Found 21 hits with Last Name = 'schaller' and Initial = 'th' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM92901
(ADMA, 3)Show InChI InChI=1S/C8H18N4O2/c1-12(2)8(10)11-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14)/t6-/m0/s1 | PDB MMDB
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Similars
| Article PubMed
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50072297
((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...)Show InChI InChI=1S/C7H15N3O2/c1-5(8)10-4-2-3-6(9)7(11)12/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12)/t6-/m0/s1 | PDB MMDB
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| Article PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50254450
((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)Show InChI InChI=1S/C8H17N3O2/c1-2-7(10)11-5-3-4-6(9)8(12)13/h6H,2-5,9H2,1H3,(H2,10,11)(H,12,13)/t6-/m0/s1 | PDB MMDB
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| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92904
(nNOS and DDAH inhibitor, 14)Show InChI InChI=1S/C10H21N3O2/c1-2-3-6-9(12)13-7-4-5-8(11)10(14)15/h8H,2-7,11H2,1H3,(H2,12,13)(H,14,15)/t8-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| MMDB Article PubMed
| 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM92904
(nNOS and DDAH inhibitor, 14)Show InChI InChI=1S/C10H21N3O2/c1-2-3-6-9(12)13-7-4-5-8(11)10(14)15/h8H,2-7,11H2,1H3,(H2,12,13)(H,14,15)/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM50254450
((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)Show InChI InChI=1S/C8H17N3O2/c1-2-7(10)11-5-3-4-6(9)8(12)13/h6H,2-5,9H2,1H3,(H2,10,11)(H,12,13)/t6-/m0/s1 | PDB MMDB
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| PDB Article PubMed
| 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92905
(DDAH Inhibitor, 15)Show InChI InChI=1S/C11H23N3O2/c1-2-3-4-7-10(13)14-8-5-6-9(12)11(15)16/h9H,2-8,12H2,1H3,(H2,13,14)(H,15,16)/t9-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
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UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
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| Article PubMed
| 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM50072297
((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...)Show InChI InChI=1S/C7H15N3O2/c1-5(8)10-4-2-3-6(9)7(11)12/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12)/t6-/m0/s1 | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM92903
(L-Citrulline, 4)Show InChI InChI=1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1 | PDB MMDB
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DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
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UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
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UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
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| Article PubMed
| 1.40E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM92905
(DDAH Inhibitor, 15)Show InChI InChI=1S/C11H23N3O2/c1-2-3-4-7-10(13)14-8-5-6-9(12)11(15)16/h9H,2-8,12H2,1H3,(H2,13,14)(H,15,16)/t9-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| >1.90E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92903
(L-Citrulline, 4)Show InChI InChI=1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1 | PDB MMDB
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| DrugBank PDB Article PubMed
| 3.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92901
(ADMA, 3)Show InChI InChI=1S/C8H18N4O2/c1-12(2)8(10)11-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14)/t6-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM92900
(CHEMBL1835117 | L-Arginine, 2 | NMMA, 2)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |