Compile Data Set for Download or QSAR

Found 167 hits with Last Name = 'chang' and Initial = 'pt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50056188 (CHEMBL3329654) Show SMILES CN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1 Show InChI InChI=1S/C25H28FN7O3/c1-33(9-10-34)8-3-11-36-20-6-7-21-22(15-20)27-16-28-25(21)30-23-13-19(31-32-23)14-24(35)29-18-5-2-4-17(26)12-18/h2,4-7,12-13,15-16,34H,3,8-11,14H2,1H3,(H,29,35)(H2,27,28,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056199 (CHEMBL3329684) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C31H33FN6O5/c1-17-25(34-18(2)27(17)30(41)33-10-13-38-11-4-5-12-38)16-23-21-8-6-19(14-26(21)36-29(23)40)35-31(42)37-28(39)22-9-7-20(43-3)15-24(22)32/h6-9,14-16,34H,4-5,10-13H2,1-3H3,(H,33,41)(H,36,40)(H2,35,37,39,42)/b23-16-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50056199 (CHEMBL3329684) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C31H33FN6O5/c1-17-25(34-18(2)27(17)30(41)33-10-13-38-11-4-5-12-38)16-23-21-8-6-19(14-26(21)36-29(23)40)35-31(42)37-28(39)22-9-7-20(43-3)15-24(22)32/h6-9,14-16,34H,4-5,10-13H2,1-3H3,(H,33,41)(H,36,40)(H2,35,37,39,42)/b23-16-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50051957 (CHEMBL3322566) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C32H36N6O5/c1-19-26(34-20(2)30(19)32(42)33-12-15-38-13-4-5-14-38)17-25-24-11-8-22(16-27(24)37-31(25)41)36-29(40)18-28(39)35-21-6-9-23(43-3)10-7-21/h6-11,16-17,34H,4-5,12-15,18H2,1-3H3,(H,33,42)(H,35,39)(H,36,40)(H,37,41)/b25-17-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50051941 (CHEMBL3322565) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C26H24N4O6/c1-13-20(27-14(2)24(13)26(34)35)11-19-18-9-6-16(10-21(18)30-25(19)33)29-23(32)12-22(31)28-15-4-7-17(36-3)8-5-15/h4-11,27H,12H2,1-3H3,(H,28,31)(H,29,32)(H,30,33)(H,34,35)/b19-11-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056146 (CHEMBL3329669) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1 Show InChI InChI=1S/C27H26N4O6/c1-14-19(10-11-24(32)33)15(2)28-22(14)13-21-20-9-6-17(12-23(20)30-26(21)35)29-27(36)31-25(34)16-4-7-18(37-3)8-5-16/h4-9,12-13,28H,10-11H2,1-3H3,(H,30,35)(H,32,33)(H2,29,31,34,36)/b21-13-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056142 (CHEMBL3329673) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(CCC(O)=O)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C27H25FN4O6/c1-13-17(8-9-24(33)34)14(2)29-22(13)12-20-18-6-4-15(10-23(18)31-26(20)36)30-27(37)32-25(35)19-7-5-16(38-3)11-21(19)28/h4-7,10-12,29H,8-9H2,1-3H3,(H,31,36)(H,33,34)(H2,30,32,35,37)/b20-12-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056140 (CHEMBL3329675) Show SMILES COc1ccc(C(=O)NC(=O)Nc2cc3NC(=O)\C(=C/c4[nH]c(C)c(CCC(O)=O)c4C)c3cc2F)c(F)c1 Show InChI InChI=1S/C27H24F2N4O6/c1-12-15(6-7-24(34)35)13(2)30-21(12)10-18-17-9-20(29)23(11-22(17)31-26(18)37)32-27(38)33-25(36)16-5-4-14(39-3)8-19(16)28/h4-5,8-11,30H,6-7H2,1-3H3,(H,31,37)(H,34,35)(H2,32,33,36,38)/b18-10-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50051957 (CHEMBL3322566) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C32H36N6O5/c1-19-26(34-20(2)30(19)32(42)33-12-15-38-13-4-5-14-38)17-25-24-11-8-22(16-27(24)37-31(25)41)36-29(40)18-28(39)35-21-6-9-23(43-3)10-7-21/h6-11,16-17,34H,4-5,12-15,18H2,1-3H3,(H,33,42)(H,35,39)(H,36,40)(H,37,41)/b25-17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056145 (CHEMBL3329670) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1cc2NC(=O)\C(=C/c3[nH]c(C)c(C(O)=O)c3C)c2cc1F Show InChI InChI=1S/C25H21FN4O6/c1-11-18(27-12(2)21(11)24(33)34)9-16-15-8-17(26)20(10-19(15)28-23(16)32)29-25(35)30-22(31)13-4-6-14(36-3)7-5-13/h4-10,27H,1-3H3,(H,28,32)(H,33,34)(H2,29,30,31,35)/b16-9-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056151 (CHEMBL3329668) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3[nH]c(C)c(CC(O)=O)c3C)C(=O)Nc2c1 Show InChI InChI=1S/C26H24N4O6/c1-13-19(12-23(31)32)14(2)27-21(13)11-20-18-9-6-16(10-22(18)29-25(20)34)28-26(35)30-24(33)15-4-7-17(36-3)8-5-15/h4-11,27H,12H2,1-3H3,(H,29,34)(H,31,32)(H2,28,30,33,35)/b20-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056155 (CHEMBL3329664) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3[nH]c(C)c(C(O)=O)c3C)C(=O)Nc2c1 Show InChI InChI=1S/C25H22N4O6/c1-12-19(26-13(2)21(12)24(32)33)11-18-17-9-6-15(10-20(17)28-23(18)31)27-25(34)29-22(30)14-4-7-16(35-3)8-5-14/h4-11,26H,1-3H3,(H,28,31)(H,32,33)(H2,27,29,30,34)/b18-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50051957 (CHEMBL3322566) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C32H36N6O5/c1-19-26(34-20(2)30(19)32(42)33-12-15-38-13-4-5-14-38)17-25-24-11-8-22(16-27(24)37-31(25)41)36-29(40)18-28(39)35-21-6-9-23(43-3)10-7-21/h6-11,16-17,34H,4-5,12-15,18H2,1-3H3,(H,33,42)(H,35,39)(H,36,40)(H,37,41)/b25-17-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056143 (CHEMBL3329672) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C25H21FN4O6/c1-11-19(27-12(2)21(11)24(33)34)10-17-15-6-4-13(8-20(15)29-23(17)32)28-25(35)30-22(31)16-7-5-14(36-3)9-18(16)26/h4-10,27H,1-3H3,(H,29,32)(H,33,34)(H2,28,30,31,35)/b17-10-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50056199 (CHEMBL3329684) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C31H33FN6O5/c1-17-25(34-18(2)27(17)30(41)33-10-13-38-11-4-5-12-38)16-23-21-8-6-19(14-26(21)36-29(23)40)35-31(42)37-28(39)22-9-7-20(43-3)15-24(22)32/h6-9,14-16,34H,4-5,10-13H2,1-3H3,(H,33,41)(H,36,40)(H2,35,37,39,42)/b23-16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Lck (unknown origin)				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50056146 (CHEMBL3329669) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3[nH]c(C)c(CCC(O)=O)c3C)C(=O)Nc2c1 Show InChI InChI=1S/C27H26N4O6/c1-14-19(10-11-24(32)33)15(2)28-22(14)13-21-20-9-6-17(12-23(20)30-26(21)35)29-27(36)31-25(34)16-4-7-18(37-3)8-5-16/h4-9,12-13,28H,10-11H2,1-3H3,(H,30,35)(H,32,33)(H2,29,31,34,36)/b21-13-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50052075 (CHEMBL3322595) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)c4c[nH]cc(-c5ccc(F)cc5)c4=O)ccc23)c(C)c1C(=O)N1CCOCC1 Show InChI InChI=1S/C32H28FN5O5/c1-17-26(35-18(2)28(17)32(42)38-9-11-43-12-10-38)14-23-22-8-7-21(13-27(22)37-30(23)40)36-31(41)25-16-34-15-24(29(25)39)19-3-5-20(33)6-4-19/h3-8,13-16,35H,9-12H2,1-2H3,(H,34,39)(H,36,41)(H,37,40)/b23-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056144 (CHEMBL3329671) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1cc2NC(=O)\C(=C/c3[nH]c(C)c(CCC(O)=O)c3C)c2cc1F Show InChI InChI=1S/C27H25FN4O6/c1-13-17(8-9-24(33)34)14(2)29-21(13)11-19-18-10-20(28)23(12-22(18)30-26(19)36)31-27(37)32-25(35)15-4-6-16(38-3)7-5-15/h4-7,10-12,29H,8-9H2,1-3H3,(H,30,36)(H,33,34)(H2,31,32,35,37)/b19-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056141 (CHEMBL3329674) Show SMILES COc1ccc(C(=O)NC(=O)Nc2cc3NC(=O)\C(=C/c4[nH]c(C)c(C(O)=O)c4C)c3cc2F)c(F)c1 Show InChI InChI=1S/C25H20F2N4O6/c1-10-18(28-11(2)21(10)24(34)35)8-15-14-7-17(27)20(9-19(14)29-23(15)33)30-25(36)31-22(32)13-5-4-12(37-3)6-16(13)26/h4-9,28H,1-3H3,(H,29,33)(H,34,35)(H2,30,31,32,36)/b15-8-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50056198 (CHEMBL3329683) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)NC(=O)c4ccc(OC)cc4F)ccc23)c1C Show InChI InChI=1S/C31H35FN6O5/c1-6-38(7-2)13-12-33-30(41)27-17(3)25(34-18(27)4)16-23-21-10-8-19(14-26(21)36-29(23)40)35-31(42)37-28(39)22-11-9-20(43-5)15-24(22)32/h8-11,14-16,34H,6-7,12-13H2,1-5H3,(H,33,41)(H,36,40)(H2,35,37,39,42)/b23-16-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50052072 (CHEMBL3322592) Show SMILES COc1ccc(cc1)-c1c[nH]cc(C(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)c1=O Show InChI InChI=1S/C29H24N4O6/c1-14-23(31-15(2)25(14)29(37)38)11-20-19-9-6-17(10-24(19)33-27(20)35)32-28(36)22-13-30-12-21(26(22)34)16-4-7-18(39-3)8-5-16/h4-13,31H,1-3H3,(H,30,34)(H,32,36)(H,33,35)(H,37,38)/b20-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056187 (CHEMBL3329655) Show SMILES O=C(NC(=O)c1ccccc1)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C21H16N4O3/c26-19(13-5-2-1-3-6-13)25-21(28)23-15-8-9-16-17(11-14-7-4-10-22-14)20(27)24-18(16)12-15/h1-12,22H,(H,24,27)(H2,23,25,26,28)/b17-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50051941 (CHEMBL3322565) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C26H24N4O6/c1-13-20(27-14(2)24(13)26(34)35)11-19-18-9-6-16(10-21(18)30-25(19)33)29-23(32)12-22(31)28-15-4-7-17(36-3)8-5-15/h4-11,27H,12H2,1-3H3,(H,28,31)(H,29,32)(H,30,33)(H,34,35)/b19-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50051941 (CHEMBL3322565) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C26H24N4O6/c1-13-20(27-14(2)24(13)26(34)35)11-19-18-9-6-16(10-21(18)30-25(19)33)29-23(32)12-22(31)28-15-4-7-17(36-3)8-5-15/h4-11,27H,12H2,1-3H3,(H,28,31)(H,29,32)(H,30,33)(H,34,35)/b19-11-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056186 (CHEMBL3329656) Show SMILES Clc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C21H15ClN4O3/c22-13-5-3-12(4-6-13)19(27)26-21(29)24-15-7-8-16-17(10-14-2-1-9-23-14)20(28)25-18(16)11-15/h1-11,23H,(H,25,28)(H2,24,26,27,29)/b17-10-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056184 (CHEMBL3329658) Show SMILES Fc1ccccc1C(=O)NC(=O)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C21H15FN4O3/c22-17-6-2-1-5-15(17)19(27)26-21(29)24-13-7-8-14-16(10-12-4-3-9-23-12)20(28)25-18(14)11-13/h1-11,23H,(H,25,28)(H2,24,26,27,29)/b16-10-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50051942 (CHEMBL3322563) Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056198 (CHEMBL3329683) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)NC(=O)c4ccc(OC)cc4F)ccc23)c1C Show InChI InChI=1S/C31H35FN6O5/c1-6-38(7-2)13-12-33-30(41)27-17(3)25(34-18(27)4)16-23-21-10-8-19(14-26(21)36-29(23)40)35-31(42)37-28(39)22-11-9-20(43-5)15-24(22)32/h8-11,14-16,34H,6-7,12-13H2,1-5H3,(H,33,41)(H,36,40)(H2,35,37,39,42)/b23-16-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056185 (CHEMBL3329657) Show SMILES Clc1ccc(cc1Cl)C(=O)NC(=O)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C21H14Cl2N4O3/c22-16-6-3-11(8-17(16)23)19(28)27-21(30)25-13-4-5-14-15(9-12-2-1-7-24-12)20(29)26-18(14)10-13/h1-10,24H,(H,26,29)(H2,25,27,28,30)/b15-9-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50051941 (CHEMBL3322565) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(O)=O)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C26H24N4O6/c1-13-20(27-14(2)24(13)26(34)35)11-19-18-9-6-16(10-21(18)30-25(19)33)29-23(32)12-22(31)28-15-4-7-17(36-3)8-5-15/h4-11,27H,12H2,1-3H3,(H,28,31)(H,29,32)(H,30,33)(H,34,35)/b19-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50051940 (CHEMBL3322572) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1=O Show InChI InChI=1S/C25H17FN4O3/c26-15-5-8-18(9-6-15)30-12-2-4-20(25(30)33)23(31)28-17-7-10-19-21(13-16-3-1-11-27-16)24(32)29-22(19)14-17/h1-14,27H,(H,28,31)(H,29,32)/b21-13-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50052032 (CHEMBL3322584) Show SMILES COc1ccc(cc1)-c1c[nH]cc(C(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1=O Show InChI InChI=1S/C26H20N4O4/c1-34-18-7-4-15(5-8-18)21-13-27-14-22(24(21)31)26(33)29-17-6-9-19-20(11-16-3-2-10-28-16)25(32)30-23(19)12-17/h2-14,28H,1H3,(H,27,31)(H,29,33)(H,30,32)/b20-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50056142 (CHEMBL3329673) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(CCC(O)=O)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C27H25FN4O6/c1-13-17(8-9-24(33)34)14(2)29-22(13)12-20-18-6-4-15(10-23(18)31-26(20)36)30-27(37)32-25(35)19-7-5-16(38-3)11-21(19)28/h4-7,10-12,29H,8-9H2,1-3H3,(H,31,36)(H,33,34)(H2,30,32,35,37)/b20-12-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50051942 (CHEMBL3322563) Show SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C22H17FN4O3/c23-13-3-5-14(6-4-13)25-20(28)12-21(29)26-16-7-8-17-18(10-15-2-1-9-24-15)22(30)27-19(17)11-16/h1-11,24H,12H2,(H,25,28)(H,26,29)(H,27,30)/b18-10-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50052023 (CHEMBL3322581) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)ccc23)c(C)c1C(O)=O Show InChI InChI=1S/C28H21FN4O5/c1-14-22(30-15(2)24(14)28(37)38)13-21-19-10-7-17(12-23(19)32-26(21)35)31-25(34)20-4-3-11-33(27(20)36)18-8-5-16(29)6-9-18/h3-13,30H,1-2H3,(H,31,34)(H,32,35)(H,37,38)/b21-13-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056197 (CHEMBL3329682) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN(C)C)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C29H31FN6O5/c1-15-23(32-16(2)25(15)28(39)31-10-11-36(3)4)14-21-19-8-6-17(12-24(19)34-27(21)38)33-29(40)35-26(37)20-9-7-18(41-5)13-22(20)30/h6-9,12-14,32H,10-11H2,1-5H3,(H,31,39)(H,34,38)(H2,33,35,37,40)/b21-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50051957 (CHEMBL3322566) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C32H36N6O5/c1-19-26(34-20(2)30(19)32(42)33-12-15-38-13-4-5-14-38)17-25-24-11-8-22(16-27(24)37-31(25)41)36-29(40)18-28(39)35-21-6-9-23(43-3)10-7-21/h6-11,16-17,34H,4-5,12-15,18H2,1-3H3,(H,33,42)(H,35,39)(H,36,40)(H,37,41)/b25-17-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using KKKSPGEYVNIEFG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50052026 (CHEMBL3322582) Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3cc(NC(=O)c4cccn(C)c4=O)ccc23)c(C)c1C(O)=O Show InChI InChI=1S/C23H20N4O5/c1-11-17(24-12(2)19(11)23(31)32)10-16-14-7-6-13(9-18(14)26-21(16)29)25-20(28)15-5-4-8-27(3)22(15)30/h4-10,24H,1-3H3,(H,25,28)(H,26,29)(H,31,32)/b16-10-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50056199 (CHEMBL3329684) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN5CCCC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C31H33FN6O5/c1-17-25(34-18(2)27(17)30(41)33-10-13-38-11-4-5-12-38)16-23-21-8-6-19(14-26(21)36-29(23)40)35-31(42)37-28(39)22-9-7-20(43-3)15-24(22)32/h6-9,14-16,34H,4-5,10-13H2,1-3H3,(H,33,41)(H,36,40)(H2,35,37,39,42)/b23-16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin)				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056189 (CHEMBL3329652) Show SMILES COc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C22H18N4O4/c1-30-16-7-4-13(5-8-16)20(27)26-22(29)24-15-6-9-17-18(11-14-3-2-10-23-14)21(28)25-19(17)12-15/h2-12,23H,1H3,(H,25,28)(H2,24,26,27,29)/b18-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056178 (CHEMBL3329660) Show SMILES FC(F)(F)c1cc(ccc1Cl)C(=O)NC(=O)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C22H14ClF3N4O3/c23-17-6-3-11(8-16(17)22(24,25)26)19(31)30-21(33)28-13-4-5-14-15(9-12-2-1-7-27-12)20(32)29-18(14)10-13/h1-10,27H,(H,29,32)(H2,28,30,31,33)/b15-9-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056196 (CHEMBL3329681) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(CCC(=O)N5CCOCC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C31H32FN5O6/c1-17-21(8-9-28(38)37-10-12-43-13-11-37)18(2)33-26(17)16-24-22-6-4-19(14-27(22)35-30(24)40)34-31(41)36-29(39)23-7-5-20(42-3)15-25(23)32/h4-7,14-16,33H,8-13H2,1-3H3,(H,35,40)(H2,34,36,39,41)/b24-16-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50056197 (CHEMBL3329682) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)NCCN(C)C)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C29H31FN6O5/c1-15-23(32-16(2)25(15)28(39)31-10-11-36(3)4)14-21-19-8-6-17(12-24(19)34-27(21)38)33-29(40)35-26(37)20-9-7-18(41-5)13-22(20)30/h6-9,12-14,32H,10-11H2,1-5H3,(H,31,39)(H,34,38)(H2,33,35,37,40)/b21-14-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50056140 (CHEMBL3329675) Show SMILES COc1ccc(C(=O)NC(=O)Nc2cc3NC(=O)\C(=C/c4[nH]c(C)c(CCC(O)=O)c4C)c3cc2F)c(F)c1 Show InChI InChI=1S/C27H24F2N4O6/c1-12-15(6-7-24(34)35)13(2)30-21(12)10-18-17-9-20(29)23(11-22(17)31-26(18)37)32-27(38)33-25(36)16-5-4-14(39-3)8-19(16)28/h4-5,8-11,30H,6-7H2,1-3H3,(H,31,37)(H,34,35)(H2,32,33,36,38)/b18-10-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using EAIYAAPFAKKK substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056195 (CHEMBL3329680) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(C(=O)N5CCOCC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C29H28FN5O6/c1-15-23(31-16(2)25(15)28(38)35-8-10-41-11-9-35)14-21-19-6-4-17(12-24(19)33-27(21)37)32-29(39)34-26(36)20-7-5-18(40-3)13-22(20)30/h4-7,12-14,31H,8-11H2,1-3H3,(H,33,37)(H2,32,34,36,39)/b21-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50051943 (CHEMBL3322564) Show SMILES COc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1 Show InChI InChI=1S/C23H20N4O4/c1-31-17-7-4-14(5-8-17)25-21(28)13-22(29)26-16-6-9-18-19(11-15-3-2-10-24-15)23(30)27-20(18)12-16/h2-12,24H,13H2,1H3,(H,25,28)(H,26,29)(H,27,30)/b19-11-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assay				Eur J Med Chem 84: 312-34 (2014) Article DOI: 10.1016/j.ejmech.2014.07.033 BindingDB Entry DOI: 10.7270/Q2RV0QB7
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056194 (CHEMBL3329679) Show SMILES COc1ccc(C(=O)NC(=O)Nc2ccc3\C(=C\c4[nH]c(C)c(CCC(=O)N5CCN(C)CC5)c4C)C(=O)Nc3c2)c(F)c1 Show InChI InChI=1S/C32H35FN6O5/c1-18-22(9-10-29(40)39-13-11-38(3)12-14-39)19(2)34-27(18)17-25-23-7-5-20(15-28(23)36-31(25)42)35-32(43)37-30(41)24-8-6-21(44-4)16-26(24)33/h5-8,15-17,34H,9-14H2,1-4H3,(H,36,42)(H2,35,37,41,43)/b25-17-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50056158 (CHEMBL3329661) Show SMILES Cc1ccc(cc1)C(=O)NC(=O)Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1 Show InChI InChI=1S/C22H18N4O3/c1-13-4-6-14(7-5-13)20(27)26-22(29)24-16-8-9-17-18(11-15-3-2-10-23-15)21(28)25-19(17)12-16/h2-12,23H,1H3,(H,25,28)(H2,24,26,27,29)/b18-11-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin) using HLRRASLG substrate				Eur J Med Chem 85: 268-88 (2014) Article DOI: 10.1016/j.ejmech.2014.07.108 BindingDB Entry DOI: 10.7270/Q2028T6Z
					More data for this Ligand-Target Pair

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