Found 258 hits with Last Name = 'ebner' and Initial = 'dc' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360584
(CHEMBL1933350)Show SMILES CCC[C@@H]([C@@H](c1c[nH]c2c(F)cc(C)cc12)c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O |r| Show InChI InChI=1S/C30H30ClFN2O3/c1-3-4-23(19-5-7-21(8-6-19)30(37)33-14-13-27(35)36)28(20-9-11-22(31)12-10-20)25-17-34-29-24(25)15-18(2)16-26(29)32/h5-12,15-17,23,28,34H,3-4,13-14H2,1-2H3,(H,33,37)(H,35,36)/t23-,28+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360599
(CHEMBL1933365)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)C1CCCC1 Show InChI InChI=1S/C26H27F3N4O3/c27-26(28,29)20-9-11-22(12-10-20)33-16-21(15-31-33)32-24(17-3-1-2-4-17)18-5-7-19(8-6-18)25(36)30-14-13-23(34)35/h5-12,15-17,24,32H,1-4,13-14H2,(H,30,36)(H,34,35) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360599
(CHEMBL1933365)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)C1CCCC1 Show InChI InChI=1S/C26H27F3N4O3/c27-26(28,29)20-9-11-22(12-10-20)33-16-21(15-31-33)32-24(17-3-1-2-4-17)18-5-7-19(8-6-18)25(36)30-14-13-23(34)35/h5-12,15-17,24,32H,1-4,13-14H2,(H,30,36)(H,34,35) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360598
(CHEMBL1933364)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CCC(F)(F)F)Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c25-23(26,27)11-9-20(15-1-3-16(4-2-15)22(37)31-12-10-21(35)36)33-18-13-32-34(14-18)19-7-5-17(6-8-19)24(28,29)30/h1-8,13-14,20,33H,9-12H2,(H,31,37)(H,35,36) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360598
(CHEMBL1933364)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CCC(F)(F)F)Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c25-23(26,27)11-9-20(15-1-3-16(4-2-15)22(37)31-12-10-21(35)36)33-18-13-32-34(14-18)19-7-5-17(6-8-19)24(28,29)30/h1-8,13-14,20,33H,9-12H2,(H,31,37)(H,35,36) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360597
(CHEMBL1933363)Show SMILES CCCC(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H25F3N4O3/c1-2-3-21(16-4-6-17(7-5-16)23(34)28-13-12-22(32)33)30-19-14-29-31(15-19)20-10-8-18(9-11-20)24(25,26)27/h4-11,14-15,21,30H,2-3,12-13H2,1H3,(H,28,34)(H,32,33) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360597
(CHEMBL1933363)Show SMILES CCCC(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H25F3N4O3/c1-2-3-21(16-4-6-17(7-5-16)23(34)28-13-12-22(32)33)30-19-14-29-31(15-19)20-10-8-18(9-11-20)24(25,26)27/h4-11,14-15,21,30H,2-3,12-13H2,1H3,(H,28,34)(H,32,33) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360601
(CHEMBL1933349 | MK-0893)Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C32H27Cl2N3O4/c1-19(20-3-5-21(6-4-20)32(40)35-12-11-31(38)39)37-30(18-29(36-37)25-14-26(33)17-27(34)15-25)24-8-7-23-16-28(41-2)10-9-22(23)13-24/h3-10,13-19H,11-12H2,1-2H3,(H,35,40)(H,38,39)/t19-/m0/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50244455
((R)-3-{4-[1-(4-Cyclohex-1-enylphenyl)-3-(3,5-dichl...)Show SMILES O[C@H](CNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1)C(O)=O |r,t:31| Show InChI InChI=1S/C30H29Cl2N3O5/c31-23-14-24(32)16-25(15-23)34-30(40)35(26-12-10-21(11-13-26)20-4-2-1-3-5-20)18-19-6-8-22(9-7-19)28(37)33-17-27(36)29(38)39/h4,6-16,27,36H,1-3,5,17-18H2,(H,33,37)(H,34,40)(H,38,39)/t27-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360589
(CHEMBL1933355)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(CC)cc1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C25H29N3O4/c1-3-5-23(19-8-10-20(11-9-19)25(31)26-15-14-24(29)30)32-22-16-27-28(17-22)21-12-6-18(4-2)7-13-21/h6-13,16-17,23H,3-5,14-15H2,1-2H3,(H,26,31)(H,29,30) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360598
(CHEMBL1933364)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CCC(F)(F)F)Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c25-23(26,27)11-9-20(15-1-3-16(4-2-15)22(37)31-12-10-21(35)36)33-18-13-32-34(14-18)19-7-5-17(6-8-19)24(28,29)30/h1-8,13-14,20,33H,9-12H2,(H,31,37)(H,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360598
(CHEMBL1933364)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CCC(F)(F)F)Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c25-23(26,27)11-9-20(15-1-3-16(4-2-15)22(37)31-12-10-21(35)36)33-18-13-32-34(14-18)19-7-5-17(6-8-19)24(28,29)30/h1-8,13-14,20,33H,9-12H2,(H,31,37)(H,35,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360600
(CHEMBL1933348)Show SMILES CCCc1c(cc(C(C)C)c(C(C)O)c1-c1ccc(F)cc1)C(C)C Show InChI InChI=1S/C23H31FO/c1-7-8-19-20(14(2)3)13-21(15(4)5)22(16(6)25)23(19)17-9-11-18(24)12-10-17/h9-16,25H,7-8H2,1-6H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 356 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360594
(CHEMBL1933360)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H24F3N3O4/c1-2-3-21(16-4-6-17(7-5-16)23(33)28-13-12-22(31)32)34-20-14-29-30(15-20)19-10-8-18(9-11-19)24(25,26)27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,28,33)(H,31,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360594
(CHEMBL1933360)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H24F3N3O4/c1-2-3-21(16-4-6-17(7-5-16)23(33)28-13-12-22(31)32)34-20-14-29-30(15-20)19-10-8-18(9-11-19)24(25,26)27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,28,33)(H,31,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360588
(CHEMBL1933354)Show SMILES CCCC(Oc1cnn(c1)-c1cccc(CC)c1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C25H29N3O4/c1-3-6-23(19-9-11-20(12-10-19)25(31)26-14-13-24(29)30)32-22-16-27-28(17-22)21-8-5-7-18(4-2)15-21/h5,7-12,15-17,23H,3-4,6,13-14H2,1-2H3,(H,26,31)(H,29,30) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 556 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360591
(CHEMBL1933357)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(Cl)cc1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H24ClN3O4/c1-2-3-21(16-4-6-17(7-5-16)23(30)25-13-12-22(28)29)31-20-14-26-27(15-20)19-10-8-18(24)9-11-19/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360598
(CHEMBL1933364)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CCC(F)(F)F)Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c25-23(26,27)11-9-20(15-1-3-16(4-2-15)22(37)31-12-10-21(35)36)33-18-13-32-34(14-18)19-7-5-17(6-8-19)24(28,29)30/h1-8,13-14,20,33H,9-12H2,(H,31,37)(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 816 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360598
(CHEMBL1933364)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CCC(F)(F)F)Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H22F6N4O3/c25-23(26,27)11-9-20(15-1-3-16(4-2-15)22(37)31-12-10-21(35)36)33-18-13-32-34(14-18)19-7-5-17(6-8-19)24(28,29)30/h1-8,13-14,20,33H,9-12H2,(H,31,37)(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 816 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360599
(CHEMBL1933365)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)C1CCCC1 Show InChI InChI=1S/C26H27F3N4O3/c27-26(28,29)20-9-11-22(12-10-20)33-16-21(15-31-33)32-24(17-3-1-2-4-17)18-5-7-19(8-6-18)25(36)30-14-13-23(34)35/h5-12,15-17,24,32H,1-4,13-14H2,(H,30,36)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 927 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360599
(CHEMBL1933365)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)C1CCCC1 Show InChI InChI=1S/C26H27F3N4O3/c27-26(28,29)20-9-11-22(12-10-20)33-16-21(15-31-33)32-24(17-3-1-2-4-17)18-5-7-19(8-6-18)25(36)30-14-13-23(34)35/h5-12,15-17,24,32H,1-4,13-14H2,(H,30,36)(H,34,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 927 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360587
(CHEMBL1933353)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(C)cc1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H27N3O4/c1-3-4-22(18-7-9-19(10-8-18)24(30)25-14-13-23(28)29)31-21-15-26-27(16-21)20-11-5-17(2)6-12-20/h5-12,15-16,22H,3-4,13-14H2,1-2H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 968 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360590
(CHEMBL1933356)Show SMILES CCCC(Oc1cnn(c1)-c1cccc(Cl)c1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H24ClN3O4/c1-2-4-21(16-7-9-17(10-8-16)23(30)25-12-11-22(28)29)31-20-14-26-27(15-20)19-6-3-5-18(24)13-19/h3,5-10,13-15,21H,2,4,11-12H2,1H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360586
(CHEMBL1933352)Show SMILES CCCC(Oc1cnn(c1)-c1cccc(C)c1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H27N3O4/c1-3-5-22(18-8-10-19(11-9-18)24(30)25-13-12-23(28)29)31-21-15-26-27(16-21)20-7-4-6-17(2)14-20/h4,6-11,14-16,22H,3,5,12-13H2,1-2H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360595
(CHEMBL1933361)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H23F3N4O4/c1-2-3-19(15-4-6-16(7-5-15)22(33)27-11-10-21(31)32)34-18-13-29-30(14-18)20-9-8-17(12-28-20)23(24,25)26/h4-9,12-14,19H,2-3,10-11H2,1H3,(H,27,33)(H,31,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360596
(CHEMBL1933362)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(nc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H23F3N4O4/c1-2-3-19(15-4-6-16(7-5-15)22(33)27-11-10-21(31)32)34-18-13-29-30(14-18)17-8-9-20(28-12-17)23(24,25)26/h4-9,12-14,19H,2-3,10-11H2,1H3,(H,27,33)(H,31,32) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360597
(CHEMBL1933363)Show SMILES CCCC(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H25F3N4O3/c1-2-3-21(16-4-6-17(7-5-16)23(34)28-13-12-22(32)33)30-19-14-29-31(15-19)20-10-8-18(9-11-20)24(25,26)27/h4-11,14-15,21,30H,2-3,12-13H2,1H3,(H,28,34)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360593
(CHEMBL1933359)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(OC)cc1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H27N3O5/c1-3-4-22(17-5-7-18(8-6-17)24(30)25-14-13-23(28)29)32-21-15-26-27(16-21)19-9-11-20(31-2)12-10-19/h5-12,15-16,22H,3-4,13-14H2,1-2H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360592
(CHEMBL1933358)Show SMILES CCCC(Oc1cnn(c1)-c1cccc(OC)c1)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H27N3O5/c1-3-5-22(17-8-10-18(11-9-17)24(30)25-13-12-23(28)29)32-21-15-26-27(16-21)19-6-4-7-20(14-19)31-2/h4,6-11,14-16,22H,3,5,12-13H2,1-2H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360599
(CHEMBL1933365)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)C1CCCC1 Show InChI InChI=1S/C26H27F3N4O3/c27-26(28,29)20-9-11-22(12-10-20)33-16-21(15-31-33)32-24(17-3-1-2-4-17)18-5-7-19(8-6-18)25(36)30-14-13-23(34)35/h5-12,15-17,24,32H,1-4,13-14H2,(H,30,36)(H,34,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360599
(CHEMBL1933365)Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)C1CCCC1 Show InChI InChI=1S/C26H27F3N4O3/c27-26(28,29)20-9-11-22(12-10-20)33-16-21(15-31-33)32-24(17-3-1-2-4-17)18-5-7-19(8-6-18)25(36)30-14-13-23(34)35/h5-12,15-17,24,32H,1-4,13-14H2,(H,30,36)(H,34,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360594
(CHEMBL1933360)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H24F3N3O4/c1-2-3-21(16-4-6-17(7-5-16)23(33)28-13-12-22(31)32)34-20-14-29-30(15-20)19-10-8-18(9-11-19)24(25,26)27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,28,33)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Gastric inhibitory polypeptide receptor
(Homo sapiens (Human)) | BDBM50360594
(CHEMBL1933360)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H24F3N3O4/c1-2-3-21(16-4-6-17(7-5-16)23(33)28-13-12-22(31)32)34-20-14-29-30(15-20)19-10-8-18(9-11-19)24(25,26)27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,28,33)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GIP from human GIPR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360597
(CHEMBL1933363)Show SMILES CCCC(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H25F3N4O3/c1-2-3-21(16-4-6-17(7-5-16)23(34)28-13-12-22(32)33)30-19-14-29-31(15-19)20-10-8-18(9-11-20)24(25,26)27/h4-11,14-15,21,30H,2-3,12-13H2,1H3,(H,28,34)(H,32,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360597
(CHEMBL1933363)Show SMILES CCCC(Nc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H25F3N4O3/c1-2-3-21(16-4-6-17(7-5-16)23(34)28-13-12-22(32)33)30-19-14-29-31(15-19)20-10-8-18(9-11-20)24(25,26)27/h4-11,14-15,21,30H,2-3,12-13H2,1H3,(H,28,34)(H,32,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon receptor
(Homo sapiens (Human)) | BDBM50360585
(CHEMBL1933351)Show SMILES CCCC(Oc1cnn(c1)-c1ccccc1C)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H27N3O4/c1-3-6-22(18-9-11-19(12-10-18)24(30)25-14-13-23(28)29)31-20-15-26-27(16-20)21-8-5-4-7-17(21)2/h4-5,7-12,15-16,22H,3,6,13-14H2,1-2H3,(H,25,30)(H,28,29) | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]Glucagon-Cex from human GCGR |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360594
(CHEMBL1933360)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H24F3N3O4/c1-2-3-21(16-4-6-17(7-5-16)23(33)28-13-12-22(31)32)34-20-14-29-30(15-20)19-10-8-18(9-11-19)24(25,26)27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,28,33)(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50360594
(CHEMBL1933360)Show SMILES CCCC(Oc1cnn(c1)-c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O Show InChI InChI=1S/C24H24F3N3O4/c1-2-3-21(16-4-6-17(7-5-16)23(33)28-13-12-22(31)32)34-20-14-29-30(15-20)19-10-8-18(9-11-19)24(25,26)27/h4-11,14-15,21H,2-3,12-13H2,1H3,(H,28,33)(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]GLP-1 from human GLP1R |
Bioorg Med Chem Lett 22: 415-20 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.113
BindingDB Entry DOI: 10.7270/Q2H70G82 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237939
(US9394285, 20)Show SMILES OC(=O)c1c[nH]c2cc(F)c(c(F)c12)-c1ccc(cc1)C1(O)COC1 Show InChI InChI=1S/C18H13F2NO4/c19-12-5-13-15(11(6-21-13)17(22)23)16(20)14(12)9-1-3-10(4-2-9)18(24)7-25-8-18/h1-6,21,24H,7-8H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 53.6 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237940
(US9394285, 21)Show SMILES CC(C)(CO)COc1ccc(cc1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O Show InChI InChI=1S/C20H20ClNO4/c1-20(2,10-23)11-26-13-5-3-12(4-6-13)14-7-15-16(19(24)25)9-22-18(15)8-17(14)21/h3-9,22-23H,10-11H2,1-2H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 93.5 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237941
(US9394285, 22)Show SMILES OCC1(CC1)c1ccc(cc1)-c1c(F)cc2[nH]cc(C(O)=O)c2c1F Show InChI InChI=1S/C19H15F2NO3/c20-13-7-14-16(12(8-22-14)18(24)25)17(21)15(13)10-1-3-11(4-2-10)19(9-23)5-6-19/h1-4,7-8,22-23H,5-6,9H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 13.7 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237942
(US9394285, 23)Show SMILES OCC1(CC1)c1ccc(cc1)-c1cc2c(c[nH]c2cc1C#N)C(O)=O Show InChI InChI=1S/C20H16N2O3/c21-9-13-7-18-16(17(10-22-18)19(24)25)8-15(13)12-1-3-14(4-2-12)20(11-23)5-6-20/h1-4,7-8,10,22-23H,5-6,11H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237943
(US9394285, 24)Show SMILES OCCOc1ccc(cc1)-c1c(F)cc2[nH]cc(C(O)=O)c2c1F Show InChI InChI=1S/C17H13F2NO4/c18-12-7-13-15(11(8-20-13)17(22)23)16(19)14(12)9-1-3-10(4-2-9)24-6-5-21/h1-4,7-8,20-21H,5-6H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 252 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237944
(US9394285, 25)Show SMILES COc1cc(ccc1C1(O)CCC1)-c1cc2c(c[nH]c2cc1F)C(O)=O Show InChI InChI=1S/C20H18FNO4/c1-26-18-7-11(3-4-15(18)20(25)5-2-6-20)12-8-13-14(19(23)24)10-22-17(13)9-16(12)21/h3-4,7-10,22,25H,2,5-6H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 111 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM60975
(4,6-difluoro-5-[4-(1-hydroxy-2-methylpropan-2-yl)p...)Show SMILES CC(C)(CO)c1ccc(cc1)-c1c(F)cc2[nH]cc(C(O)=O)c2c1F Show InChI InChI=1S/C19H17F2NO3/c1-19(2,9-23)11-5-3-10(4-6-11)15-13(20)7-14-16(17(15)21)12(8-22-14)18(24)25/h3-8,22-23H,9H2,1-2H3,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 125 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237946
(US9394285, 27)Show SMILES Cc1cc2[nH]cc(C(O)=O)c2cc1-c1ccc(cc1)C1(CO)CC1 Show InChI InChI=1S/C20H19NO3/c1-12-8-18-16(17(10-21-18)19(23)24)9-15(12)13-2-4-14(5-3-13)20(11-22)6-7-20/h2-5,8-10,21-22H,6-7,11H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 36.9 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237947
(US9394285, 28)Show SMILES OCCCOc1ccc(cc1)-c1c(F)cc2[nH]cc(C(O)=O)c2c1F Show InChI InChI=1S/C18H15F2NO4/c19-13-8-14-16(12(9-21-14)18(23)24)17(20)15(13)10-2-4-11(5-3-10)25-7-1-6-22/h2-5,8-9,21-22H,1,6-7H2,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 1.08E+3 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237948
(US9394285, 29)Show InChI InChI=1S/C16H12ClNO3/c1-21-10-4-2-3-9(5-10)11-6-12-13(16(19)20)8-18-15(12)7-14(11)17/h2-8,18H,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 383 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237949
(US9394285, 30)Show InChI InChI=1S/C18H16ClNO4/c19-16-9-17-14(15(10-20-17)18(22)23)8-13(16)11-2-4-12(5-3-11)24-7-1-6-21/h2-5,8-10,20-21H,1,6-7H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 30 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human)) | BDBM237950
(US9394285, 31)Show InChI InChI=1S/C17H14ClNO3/c1-2-22-11-5-3-10(4-6-11)12-7-13-14(17(20)21)9-19-16(13)8-15(12)18/h3-9,19H,2H2,1H3,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 130 | n/a | n/a | 7.5 | 25 |
Pfizer Inc.
US Patent
| Assay Description
The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass... |
US Patent US9394285 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80Q7 |
More data for this
Ligand-Target Pair | |
Search and Browse
