Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12255 (AZD0530 | CHEMBL217092 | Compound 33 | N-(5-chloro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12241 (AZD0530 analogue 19 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6219 (BMCL182776 Compound 1 | Chlorobenzodioxole deriv. ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12231 (AZD0530 analogue 9 | N-(2-chloro-5-methoxyphenyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12237 (AZD0530 analogue 15 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6211 (Benzodioxole deriv. 20 | N-(5-Bromo-1,3-benzodioxo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6204 (Benzofuran deriv. 13 | N-(3-Chloro-1-benzofuran-7-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6210 (Benzodioxole deriv. 19 | N-(5-Chloro-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12252 (AZD0530 analogue 30 | N-(5-Chloro-1,3-benzodioxol-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12250 (AZD0530 analogue 28 | N-(5-Chloro-1,3-benzodioxol-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12247 (AZD0530 analogue 25 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12243 (AZD0530 analogue 21 | N-(2-chloro-5-methoxyphenyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174939 (CHEMBL424664 | N-(3-chloro-6-methoxypyridin-2-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6218 (AZD0530 analogue 34 | Chlorobenzodioxole deriv. 27...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6218 (AZD0530 analogue 34 | Chlorobenzodioxole deriv. 27...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12259 (AZD0530 analogue 37 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174932 (CHEMBL197287 | N-(2-chloro-5-methoxypyridin-3-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12253 (AZD0530 analogue 31 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12238 (AZD0530 analogue 16 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12240 (AZD0530 analogue 18 | N-(5-Chloro-1,3-benzodioxol-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174934 (CHEMBL424839 | N-(3-chloro-6-methoxypyridin-2-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174935 (CHEMBL371688 | N-(3-chloro-6-methoxypyridin-2-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174929 (CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12251 (AZD0530 analogue 29 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174936 (1-(4-(2-(4-(3-chloro-6-methoxypyrazin-2-ylamino)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12246 (AZD0530 analogue 24 | N-(5-Chloro-1,3-benzodioxol-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6196 (Methoxy Aniline 5 | N-(2-Chloro-5-methoxyphenyl)-6...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6198 (AZD0530 analogue 35 | M475271 | Methoxy Aniline 7 ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6200 (Benzofuran deriv. 9 | N-(5-Chloro-1-benzofuran-4-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6202 (Benzofuran deriv. 11 | N-(6-Chloro-1-benzofuran-7-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6216 (Benzodioxole deriv. 25 | N-(5-Chloro-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6220 (4-[({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]-6...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | 25 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12228 (AZD0530 analogue 6 | N-(5-chloro-2H-1,3-benzodioxo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6198 (AZD0530 analogue 35 | M475271 | Methoxy Aniline 7 ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174933 (1-(4-(2-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12229 (AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6209 (Benzodioxole deriv. 18 | N-(1,3-Benzodioxol-4-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174937 (CHEMBL198946 | N-(3-chloro-6-methoxypyridin-2-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12258 (AZD0530 analogue 36 | N-(5-chloro-2H-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174942 (1-(4-(2-(4-(5-chloro-2-methoxypyrimidin-4-ylamino)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6199 (Benzofuran deriv. 8 | N-(1-Benzofuran-4-yl)-6-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6208 (Indole deriv. 17 | N-(3-Chloro-1H-indol-7-yl)-6-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174930 (1-(4-(3-(4-(3-chloro-6-methoxypyridin-2-ylamino)-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibition of Src-transfected 3T3 cell proliferation | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50174938 (CHEMBL425209 | N-(3-chloro-6-methoxypyridin-2-yl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against c-Src kinase | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12254 (1-{4-[2-({4-[(5-fluoro-2H-1,3-benzodioxol-4-yl)ami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12230 (AZD0530 analogue 8 | N-(2-chloro-5-methoxyphenyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM12229 (AZD0530 analogue 7 | CHEMBL200217 | N-(2-Chloro-5-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM6212 (Benzodioxole deriv. 21 | N-(5-Fluoro-1,3-benzodiox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob... | J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50174929 (CHEMBL369899 | N-(2-chloro-5-methoxypyridin-3-yl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherches Curated by ChEMBL | Assay Description Inhibitory activity against KDR | Bioorg Med Chem Lett 15: 5446-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.106 BindingDB Entry DOI: 10.7270/Q2765DWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM12232 (AZD0530 analogue 10 | CHEMBL381206 | N-(2-chloro-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca | Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room... | J Med Chem 49: 6465-88 (2006) Article DOI: 10.1021/jm060434q BindingDB Entry DOI: 10.7270/Q2J67F5X | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 170 total ) | Next | Last >> |