Compile Data Set for Download or QSAR

Found 159 hits with Last Name = 'fabis' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399621 (CHEMBL2181166) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399622 (CHEMBL2181168) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399623 (CHEMBL2181169) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399621 (CHEMBL2181166) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399619 (CHEMBL2181189) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50443687 (CHEMBL3093187) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCC(F)(F)F)CC1)c1cccnc21 Show InChI InChI=1S/C22H23F4N3O/c23-18-6-1-4-16-19-17(5-2-10-27-19)21(28-20(16)18)30-14-15-7-12-29(13-8-15)11-3-9-22(24,25)26/h1-2,4-6,10,15H,3,7-9,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399622 (CHEMBL2181168) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399616 (CHEMBL2181188) Show SMILES CCCN1CCC(COc2nc3c(Cl)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210122 (CHEMBL234881 | [2-(2',6'-dimethyl-biphenyl-3-yl)-e...) Show SMILES CN(C)CCc1cccc(c1)-c1c(C)cccc1C Show InChI InChI=1S/C18H23N/c1-14-7-5-8-15(2)18(14)17-10-6-9-16(13-17)11-12-19(3)4/h5-10,13H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399615 (CHEMBL2181171) Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210124 (2-(2'-methyl-biphenyl-3-yl)-ethylamine | CHEMBL234...) Show SMILES Cc1ccccc1-c1cccc(CCN)c1 Show InChI InChI=1S/C15H17N/c1-12-5-2-3-8-15(12)14-7-4-6-13(11-14)9-10-16/h2-8,11H,9-10,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210123 (CHEMBL395870 | N,N-dimethyl-2-(2'-methylbiphenyl-3...) Show SMILES CN(C)CCc1cccc(c1)-c1ccccc1C Show InChI InChI=1S/C17H21N/c1-14-7-4-5-10-17(14)16-9-6-8-15(13-16)11-12-18(2)3/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210126 (CHEMBL232792 | [2-(2'-methoxy-biphenyl-3-yl)-ethyl...) Show SMILES COc1ccccc1-c1cccc(CCN(C)C)c1 Show InChI InChI=1S/C17H21NO/c1-18(2)12-11-14-7-6-8-15(13-14)16-9-4-5-10-17(16)19-3/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210125 (CHEMBL232791 | [2-(2',6'-dimethoxy-biphenyl-3-yl)-...) Show SMILES COc1cccc(OC)c1-c1cccc(CCN(C)C)c1 Show InChI InChI=1S/C18H23NO2/c1-19(2)12-11-14-7-5-8-15(13-14)18-16(20-3)9-6-10-17(18)21-4/h5-10,13H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50443688 (CHEMBL3093186) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCC(F)(F)F)CC1)c1cccnc21 Show InChI InChI=1S/C21H21F4N3O/c22-17-5-1-3-15-18-16(4-2-9-26-18)20(27-19(15)17)29-13-14-6-10-28(11-7-14)12-8-21(23,24)25/h1-5,9,14H,6-8,10-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity to rat 5HT1A				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399615 (CHEMBL2181171) Show SMILES CCCN1CCC(COc2nc3ccccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399623 (CHEMBL2181169) Show SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50443690 (CHEMBL3093184) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCC(F)(F)F)CC1)c1ccccc21 Show InChI InChI=1S/C23H24F4N2O/c24-20-8-3-7-18-17-5-1-2-6-19(17)22(28-21(18)20)30-15-16-9-13-29(14-10-16)12-4-11-23(25,26)27/h1-3,5-8,16H,4,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399620 (CHEMBL2181187) Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 in sf9 cells				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against Human 5-HT7R expressed in sf9 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity to rat 5HT1A				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170159 (2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-p...) Show SMILES COC(=O)c1cccc(C)c1-n1ccc(CN2CCN(CC2)c2ccccc2OC)c1 Show InChI InChI=1S/C25H29N3O3/c1-19-7-6-8-21(25(29)31-3)24(19)28-12-11-20(18-28)17-26-13-15-27(16-14-26)22-9-4-5-10-23(22)30-2/h4-12,18H,13-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT7R expressed in HEK-293 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399619 (CHEMBL2181189) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399619 (CHEMBL2181189) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50170158 (1-(2-Methoxy-phenyl)-4-(1-o-tolyl-1H-pyrrol-3-ylme...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C)CC1 Show InChI InChI=1S/C23H27N3O/c1-19-7-3-4-8-21(19)26-12-11-20(18-26)17-24-13-15-25(16-14-24)22-9-5-6-10-23(22)27-2/h3-12,18H,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT7R expressed in HEK-293 cells				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399633 (CHEMBL2181190) Show SMILES CCCN1CCC(COc2nc3ccccc3c3cccc(F)c23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-21-18(7-5-8-19(21)23)17-6-3-4-9-20(17)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399616 (CHEMBL2181188) Show SMILES CCCN1CCC(COc2nc3c(Cl)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50443691 (CHEMBL3093194) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCC(F)(F)F)CC1)c1ccccc21 Show InChI InChI=1S/C22H22F4N2O/c23-19-7-3-6-17-16-4-1-2-5-18(16)21(27-20(17)19)29-14-15-8-11-28(12-9-15)13-10-22(24,25)26/h1-7,15H,8-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399617 (CHEMBL2181172) Show SMILES CCCN1CCC(COc2nc3ccccc3c3cnccc23)CC1 Show InChI InChI=1S/C21H25N3O/c1-2-11-24-12-8-16(9-13-24)15-25-21-18-7-10-22-14-19(18)17-5-3-4-6-20(17)23-21/h3-7,10,14,16H,2,8-9,11-13,15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50399620 (CHEMBL2181187) Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Binding affinity to human 5HT2B by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399618 (CHEMBL2181185) Show SMILES CCCN1CCC(COc2nc3cc(F)ccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-11-25-12-9-16(10-13-25)15-26-22-20-6-4-3-5-18(20)19-8-7-17(23)14-21(19)24-22/h3-8,14,16H,2,9-13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity against rat 5-HT1A receptor				Bioorg Med Chem Lett 15: 3753-7 (2005) Article DOI: 10.1016/j.bmcl.2005.05.059 BindingDB Entry DOI: 10.7270/Q2BV7G51
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50170156 (2-(3-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-1...) Show SMILES COc1ccccc1N1CCN(Cc2ccn(c2)-c2ccccc2C#N)CC1 Show InChI InChI=1S/C23H24N4O/c1-28-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-19-10-11-27(18-19)21-7-3-2-6-20(21)16-24/h2-11,18H,12-15,17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Caen Curated by ChEMBL					Assay Description Binding affinity to rat 5HT1A				Bioorg Med Chem Lett 17: 3018-22 (2007) Article DOI: 10.1016/j.bmcl.2007.03.054 BindingDB Entry DOI: 10.7270/Q2B857T1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399620 (CHEMBL2181187) Show SMILES CCCN1CCC(COc2nc3c(OC)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50399619 (CHEMBL2181189) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Binding affinity to human 5HT2B by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399632 (CHEMBL2177145) Show SMILES CCCN1CCC(COc2nc3ccccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H26N2O/c1-2-13-24-14-11-17(12-15-24)16-25-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)23-22/h3-10,17H,2,11-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50399632 (CHEMBL2177145) Show SMILES CCCN1CCC(COc2nc3ccccc3c3ccccc23)CC1 Show InChI InChI=1S/C22H26N2O/c1-2-13-24-14-11-17(12-15-24)16-25-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)23-22/h3-10,17H,2,11-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50443689 (CHEMBL3093185) Show SMILES FC(F)CN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C20H20F3N3O/c21-16-5-1-3-14-18-15(4-2-8-24-18)20(25-19(14)16)27-12-13-6-9-26(10-7-13)11-17(22)23/h1-5,8,13,17H,6-7,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southampton Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes				Bioorg Med Chem 21: 7529-38 (2013) Article DOI: 10.1016/j.bmc.2013.08.061 BindingDB Entry DOI: 10.7270/Q2930VN9
					More data for this Ligand-Target Pair

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