Compile Data Set for Download or QSAR

Found 583 hits with Last Name = 'florea' and Initial = 'bi'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM36514 (CID46912122 | MDW933, 5) Show SMILES CC1=CC(C)=[N+]2C1=C(CCCCc1cn(C[C@H]3[C@H]4O[C@H]4[C@H](O)[C@@H](O)[C@@H]3O)nn1)c1c(C)cc(C)n1[B-]2(F)F |c:4,7,t:1| Show InChI InChI=1S/C26H34BF2N5O4/c1-13-9-15(3)33-20(13)18(21-14(2)10-16(4)34(21)27(33,28)29)8-6-5-7-17-11-32(31-30-17)12-19-22(35)23(36)24(37)26-25(19)38-26/h9-11,19,22-26,35-37H,5-8,12H2,1-4H3/t19-,22-,23+,24-,25-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7	-48.4	1.24	n/a	n/a	n/a	n/a	5.2	37
Leiden University					Assay Description Enzymatic activity assay using fluorescent activity-based labeling method.				Nat Chem Biol 6: 907-13 (2010) Article DOI: 10.1038/nchembio.466 BindingDB Entry DOI: 10.7270/Q2FX77ST
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM36515 (CID46912120 | MDW941, 6) Show SMILES COc1ccc(cc1)C1=[N+]2C(C=C1)=C(CCCCc1cn(C[C@H]3[C@H]4O[C@H]4[C@H](O)[C@@H](O)[C@@H]3O)nn1)c1ccc(-c3ccc(OC)cc3)n1[B-]2(F)F |c:12,t:9,14| Show InChI InChI=1S/C36H38BF2N5O6/c1-48-24-11-7-21(8-12-24)28-15-17-30-26(31-18-16-29(44(31)37(38,39)43(28)30)22-9-13-25(49-2)14-10-22)6-4-3-5-23-19-42(41-40-23)20-27-32(45)33(46)34(47)36-35(27)50-36/h7-19,27,32-36,45-47H,3-6,20H2,1-2H3/t27-,32-,33+,34-,35-,36+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8	-48.1	1.94	n/a	n/a	n/a	n/a	5.2	37
Leiden University					Assay Description Enzymatic activity assay using fluorescent activity-based labeling method.				Nat Chem Biol 6: 907-13 (2010) Article DOI: 10.1038/nchembio.466 BindingDB Entry DOI: 10.7270/Q2FX77ST
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM36513 (CID46912128 | KY170, 4 | US9056847, Azido-cyclophe...) Show SMILES O[C@H]1[C@@H]2O[C@@H]2[C@H](CN=[N+]=[N-])[C@@H](O)[C@@H]1O Show InChI InChI=1S/C7H11N3O4/c8-10-9-1-2-3(11)4(12)5(13)7-6(2)14-7/h2-7,11-13H,1H2/t2-,3-,4+,5-,6-,7+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	44	-43.7	120	n/a	n/a	n/a	n/a	5.2	37
Leiden University					Assay Description Enzymatic activity assay using fluorescent activity-based labeling method.				Nat Chem Biol 6: 907-13 (2010) Article DOI: 10.1038/nchembio.466 BindingDB Entry DOI: 10.7270/Q2FX77ST
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM36512 (CID164227 | Cylcophellitol, 3 | US11826435, Compou...) Show SMILES OC[C@H]1[C@H]2O[C@H]2[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C7H12O5/c8-1-2-3(9)4(10)5(11)7-6(2)12-7/h2-11H,1H2/t2-,3-,4+,5-,6-,7+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	152	-40.5	150	n/a	n/a	n/a	n/a	5.2	37
Leiden University					Assay Description Enzymatic activity assay using fluorescent activity-based labeling method.				Nat Chem Biol 6: 907-13 (2010) Article DOI: 10.1038/nchembio.466 BindingDB Entry DOI: 10.7270/Q2FX77ST
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50078114 ((1S,2R,3S,4S,5R,6R)-7-Oxa-bicyclo[4.1.0]heptane-2,...) Show SMILES O[C@H]1[C@H]2O[C@H]2[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	5.30E+4	-25.4	9.49E+3	n/a	n/a	n/a	n/a	5.2	37
Leiden University					Assay Description Enzymatic activity assay using fluorescent activity-based labeling method.				Nat Chem Biol 6: 907-13 (2010) Article DOI: 10.1038/nchembio.466 BindingDB Entry DOI: 10.7270/Q2FX77ST
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 26S proteasome beta 5 using LLVY as substrate				J Med Chem 53: 2319-23 (2010) Article DOI: 10.1021/jm9015685 BindingDB Entry DOI: 10.7270/Q2WS8TCH
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536438 (CHEMBL4534488) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCC(C)CC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:4.3,19.20,31.41,wD:8.8,44.47,(77.52,-2.76,;77.84,-4.19,;79.29,-4.35,;76.76,-5.18,;77.08,-6.61,;75.74,-7.37,;74.42,-6.61,;74.42,-5.06,;73.08,-7.37,;73.08,-8.91,;74.42,-9.69,;74.41,-11.23,;75.73,-12,;77.07,-11.23,;77.07,-9.68,;75.73,-8.91,;71.75,-6.61,;70.41,-7.37,;70.41,-8.91,;69.07,-6.61,;69.07,-5.06,;70.41,-4.29,;71.75,-5.07,;73.09,-4.3,;73.09,-2.76,;74.42,-1.99,;71.74,-1.99,;70.41,-2.76,;67.74,-7.37,;66.4,-6.61,;66.4,-5.06,;65.07,-7.37,;63.74,-6.61,;62.4,-7.37,;61.08,-6.61,;59.75,-7.37,;59.73,-8.91,;61.08,-9.69,;62.4,-8.91,;65.07,-8.91,;66.35,-9.77,;67.64,-10.62,;78.42,-7.37,;78.42,-8.91,;79.75,-6.6,;80.84,-7.68,;79.74,-5.06,;81.08,-5.82,)| Show InChI InChI=1S/C37H50N6O5/c1-24(2)19-29(33(44)37(4)23-48-37)39-34(45)30(20-26-11-7-5-8-12-26)40-35(46)31(21-28-17-15-25(3)16-18-28)41-36(47)32(42-43-38)22-27-13-9-6-10-14-27/h5-14,24-25,28-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t25?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536438 (CHEMBL4534488) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCC(C)CC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:4.3,19.20,31.41,wD:8.8,44.47,(77.52,-2.76,;77.84,-4.19,;79.29,-4.35,;76.76,-5.18,;77.08,-6.61,;75.74,-7.37,;74.42,-6.61,;74.42,-5.06,;73.08,-7.37,;73.08,-8.91,;74.42,-9.69,;74.41,-11.23,;75.73,-12,;77.07,-11.23,;77.07,-9.68,;75.73,-8.91,;71.75,-6.61,;70.41,-7.37,;70.41,-8.91,;69.07,-6.61,;69.07,-5.06,;70.41,-4.29,;71.75,-5.07,;73.09,-4.3,;73.09,-2.76,;74.42,-1.99,;71.74,-1.99,;70.41,-2.76,;67.74,-7.37,;66.4,-6.61,;66.4,-5.06,;65.07,-7.37,;63.74,-6.61,;62.4,-7.37,;61.08,-6.61,;59.75,-7.37,;59.73,-8.91,;61.08,-9.69,;62.4,-8.91,;65.07,-8.91,;66.35,-9.77,;67.64,-10.62,;78.42,-7.37,;78.42,-8.91,;79.75,-6.6,;80.84,-7.68,;79.74,-5.06,;81.08,-5.82,)| Show InChI InChI=1S/C37H50N6O5/c1-24(2)19-29(33(44)37(4)23-48-37)39-34(45)30(20-26-11-7-5-8-12-26)40-35(46)31(21-28-17-15-25(3)16-18-28)41-36(47)32(42-43-38)22-27-13-9-6-10-14-27/h5-14,24-25,28-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t25?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307482 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H37F5N6O5/c1-19(2)14-23(32(48)36(3)18-52-36)43-34(50)25(17-22-27(37)29(39)31(41)30(40)28(22)38)45-33(49)24(15-20-10-6-4-7-11-20)44-35(51)26(46-47-42)16-21-12-8-5-9-13-21/h4-13,19,23-26H,14-18H2,1-3H3,(H,43,50)(H,44,51)(H,45,49)/t23-,24-,25-,26-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 26S proteasome beta 5 using LLVY as substrate				J Med Chem 53: 2319-23 (2010) Article DOI: 10.1021/jm9015685 BindingDB Entry DOI: 10.7270/Q2WS8TCH
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536425 (CHEMBL4563298) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C37H44N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536429 (CHEMBL4581491) Show SMILES COC1CCC(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)CC1 |r,wU:36.38,7.6,11.19,wD:25.26,43.45,(73.47,-11.43,;73.47,-12.97,;72.14,-13.74,;72.13,-15.28,;70.8,-16.05,;69.47,-15.27,;68.13,-16.05,;68.13,-17.59,;66.79,-18.35,;65.46,-17.59,;65.46,-16.05,;64.13,-18.35,;62.79,-17.59,;61.46,-18.35,;60.13,-17.59,;58.8,-18.35,;58.79,-19.9,;60.14,-20.67,;61.46,-19.89,;64.13,-19.89,;65.41,-20.75,;66.69,-21.6,;69.47,-18.35,;69.47,-19.89,;70.8,-17.59,;72.14,-18.35,;72.14,-19.89,;73.47,-20.67,;73.46,-22.21,;74.79,-22.98,;76.13,-22.21,;76.12,-20.66,;74.79,-19.9,;73.47,-17.59,;73.47,-16.05,;74.8,-18.35,;76.14,-17.59,;75.82,-16.16,;76.89,-15.17,;76.58,-13.75,;78.45,-15.33,;77.47,-18.35,;77.47,-19.89,;78.8,-17.58,;79.9,-18.66,;78.8,-16.04,;80.14,-16.8,;69.46,-13.74,;70.79,-12.97,)| Show InChI InChI=1S/C37H50N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-14,24,27-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t27?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536425 (CHEMBL4563298) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C37H44N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536429 (CHEMBL4581491) Show SMILES COC1CCC(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)CC1 |r,wU:36.38,7.6,11.19,wD:25.26,43.45,(73.47,-11.43,;73.47,-12.97,;72.14,-13.74,;72.13,-15.28,;70.8,-16.05,;69.47,-15.27,;68.13,-16.05,;68.13,-17.59,;66.79,-18.35,;65.46,-17.59,;65.46,-16.05,;64.13,-18.35,;62.79,-17.59,;61.46,-18.35,;60.13,-17.59,;58.8,-18.35,;58.79,-19.9,;60.14,-20.67,;61.46,-19.89,;64.13,-19.89,;65.41,-20.75,;66.69,-21.6,;69.47,-18.35,;69.47,-19.89,;70.8,-17.59,;72.14,-18.35,;72.14,-19.89,;73.47,-20.67,;73.46,-22.21,;74.79,-22.98,;76.13,-22.21,;76.12,-20.66,;74.79,-19.9,;73.47,-17.59,;73.47,-16.05,;74.8,-18.35,;76.14,-17.59,;75.82,-16.16,;76.89,-15.17,;76.58,-13.75,;78.45,-15.33,;77.47,-18.35,;77.47,-19.89,;78.8,-17.58,;79.9,-18.66,;78.8,-16.04,;80.14,-16.8,;69.46,-13.74,;70.79,-12.97,)| Show InChI InChI=1S/C37H50N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-14,24,27-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t27?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307480 (CHEMBL579296 | Pyrazine-2-carboxylic acid(1-[3-met...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)NC(=O)c1cnccn1)B1OC2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1 |r| Show InChI InChI=1S/C31H37BF6N4O4/c1-16(2)8-25(32-45-24-14-18-13-23(28(18,3)4)29(24,5)46-32)42-26(43)21(41-27(44)22-15-39-6-7-40-22)11-17-9-19(30(33,34)35)12-20(10-17)31(36,37)38/h6-7,9-10,12,15-16,18,21,23-25H,8,11,13-14H2,1-5H3,(H,41,44)(H,42,43)/t18-,21-,23-,24?,25-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 26S proteasome beta 5 using LLVY as substrate				J Med Chem 53: 2319-23 (2010) Article DOI: 10.1021/jm9015685 BindingDB Entry DOI: 10.7270/Q2WS8TCH
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536442 (CHEMBL4570216) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C[C@H]1CC[C@@H](CC1)c1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:16.32,1.0,33.44,18.18,wD:5.5,46.50,21.25,(48.13,-36.86,;48.13,-38.19,;46.79,-38.97,;45.46,-38.19,;45.46,-36.65,;44.12,-38.97,;44.12,-40.51,;45.46,-41.29,;45.45,-42.83,;46.78,-43.6,;48.12,-42.83,;48.12,-41.28,;46.78,-40.51,;42.79,-38.19,;41.45,-38.97,;41.45,-40.51,;40.11,-38.2,;40.11,-36.65,;41.44,-35.88,;41.43,-34.35,;42.77,-33.58,;44.1,-34.35,;44.09,-35.89,;42.76,-36.65,;45.42,-33.59,;46.75,-34.37,;48.08,-33.61,;48.09,-32.07,;46.75,-31.3,;45.43,-32.06,;38.78,-38.97,;37.44,-38.19,;37.44,-36.65,;36.11,-38.97,;34.77,-38.19,;33.43,-38.97,;32.1,-38.2,;30.77,-38.97,;30.76,-40.51,;32.11,-41.29,;33.43,-40.51,;36.11,-40.51,;37.39,-41.37,;38.67,-42.22,;49.47,-38.97,;49.47,-40.51,;50.8,-38.19,;51.89,-39.28,;50.79,-36.64,;52.13,-37.41,)| Show InChI InChI=1S/C39H46N6O5/c1-26(35(46)39(2)25-50-39)41-36(47)32(22-27-12-6-3-7-13-27)42-37(48)33(23-29-18-20-31(21-19-29)30-16-10-5-11-17-30)43-38(49)34(44-45-40)24-28-14-8-4-9-15-28/h3-17,26,29,31-34H,18-25H2,1-2H3,(H,41,47)(H,42,48)(H,43,49)/t26-,29-,31-,32-,33-,34-,39+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536439 (CHEMBL4581001) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C[C@H]1CC[C@@H](CC1)C1CCCCC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:16.32,1.0,33.44,18.18,wD:5.5,46.50,21.25,(72.07,-6.39,;72.07,-7.72,;70.74,-8.5,;69.41,-7.72,;69.41,-6.18,;68.07,-8.5,;68.07,-10.04,;69.41,-10.82,;69.4,-12.36,;70.73,-13.13,;72.07,-12.36,;72.06,-10.81,;70.73,-10.04,;66.73,-7.72,;65.4,-8.5,;65.4,-10.04,;64.06,-7.73,;64.06,-6.18,;65.39,-5.41,;65.38,-3.87,;66.72,-3.11,;68.04,-3.88,;68.04,-5.42,;66.71,-6.18,;69.37,-3.12,;70.7,-3.9,;72.03,-3.14,;72.04,-1.6,;70.7,-.83,;69.37,-1.59,;62.72,-8.5,;61.39,-7.72,;61.39,-6.18,;60.06,-8.5,;58.72,-7.72,;57.38,-8.5,;56.05,-7.73,;54.72,-8.5,;54.71,-10.04,;56.06,-10.82,;57.38,-10.04,;60.06,-10.04,;61.33,-10.9,;62.62,-11.75,;73.41,-8.5,;73.41,-10.04,;74.75,-7.71,;75.84,-8.81,;74.74,-6.17,;76.08,-6.94,)| Show InChI InChI=1S/C39H52N6O5/c1-26(35(46)39(2)25-50-39)41-36(47)32(22-27-12-6-3-7-13-27)42-37(48)33(23-29-18-20-31(21-19-29)30-16-10-5-11-17-30)43-38(49)34(44-45-40)24-28-14-8-4-9-15-28/h3-4,6-9,12-15,26,29-34H,5,10-11,16-25H2,1-2H3,(H,41,47)(H,42,48)(H,43,49)/t26-,29-,31-,32-,33-,34-,39+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517643 (CHEMBL4451682) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C30H41N7O5S/c1-20(2)16-26(35-30(40)27(36-37-32)18-22-8-6-5-7-9-22)29(39)33-21(3)28(38)34-25(14-15-43(4,41)42)17-23-10-12-24(19-31)13-11-23/h5-15,20-21,25-27H,16-19,31H2,1-4H3,(H,33,39)(H,34,38)(H,35,40)/b15-14+/t21-,25+,26-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517609 (CHEMBL4440581) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C30H41N7O6S/c1-20(2)15-25(34-29(40)26(36-37-32)17-21-7-5-4-6-8-21)28(39)35-27(19-38)30(41)33-24(13-14-44(3,42)43)16-22-9-11-23(18-31)12-10-22/h4-14,20,24-27,38H,15-19,31H2,1-3H3,(H,33,41)(H,34,40)(H,35,39)/b14-13+/t24-,25+,26+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517607 (CHEMBL4590398) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C31H43N7O6S/c1-20(2)16-26(35-30(41)27(37-38-33)18-22-8-6-5-7-9-22)29(40)36-28(21(3)39)31(42)34-25(14-15-45(4,43)44)17-23-10-12-24(19-32)13-11-23/h5-15,20-21,25-28,39H,16-19,32H2,1-4H3,(H,34,42)(H,35,41)(H,36,40)/b15-14+/t21-,25-,26+,27+,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536425 (CHEMBL4563298) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C37H44N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536425 (CHEMBL4563298) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C37H44N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517607 (CHEMBL4590398) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C31H43N7O6S/c1-20(2)16-26(35-30(41)27(37-38-33)18-22-8-6-5-7-9-22)29(40)36-28(21(3)39)31(42)34-25(14-15-45(4,43)44)17-23-10-12-24(19-32)13-11-23/h5-15,20-21,25-28,39H,16-19,32H2,1-4H3,(H,34,42)(H,35,41)(H,36,40)/b15-14+/t21-,25-,26+,27+,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517617 (CHEMBL4458756) Show SMILES COC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C31H43N7O6S/c1-21(2)16-26(35-30(40)27(37-38-33)18-22-8-6-5-7-9-22)29(39)36-28(20-44-3)31(41)34-25(14-15-45(4,42)43)17-23-10-12-24(19-32)13-11-23/h5-15,21,25-28H,16-20,32H2,1-4H3,(H,34,41)(H,35,40)(H,36,39)/b15-14+/t25-,26+,27+,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536451 (CHEMBL4528476) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C42H46N6O5/c1-28(2)23-34(38(49)42(3)27-53-42)44-39(50)35(24-29-13-7-4-8-14-29)45-40(51)36(25-31-19-21-33(22-20-31)32-17-11-6-12-18-32)46-41(52)37(47-48-43)26-30-15-9-5-10-16-30/h4-22,28,34-37H,23-27H2,1-3H3,(H,44,50)(H,45,51)(H,46,52)/t34-,35-,36-,37-,42+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536452 (CHEMBL4574722) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H44N6O5/c1-26(2)20-32(36(47)40(3)25-51-40)42-37(48)33(22-27-12-6-4-7-13-27)43-38(49)34(24-29-18-19-30-16-10-11-17-31(30)21-29)44-39(50)35(45-46-41)23-28-14-8-5-9-15-28/h4-19,21,26,32-35H,20,22-25H2,1-3H3,(H,42,48)(H,43,49)(H,44,50)/t32-,33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536453 (CHEMBL4587878) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C38H43N7O5/c1-24(2)18-30(34(46)38(3)23-50-38)41-35(47)31(19-25-12-6-4-7-13-25)42-36(48)32(21-27-22-40-29-17-11-10-16-28(27)29)43-37(49)33(44-45-39)20-26-14-8-5-9-15-26/h4-17,22,24,30-33,40H,18-21,23H2,1-3H3,(H,41,47)(H,42,48)(H,43,49)/t30-,31-,32-,33-,38+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536450 (CHEMBL4522697) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C38H48N4O7/c1-25(2)19-31(35(44)38(3)24-49-38)40-37(46)33(21-26-10-13-30(47-4)14-11-26)41-36(45)32(39-34(43)23-42-15-17-48-18-16-42)22-27-9-12-28-7-5-6-8-29(28)20-27/h5-14,20,25,31-33H,15-19,21-24H2,1-4H3,(H,39,43)(H,40,46)(H,41,45)/t31-,32-,33-,38+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536451 (CHEMBL4528476) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C42H46N6O5/c1-28(2)23-34(38(49)42(3)27-53-42)44-39(50)35(24-29-13-7-4-8-14-29)45-40(51)36(25-31-19-21-33(22-20-31)32-17-11-6-12-18-32)46-41(52)37(47-48-43)26-30-15-9-5-10-16-30/h4-22,28,34-37H,23-27H2,1-3H3,(H,44,50)(H,45,51)(H,46,52)/t34-,35-,36-,37-,42+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536453 (CHEMBL4587878) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C38H43N7O5/c1-24(2)18-30(34(46)38(3)23-50-38)41-35(47)31(19-25-12-6-4-7-13-25)42-36(48)32(21-27-22-40-29-17-11-10-16-28(27)29)43-37(49)33(44-45-39)20-26-14-8-5-9-15-26/h4-17,22,24,30-33,40H,18-21,23H2,1-3H3,(H,41,47)(H,42,48)(H,43,49)/t30-,31-,32-,33-,38+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536437 (CHEMBL4588350) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-24(2)19-29(33(44)37(4)23-48-37)39-34(45)30(20-26-11-7-5-8-12-26)40-35(46)31(21-28-17-15-25(3)16-18-28)41-36(47)32(42-43-38)22-27-13-9-6-10-14-27/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517643 (CHEMBL4451682) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C30H41N7O5S/c1-20(2)16-26(35-30(40)27(36-37-32)18-22-8-6-5-7-9-22)29(39)33-21(3)28(38)34-25(14-15-43(4,41)42)17-23-10-12-24(19-31)13-11-23/h5-15,20-21,25-27H,16-19,31H2,1-4H3,(H,33,39)(H,34,38)(H,35,40)/b15-14+/t21-,25+,26-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536457 (CHEMBL4555159) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])c1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C35H40N6O5/c1-23(2)19-27(31(42)35(3)22-46-35)37-32(43)28(20-24-13-7-4-8-14-24)38-34(45)30(26-17-11-6-12-18-26)39-33(44)29(40-41-36)21-25-15-9-5-10-16-25/h4-18,23,27-30H,19-22H2,1-3H3,(H,37,43)(H,38,45)(H,39,44)/t27-,28-,29-,30-,35+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536452 (CHEMBL4574722) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H44N6O5/c1-26(2)20-32(36(47)40(3)25-51-40)42-37(48)33(22-27-12-6-4-7-13-27)43-38(49)34(24-29-18-19-30-16-10-11-17-31(30)21-29)44-39(50)35(45-46-41)23-28-14-8-5-9-15-28/h4-19,21,26,32-35H,20,22-25H2,1-3H3,(H,42,48)(H,43,49)(H,44,50)/t32-,33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536440 (CHEMBL4560006) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCCC2CCCCC12)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H54N6O5/c1-26(2)21-32(36(47)40(3)25-51-40)42-37(48)33(22-27-13-6-4-7-14-27)43-38(49)34(24-30-19-12-18-29-17-10-11-20-31(29)30)44-39(50)35(45-46-41)23-28-15-8-5-9-16-28/h4-9,13-16,26,29-35H,10-12,17-25H2,1-3H3,(H,42,48)(H,43,49)(H,44,50)/t29?,30?,31?,32-,33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536458 (CHEMBL4556673) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H44N6O5/c1-26(2)21-32(36(47)40(3)25-51-40)42-37(48)33(22-27-13-6-4-7-14-27)43-38(49)34(24-30-19-12-18-29-17-10-11-20-31(29)30)44-39(50)35(45-46-41)23-28-15-8-5-9-16-28/h4-20,26,32-35H,21-25H2,1-3H3,(H,42,48)(H,43,49)(H,44,50)/t32-,33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536436 (CHEMBL4556581) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C40H50N4O7/c1-27(2)22-33(37(46)40(3)26-51-40)42-39(48)35(24-29-12-16-32(49-4)17-13-29)43-38(47)34(41-36(45)25-44-18-20-50-21-19-44)23-28-10-14-31(15-11-28)30-8-6-5-7-9-30/h5-17,27,33-35H,18-26H2,1-4H3,(H,41,45)(H,42,48)(H,43,47)/t33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536458 (CHEMBL4556673) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H44N6O5/c1-26(2)21-32(36(47)40(3)25-51-40)42-37(48)33(22-27-13-6-4-7-14-27)43-38(49)34(24-30-19-12-18-29-17-10-11-20-31(29)30)44-39(50)35(45-46-41)23-28-15-8-5-9-16-28/h4-20,26,32-35H,21-25H2,1-3H3,(H,42,48)(H,43,49)(H,44,50)/t32-,33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536457 (CHEMBL4555159) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])c1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C35H40N6O5/c1-23(2)19-27(31(42)35(3)22-46-35)37-32(43)28(20-24-13-7-4-8-14-24)38-34(45)30(26-17-11-6-12-18-26)39-33(44)29(40-41-36)21-25-15-9-5-10-16-25/h4-18,23,27-30H,19-22H2,1-3H3,(H,37,43)(H,38,45)(H,39,44)/t27-,28-,29-,30-,35+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536428 (CHEMBL4556631) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2cccc3ccccc23)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C38H48N4O7/c1-25(2)20-31(35(44)38(3)24-49-38)40-36(45)32(21-26-12-14-29(47-4)15-13-26)41-37(46)33(39-34(43)23-42-16-18-48-19-17-42)22-28-10-7-9-27-8-5-6-11-30(27)28/h5-15,25,31-33H,16-24H2,1-4H3,(H,39,43)(H,40,45)(H,41,46)/t31-,32-,33-,38+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536430 (CHEMBL4543267) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CC2CCC1C2)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,THB:20:21:27:24.25| Show InChI InChI=1S/C37H48N6O5/c1-23(2)16-29(33(44)37(3)22-48-37)39-34(45)30(19-24-10-6-4-7-11-24)40-35(46)31(21-28-18-26-14-15-27(28)17-26)41-36(47)32(42-43-38)20-25-12-8-5-9-13-25/h4-13,23,26-32H,14-22H2,1-3H3,(H,39,45)(H,40,46)(H,41,47)/t26?,27?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536436 (CHEMBL4556581) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)CN2CCOCC2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C40H50N4O7/c1-27(2)22-33(37(46)40(3)26-51-40)42-39(48)35(24-29-12-16-32(49-4)17-13-29)43-38(47)34(41-36(45)25-44-18-20-50-21-19-44)23-28-10-14-31(15-11-28)30-8-6-5-7-9-30/h5-17,27,33-35H,18-26H2,1-4H3,(H,41,45)(H,42,48)(H,43,47)/t33-,34-,35-,40+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536437 (CHEMBL4588350) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-24(2)19-29(33(44)37(4)23-48-37)39-34(45)30(20-26-11-7-5-8-12-26)40-35(46)31(21-28-17-15-25(3)16-18-28)41-36(47)32(42-43-38)22-27-13-9-6-10-14-27/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair

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