Compile Data Set for Download or QSAR

Found 609 hits with Last Name = 'motoyaji' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359651 (CHEMBL1929041) Show SMILES Cc1cc(F)ccc1-n1nc(cc1-c1cc(Cl)c2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H12ClF4N3O2/c1-9-4-11(21)2-3-14(9)27-15(7-16(26-27)19(22,23)24)10-5-12(20)18-13(6-10)25-17(28)8-29-18/h2-7H,8H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359652 (CHEMBL1929042) Show SMILES Cc1cc(cc2NC(=O)COc12)-c1cc(nn1-c1ccc(F)cc1C)C(F)(F)F Show InChI InChI=1S/C20H15F4N3O2/c1-10-6-13(21)3-4-15(10)27-16(8-17(26-27)20(22,23)24)12-5-11(2)19-14(7-12)25-18(28)9-29-19/h3-8H,9H2,1-2H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human MR transfected in human COS1 cells after 1 day by luciferase reporter gene assay				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359652 (CHEMBL1929042) Show SMILES Cc1cc(cc2NC(=O)COc12)-c1cc(nn1-c1ccc(F)cc1C)C(F)(F)F Show InChI InChI=1S/C20H15F4N3O2/c1-10-6-13(21)3-4-15(10)27-16(8-17(26-27)20(22,23)24)12-5-11(2)19-14(7-12)25-18(28)9-29-19/h3-8H,9H2,1-2H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359644 (CHEMBL1928877) Show SMILES O=C1COc2ccc(cc2N1)C1=Nn2ccnc2SC1c1ccccc1 |t:13| Show InChI InChI=1S/C19H14N4O2S/c24-16-11-25-15-7-6-13(10-14(15)21-16)17-18(12-4-2-1-3-5-12)26-19-20-8-9-23(19)22-17/h1-10,18H,11H2,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359649 (CHEMBL1929039) Show SMILES Cc1cc(F)ccc1-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H13F4N3O2/c1-10-6-12(20)3-4-14(10)26-15(8-17(25-26)19(21,22)23)11-2-5-16-13(7-11)24-18(27)9-28-16/h2-8H,9H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359649 (CHEMBL1929039) Show SMILES Cc1cc(F)ccc1-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H13F4N3O2/c1-10-6-12(20)3-4-14(10)26-15(8-17(25-26)19(21,22)23)11-2-5-16-13(7-11)24-18(27)9-28-16/h2-8H,9H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human MR transfected in human COS1 cells after 1 day by luciferase reporter gene assay				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50228080 (2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrof...) Show SMILES CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12 |r,t:6| Show InChI InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50228080 (2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrof...) Show SMILES CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12 |r,t:6| Show InChI InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human MR transfected in human COS1 cells after 1 day by luciferase reporter gene assay				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359645 (CHEMBL1928878) Show SMILES O=C1COc2ccc(cc2N1)C1=Nc2ccccc2SC1c1ccccc1 |t:13| Show InChI InChI=1S/C22H16N2O2S/c25-20-13-26-18-11-10-15(12-17(18)23-20)21-22(14-6-2-1-3-7-14)27-19-9-5-4-8-16(19)24-21/h1-12,22H,13H2,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359651 (CHEMBL1929041) Show SMILES Cc1cc(F)ccc1-n1nc(cc1-c1cc(Cl)c2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H12ClF4N3O2/c1-9-4-11(21)2-3-14(9)27-15(7-16(26-27)19(22,23)24)10-5-12(20)18-13(6-10)25-17(28)8-29-18/h2-7H,8H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human MR transfected in human COS1 cells after 1 day by luciferase reporter gene assay				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359650 (CHEMBL1929040) Show SMILES Cc1cc(F)ccc1-n1nc(cc1-c1cc(F)c2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H12F5N3O2/c1-9-4-11(20)2-3-14(9)27-15(7-16(26-27)19(22,23)24)10-5-12(21)18-13(6-10)25-17(28)8-29-18/h2-7H,8H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359648 (CHEMBL1929036) Show SMILES Cc1ccccc1-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H14F3N3O2/c1-11-4-2-3-5-14(11)25-15(9-17(24-25)19(20,21)22)12-6-7-16-13(8-12)23-18(26)10-27-16/h2-9H,10H2,1H3,(H,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation counting				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50359650 (CHEMBL1929040) Show SMILES Cc1cc(F)ccc1-n1nc(cc1-c1cc(F)c2OCC(=O)Nc2c1)C(F)(F)F Show InChI InChI=1S/C19H12F5N3O2/c1-9-4-11(20)2-3-14(9)27-15(7-16(26-27)19(22,23)24)10-5-12(21)18-13(6-10)25-17(28)8-29-18/h2-7H,8H2,1H3,(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human MR transfected in human COS1 cells after 1 day by luciferase reporter gene assay				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50359644 (CHEMBL1928877) Show SMILES O=C1COc2ccc(cc2N1)C1=Nn2ccnc2SC1c1ccccc1 |t:13| Show InChI InChI=1S/C19H14N4O2S/c24-16-11-25-15-7-6-13(10-14(15)21-16)17-18(12-4-2-1-3-5-12)26-19-20-8-9-23(19)22-17/h1-10,18H,11H2,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]testosterone from AR				J Med Chem 54: 8616-31 (2011) Article DOI: 10.1021/jm2011645 BindingDB Entry DOI: 10.7270/Q21G0MP5
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306349 (US10144742, Compound I-511) Show SMILES COc1cccc(c1)-c1nc2cc(ccc2nc1OC(C)C)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H27N5O3/c1-16(2)33-25-23(17-6-4-7-19(14-17)32-3)29-21-15-18(9-10-20(21)30-25)24(31)28-11-5-8-22-26-12-13-27-22/h4,6-7,9-10,12-16H,5,8,11H2,1-3H3,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306350 (US10144742, Compound I-512) Show SMILES COc1cc(F)cc(c1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H23F2N5O2/c1-37-22-14-19(13-21(30)16-22)27-26(17-4-7-20(29)8-5-17)34-23-9-6-18(15-24(23)35-27)28(36)33-10-2-3-25-31-11-12-32-25/h4-9,11-16H,2-3,10H2,1H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306351 (US10144742, Compound I-513) Show SMILES CN1CCC(COc2nc3ccc(cc3nc2-c2ccc(F)cc2)C(=O)NCCCc2ncc[nH]2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306352 (US10144742, Compound I-514) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CCNCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C26H27FN6O2/c27-19-6-3-17(4-7-19)24-26(35-20-9-12-28-13-10-20)33-21-8-5-18(16-22(21)32-24)25(34)31-11-1-2-23-29-14-15-30-23/h3-8,14-16,20,28H,1-2,9-13H2,(H,29,30)(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306354 (US10144742, Compound I-516) Show SMILES COc1cc(c(F)cn1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCc1nc2cnccc2[nH]1 Show InChI InChI=1S/C28H19F2N7O2/c1-39-25-11-18(19(30)12-32-25)27-26(15-2-5-17(29)6-3-15)36-20-7-4-16(10-22(20)37-27)28(38)33-14-24-34-21-8-9-31-13-23(21)35-24/h2-13H,14H2,1H3,(H,33,38)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306357 (US10144742, Compound I-519) Show SMILES COc1cc(c(F)cn1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1nccn1C Show InChI InChI=1S/C28H24F2N6O2/c1-36-13-12-31-24(36)4-3-11-32-28(37)18-7-10-22-23(14-18)35-27(20-15-25(38-2)33-16-21(20)30)26(34-22)17-5-8-19(29)9-6-17/h5-10,12-16H,3-4,11H2,1-2H3,(H,32,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306358 (US10144742, Compound I-520) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cc(Cl)ccc1F)C(=O)NCCCc1nnc[nH]1 Show InChI InChI=1S/C26H19ClF2N6O/c27-17-6-9-20(29)19(13-17)25-24(15-3-7-18(28)8-4-15)33-21-10-5-16(12-22(21)34-25)26(36)30-11-1-2-23-31-14-32-35-23/h3-10,12-14H,1-2,11H2,(H,30,36)(H,31,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM305985 (US10144742, Compound I-147) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1N1CCOCC1)C(=O)NCc1ccc2nccn2c1 Show InChI InChI=1S/C27H23FN6O2/c28-21-5-2-19(3-6-21)25-26(33-11-13-36-14-12-33)32-22-7-4-20(15-23(22)31-25)27(35)30-16-18-1-8-24-29-9-10-34(24)17-18/h1-10,15,17H,11-14,16H2,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306021 (US10144742, Compound I-183) Show SMILES COc1cccc(c1)-c1nc2cc(ccc2nc1N1CCCCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H30N6O2/c1-35-21-8-5-7-19(17-21)25-26(33-15-3-2-4-16-33)32-22-11-10-20(18-23(22)31-25)27(34)30-12-6-9-24-28-13-14-29-24/h5,7-8,10-11,13-14,17-18H,2-4,6,9,12,15-16H2,1H3,(H,28,29)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306093 (US10144742, Compound I-255) Show SMILES Clc1ccc(cc1)-c1nc2cc(ccc2nc1N1CCC(CC1)N1CCOCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C30H34ClN7O2/c31-23-6-3-21(4-7-23)28-29(38-14-9-24(10-15-38)37-16-18-40-19-17-37)36-25-8-5-22(20-26(25)35-28)30(39)34-11-1-2-27-32-12-13-33-27/h3-8,12-13,20,24H,1-2,9-11,14-19H2,(H,32,33)(H,34,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306113 (US10144742, Compound I-275) Show SMILES O=C(NCCCn1ccnc1)c1ccc2nc(N3CCC4(CC3)OCCO4)c(nc2c1)-c1ccccc1 Show InChI InChI=1S/C28H30N6O3/c35-27(30-11-4-13-33-16-12-29-20-33)22-7-8-23-24(19-22)31-25(21-5-2-1-3-6-21)26(32-23)34-14-9-28(10-15-34)36-17-18-37-28/h1-3,5-8,12,16,19-20H,4,9-11,13-15,17-18H2,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306207 (US10144742, Compound I-369) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1ccc(Cl)c(c1)C(F)(F)F)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H20ClF4N5O/c29-21-9-5-17(14-20(21)28(31,32)33)26-25(16-3-7-19(30)8-4-16)37-22-10-6-18(15-23(22)38-26)27(39)36-11-1-2-24-34-12-13-35-24/h3-10,12-15H,1-2,11H2,(H,34,35)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306231 (US10144742, Compound I-393) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cc(ccc1Cl)C#N)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H20ClFN6O/c29-22-9-3-17(16-31)14-21(22)27-26(18-4-7-20(30)8-5-18)35-23-10-6-19(15-24(23)36-27)28(37)34-11-1-2-25-32-12-13-33-25/h3-10,12-15H,1-2,11H2,(H,32,33)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306234 (US10144742, Compound I-396) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1ccccn1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H23FN6O2/c28-20-9-6-18(7-10-20)25-27(36-17-21-4-1-2-12-29-21)34-22-11-8-19(16-23(22)33-25)26(35)32-13-3-5-24-30-14-15-31-24/h1-2,4,6-12,14-16H,3,5,13,17H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306235 (US10144742, Compound I-397) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1ccc(Cl)c(Cl)c1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H20Cl2FN5O/c28-20-9-5-17(14-21(20)29)26-25(16-3-7-19(30)8-4-16)34-22-10-6-18(15-23(22)35-26)27(36)33-11-1-2-24-31-12-13-32-24/h3-10,12-15H,1-2,11H2,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306236 (US10144742, Compound I-398) Show SMILES COc1cccc(c1F)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H23F2N5O2/c1-37-23-5-2-4-20(25(23)30)27-26(17-7-10-19(29)11-8-17)34-21-12-9-18(16-22(21)35-27)28(36)33-13-3-6-24-31-14-15-32-24/h2,4-5,7-12,14-16H,3,6,13H2,1H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306237 (US10144742, Compound I-399) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cc(F)ccc1Cl)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H20ClF2N5O/c28-21-9-8-19(30)15-20(21)26-25(16-3-6-18(29)7-4-16)34-22-10-5-17(14-23(22)35-26)27(36)33-11-1-2-24-31-12-13-32-24/h3-10,12-15H,1-2,11H2,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306238 (US10144742, Compound I-400) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CCCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C26H26FN5O2/c27-19-10-7-17(8-11-19)24-26(34-20-4-1-2-5-20)32-21-12-9-18(16-22(21)31-24)25(33)30-13-3-6-23-28-14-15-29-23/h7-12,14-16,20H,1-6,13H2,(H,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306240 (US10144742, Compound I-402) Show SMILES CCOc1nc2ccc(cc2nc1-c1ccc(Cl)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C23H22ClN5O2/c1-2-31-23-21(15-5-8-17(24)9-6-15)28-19-14-16(7-10-18(19)29-23)22(30)27-11-3-4-20-25-12-13-26-20/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306242 (US10144742, Compound I-404) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CC2(CCN2)C1)C(=O)NCCCc1ncc[nH]1 |(10.52,5.64,;9.19,4.87,;9.19,3.33,;7.85,2.56,;6.52,3.33,;6.52,4.87,;7.85,5.64,;5.19,2.56,;3.85,3.33,;2.52,2.56,;1.18,3.33,;-.15,2.56,;-.15,1.02,;1.18,.25,;2.52,1.02,;3.85,.25,;5.19,1.02,;6.52,.25,;6.52,-1.29,;5.43,-2.38,;6.52,-3.46,;5.43,-4.55,;6.52,-5.64,;7.61,-4.55,;7.61,-2.38,;-1.48,3.33,;-1.48,4.87,;-2.82,2.56,;-4.15,3.33,;-5.48,2.56,;-6.82,3.33,;-8.15,2.56,;-9.62,3.04,;-10.52,1.79,;-9.62,.55,;-8.15,1.02,)| Show InChI InChI=1S/C27H27FN6O2/c28-19-6-3-17(4-7-19)24-26(36-20-15-27(16-20)9-11-32-27)34-21-8-5-18(14-22(21)33-24)25(35)31-10-1-2-23-29-12-13-30-23/h3-8,12-14,20,32H,1-2,9-11,15-16H2,(H,29,30)(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306244 (US10144742, Compound I-406) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1CCOCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H28FN5O3/c28-21-6-3-19(4-7-21)25-27(36-17-18-9-14-35-15-10-18)33-22-8-5-20(16-23(22)32-25)26(34)31-11-1-2-24-29-12-13-30-24/h3-8,12-13,16,18H,1-2,9-11,14-15,17H2,(H,29,30)(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306245 (US10144742, Compound I-407) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1(CCC1)[N+]#[C-])C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H25FN6O2/c1-29-27(11-3-12-27)17-36-26-24(18-5-8-20(28)9-6-18)33-22-16-19(7-10-21(22)34-26)25(35)32-13-2-4-23-30-14-15-31-23/h5-10,14-16H,2-4,11-13,17H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306247 (US10144742, Compound I-409) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1cccnc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H23FN6O2/c28-21-8-5-19(6-9-21)25-27(36-17-18-3-1-11-29-16-18)34-22-10-7-20(15-23(22)33-25)26(35)32-12-2-4-24-30-13-14-31-24/h1,3,5-11,13-16H,2,4,12,17H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306252 (US10144742, Compound I-414) Show SMILES CC(C)Oc1nc2ccc(cc2nc1-c1cc(ccc1F)C#N)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H23FN6O2/c1-15(2)34-25-23(18-12-16(14-27)5-7-19(18)26)31-21-13-17(6-8-20(21)32-25)24(33)30-9-3-4-22-28-10-11-29-22/h5-8,10-13,15H,3-4,9H2,1-2H3,(H,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306258 (US10144742, Compound I-420) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCCc1ccccc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C29H26FN5O2/c30-23-11-8-21(9-12-23)27-29(37-18-14-20-5-2-1-3-6-20)35-24-13-10-22(19-25(24)34-27)28(36)33-15-4-7-26-31-16-17-32-26/h1-3,5-6,8-13,16-17,19H,4,7,14-15,18H2,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306260 (US10144742, Compound I-422) Show SMILES Cc1cc(c(C)s1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H24FN5OS/c1-16-14-21(17(2)35-16)26-25(18-5-8-20(28)9-6-18)32-22-10-7-19(15-23(22)33-26)27(34)31-11-3-4-24-29-12-13-30-24/h5-10,12-15H,3-4,11H2,1-2H3,(H,29,30)(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306264 (US10144742, Compound I-426) Show SMILES COc1cc(ccc1F)-c1nc2cc(ccc2nc1OC(C)C)C(=O)NCc1ccc2nccn2c1 Show InChI InChI=1S/C27H24FN5O3/c1-16(2)36-27-25(18-5-7-20(28)23(13-18)35-3)31-22-12-19(6-8-21(22)32-27)26(34)30-14-17-4-9-24-29-10-11-33(24)15-17/h4-13,15-16H,14H2,1-3H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306265 (US10144742, Compound I-427) Show SMILES COC1CC(C1)Oc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 |(7.85,-5.71,;6.52,-4.94,;6.52,-3.4,;5.43,-2.31,;6.52,-1.22,;7.61,-2.31,;6.52,.32,;5.19,1.09,;3.85,.32,;2.52,1.09,;1.18,.32,;-.15,1.09,;-.15,2.63,;1.18,3.4,;2.52,2.63,;3.85,3.4,;5.19,2.63,;6.52,3.4,;7.85,2.63,;9.19,3.4,;9.19,4.94,;10.52,5.71,;7.85,5.71,;6.52,4.94,;-1.48,3.4,;-1.48,4.94,;-2.82,2.63,;-4.15,3.4,;-5.48,2.63,;-6.82,3.4,;-8.15,2.63,;-8.15,1.09,;-9.62,.61,;-10.52,1.86,;-9.62,3.1,)| Show InChI InChI=1S/C26H26FN5O3/c1-34-19-14-20(15-19)35-26-24(16-4-7-18(27)8-5-16)31-22-13-17(6-9-21(22)32-26)25(33)30-10-2-3-23-28-11-12-29-23/h4-9,11-13,19-20H,2-3,10,14-15H2,1H3,(H,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306268 (US10144742, Compound I-430) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CCCNC1)C(=O)NCCCc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306273 (US10144742, Compound I-435) Show SMILES CC(C)Oc1nc2ccc(cc2nc1-c1ccc(F)c(Cl)c1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C24H23ClFN5O2/c1-14(2)33-24-22(15-5-7-18(26)17(25)12-15)30-20-13-16(6-8-19(20)31-24)23(32)29-9-3-4-21-27-10-11-28-21/h5-8,10-14H,3-4,9H2,1-2H3,(H,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306276 (US10144742, Compound I-438) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1CCCO1)C(=O)NCCCc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306277 (US10144742, Compound I-439) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1ccccc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H24FN5O2/c29-22-11-8-20(9-12-22)26-28(36-18-19-5-2-1-3-6-19)34-23-13-10-21(17-24(23)33-26)27(35)32-14-4-7-25-30-15-16-31-25/h1-3,5-6,8-13,15-17H,4,7,14,18H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306278 (US10144742, Compound I-440) Show SMILES CCOc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C23H22FN5O2/c1-2-31-23-21(15-5-8-17(24)9-6-15)28-19-14-16(7-10-18(19)29-23)22(30)27-11-3-4-20-25-12-13-26-20/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306280 (US10144742, Compound I-442) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCCc1cn[nH]c1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C26H24FN7O2/c27-20-6-3-18(4-7-20)24-26(36-13-9-17-15-31-32-16-17)34-21-8-5-19(14-22(21)33-24)25(35)30-10-1-2-23-28-11-12-29-23/h3-8,11-12,14-16H,1-2,9-10,13H2,(H,28,29)(H,30,35)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306283 (US10144742, Compound I-445) Show SMILES Cc1ccc(cc1-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1)C(F)(F)F Show InChI InChI=1S/C29H23F4N5O/c1-17-4-8-20(29(31,32)33)16-22(17)27-26(18-5-9-21(30)10-6-18)37-23-11-7-19(15-24(23)38-27)28(39)36-12-2-3-25-34-13-14-35-25/h4-11,13-16H,2-3,12H2,1H3,(H,34,35)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306284 (US10144742, Compound I-446) Show SMILES Cc1noc(C)c1COc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H25FN6O3/c1-16-21(17(2)37-34-16)15-36-27-25(18-5-8-20(28)9-6-18)32-23-14-19(7-10-22(23)33-27)26(35)31-11-3-4-24-29-12-13-30-24/h5-10,12-14H,3-4,11,15H2,1-2H3,(H,29,30)(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair

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