Found 119 hits with Last Name = 'duveau' and Initial = 'dy' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50425387
(CHEMBL2311806)Show SMILES Cc1cn(cn1)-c1cc(C)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C28H25N7O/c1-18-11-23(14-24(12-18)35-16-20(3)31-17-35)32-27(36)21-7-6-19(2)26(13-21)34-28-30-10-8-25(33-28)22-5-4-9-29-15-22/h4-17H,1-3H3,(H,32,36)(H,30,33,34) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50425385
(CHEMBL2311807)Show SMILES Cc1cn(cn1)-c1cc(F)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C27H22FN7O/c1-17-5-6-19(10-25(17)34-27-30-9-7-24(33-27)20-4-3-8-29-14-20)26(36)32-22-11-21(28)12-23(13-22)35-15-18(2)31-16-35/h3-16H,1-2H3,(H,32,36)(H,30,33,34) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445521
(CHEMBL3103033 | US11345702, Table 1.21 | US2023039...)Show InChI InChI=1S/C19H18ClN3O/c20-15-5-4-6-16(12-15)23-13-21-17-11-14(7-8-18(17)23)19(24)22-9-2-1-3-10-22/h4-8,11-13H,1-3,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50237710
(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
Discoidin domain-containing receptor 2
(Homo sapiens (Human)) | BDBM50425387
(CHEMBL2311806)Show SMILES Cc1cn(cn1)-c1cc(C)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C28H25N7O/c1-18-11-23(14-24(12-18)35-16-20(3)31-17-35)32-27(36)21-7-6-19(2)26(13-21)34-28-30-10-8-25(33-28)22-5-4-9-29-15-22/h4-17H,1-3H3,(H,32,36)(H,30,33,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445516
(CHEMBL3103038)Show InChI InChI=1S/C20H21N3O/c1-15-5-8-17(9-6-15)23-14-21-18-13-16(7-10-19(18)23)20(24)22-11-3-2-4-12-22/h5-10,13-14H,2-4,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM30884
(1-(3-methylphenyl)-5-(piperidin-1-ylcarbonyl)-1H-b...)Show InChI InChI=1S/C20H21N3O/c1-15-6-5-7-17(12-15)23-14-21-18-13-16(8-9-19(18)23)20(24)22-10-3-2-4-11-22/h5-9,12-14H,2-4,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445520
(CHEMBL3103034)Show InChI InChI=1S/C20H21N3O2/c1-25-17-7-5-6-16(13-17)23-14-21-18-12-15(8-9-19(18)23)20(24)22-10-3-2-4-11-22/h5-9,12-14H,2-4,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445514
(CHEMBL3103040 | US11345702, Table 1.33 | US2023039...)Show InChI InChI=1S/C20H21N3O2/c1-25-17-8-6-16(7-9-17)23-14-21-18-13-15(5-10-19(18)23)20(24)22-11-3-2-4-12-22/h5-10,13-14H,2-4,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445562
(CHEMBL3102994)Show SMILES Cc1cc(c(C)n1-c1ccc(Cl)c(Cl)c1)-c1nnc2CCCCCn12 Show InChI InChI=1S/C19H20Cl2N4/c1-12-10-15(19-23-22-18-6-4-3-5-9-24(18)19)13(2)25(12)14-7-8-16(20)17(21)11-14/h7-8,10-11H,3-6,9H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445523
(CHEMBL3103032)Show InChI InChI=1S/C19H19N3O/c23-19(21-11-5-2-6-12-21)15-9-10-18-17(13-15)20-14-22(18)16-7-3-1-4-8-16/h1,3-4,7-10,13-14H,2,5-6,11-12H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445515
(CHEMBL3103039)Show InChI InChI=1S/C19H18ClN3O/c20-15-5-7-16(8-6-15)23-13-21-17-12-14(4-9-18(17)23)19(24)22-10-2-1-3-11-22/h4-9,12-13H,1-3,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445537
(CHEMBL3103018)Show SMILES CC1CCCN(C1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1 Show InChI InChI=1S/C21H23N3O/c1-15-5-3-7-18(11-15)24-14-22-19-12-17(8-9-20(19)24)21(25)23-10-4-6-16(2)13-23/h3,5,7-9,11-12,14,16H,4,6,10,13H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50425385
(CHEMBL2311807)Show SMILES Cc1cn(cn1)-c1cc(F)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C27H22FN7O/c1-17-5-6-19(10-25(17)34-27-30-9-7-24(33-27)20-4-3-8-29-14-20)26(36)32-22-11-21(28)12-23(13-22)35-15-18(2)31-16-35/h3-16H,1-2H3,(H,32,36)(H,30,33,34) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445522
(CHEMBL3102860)Show InChI InChI=1S/C20H21N3O2/c1-25-19-8-4-3-7-18(19)23-14-21-16-13-15(9-10-17(16)23)20(24)22-11-5-2-6-12-22/h3-4,7-10,13-14H,2,5-6,11-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50425386
(CHEMBL2311808)Show SMILES Cc1cn(cn1)-c1cccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C27H23N7O/c1-18-8-9-20(26(35)31-22-6-3-7-23(14-22)34-16-19(2)30-17-34)13-25(18)33-27-29-12-10-24(32-27)21-5-4-11-28-15-21/h3-17H,1-2H3,(H,31,35)(H,29,32,33) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445555
(CHEMBL3103000)Show InChI InChI=1S/C20H24N4/c1-14-8-10-17(11-9-14)24-15(2)13-18(16(24)3)20-22-21-19-7-5-4-6-12-23(19)20/h8-11,13H,4-7,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445511
(CHEMBL3103043)Show InChI InChI=1S/C17H23N3O/c1-17(2,3)20-12-18-14-11-13(7-8-15(14)20)16(21)19-9-5-4-6-10-19/h7-8,11-12H,4-6,9-10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445561
(CHEMBL3102995)Show InChI InChI=1S/C19H21ClN4/c1-13-11-17(14(2)24(13)16-8-6-7-15(20)12-16)19-22-21-18-9-4-3-5-10-23(18)19/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445549
(CHEMBL3103006)Show SMILES CCOC(=O)c1ccc(cc1)-n1c(C)cc(c1C)-c1nnc2CCCCCn12 Show InChI InChI=1S/C22H26N4O2/c1-4-28-22(27)17-9-11-18(12-10-17)26-15(2)14-19(16(26)3)21-24-23-20-8-6-5-7-13-25(20)21/h9-12,14H,4-8,13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445560
(CHEMBL3102996)Show InChI InChI=1S/C19H21ClN4/c1-13-12-17(14(2)24(13)16-9-7-15(20)8-10-16)19-22-21-18-6-4-3-5-11-23(18)19/h7-10,12H,3-6,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445557
(CHEMBL3102998)Show SMILES Cc1cc(c(C)n1-c1cccc(c1)C(F)(F)F)-c1nnc2CCCCCn12 Show InChI InChI=1S/C20H21F3N4/c1-13-11-17(19-25-24-18-9-4-3-5-10-26(18)19)14(2)27(13)16-8-6-7-15(12-16)20(21,22)23/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445519
(CHEMBL3103035)Show SMILES FC(F)(F)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H18F3N3O/c21-20(22,23)15-5-4-6-16(12-15)26-13-24-17-11-14(7-8-18(17)26)19(27)25-9-2-1-3-10-25/h4-8,11-13H,1-3,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445535
(CHEMBL3103020)Show SMILES CC(C)C1CCCN(C1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1 Show InChI InChI=1S/C23H27N3O/c1-16(2)19-7-5-11-25(14-19)23(27)18-9-10-22-21(13-18)24-15-26(22)20-8-4-6-17(3)12-20/h4,6,8-10,12-13,15-16,19H,5,7,11,14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445559
(CHEMBL3102997)Show InChI InChI=1S/C19H21BrN4/c1-13-12-17(14(2)24(13)16-9-7-15(20)8-10-16)19-22-21-18-6-4-3-5-11-23(18)19/h7-10,12H,3-6,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50347949
(CHEMBL599406 | US8637558, 46)Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1 |w:7.8,t:1| Show InChI InChI=1S/C18H21NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of PGDH (unknown origin) |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445563
(CHEMBL1408258)Show InChI InChI=1S/C19H22N4/c1-14-13-17(15(2)23(14)16-9-5-3-6-10-16)19-21-20-18-11-7-4-8-12-22(18)19/h3,5-6,9-10,13H,4,7-8,11-12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445512
(CHEMBL3103042)Show SMILES CC(C)(C)c1ccc(cc1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C23H27N3O/c1-23(2,3)18-8-10-19(11-9-18)26-16-24-20-15-17(7-12-21(20)26)22(27)25-13-5-4-6-14-25/h7-12,15-16H,4-6,13-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50425387
(CHEMBL2311806)Show SMILES Cc1cn(cn1)-c1cc(C)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C28H25N7O/c1-18-11-23(14-24(12-18)35-16-20(3)31-17-35)32-27(36)21-7-6-19(2)26(13-21)34-28-30-10-8-25(33-28)22-5-4-9-29-15-22/h4-17H,1-3H3,(H,32,36)(H,30,33,34) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50237710
(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445510
(CHEMBL3103044)Show InChI InChI=1S/C17H23N3O/c1-2-3-9-20-13-18-15-12-14(7-8-16(15)20)17(21)19-10-5-4-6-11-19/h7-8,12-13H,2-6,9-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445518
(CHEMBL3103036)Show SMILES CC(C)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C22H25N3O/c1-16(2)17-7-6-8-19(13-17)25-15-23-20-14-18(9-10-21(20)25)22(26)24-11-4-3-5-12-24/h6-10,13-16H,3-5,11-12H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445533
(CHEMBL3103022)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCC(C1)C(F)(F)F Show InChI InChI=1S/C21H20F3N3O/c1-14-4-2-6-17(10-14)27-13-25-18-11-15(7-8-19(18)27)20(28)26-9-3-5-16(12-26)21(22,23)24/h2,4,6-8,10-11,13,16H,3,5,9,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445534
(CHEMBL3103021)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCC(C)(C)C1 Show InChI InChI=1S/C22H25N3O/c1-16-6-4-7-18(12-16)25-15-23-19-13-17(8-9-20(19)25)21(26)24-11-5-10-22(2,3)14-24/h4,6-9,12-13,15H,5,10-11,14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445556
(CHEMBL3102999)Show SMILES Cc1cc(c(C)n1-c1ccc(cc1)C(F)(F)F)-c1nnc2CCCCCn12 Show InChI InChI=1S/C20H21F3N4/c1-13-12-17(19-25-24-18-6-4-3-5-11-26(18)19)14(2)27(13)16-9-7-15(8-10-16)20(21,22)23/h7-10,12H,3-6,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445554
(CHEMBL3103001)Show InChI InChI=1S/C20H21N5/c1-14-11-18(20-23-22-19-9-4-3-5-10-24(19)20)15(2)25(14)17-8-6-7-16(12-17)13-21/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445532
(CHEMBL3103023)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCC(Br)CC1 Show InChI InChI=1S/C20H20BrN3O/c1-14-3-2-4-17(11-14)24-13-22-18-12-15(5-6-19(18)24)20(25)23-9-7-16(21)8-10-23/h2-6,11-13,16H,7-10H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50425386
(CHEMBL2311808)Show SMILES Cc1cn(cn1)-c1cccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C27H23N7O/c1-18-8-9-20(26(35)31-22-6-3-7-23(14-22)34-16-19(2)30-17-34)13-25(18)33-27-29-12-10-24(32-27)21-5-4-11-28-15-21/h3-17H,1-2H3,(H,31,35)(H,29,32,33) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445552
(CHEMBL3103003)Show InChI InChI=1S/C20H24N4O/c1-14-13-18(20-22-21-19-7-5-4-6-12-23(19)20)15(2)24(14)16-8-10-17(25-3)11-9-16/h8-11,13H,4-7,12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445513
(CHEMBL3103041)Show SMILES FC(F)(F)c1ccc(cc1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H18F3N3O/c21-20(22,23)15-5-7-16(8-6-15)26-13-24-17-12-14(4-9-18(17)26)19(27)25-10-2-1-3-11-25/h4-9,12-13H,1-3,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445553
(CHEMBL3103002)Show InChI InChI=1S/C20H21N5/c1-14-12-18(20-23-22-19-6-4-3-5-11-24(19)20)15(2)25(14)17-9-7-16(13-21)8-10-17/h7-10,12H,3-6,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445545
(CHEMBL3103010)Show SMILES Cc1cc(c(C)n1-c1cccc2ccccc12)-c1nnc2CCCCCn12 |(30.03,-40.3,;31.5,-39.83,;32.74,-40.74,;33.99,-39.84,;33.52,-38.37,;34.43,-37.13,;31.98,-38.36,;31.24,-37.01,;29.71,-36.99,;28.96,-35.65,;29.76,-34.32,;31.3,-34.35,;32.09,-33.05,;33.62,-33.07,;34.36,-34.42,;33.57,-35.73,;32.04,-35.7,;35.45,-40.32,;35.92,-41.78,;37.46,-41.78,;37.95,-40.31,;39.45,-39.89,;40.05,-38.45,;39.3,-37.09,;37.77,-36.82,;36.61,-37.85,;36.69,-39.41,)| Show InChI InChI=1S/C23H24N4/c1-16-15-20(23-25-24-22-13-4-3-7-14-26(22)23)17(2)27(16)21-12-8-10-18-9-5-6-11-19(18)21/h5-6,8-12,15H,3-4,7,13-14H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445551
(CHEMBL3103004)Show SMILES Cc1cc(c(C)n1-c1ccc(cc1)[N+]([O-])=O)-c1nnc2CCCCCn12 Show InChI InChI=1S/C19H21N5O2/c1-13-12-17(19-21-20-18-6-4-3-5-11-22(18)19)14(2)23(13)15-7-9-16(10-8-15)24(25)26/h7-10,12H,3-6,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Lck
(Homo sapiens (Human)) | BDBM50237710
(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50425385
(CHEMBL2311807)Show SMILES Cc1cn(cn1)-c1cc(F)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C27H22FN7O/c1-17-5-6-19(10-25(17)34-27-30-9-7-24(33-27)20-4-3-8-29-14-20)26(36)32-22-11-21(28)12-23(13-22)35-15-18(2)31-16-35/h3-16H,1-2H3,(H,32,36)(H,30,33,34) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445558
(CHEMBL2132150)Show InChI InChI=1S/C19H21FN4/c1-13-12-17(14(2)24(13)16-9-7-15(20)8-10-16)19-22-21-18-6-4-3-5-11-23(18)19/h7-10,12H,3-6,11H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50425387
(CHEMBL2311806)Show SMILES Cc1cn(cn1)-c1cc(C)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C28H25N7O/c1-18-11-23(14-24(12-18)35-16-20(3)31-17-35)32-27(36)21-7-6-19(2)26(13-21)34-28-30-10-8-25(33-28)22-5-4-9-29-15-22/h4-17H,1-3H3,(H,32,36)(H,30,33,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445550
(CHEMBL3103005)Show SMILES Cc1cc(c(C)n1-c1ccc(cc1)C(C)(C)C)-c1nnc2CCCCCn12 Show InChI InChI=1S/C23H30N4/c1-16-15-20(22-25-24-21-9-7-6-8-14-26(21)22)17(2)27(16)19-12-10-18(11-13-19)23(3,4)5/h10-13,15H,6-9,14H2,1-5H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445517
(CHEMBL3103037)Show SMILES CC(C)(C)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C23H27N3O/c1-23(2,3)18-8-7-9-19(15-18)26-16-24-20-14-17(10-11-21(20)26)22(27)25-12-5-4-6-13-25/h7-11,14-16H,4-6,12-13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 171 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this Ligand-Target Pair | |
Discoidin domain-containing receptor 2
(Homo sapiens (Human)) | BDBM50425385
(CHEMBL2311807)Show SMILES Cc1cn(cn1)-c1cc(F)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1 Show InChI InChI=1S/C27H22FN7O/c1-17-5-6-19(10-25(17)34-27-30-9-7-24(33-27)20-4-3-8-29-14-20)26(36)32-22-11-21(28)12-23(13-22)35-15-18(2)31-16-35/h3-16H,1-2H3,(H,32,36)(H,30,33,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrate |
Bioorg Med Chem Lett 23: 682-6 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.111 BindingDB Entry DOI: 10.7270/Q2PK0HG5 |
More data for this Ligand-Target Pair | |