Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-hexosaminidase subunit beta (Homo sapiens (Human)) | BDBM304400 (US10143668, Compound 1d) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GRI BIO, INC. US Patent | Assay Description Buffers and solutions: Phosphate buffered saline (PBS) and 1 M HEPES were provided by the in-house service facility. Tyrode's buffer (TyB) consis... | US Patent US10143668 (2018) BindingDB Entry DOI: 10.7270/Q2K35WQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit beta (Homo sapiens (Human)) | BDBM304327 (US10143668, Compound 1a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GRI BIO, INC. US Patent | Assay Description Buffers and solutions: Phosphate buffered saline (PBS) and 1 M HEPES were provided by the in-house service facility. Tyrode's buffer (TyB) consis... | US Patent US10143668 (2018) BindingDB Entry DOI: 10.7270/Q2K35WQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit beta (Homo sapiens (Human)) | BDBM50034220 (2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GRI BIO, INC. US Patent | Assay Description Buffers and solutions: Phosphate buffered saline (PBS) and 1 M HEPES were provided by the in-house service facility. Tyrode's buffer (TyB) consis... | US Patent US10143668 (2018) BindingDB Entry DOI: 10.7270/Q2K35WQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit beta (Homo sapiens (Human)) | BDBM304339 (US10143668, Compound 1b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GRI BIO, INC. US Patent | Assay Description Buffers and solutions: Phosphate buffered saline (PBS) and 1 M HEPES were provided by the in-house service facility. Tyrode's buffer (TyB) consis... | US Patent US10143668 (2018) BindingDB Entry DOI: 10.7270/Q2K35WQ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-hexosaminidase subunit beta (Homo sapiens (Human)) | BDBM304357 (US10143668, Compound 1c) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GRI BIO, INC. US Patent | Assay Description Buffers and solutions: Phosphate buffered saline (PBS) and 1 M HEPES were provided by the in-house service facility. Tyrode's buffer (TyB) consis... | US Patent US10143668 (2018) BindingDB Entry DOI: 10.7270/Q2K35WQ0 | |||||||||||
More data for this Ligand-Target Pair |