Compile Data Set for Download or QSAR

Found 240 hits with Last Name = 'bayeh' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105306 (CHEMBL3597782) Show SMILES Fc1ccc(Br)c(F)c1[C@H]1C[C@H](Nc2nnnn12)c1cccc(Br)c1 |r| Show InChI InChI=1S/C16H11Br2F2N5/c17-9-3-1-2-8(6-9)12-7-13(25-16(21-12)22-23-24-25)14-11(19)5-4-10(18)15(14)20/h1-6,12-13H,7H2,(H,21,22,24)/t12-,13+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105310 (CHEMBL3597786) Show SMILES Fc1cc(Br)cc(c1)[C@@H]1C[C@H](c2cccc(Br)c2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H12Br2FN5/c17-11-3-1-2-9(4-11)15-8-14(20-16-21-22-23-24(15)16)10-5-12(18)7-13(19)6-10/h1-7,14-15H,8H2,(H,20,21,23)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388838 (CHEMBL2062897) Show SMILES NC(=S)NN=C1CCSc2cc(F)c(F)cc12 |w:4.3| Show InChI InChI=1S/C10H9F2N3S2/c11-6-3-5-8(14-15-10(13)16)1-2-17-9(5)4-7(6)12/h3-4H,1-2H2,(H3,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388851 (CHEMBL2062909) Show SMILES NC(=S)NN=C1CCSc2ccc(cc12)[N+]([O-])=O |w:4.3| Show InChI InChI=1S/C10H10N4O2S2/c11-10(17)13-12-8-3-4-18-9-2-1-6(14(15)16)5-7(8)9/h1-2,5H,3-4H2,(H3,11,13,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105280 (CHEMBL3597780) Show SMILES Clc1ccc(Br)cc1[C@H]1C[C@H](Nc2nnnn12)c1cccc(Br)c1 |r| Show InChI InChI=1S/C16H12Br2ClN5/c17-10-3-1-2-9(6-10)14-8-15(24-16(20-14)21-22-23-24)12-7-11(18)4-5-13(12)19/h1-7,14-15H,8H2,(H,20,21,23)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105308 (CHEMBL3597784) Show SMILES Fc1cc(Br)cc(c1)[C@@H]1C[C@H](c2ccccc2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H13BrFN5/c17-12-6-11(7-13(18)8-12)14-9-15(10-4-2-1-3-5-10)23-16(19-14)20-21-22-23/h1-8,14-15H,9H2,(H,19,20,22)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105278 (CHEMBL3597778) Show SMILES Brc1cccc(c1)[C@@H]1C[C@H](c2cccc(I)c2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H13BrIN5/c17-12-5-1-3-10(7-12)14-9-15(11-4-2-6-13(18)8-11)23-16(19-14)20-21-22-23/h1-8,14-15H,9H2,(H,19,20,22)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105276 (CHEMBL3597698) Show SMILES Brc1cccc(c1)[C@@H]1C[C@H](c2cccc(Br)c2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H13Br2N5/c17-12-5-1-3-10(7-12)14-9-15(11-4-2-6-13(18)8-11)23-16(19-14)20-21-22-23/h1-8,14-15H,9H2,(H,19,20,22)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Procathepsin L (Homo sapiens (Human))	BDBM50388835 (CHEMBL2062926) Show SMILES NC(=S)NN=C1CCS(=O)(=O)c2ccc(cc12)[N+]([O-])=O |w:4.3| Show InChI InChI=1S/C10H10N4O4S2/c11-10(19)13-12-8-3-4-20(17,18)9-2-1-6(14(15)16)5-7(8)9/h1-2,5H,3-4H2,(H3,11,13,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388837 (CHEMBL2062896) Show SMILES NC(=S)NN=C1CCSc2ccc(Br)cc12 |w:4.3| Show InChI InChI=1S/C10H10BrN3S2/c11-6-1-2-9-7(5-6)8(3-4-16-9)13-14-10(12)15/h1-2,5H,3-4H2,(H3,12,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491138 (CHEMBL2376019) Show SMILES NC(=S)N\N=C1/CCNc2ccc(Br)cc12 Show InChI InChI=1S/C10H11BrN4S/c11-6-1-2-8-7(5-6)9(3-4-13-8)14-15-10(12)16/h1-2,5,13H,3-4H2,(H3,12,15,16)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105274 (CHEMBL3597696) Show SMILES Clc1ccccc1[C@H]1C[C@H](Nc2nnnn12)c1cccc(Br)c1 |r| Show InChI InChI=1S/C16H13BrClN5/c17-11-5-3-4-10(8-11)14-9-15(12-6-1-2-7-13(12)18)23-16(19-14)20-21-22-23/h1-8,14-15H,9H2,(H,19,20,22)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388842 (CHEMBL2062901) Show SMILES Cc1ccc2SCCC(=NNC(N)=S)c2c1 |w:9.9| Show InChI InChI=1S/C11H13N3S2/c1-7-2-3-10-8(6-7)9(4-5-16-10)13-14-11(12)15/h2-3,6H,4-5H2,1H3,(H3,12,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM87123 (3,4-bis(fluoranyl)-N-[2-[1-(3-fluorophenyl)-4-oxid...) Show SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(F)c(F)c2)CC1 Show InChI InChI=1S/C22H23F3N4O2/c23-16-2-1-3-17(13-16)29-14-27-21(31)22(29)6-9-28(10-7-22)11-8-26-20(30)15-4-5-18(24)19(25)12-15/h1-5,12-13H,6-11,14H2,(H,26,30)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491134 (CHEMBL2376003) Show SMILES NC(=S)N\N=C1/CCN(c2ccc(cc12)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C10H10N6O4S/c11-10(21)13-12-8-3-4-14(16(19)20)9-2-1-6(15(17)18)5-7(8)9/h1-2,5H,3-4H2,(H3,11,13,21)/b12-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105268 (CHEMBL3597690) Show SMILES Brc1cccc(c1)[C@@H]1C[C@H](c2ccccc2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H14BrN5/c17-13-8-4-7-12(9-13)14-10-15(11-5-2-1-3-6-11)22-16(18-14)19-20-21-22/h1-9,14-15H,10H2,(H,18,19,21)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388848 (CHEMBL2062907) Show SMILES NC(=S)NN=C1CCSc2ccc(OC(F)(F)F)cc12 |w:4.3| Show InChI InChI=1S/C11H10F3N3OS2/c12-11(13,14)18-6-1-2-9-7(5-6)8(3-4-20-9)16-17-10(15)19/h1-2,5H,3-4H2,(H3,15,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	256	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388832 (CHEMBL2062923) Show SMILES NC(=S)NN=C1CCS(=O)(=O)c2ccc(cc12)C(F)(F)F |w:4.3| Show InChI InChI=1S/C11H10F3N3O2S2/c12-11(13,14)6-1-2-9-7(5-6)8(16-17-10(15)20)3-4-21(9,18)19/h1-2,5H,3-4H2,(H3,15,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388847 (CHEMBL2062906) Show SMILES NC(=S)NN=C1CCSc2ccc(cc12)C(F)(F)F |w:4.3| Show InChI InChI=1S/C11H10F3N3S2/c12-11(13,14)6-1-2-9-7(5-6)8(3-4-19-9)16-17-10(15)18/h1-2,5H,3-4H2,(H3,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105272 (CHEMBL3597694) Show SMILES Brc1cccc(c1)[C@@H]1C[C@H](c2ccccc2Br)n2nnnc2N1 |r| Show InChI InChI=1S/C16H13Br2N5/c17-11-5-3-4-10(8-11)14-9-15(12-6-1-2-7-13(12)18)23-16(19-14)20-21-22-23/h1-8,14-15H,9H2,(H,19,20,22)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491155 (CHEMBL2376004) Show SMILES NC(=S)N\N=C1/CCNc2c1cc(cc2[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C10H10N6O4S/c11-10(21)14-13-7-1-2-12-9-6(7)3-5(15(17)18)4-8(9)16(19)20/h3-4,12H,1-2H2,(H3,11,14,21)/b13-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491154 (CHEMBL1975473) Show SMILES NC(=S)N\N=C1/CCOc2ccc(Cl)cc12 Show InChI InChI=1S/C10H10ClN3OS/c11-6-1-2-9-7(5-6)8(3-4-15-9)13-14-10(12)16/h1-2,5H,3-4H2,(H3,12,14,16)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	369	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388841 (CHEMBL2062900) Show SMILES NC(=S)NN=C1CCSc2c(F)cc(Br)cc12 |w:4.3| Show InChI InChI=1S/C10H9BrFN3S2/c11-5-3-6-8(14-15-10(13)16)1-2-17-9(6)7(12)4-5/h3-4H,1-2H2,(H3,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	434	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491135 (CHEMBL2376002) Show SMILES NC(=S)N\N=C1/CCNc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C10H11N5O2S/c11-10(18)14-13-9-3-4-12-8-2-1-6(15(16)17)5-7(8)9/h1-2,5,12H,3-4H2,(H3,11,14,18)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	449	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50189278 (6-bromo-2,3-dihydro-4H-thiochromen-4-one thiosemic...) Show SMILES NC(=S)NN=C1CCS(=O)(=O)c2ccc(Br)cc12 |w:4.3| Show InChI InChI=1S/C10H10BrN3O2S2/c11-6-1-2-9-7(5-6)8(13-14-10(12)17)3-4-18(9,15)16/h1-2,5H,3-4H2,(H3,12,14,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	574	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491141 (CHEMBL2376012) Show SMILES NC(=S)N\N=C1/CCCSc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O2S2/c12-11(18)14-13-9-2-1-5-19-10-4-3-7(15(16)17)6-8(9)10/h3-4,6H,1-2,5H2,(H3,12,14,18)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	658	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388864 (CHEMBL2062895) Show SMILES NC(=S)NN=C1CCSc2ccc(F)cc12 |w:4.3| Show InChI InChI=1S/C10H10FN3S2/c11-6-1-2-9-7(5-6)8(3-4-16-9)13-14-10(12)15/h1-2,5H,3-4H2,(H3,12,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	741	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105270 (CHEMBL3597692) Show SMILES Ic1cccc(c1)[C@@H]1C[C@H](c2ccccc2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H14IN5/c17-13-8-4-7-12(9-13)14-10-15(11-5-2-1-3-6-11)22-16(18-14)19-20-21-22/h1-9,14-15H,10H2,(H,18,19,21)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Endothelial PAS domain-containing protein 1 (Homo sapiens (Human))	BDBM50105310 (CHEMBL3597786) Show SMILES Fc1cc(Br)cc(c1)[C@@H]1C[C@H](c2cccc(Br)c2)n2nnnc2N1 |r| Show InChI InChI=1S/C16H12Br2FN5/c17-11-3-1-2-9(4-11)15-8-14(20-16-21-22-23-24(15)16)10-5-12(18)7-13(19)6-10/h1-7,14-15H,8H2,(H,20,21,23)/t14-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of HIF-2alpha in human Hep3B cells assessed as downregulation of EPO mRNA expression by RT-PCR analysis				J Med Chem 58: 5930-41 (2015) Article DOI: 10.1021/acs.jmedchem.5b00529 BindingDB Entry DOI: 10.7270/Q2G162K1
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388859 (CHEMBL2062918) Show SMILES NC(=S)NN=C1CCS(=O)(=O)c2c(F)cc(Br)cc12 |w:4.3| Show InChI InChI=1S/C10H9BrFN3O2S2/c11-5-3-6-8(14-15-10(13)18)1-2-19(16,17)9(6)7(12)4-5/h3-4H,1-2H2,(H3,13,15,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388839 (CHEMBL2062898) Show SMILES NC(=S)NN=C1CCSc2c(F)cc(F)cc12 |w:4.3| Show InChI InChI=1S/C10H9F2N3S2/c11-5-3-6-8(14-15-10(13)16)1-2-17-9(6)7(12)4-5/h3-4H,1-2H2,(H3,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491163 (CHEMBL2376008) Show SMILES NC(=S)N\N=C1/CC[S+]([O-])c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C10H10N4O3S2/c11-10(18)13-12-8-3-4-19(17)9-2-1-6(14(15)16)5-7(8)9/h1-2,5H,3-4H2,(H3,11,13,18)/b12-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388843 (CHEMBL2062902) Show SMILES CCc1ccc2SCCC(=NNC(N)=S)c2c1 |w:10.10| Show InChI InChI=1S/C12H15N3S2/c1-2-8-3-4-11-9(7-8)10(5-6-17-11)14-15-12(13)16/h3-4,7H,2,5-6H2,1H3,(H3,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388856 (CHEMBL2062915) Show SMILES NC(=S)NN=C1CCS(=O)(=O)c2cc(F)c(F)cc12 |w:4.3| Show InChI InChI=1S/C10H9F2N3O2S2/c11-6-3-5-8(14-15-10(13)18)1-2-19(16,17)9(5)4-7(6)12/h3-4H,1-2H2,(H3,13,15,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388833 (CHEMBL2062924) Show SMILES NC(=S)NN=C1CCS(=O)(=O)c2ccc(OC(F)(F)F)cc12 |w:4.3| Show InChI InChI=1S/C11H10F3N3O3S2/c12-11(13,14)20-6-1-2-9-7(5-6)8(16-17-10(15)21)3-4-22(9,18)19/h1-2,5H,3-4H2,(H3,15,17,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50388861 (CHEMBL2062920) Show SMILES CCc1ccc2c(c1)C(CCS2(=O)=O)=NNC(N)=S |w:14.16| Show InChI InChI=1S/C12H15N3O2S2/c1-2-8-3-4-11-9(7-8)10(14-15-12(13)18)5-6-19(11,16)17/h3-4,7H,2,5-6H2,1H3,(H3,13,15,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L using Z-R-R-AMC as substrate preincubated with compound for 5 mins measured after 20 mins by fluorescence analy...				ACS Med Chem Lett 3: 450-453 (2012) Article DOI: 10.1021/ml200299g BindingDB Entry DOI: 10.7270/Q2QC04JR
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491139 (CHEMBL2376016) Show SMILES NC(=S)N\N=C1/CCc2ccc(Br)cc12 Show InChI InChI=1S/C10H10BrN3S/c11-7-3-1-6-2-4-9(8(6)5-7)13-14-10(12)15/h1,3,5H,2,4H2,(H3,12,14,15)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491140 (CHEMBL2376014) Show SMILES NC(=S)N\N=C1/CCCS(=O)(=O)c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O4S2/c12-11(20)14-13-9-2-1-5-21(18,19)10-4-3-7(15(16)17)6-8(9)10/h3-4,6H,1-2,5H2,(H3,12,14,20)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491141 (CHEMBL2376012) Show SMILES NC(=S)N\N=C1/CCCSc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C11H12N4O2S2/c12-11(18)14-13-9-2-1-5-19-10-4-3-7(15(16)17)6-8(9)10/h3-4,6H,1-2,5H2,(H3,12,14,18)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491142 (CHEMBL2376010) Show SMILES NC(=N)N\N=C1/CCSc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C10H11N5O2S/c11-10(12)14-13-8-3-4-18-9-2-1-6(15(16)17)5-7(8)9/h1-2,5H,3-4H2,(H4,11,12,14)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491143 (CHEMBL2376007) Show SMILES NC(=S)N\N=C1/CCS(=O)(=O)c2ccc(N)cc12 Show InChI InChI=1S/C10H12N4O2S2/c11-6-1-2-9-7(5-6)8(13-14-10(12)17)3-4-18(9,15)16/h1-2,5H,3-4,11H2,(H3,12,14,17)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491144 (CHEMBL2376005) Show SMILES NC(=S)N\N=C1/CC(Oc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H15N3OS/c17-16(21)19-18-13-10-15(11-6-2-1-3-7-11)20-14-9-5-4-8-12(13)14/h1-9,15H,10H2,(H3,17,19,21)/b18-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491145 (CHEMBL1971086) Show SMILES NC(=S)N\N=C1/CCCCc2ccccc12 Show InChI InChI=1S/C12H15N3S/c13-12(16)15-14-11-8-4-2-6-9-5-1-3-7-10(9)11/h1,3,5,7H,2,4,6,8H2,(H3,13,15,16)/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491146 (CHEMBL2376025) Show SMILES NC(=S)N\N=C1/CCCc2cc(N)ccc12 Show InChI InChI=1S/C11H14N4S/c12-8-4-5-9-7(6-8)2-1-3-10(9)14-15-11(13)16/h4-6H,1-3,12H2,(H3,13,15,16)/b14-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491147 (CHEMBL2376024) Show SMILES NC(=S)N\N=C1/CCCc2c(O)cccc12 Show InChI InChI=1S/C11H13N3OS/c12-11(16)14-13-9-5-1-4-8-7(9)3-2-6-10(8)15/h2-3,6,15H,1,4-5H2,(H3,12,14,16)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50491148 (CHEMBL2376022) Show SMILES COc1ccc2\C(CCCc2c1)=N\NC(N)=S Show InChI InChI=1S/C12H15N3OS/c1-16-9-5-6-10-8(7-9)3-2-4-11(10)14-15-12(13)17/h5-7H,2-4H2,1H3,(H3,13,15,17)/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin B using Z-Arg-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491149 (CHEMBL2375999) Show SMILES NC(=S)N\N=C1/CCNc2c(Cc3ccccc3)cccc12 Show InChI InChI=1S/C17H18N4S/c18-17(22)21-20-15-9-10-19-16-13(7-4-8-14(15)16)11-12-5-2-1-3-6-12/h1-8,19H,9-11H2,(H3,18,21,22)/b20-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491150 (CHEMBL2376017) Show SMILES NC(=S)N\N=C1/CC(Nc2ccccc2)c2ccc(Br)cc12 Show InChI InChI=1S/C16H15BrN4S/c17-10-6-7-12-13(8-10)15(20-21-16(18)22)9-14(12)19-11-4-2-1-3-5-11/h1-8,14,19H,9H2,(H3,18,21,22)/b20-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491139 (CHEMBL2376016) Show SMILES NC(=S)N\N=C1/CCc2ccc(Br)cc12 Show InChI InChI=1S/C10H10BrN3S/c11-7-3-1-6-2-4-9(8(6)5-7)13-14-10(12)15/h1,3,5H,2,4H2,(H3,12,14,15)/b13-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50491142 (CHEMBL2376010) Show SMILES NC(=N)N\N=C1/CCSc2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C10H11N5O2S/c11-10(12)14-13-8-3-4-18-9-2-1-6(15(16)17)5-7(8)9/h1-2,5H,3-4H2,(H4,11,12,14)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Baylor University Curated by ChEMBL					Assay Description Inhibition of human liver Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate incubated for 5 mins prior to substrate addition measured for ...				Bioorg Med Chem Lett 23: 2801-7 (2013) Article DOI: 10.1016/j.bmcl.2012.12.025 BindingDB Entry DOI: 10.7270/Q2NS0XSX
					More data for this Ligand-Target Pair

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