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Compile Data Set for Download or QSAR

Found 517 hits with Last Name = 'fink' and Initial = 'm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50326663
PNG
(CHEMBL1255022)
Show SMILES CCO[C@]12CCC(=O)[C@]3(C)Oc4c5c(C[C@H]1N(C)CC[C@@]235)ccc4O |r|
Show InChI InChI=1S/C20H25NO4/c1-4-24-20-8-7-15(23)18(2)19(20)9-10-21(3)14(20)11-12-5-6-13(22)17(25-18)16(12)19/h5-6,14,22H,4,7-11H2,1-3H3/t14-,18+,19+,20-/m1/s1
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0.100n/an/an/an/an/an/an/an/a



University of Innsbruck and Center for Molecular Biosciences Innsbruck-CMBI

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane


Bioorg Med Chem 18: 5071-80 (2010)


Article DOI: 10.1016/j.bmc.2010.05.071
BindingDB Entry DOI: 10.7270/Q2XP75XQ
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50326662
PNG
(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Show SMILES CO[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(C)CC[C@@]235)ccc4O |r|
Show InChI InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-11(20)15(14)23-16(17)12(21)5-6-18(17,22-2)13(19)9-10/h3-4,13,16,20H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1
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0.100n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548314
PNG
(CHEMBL4793888)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CCCCN)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.190n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548310
PNG
(CHEMBL4755067)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.360n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548285
PNG
(CHEMBL4792012)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.440n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50326661
PNG
(CHEMBL1254018 | CHEMBL1254291)
Show SMILES Oc1ccc(O)c2c1C[C@@H]1[C@@H]3CCC(=O)C[C@]23CCN1C=O |r|
Show InChI InChI=1S/C17H19NO4/c19-9-18-6-5-17-8-10(20)1-2-12(17)13(18)7-11-14(21)3-4-15(22)16(11)17/h3-4,9,12-13,21-22H,1-2,5-8H2/t12-,13+,17-/m0/s1
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0.460n/an/an/an/an/an/an/an/a



University of Innsbruck and Center for Molecular Biosciences Innsbruck-CMBI

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane


Bioorg Med Chem 18: 5071-80 (2010)


Article DOI: 10.1016/j.bmc.2010.05.071
BindingDB Entry DOI: 10.7270/Q2XP75XQ
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548313
PNG
(CHEMBL4741873)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](CCCCN)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.530n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548296
PNG
(CHEMBL4757240)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@H](Cc1ccccc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.610n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548309
PNG
(CHEMBL4788003)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.650n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548300
PNG
(CHEMBL4777389)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@H](C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.690n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548292
PNG
(CHEMBL4797321)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CC)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.760n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548322
PNG
(CHEMBL4782642)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.770n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548288
PNG
(CHEMBL4743953)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2NCCCC(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.770n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548286
PNG
(CHEMBL4789014)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.820n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548323
PNG
(CHEMBL4755734)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5(O)CC[C@H]2NCC(O)=O)ccc3O |r,THB:10:9:14:4.5.6|
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0.830n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548312
PNG
(CHEMBL4753934)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](Cc1ccc(O)cc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.830n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50336592
PNG
(2-{[(1S,5R,13R,14S,17S)-10-hydroxy-17-methoxy-4-me...)
Show SMILES CO[C@]12CC[C@H](NCC(O)=O)[C@@H]3Oc4c5c(C[C@H]1N(C)CC[C@@]235)ccc4O |r|
Show InChI InChI=1S/C20H26N2O5/c1-22-8-7-19-16-11-3-4-13(23)17(16)27-18(19)12(21-10-15(24)25)5-6-20(19,26-2)14(22)9-11/h3-4,12,14,18,21,23H,5-10H2,1-2H3,(H,24,25)/t12-,14+,18-,19-,20+/m0/s1
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0.890n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548320
PNG
(CHEMBL4754944)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](Cc1ccccc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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0.950n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548289
PNG
(CHEMBL4757463)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2NCCC(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548319
PNG
(CHEMBL4795312)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](Cc1ccccc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548310
PNG
(CHEMBL4755067)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548297
PNG
(CHEMBL4795517)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@H](C(C)C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50326659
PNG
(3,10-dimethoxy-17-methyl-(10S)-17-azatetracyclo[7....)
Show SMILES COc1cccc2C[C@H]3N(C)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 |r|
Show InChI InChI=1S/C19H25NO3/c1-20-10-9-18-12-14(21)7-8-19(18,23-3)16(20)11-13-5-4-6-15(22-2)17(13)18/h4-6,16H,7-12H2,1-3H3/t16-,18-,19-/m1/s1
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1.15n/an/an/an/an/an/an/an/a



University of Innsbruck and Center for Molecular Biosciences Innsbruck-CMBI

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane


Bioorg Med Chem 18: 5071-80 (2010)


Article DOI: 10.1016/j.bmc.2010.05.071
BindingDB Entry DOI: 10.7270/Q2XP75XQ
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548294
PNG
(CHEMBL4748047)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](C1CCCCC1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.20n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548295
PNG
(CHEMBL4783612)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@H](Cc1ccccc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548286
PNG
(CHEMBL4789014)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548308
PNG
(CHEMBL4761784)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CC(N)=O)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548309
PNG
(CHEMBL4788003)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548295
PNG
(CHEMBL4783612)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@H](Cc1ccccc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.30n/an/an/an/an/an/an/an/a


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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548307
PNG
(CHEMBL4760163)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](CC(N)=O)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548291
PNG
(CHEMBL4781006)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](CC)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548293
PNG
(CHEMBL4750229)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](C1CCCCC1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548314
PNG
(CHEMBL4793888)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CCCCN)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548290
PNG
(CHEMBL4776879)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2NCCC(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548287
PNG
(CHEMBL4740464)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2NCCCC(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.40n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548285
PNG
(CHEMBL4792012)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548304
PNG
(CHEMBL4740360)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CC(O)=O)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548299
PNG
(CHEMBL4780909)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@H](C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548302
PNG
(CHEMBL4761211)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CCC(O)=O)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548298
PNG
(CHEMBL4741203)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@H](C(C)C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548293
PNG
(CHEMBL4750229)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](C1CCCCC1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.70n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548297
PNG
(CHEMBL4795517)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@H](C(C)C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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TBA

Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548291
PNG
(CHEMBL4781006)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](CC)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.80n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548298
PNG
(CHEMBL4741203)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@H](C(C)C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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1.90n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548321
PNG
(CHEMBL4763643)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](C)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50326660
PNG
((-)-N-Allyl-4,14-dimethoxymorphinan-6-one | CHEMBL...)
Show SMILES COc1cccc2C[C@H]3N(CC=C)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 |r|
Show InChI InChI=1S/C21H27NO3/c1-4-11-22-12-10-20-14-16(23)8-9-21(20,25-3)18(22)13-15-6-5-7-17(24-2)19(15)20/h4-7,18H,1,8-14H2,2-3H3/t18-,20-,21-/m1/s1
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2n/an/an/an/an/an/an/an/a



University of Innsbruck and Center for Molecular Biosciences Innsbruck-CMBI

Curated by ChEMBL


Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane


Bioorg Med Chem 18: 5071-80 (2010)


Article DOI: 10.1016/j.bmc.2010.05.071
BindingDB Entry DOI: 10.7270/Q2XP75XQ
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548317
PNG
(CHEMBL4788604)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](CO)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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TBA

Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548318
PNG
(CHEMBL4741308)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](CO)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548312
PNG
(CHEMBL4753934)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@@H]2N[C@@H](Cc1ccc(O)cc1)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
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Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))
BDBM50548307
PNG
(CHEMBL4760163)
Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]5(CC[C@H]2N[C@@H](CC(N)=O)C(O)=O)OC)ccc3O |r,THB:10:9:14:4.5.6|
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
2.30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting me...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.8b01327
BindingDB Entry DOI: 10.7270/Q2RB7870
More data for this
Ligand-Target Pair
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