26,28) | PDB
Reactome pathway
KEGG
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CHEMBL
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| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543755
(CHEMBL4638147)Show SMILES CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(OCC=C)c1 Show InChI InChI=1S/C28H45NO3/c1-3-5-12-15-24-21-26(31-19-4-2)23-27(22-24)32-20-14-11-9-7-6-8-10-13-16-28(30)29-25-17-18-25/h4,21-23,25H,2-3,5-20H2,1H3,(H,29,30) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324639
(6-(2,4-Difluoro-phenyl)-4-oxo-1-pentyl-1,4-dihydro...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(ccc12)-c1ccc(F)cc1F |TLB:14:15:19:13.12.18,18:13:20:17.19.16,18:17:20:13.12.14,THB:14:13:19:15.20.16| Show InChI InChI=1S/C31H34F2N2O2/c1-2-3-4-9-35-18-26(30(37)34-31-15-19-10-20(16-31)12-21(11-19)17-31)29(36)25-13-22(5-8-28(25)35)24-7-6-23(32)14-27(24)33/h5-8,13-14,18-21H,2-4,9-12,15-17H2,1H3,(H,34,37) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50055453
(CHEMBL3323681)Show InChI InChI=1S/C25H41NO3/c1-3-5-12-15-22-19-23(27)21-24(20-22)29-18-14-11-9-7-6-8-10-13-16-25(28)26-17-4-2/h4,19-21,27H,2-3,5-18H2,1H3,(H,26,28) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324655
(CHEMBL1215976 | N-(Adamantan-1-yl)-6-ethyl-4-oxo-1...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(CC)ccc12 |TLB:14:15:19:13.12.18,18:13:20:17.19.16,18:17:20:13.12.14,THB:14:13:19:15.20.16| Show InChI InChI=1S/C27H36N2O2/c1-3-5-6-9-29-17-23(25(30)22-13-18(4-2)7-8-24(22)29)26(31)28-27-14-19-10-20(15-27)12-21(11-19)16-27/h7-8,13,17,19-21H,3-6,9-12,14-16H2,1-2H3,(H,28,31) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 16.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50055461
(CHEMBL3323674)Show SMILES CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCC(=O)N[C@H](C)CO)c1 |r| Show InChI InChI=1S/C26H45NO4/c1-5-6-7-12-15-26(3,4)22-17-23(29)19-24(18-22)31-16-13-10-8-9-11-14-25(30)27-21(2)20-28/h17-19,21,28-29H,5-16,20H2,1-4H3,(H,27,30)/t21-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
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PC sid
UniChem
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PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50324630
(6-Iodo-4-oxo-1-pentyl-1,4-dihydro-quinoline-3-carb...)Show SMILES CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(I)ccc12 |TLB:14:15:19:13.12.18,18:13:20:17.19.16,18:17:20:13.12.14,THB:14:13:19:15.20.16| Show InChI InChI=1S/C25H31IN2O2/c1-2-3-4-7-28-15-21(23(29)20-11-19(26)5-6-22(20)28)24(30)27-25-12-16-8-17(13-25)10-18(9-16)14-25/h5-6,11,15-18H,2-4,7-10,12-14H2,1H3,(H,27,30) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human CB2 receptor expressed in HEK cells |
J Med Chem 53: 5915-28 (2010)
Article DOI: 10.1021/jm100123x
BindingDB Entry DOI: 10.7270/Q2PC33BG |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
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CHEMBL
MCE
PC cid
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| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50543753
(CHEMBL4644161)Show SMILES CCCCCc1cc(OCCCCCCCCCCC(=O)NC2CC2)cc(OC(C)C)c1 Show InChI InChI=1S/C28H47NO3/c1-4-5-12-15-24-20-26(22-27(21-24)32-23(2)3)31-19-14-11-9-7-6-8-10-13-16-28(30)29-25-17-18-25/h20-23,25H,4-19H2,1-3H3,(H,29,30) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membrane |
Bioorg Med Chem 28: (2020)
Article DOI: 10.1016/j.bmc.2020.115513
BindingDB Entry DOI: 10.7270/Q2R49VB2 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50055460
(CHEMBL3323675)Show SMILES CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCCCCC(=O)N[C@H](C)CO)c1 |r| Show InChI InChI=1S/C29H51NO4/c1-5-6-7-15-18-29(3,4)25-20-26(32)22-27(21-25)34-19-16-13-11-9-8-10-12-14-17-28(33)30-24(2)23-31/h20-22,24,31-32H,5-19,23H2,1-4H3,(H,30,33)/t24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cell membranes |
Bioorg Med Chem 22: 4770-83 (2014)
Article DOI: 10.1016/j.bmc.2014.07.006
BindingDB Entry DOI: 10.7270/Q2TH8PCG |
More data for this
Ligand-Target Pair | |
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