Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50155307 (CHEMBL3781796) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting method | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50155307 (CHEMBL3781796) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]tyr11-SRIF from human sst4 receptor after 60 mins by liquid scintillation counting method | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50155308 (CHEMBL3780791) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]tyr11-SRIF from human sst4 receptor after 60 mins by liquid scintillation counting method | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50051567 (5-{(2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[2-(1H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Binding affinity to sst4 receptor (unknown origin) | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50155306 (CHEMBL3781875) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Binding affinity to human sst4 receptor | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50155305 (CHEMBL3782021) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]-SRIF14 from human sst4 receptor | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50155308 (CHEMBL3780791) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting method | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50051567 (5-{(2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[2-(1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Binding affinity to sst2 receptor (unknown origin) | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50155306 (CHEMBL3781875) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Binding affinity to human sst2 receptor | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50155309 (CHEMBL3780496) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 6.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]tyr11-SRIF from human sst2 receptor after 60 mins by liquid scintillation counting method | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50155309 (CHEMBL3780496) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 7.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Gothenburg Curated by ChEMBL | Assay Description Displacement of [125I]tyr11-SRIF from human sst4 receptor after 60 mins by liquid scintillation counting method | Eur J Med Chem 114: 59-64 (2016) Article DOI: 10.1016/j.ejmech.2016.02.046 BindingDB Entry DOI: 10.7270/Q2WH2RWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 1, cytoplasmic (Homo sapiens (Human)) | BDBM531217 (US11208384, Example 1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6HDX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM531217 (US11208384, Example 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Small molecule inhibition of recombinant thioredoxin reductase 1 (TrxR1) and gluthathione reductase (GR) was examined in 96-well plate format. 30 nM ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2SX6HDX | |||||||||||
More data for this Ligand-Target Pair |