Compile Data Set for Download or QSAR

Found 817 hits with Last Name = 'duckett' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577925 (CHEMBL4846565) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577932 (CHEMBL4853982) Show SMILES Cl.CCOCCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577931 (CHEMBL4863751) Show SMILES Cl.CCN(Cc1ccc(cc1)-c1cn[nH]c1)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577917 (CHEMBL4874860) Show SMILES Cl.CC(C)c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577920 (CHEMBL4857780) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccccc1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577916 (CHEMBL4851887) Show SMILES Cl.CC(C)N(Cc1ccc(cc1)C(C)C)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577919 (CHEMBL4869003) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)C1CCCCC1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577921 (CHEMBL4860362) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccsc1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577912 (CHEMBL4852661) Show SMILES Cl.CC(C)c1ccc(CNC(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577927 (CHEMBL4876911) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccn[nH]1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577925 (CHEMBL4846565) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin R1C domain (138 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-termi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577915 (CHEMBL4852707) Show SMILES Cl.CCN(Cc1ccc(cc1)C(C)C)C(=O)[C@@H]1CCCN(C1)c1cccc(OC(C)(C)C(=O)N2CCNCC2)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577918 (CHEMBL4869538) Show SMILES Cl.CC(C)(C)c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577911 (CHEMBL4862286) Show SMILES Cl.CC(C)c1ccc(CN(C)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577929 (CHEMBL4847343) Show SMILES CN1CCN(CC1)C(=O)C(C)(C)Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577926 (CHEMBL4871689) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577930 (CHEMBL4855433) Show SMILES CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cn[nH]c1)C1CC1)C(=O)N1CCCCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577913 (CHEMBL4873635) Show SMILES CC(C)c1ccc(CNC(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(O)=O)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577922 (CHEMBL4869034) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccccn1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577923 (CHEMBL4868531) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1cccnc1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577928 (CHEMBL4864467) Show SMILES Cl.Cn1cc(cn1)-c1ccc(CN(C2CC2)C(=O)[C@@H]2CCCN(C2)c2cccc(OC(C)(C)C(=O)N3CCNCC3)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577924 (CHEMBL4858087) Show SMILES Cl.CC(C)(Oc1cccc(c1)N1CCC[C@H](C1)C(=O)N(Cc1ccc(cc1)-c1ccncc1)C1CC1)C(=O)N1CCNCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
B-cell CLL/lymphoma 9 protein (Homo sapiens)	BDBM50577914 (CHEMBL4868665) Show SMILES CC(C)c1ccc(CNC(=O)[C@H]2CCCN(C2)c2cccc(OC(C)(C)C(O)=O)c2)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-N-terminal biotinyla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00742 BindingDB Entry DOI: 10.7270/Q2SN0DSK
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311713 (CHEMBL1080279 | N-(2-(dimethylamino)ethyl)-N-(3-me...) Show SMILES COc1cccc(CN(CCN(C)C)C(=O)c2nc3ccc(cc3s2)-c2cn[nH]c2)c1 Show InChI InChI=1S/C23H25N5O2S/c1-27(2)9-10-28(15-16-5-4-6-19(11-16)30-3)23(29)22-26-20-8-7-17(12-21(20)31-22)18-13-24-25-14-18/h4-8,11-14H,9-10,15H2,1-3H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311728 (3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)-N-(3-(...) Show SMILES CN(C)CCCNC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1 Show InChI InChI=1S/C25H27N5O2S/c1-30(2)9-3-8-26-24(31)17-5-7-22-18(10-17)11-19(15-32-22)25-29-21-6-4-16(12-23(21)33-25)20-13-27-28-14-20/h4-7,10,12-14,19H,3,8-9,11,15H2,1-2H3,(H,26,31)(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human))	BDBM25004 (3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)C#CCO)-c1nonc1N Show InChI InChI=1S/C16H19N7O3/c1-2-23-14-11(25-8-4-6-17)9-19-10(5-3-7-24)12(14)20-16(23)13-15(18)22-26-21-13/h9,24H,2,4,6-8,17H2,1H3,(H2,18,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-5 (Homo sapiens (Human))	BDBM24994 (4-[1-ethyl-7-(piperidin-4-ylmethoxy)-1H-imidazo[4,...) Show SMILES CCn1c(nc2cncc(OCC3CCNCC3)c12)-c1nonc1N Show InChI InChI=1S/C16H21N7O2/c1-2-23-14-11(20-16(23)13-15(17)22-25-21-13)7-19-8-12(14)24-9-10-3-5-18-6-4-10/h7-8,10,18H,2-6,9H2,1H3,(H2,17,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50495031 (CHEMBL3099975) Show SMILES Oc1onc(c1-c1ccc(F)cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)c1 Show InChI InChI=1S/C24H21FN4O3/c25-18-3-1-16(2-4-18)22-23(28-32-24(22)30)17-9-10-26-21(15-17)27-19-5-7-20(8-6-19)29-11-13-31-14-12-29/h1-10,15,30H,11-14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 (39 to 402 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE3) using biotinylated ATF2 as substrate after 15 min...				Bioorg Med Chem Lett 24: 161-4 (2014) Article DOI: 10.1016/j.bmcl.2013.11.052 BindingDB Entry DOI: 10.7270/Q2XG9V3X
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256436 (CHEMBL481735 | N-(2-(2-(dimethylamino)ethoxy)-4-(1...) Show SMILES CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccc(C)cc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C24H28N4O3/c1-16-4-7-22-18(10-16)11-19(15-31-22)24(29)27-21-6-5-17(20-13-25-26-14-20)12-23(21)30-9-8-28(2)3/h4-7,10,12-14,19H,8-9,11,15H2,1-3H3,(H,25,26)(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25013 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S...) Show SMILES CCn1c(nc2c(ncc(OC[C@H]3CCCNC3)c12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50311728 (3-(6-(1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)-N-(3-(...) Show SMILES CN(C)CCCNC(=O)c1ccc2OCC(Cc2c1)c1nc2ccc(cc2s1)-c1cn[nH]c1 Show InChI InChI=1S/C25H27N5O2S/c1-30(2)9-3-8-26-24(31)17-5-7-22-18(10-17)11-19(15-32-22)25-29-21-6-4-16(12-23(21)33-25)20-13-27-28-14-20/h4-7,10,12-14,19H,3,8-9,11,15H2,1-2H3,(H,26,31)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256384 (6-chloro-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...) Show SMILES COc1cc(NC(=O)C2COc3ccc(Cl)cc3C2)ccc1-c1cn[nH]c1 Show InChI InChI=1S/C20H18ClN3O3/c1-26-19-8-16(3-4-17(19)14-9-22-23-10-14)24-20(25)13-6-12-7-15(21)2-5-18(12)27-11-13/h2-5,7-10,13H,6,11H2,1H3,(H,22,23)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256322 (CHEMBL482336 | N-(2-(2-(dimethylamino)ethoxy)-4-(1...) Show SMILES COc1ccc2OCC(Cc2c1)C(=O)Nc1ccc(cc1OCCN(C)C)-c1cn[nH]c1 Show InChI InChI=1S/C24H28N4O4/c1-28(2)8-9-31-23-12-16(19-13-25-26-14-19)4-6-21(23)27-24(29)18-10-17-11-20(30-3)5-7-22(17)32-15-18/h4-7,11-14,18H,8-10,15H2,1-3H3,(H,25,26)(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25009 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(2-aminoetho...) Show SMILES CCn1c(nc2c(ncc(OCCN)c12)C#CC(C)(C)O)-c1nonc1N Show InChI InChI=1S/C17H21N7O3/c1-4-24-14-11(26-8-7-18)9-20-10(5-6-17(2,3)25)12(14)21-16(24)13-15(19)23-27-22-13/h9,25H,4,7-8,18H2,1-3H3,(H2,19,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25004 (3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)C#CCO)-c1nonc1N Show InChI InChI=1S/C16H19N7O3/c1-2-23-14-11(25-8-4-6-17)9-19-10(5-3-7-24)12(14)20-16(23)13-15(18)22-26-21-13/h9,24H,2,4,6-8,17H2,1H3,(H2,18,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256383 (CHEMBL481545 | N-(2-(2-(dimethylamino)ethoxy)-4-(1...) Show SMILES CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccc(F)cc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C23H25FN4O3/c1-28(2)7-8-30-22-11-15(18-12-25-26-13-18)3-5-20(22)27-23(29)17-9-16-10-19(24)4-6-21(16)31-14-17/h3-6,10-13,17H,7-9,14H2,1-2H3,(H,25,26)(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256067 (CHEMBL481685 | N3-(4-(1H-pyrazol-4-yl)phenyl)-N6-(...) Show SMILES CN(C)CCNC(=O)c1ccc2OCC(Cc2c1)C(=O)Nc1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C24H27N5O3/c1-29(2)10-9-25-23(30)17-5-8-22-18(11-17)12-19(15-32-22)24(31)28-21-6-3-16(4-7-21)20-13-26-27-14-20/h3-8,11,13-14,19H,9-10,12,15H2,1-2H3,(H,25,30)(H,26,27)(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM25472 (CHEMBL519123 | N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-d...) Show SMILES O=C(Nc1ccc(cc1)-c1cn[nH]c1)C1COc2ccccc2O1 Show InChI InChI=1S/C18H15N3O3/c22-18(17-11-23-15-3-1-2-4-16(15)24-17)21-14-7-5-12(6-8-14)13-9-19-20-10-13/h1-10,17H,11H2,(H,19,20)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50246409 (CHEMBL455658 | N-(4-(1H-pyrazol-4-yl)phenyl)-3,4-d...) Show SMILES O=C(Nc1ccc(cc1)-c1cn[nH]c1)C1COc2ccccc2C1 Show InChI InChI=1S/C19H17N3O2/c23-19(15-9-14-3-1-2-4-18(14)24-12-15)22-17-7-5-13(6-8-17)16-10-20-21-11-16/h1-8,10-11,15H,9,12H2,(H,20,21)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256111 (CHEMBL480586 | N-(2-methoxy-4-(1H-pyrazol-4-yl)phe...) Show SMILES COc1cc(ccc1NC(=O)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C20H19N3O3/c1-25-19-9-13(16-10-21-22-11-16)6-7-17(19)23-20(24)15-8-14-4-2-3-5-18(14)26-12-15/h2-7,9-11,15H,8,12H2,1H3,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256068 (6-methoxy-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)c...) Show SMILES COc1ccc2OCC(Cc2c1)C(=O)Nc1ccc(-c2cn[nH]c2)c(OC)c1 Show InChI InChI=1S/C21H21N3O4/c1-26-17-4-6-19-13(8-17)7-14(12-28-19)21(25)24-16-3-5-18(20(9-16)27-2)15-10-22-23-11-15/h3-6,8-11,14H,7,12H2,1-2H3,(H,22,23)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256385 (6-chloro-N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...) Show SMILES COc1cc(ccc1NC(=O)C1COc2ccc(Cl)cc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C20H18ClN3O3/c1-26-19-8-12(15-9-22-23-10-15)2-4-17(19)24-20(25)14-6-13-7-16(21)3-5-18(13)27-11-14/h2-5,7-10,14H,6,11H2,1H3,(H,22,23)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256163 (CHEMBL474425 | N-(2-(2-(dimethylamino)ethoxy)-4-(1...) Show SMILES CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccccc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C23H26N4O3/c1-27(2)9-10-29-22-12-16(19-13-24-25-14-19)7-8-20(22)26-23(28)18-11-17-5-3-4-6-21(17)30-15-18/h3-8,12-14,18H,9-11,15H2,1-2H3,(H,24,25)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM24994 (4-[1-ethyl-7-(piperidin-4-ylmethoxy)-1H-imidazo[4,...) Show SMILES CCn1c(nc2cncc(OCC3CCNCC3)c12)-c1nonc1N Show InChI InChI=1S/C16H21N7O2/c1-2-23-14-11(20-16(23)13-15(17)22-25-21-13)7-19-8-12(14)24-9-10-3-5-18-6-4-10/h7-8,10,18H,2-6,9H2,1H3,(H2,17,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-5 (Homo sapiens (Human))	BDBM24991 (4-(7-{[(3R)-3-aminopyrrolidin-1-yl]carbonyl}-1-eth...) Show SMILES CCn1c(nc2cncc(C(=O)N3CC[C@@H](N)C3)c12)-c1nonc1N |r| Show InChI InChI=1S/C15H18N8O2/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21)/t8-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25016 ((2S)-3-[(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-et...) Show SMILES CCn1c(nc2c(ncc(OCCCNC[C@H](O)CO)c12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C21H29N7O5/c1-4-28-18-15(32-9-5-8-23-10-13(30)12-29)11-24-14(6-7-21(2,3)31)16(18)25-20(28)17-19(22)27-33-26-17/h11,13,23,29-31H,4-5,8-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25014 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3R...) Show SMILES CCn1c(nc2c(ncc(OC[C@@H]3CCCNC3)c12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25010 (4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-[(3S)-3-amin...) Show SMILES CCn1c(nc2c(ncc(OCC[C@@H](N)Cc3ccccc3)c12)C#CC(C)(C)O)-c1nonc1N |r| Show InChI InChI=1S/C25H29N7O3/c1-4-32-22-19(34-13-11-17(26)14-16-8-6-5-7-9-16)15-28-18(10-12-25(2,3)33)20(22)29-24(32)21-23(27)31-35-30-21/h5-9,15,17,33H,4,11,13-14,26H2,1-3H3,(H2,27,31)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256166 (CHEMBL475601 | N-(4-(1H-pyrazol-4-yl)phenyl)-6-met...) Show SMILES COc1ccc2OCC(Cc2c1)C(=O)Nc1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C20H19N3O3/c1-25-18-6-7-19-14(9-18)8-15(12-26-19)20(24)23-17-4-2-13(3-5-17)16-10-21-22-11-16/h2-7,9-11,15H,8,12H2,1H3,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256382 (6-fluoro-N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...) Show SMILES COc1cc(ccc1NC(=O)C1COc2ccc(F)cc2C1)-c1cn[nH]c1 Show InChI InChI=1S/C20H18FN3O3/c1-26-19-8-12(15-9-22-23-10-15)2-4-17(19)24-20(25)14-6-13-7-16(21)3-5-18(13)27-11-14/h2-5,7-10,14H,6,11H2,1H3,(H,22,23)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair

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