Compile Data Set for Download or QSAR

Found 195 hits with Last Name = 'jo' and Initial = 'yh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphotransferase (Trypanosoma brucei)	BDBM43835 (Glucosamine derivative, 8 | MLS000582359 | N-cyclo...) Show SMILES [O-][N+](=O)c1ccc(N2CCCCC2)c(c1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C18H25N3O3/c22-18(19-14-7-3-1-4-8-14)16-13-15(21(23)24)9-10-17(16)20-11-5-2-6-12-20/h9-10,13-14H,1-8,11-12H2,(H,19,22)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	-31.7	5.00E+5	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43833 (2-hydroxy-N''''-(3-keto-5,5-dimethyl-cyclohexen-1-...) Show SMILES CC1(C)CC(=O)C=C(C1)NNC(=O)c1ccccc1O |c:6| Show InChI InChI=1S/C15H18N2O3/c1-15(2)8-10(7-11(18)9-15)16-17-14(20)12-5-3-4-6-13(12)19/h3-7,16,19H,8-9H2,1-2H3,(H,17,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	-29.1	2.00E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43832 (2-phenylcyclopropane-1,1-dicarboxylic acid diethyl...) Show SMILES CCOC(=O)C1(CC1c1ccccc1)C(=O)OCC Show InChI InChI=1S/C15H18O4/c1-3-18-13(16)15(14(17)19-4-2)10-12(15)11-8-6-5-7-9-11/h5-9,12H,3-4,10H2,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	-26.9	4.00E+5	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43834 (2-methoxy-4-[[4-(4-methylphenyl)-1-piperazinyl]met...) Show SMILES COc1cc(CN2CCN(CC2)c2ccc(C)cc2)cc(c1O)[N+]([O-])=O Show InChI InChI=1S/C19H23N3O4/c1-14-3-5-16(6-4-14)21-9-7-20(8-10-21)13-15-11-17(22(24)25)19(23)18(12-15)26-2/h3-6,11-12,23H,7-10,13H2,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.50E+4	-26.3	3.00E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43838 (4-O-[5-bromo-2-cyclopropyl-3-(4-methoxyphenyl)-7-m...) Show SMILES COC(=O)CCC(=O)OC1(C)C(=O)C(Br)=C2C=C(N(C=C2C1=O)C1CC1)c1ccc(OC)cc1 |c:16,19,t:14| Show InChI InChI=1S/C25H24BrNO7/c1-25(34-21(29)11-10-20(28)33-3)23(30)18-13-27(15-6-7-15)19(12-17(18)22(26)24(25)31)14-4-8-16(32-2)9-5-14/h4-5,8-9,12-13,15H,6-7,10-11H2,1-3H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	-25.8	3.00E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43837 ((4S,5R,6R)-1-(2-ethoxy-2-keto-ethyl)-2-keto-6-meth...) Show SMILES CCOC(=O)CN1[C@H](C)[C@@H]([C@H](CCc2ccccc2)NC1=O)C(=O)OC Show InChI InChI=1S/C19H26N2O5/c1-4-26-16(22)12-21-13(2)17(18(23)25-3)15(20-19(21)24)11-10-14-8-6-5-7-9-14/h5-9,13,15,17H,4,10-12H2,1-3H3,(H,20,24)/t13-,15+,17+/m1/s1	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.00E+4	-23.7	3.00E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43836 (Glucosamine derivative, 9 | MLS000580208 | N-(2,5-...) Show SMILES COc1ccc(OC)c(NC(=O)c2ccccc2NS(=O)(=O)c2cccc3cccnc23)c1 Show InChI InChI=1S/C24H21N3O5S/c1-31-17-12-13-21(32-2)20(15-17)26-24(28)18-9-3-4-10-19(18)27-33(29,30)22-11-5-7-16-8-6-14-25-23(16)22/h3-15,27H,1-2H3,(H,26,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.00E+5	-22.8	4.00E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43829 (Glucosamine derivative, 2 | MLS000568543 | SMR0001...) Show SMILES Oc1ccccc1N1CCN(CC1)C(=O)c1ccc2ccccc2n1 Show InChI InChI=1S/C20H19N3O2/c24-19-8-4-3-7-18(19)22-11-13-23(14-12-22)20(25)17-10-9-15-5-1-2-6-16(15)21-17/h1-10,24H,11-14H2	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.00E+5	-22.8	6.00E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43830 (5-(amoxymethyl)-3-[2-[(4-phenylthiazol-2-yl)hydraz...) Show SMILES CCCCCOCC1CC(CC(C)N=Nc2nc(cs2)-c2ccccc2)C(=O)O1 |w:13.12| Show InChI InChI=1S/C22H29N3O3S/c1-3-4-8-11-27-14-19-13-18(21(26)28-19)12-16(2)24-25-22-23-20(15-29-22)17-9-6-5-7-10-17/h5-7,9-10,15-16,18-19H,3-4,8,11-14H2,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.05E+5	-22.7	4.50E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei)	BDBM43831 (5-(4-fluorobenzyl)-4-keto-6,7-dihydropyrazolo[1,5-...) Show SMILES COC(=O)c1cc2C(=O)N(Cc3ccc(F)cc3)CCn2n1 Show InChI InChI=1S/C15H14FN3O3/c1-22-15(21)12-8-13-14(20)18(6-7-19(13)17-12)9-10-2-4-11(16)5-3-10/h2-5,8H,6-7,9H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.14E+5	-22.5	1.80E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50170264 (CHEMBL361931 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(Cl)c2)cc1 Show InChI InChI=1S/C20H26ClN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224228 (CHEMBL46233) Show SMILES CC(C)(C)C(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C26H36FN3O4S2/c1-25(2,3)20-10-9-18(19(13-20)16-34-23(31)26(4,5)6)15-29-24(35)28-14-17-8-11-22(21(27)12-17)30-36(7,32)33/h8-13,30H,14-16H2,1-7H3,(H2,28,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224175 (CHEMBL48061) Show SMILES CCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C24H34FN3O3S2/c1-6-7-12-31-22-14-19(24(2,3)4)10-9-18(22)16-27-23(32)26-15-17-8-11-21(20(25)13-17)28-33(5,29)30/h8-11,13-14,28H,6-7,12,15-16H2,1-5H3,(H2,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224176 (CHEMBL296963) Show SMILES NC(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C10H14N4O/c11-10(15)14-7-5-13(6-8-14)9-3-1-2-4-12-9/h1-4H,5-8H2,(H2,11,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160036 (CHEMBL183121 | N-(4-tert-Butyl-phenyl)-4-pyridin-2...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ccccn2)cc1 Show InChI InChI=1S/C22H22N2O/c1-22(2,3)18-11-13-19(14-12-18)24-21(25)17-9-7-16(8-10-17)20-6-4-5-15-23-20/h4-15H,1-3H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160028 (CHEMBL180138 | N-(4-tert-Butyl-phenyl)-4-(3-methyl...) Show SMILES Cc1cccnc1-c1ccc(cc1)C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C23H24N2O/c1-16-6-5-15-24-21(16)17-7-9-18(10-8-17)22(26)25-20-13-11-19(12-14-20)23(2,3)4/h5-15H,1-4H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20321 (3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20321 (3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley rat				Bioorg Med Chem Lett 13: 4389-93 (2003) BindingDB Entry DOI: 10.7270/Q2KH0QJX
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20321 (3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160033 (CHEMBL183795 | N-(4-Isopropyl-phenyl)-4-pyridin-2-...) Show SMILES CC(C)c1ccc(NC(=O)c2ccc(cc2)-c2ccccn2)cc1 Show InChI InChI=1S/C21H20N2O/c1-15(2)16-10-12-19(13-11-16)23-21(24)18-8-6-17(7-9-18)20-5-3-4-14-22-20/h3-15H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172566 (CHEMBL196291 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(I)c2)cc1 Show InChI InChI=1S/C20H26IN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172563 (1-(1H-Benzotriazol-5-ylmethyl)-3-(4-tert-butyl-ben...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc3nn[nH]c3c2)cc1 Show InChI InChI=1S/C19H23N5S/c1-19(2,3)15-7-4-13(5-8-15)11-20-18(25)21-12-14-6-9-16-17(10-14)23-24-22-16/h4-10H,11-12H2,1-3H3,(H2,20,21,25)(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20321 (3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Concentration required to inhibit [3H]-RTX radioligand binding towards transient receptor potential cation channel (subfamily V, member 1) expressed ...				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160039 (CHEMBL183752 | N-(4-tert-Butyl-phenyl)-4-(3-chloro...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccc2Cl)cc1 Show InChI InChI=1S/C22H21ClN2O/c1-22(2,3)17-10-12-18(13-11-17)25-21(26)16-8-6-15(7-9-16)20-19(23)5-4-14-24-20/h4-14H,1-3H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160030 (CHEMBL181478 | N-(4-tert-Butyl-phenyl)-4-pyrimidin...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccn2)cc1 Show InChI InChI=1S/C21H21N3O/c1-21(2,3)17-9-11-18(12-10-17)24-20(25)16-7-5-15(6-8-16)19-22-13-4-14-23-19/h4-14H,1-3H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224234 (CHEMBL45252) Show SMILES CCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C24H35N3O3S2/c1-6-7-14-30-22-15-20(24(2,3)4)11-10-19(22)17-26-23(31)25-16-18-8-12-21(13-9-18)27-32(5,28)29/h8-13,15,27H,6-7,14,16-17H2,1-5H3,(H2,25,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224229 (CHEMBL48998) Show SMILES CC(C)(C)COc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C25H37N3O3S2/c1-24(2,3)17-31-22-14-20(25(4,5)6)11-10-19(22)16-27-23(32)26-15-18-8-12-21(13-9-18)28-33(7,29)30/h8-14,28H,15-17H2,1-7H3,(H2,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224232 (CHEMBL296729) Show SMILES COCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C23H33N3O4S2/c1-23(2,3)19-9-8-18(21(14-19)30-13-12-29-4)16-25-22(31)24-15-17-6-10-20(11-7-17)26-32(5,27)28/h6-11,14,26H,12-13,15-16H2,1-5H3,(H2,24,25,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160027 (CHEMBL183045 | N-(4-tert-Butyl-phenyl)-4-(3-nitro-...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C22H21N3O3/c1-22(2,3)17-10-12-18(13-11-17)24-21(26)16-8-6-15(7-9-16)20-19(25(27)28)5-4-14-23-20/h4-14H,1-3H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224196 (CHEMBL43723) Show SMILES CC(C)(C)COc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C25H36FN3O3S2/c1-24(2,3)16-32-22-13-19(25(4,5)6)10-9-18(22)15-28-23(33)27-14-17-8-11-21(20(26)12-17)29-34(7,30)31/h8-13,29H,14-16H2,1-7H3,(H2,27,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224237 (CHEMBL431341) Show SMILES CCCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C25H37N3O3S2/c1-6-7-8-15-31-23-16-21(25(2,3)4)12-11-20(23)18-27-24(32)26-17-19-9-13-22(14-10-19)28-33(5,29)30/h9-14,16,28H,6-8,15,17-18H2,1-5H3,(H2,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224230 (CHEMBL47282) Show SMILES CC(C)(C)C(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C26H37N3O4S2/c1-25(2,3)21-11-10-19(20(14-21)17-33-23(30)26(4,5)6)16-28-24(34)27-15-18-8-12-22(13-9-18)29-35(7,31)32/h8-14,29H,15-17H2,1-7H3,(H2,27,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50170263 (CHEMBL189418 | N-{4-[3-(4-tert-Butyl-benzyl)-thiou...) Show SMILES CC(C)(C)c1ccc(C[N-]C(=[SH+])NCc2ccc(NS(C)(=O)=O)c(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C20H26N4O4S2/c1-20(2,3)16-8-5-14(6-9-16)12-21-19(29)22-13-15-7-10-17(23-30(4,27)28)18(11-15)24(25)26/h5-11,23H,12-13H2,1-4H3,(H2,21,22,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172578 (CHEMBL196085 | N-{2-Bromo-4-[3-(4-tert-butyl-benzy...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(Br)c2)cc1 Show InChI InChI=1S/C20H26BrN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20315 (3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20315 (3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley rat				Bioorg Med Chem Lett 13: 4389-93 (2003) BindingDB Entry DOI: 10.7270/Q2KH0QJX
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20315 (3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160031 (CHEMBL180902 | N-(4-tert-Butyl-phenyl)-4-(3-triflu...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ncccc2C(F)(F)F)cc1 Show InChI InChI=1S/C23H21F3N2O/c1-22(2,3)17-10-12-18(13-11-17)28-21(29)16-8-6-15(7-9-16)20-19(23(24,25)26)5-4-14-27-20/h4-14H,1-3H3,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224239 (CHEMBL295773) Show SMILES CCCCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C26H39N3O3S2/c1-6-7-8-9-16-32-24-17-22(26(2,3)4)13-12-21(24)19-28-25(33)27-18-20-10-14-23(15-11-20)29-34(5,30)31/h10-15,17,29H,6-9,16,18-19H2,1-5H3,(H2,27,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160041 (4-Pyridin-2-yl-piperazine-1-carboxylic acid (4-ter...) Show SMILES CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)c2ccccn2)cc1 Show InChI InChI=1S/C20H26N4O/c1-20(2,3)16-7-9-17(10-8-16)22-19(25)24-14-12-23(13-15-24)18-6-4-5-11-21-18/h4-11H,12-15H2,1-3H3,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172590 (CHEMBL196255 | N-{4-[3-(3,5-Di-tert-butyl-benzyl)-...) Show SMILES CC(C)(C)c1cc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc(c1)C(C)(C)C Show InChI InChI=1S/C24H34FN3O2S2/c1-23(2,3)18-10-17(11-19(13-18)24(4,5)6)15-27-22(31)26-14-16-8-9-21(20(25)12-16)28-32(7,29)30/h8-13,28H,14-15H2,1-7H3,(H2,26,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224100 (CHEMBL44057) Show SMILES CC(C)(C)C(=O)Oc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C25H35N3O4S2/c1-24(2,3)19-11-10-18(21(14-19)32-22(29)25(4,5)6)16-27-23(33)26-15-17-8-12-20(13-9-17)28-34(7,30)31/h8-14,28H,15-16H2,1-7H3,(H2,26,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172567 (CHEMBL197222 | N-{4-[3-(4-tert-Butyl-benzyl)-ureid...) Show SMILES CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)c(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C20H26N4O5S/c1-20(2,3)16-8-5-14(6-9-16)12-21-19(25)22-13-15-7-10-17(23-30(4,28)29)18(11-15)24(26)27/h5-11,23H,12-13H2,1-4H3,(H2,21,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172587 (CHEMBL197770 | N-{4-[3-(4-tert-Butyl-benzyl)-ureid...) Show SMILES CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)c(Cl)c2)cc1 Show InChI InChI=1S/C20H26ClN3O3S/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(25)23-13-15-7-10-18(17(21)11-15)24-28(4,26)27/h5-11,24H,12-13H2,1-4H3,(H2,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224235 (CHEMBL45417) Show SMILES CCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C23H33N3O3S2/c1-6-13-29-21-14-19(23(2,3)4)10-9-18(21)16-25-22(30)24-15-17-7-11-20(12-8-17)26-31(5,27)28/h7-12,14,26H,6,13,15-16H2,1-5H3,(H2,24,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50160042 (CHEMBL183835 | N-(4-tert-Butyl-phenyl)-4-pyridin-4...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)-c2ccncc2)cc1 Show InChI InChI=1S/C22H22N2O/c1-22(2,3)19-8-10-20(11-9-19)24-21(25)18-6-4-16(5-7-18)17-12-14-23-15-13-17/h4-15H,1-3H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonistic activity on VR1 receptor in [Ca2+] influx assay in rat dorsal root ganglion				Bioorg Med Chem Lett 15: 631-4 (2005) Article DOI: 10.1016/j.bmcl.2004.11.033 BindingDB Entry DOI: 10.7270/Q25T3JZR
					More data for this Ligand-Target Pair
Pancreatic triacylglycerol lipase (Sus scrofa (Pig))	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O |r| Show InChI InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Chungbuk National University Curated by ChEMBL					Assay Description Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate assessed as formation of p-nitrophenol preincubated for 15 mins foll...				Bioorg Med Chem Lett 25: 2269-74 (2015) Article DOI: 10.1016/j.bmcl.2015.04.045 BindingDB Entry DOI: 10.7270/Q2GF0W7B
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50172598 (CHEMBL197781 | N-(4-[({4-tert-Butylbenzyl}aminocar...) Show SMILES CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O3S/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(25)23-13-15-7-10-18(17(21)11-15)24-28(4,26)27/h5-11,24H,12-13H2,1-4H3,(H2,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory effect on capsaicin (0.5 uM)-induced calcium uptake in rat DRG neurons upon incubation at RT for 10 minutes				J Med Chem 48: 5823-36 (2005) Article DOI: 10.1021/jm0502790 BindingDB Entry DOI: 10.7270/Q2057FGN
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50484888 (CHEMBL2011797) Show SMILES COc1ccc(C(=O)NCc2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C15H15NO5/c1-21-11-4-5-12(14(19)7-11)15(20)16-8-9-2-3-10(17)6-13(9)18/h2-7,17-19H,8H2,1H3,(H,16,20)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation R&D Center Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem Lett 22: 2110-3 (2012) Article DOI: 10.1016/j.bmcl.2011.12.144 BindingDB Entry DOI: 10.7270/Q2T72M9Q
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224226 (CHEMBL45455) Show SMILES COc1cc(CC\N=C(/S)NCCc2ccccc2)ccc1O Show InChI InChI=1S/C18H22N2O2S/c1-22-17-13-15(7-8-16(17)21)10-12-20-18(23)19-11-9-14-5-3-2-4-6-14/h2-8,13,21H,9-12H2,1H3,(H2,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair

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