Compile Data Set for Download or QSAR

Found 95 hits with Last Name = 'foster' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50405683 (CHEMBL174909) Show SMILES CCCCN1C(=O)C2CC2(C1=O)c1ccc(N)cc1 Show InChI InChI=1S/C15H18N2O2/c1-2-3-8-17-13(18)12-9-15(12,14(17)19)10-4-6-11(16)7-5-10/h4-7,12H,2-3,8-9,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Apparent inhibition constant (Ki) for cytochrome P450 19A1 with androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50011767 (1-(4-Amino-phenyl)-3-pentyl-3-aza-bicyclo[3.1.0]he...) Show SMILES CCCCCN1C(=O)C2CC2(C1=O)c1ccc(N)cc1 Show InChI InChI=1S/C16H20N2O2/c1-2-3-4-9-18-14(19)13-10-16(13,15(18)20)11-5-7-12(17)8-6-11/h5-8,13H,2-4,9-10,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50405688 (CHEMBL174407) Show SMILES CCCN1C(=O)C2CC2(C1=O)c1ccc(N)cc1 Show InChI InChI=1S/C14H16N2O2/c1-2-7-16-12(17)11-8-14(11,13(16)18)9-3-5-10(15)6-4-9/h3-6,11H,2,7-8,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50250422 ((+)-N-methyl-laurotetanine | CHEMBL464099 | N-meth...) Show SMILES COc1cc-2c(C[C@@H]3N(C)CCc4cc(OC)c(OC)c-2c34)cc1O |r| Show InChI InChI=1S/C20H23NO4/c1-21-6-5-11-9-17(24-3)20(25-4)19-13-10-16(23-2)15(22)8-12(13)7-14(21)18(11)19/h8-10,14,22H,5-7H2,1-4H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tom's of Maine Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cells				J Nat Prod 69: 432-5 (2006) Article DOI: 10.1021/np058114h BindingDB Entry DOI: 10.7270/Q2V98907
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024544 (3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCCCCCCCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-11-18(15-9-13-19-14-10-15)12-8-16(21)20-17(18)22/h9-10,13-14H,2-8,11-12H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with androstenedione				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50015983 ((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...) Show SMILES CCCCCCCCN1C(=O)CCC(CC)(C1=O)c1ccncc1 Show InChI InChI=1S/C20H30N2O2/c1-3-5-6-7-8-9-16-22-18(23)10-13-20(4-2,19(22)24)17-11-14-21-15-12-17/h11-12,14-15H,3-10,13,16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with testosterone				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024544 (3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCCCCCCCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-11-18(15-9-13-19-14-10-15)12-8-16(21)20-17(18)22/h9-10,13-14H,2-8,11-12H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with androstenedione				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50015983 ((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...) Show SMILES CCCCCCCCN1C(=O)CCC(CC)(C1=O)c1ccncc1 Show InChI InChI=1S/C20H30N2O2/c1-3-5-6-7-8-9-16-22-18(23)10-13-20(4-2,19(22)24)17-11-14-21-15-12-17/h11-12,14-15H,3-10,13,16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with androstenedione				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM8885 ((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...) Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |r,t:18| Show InChI InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental aromatase Cytochrome P450 19A1				J Med Chem 26: 50-4 (1983) BindingDB Entry DOI: 10.7270/Q2V125CG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human placental cytochrome P450 19A1				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory constant (Ki) for Cytochrome P450 19A1				J Med Chem 28: 200-4 (1985) BindingDB Entry DOI: 10.7270/Q2WM1FK8
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50015985 (3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C12H14N2O2/c1-2-12(9-4-7-13-8-5-9)6-3-10(15)14-11(12)16/h4-5,7-8H,2-3,6H2,1H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory constant (Ki) for Cytochrome P450 19A1				J Med Chem 28: 200-4 (1985) BindingDB Entry DOI: 10.7270/Q2WM1FK8
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50015985 (3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C12H14N2O2/c1-2-12(9-4-7-13-8-5-9)6-3-10(15)14-11(12)16/h4-5,7-8H,2-3,6H2,1H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with androstenedione				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50011760 (1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.0]hexane-2,4-...) Show SMILES Nc1ccc(cc1)C12CC1C(=O)NC2=O Show InChI InChI=1S/C11H10N2O2/c12-7-3-1-6(2-4-7)11-5-8(11)9(14)13-10(11)15/h1-4,8H,5,12H2,(H,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 androstenedione				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with testosterone				J Med Chem 31: 971-6 (1988) BindingDB Entry DOI: 10.7270/Q2154J7X
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with androstenedione				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50259677 (CHEMBL481839 | escholtzine) Show SMILES CN1[C@H]2Cc3cc4OCOc4cc3[C@@H]1Cc1cc3OCOc3cc21 |r,TLB:0:1:14.15.23:3.12.4| Show InChI InChI=1S/C19H17NO4/c1-20-14-2-10-4-16-18(23-8-21-16)6-12(10)15(20)3-11-5-17-19(7-13(11)14)24-9-22-17/h4-7,14-15H,2-3,8-9H2,1H3/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tom's of Maine Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cells				J Nat Prod 69: 432-5 (2006) Article DOI: 10.1021/np058114h BindingDB Entry DOI: 10.7270/Q2V98907
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50015985 (3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C12H14N2O2/c1-2-12(9-4-7-13-8-5-9)6-3-10(15)14-11(12)16/h4-5,7-8H,2-3,6H2,1H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with androstenedione				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24922 (5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[...) Show SMILES NC(=O)Nc1snc(SC2CCCCc3ccccc23)c1C(N)=O Show InChI InChI=1S/C16H18N4O2S2/c17-13(21)12-14(19-16(18)22)24-20-15(12)23-11-8-4-2-6-9-5-1-3-7-10(9)11/h1,3,5,7,11H,2,4,6,8H2,(H2,17,21)(H3,18,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24923 (5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-b...) Show SMILES NC(=O)Nc1snc(S[C@@H]2CCCCc3ccccc23)c1C(N)=O |r| Show InChI InChI=1S/C16H18N4O2S2/c17-13(21)12-14(19-16(18)22)24-20-15(12)23-11-8-4-2-6-9-5-1-3-7-10(9)11/h1,3,5,7,11H,2,4,6,8H2,(H2,17,21)(H3,18,19,22)/t11-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24899 (3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylca...) Show SMILES CNC(=O)Nc1snc(SC(C)c2ccc(Cl)cc2)c1C(N)=O Show InChI InChI=1S/C14H15ClN4O2S2/c1-7(8-3-5-9(15)6-4-8)22-13-10(11(16)20)12(23-19-13)18-14(21)17-2/h3-7H,1-2H3,(H2,16,20)(H2,17,18,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24901 (3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...) Show SMILES CC[C@@H](Sc1nsc(NC(=O)NC)c1C(N)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H17ClN4O2S2/c1-3-10(8-4-6-9(16)7-5-8)23-14-11(12(17)21)13(24-20-14)19-15(22)18-2/h4-7,10H,3H2,1-2H3,(H2,17,21)(H2,18,19,22)/t10-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24898 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(methylcar...) Show SMILES CNC(=O)Nc1snc(SCc2ccc(Cl)cc2)c1C(N)=O Show InChI InChI=1S/C13H13ClN4O2S2/c1-16-13(20)17-11-9(10(15)19)12(18-22-11)21-6-7-2-4-8(14)5-3-7/h2-5H,6H2,1H3,(H2,15,19)(H2,16,17,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24919 (3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5...) Show SMILES CNC(=O)Nc1snc(SC2CCc3cc(Cl)ccc23)c1C(N)=O Show InChI InChI=1S/C15H15ClN4O2S2/c1-18-15(22)19-13-11(12(17)21)14(20-24-13)23-10-5-2-7-6-8(16)3-4-9(7)10/h3-4,6,10H,2,5H2,1H3,(H2,17,21)(H2,18,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24900 (3-{[1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylc...) Show SMILES CCC(Sc1nsc(NC(=O)NC)c1C(N)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H17ClN4O2S2/c1-3-10(8-4-6-9(16)7-5-8)23-14-11(12(17)21)13(24-20-14)19-15(22)18-2/h4-7,10H,3H2,1-2H3,(H2,17,21)(H2,18,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24918 (5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-ind...) Show SMILES NC(=O)Nc1snc(SC2CCc3cc(Cl)ccc23)c1C(N)=O Show InChI InChI=1S/C14H13ClN4O2S2/c15-7-2-3-8-6(5-7)1-4-9(8)22-13-10(11(16)20)12(23-19-13)18-14(17)21/h2-3,5,9H,1,4H2,(H2,16,20)(H3,17,18,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24903 (3-{[1-(4-chlorophenyl)-2-methylpropyl]sulfanyl}-5-...) Show SMILES CNC(=O)Nc1snc(SC(C(C)C)c2ccc(Cl)cc2)c1C(N)=O Show InChI InChI=1S/C16H19ClN4O2S2/c1-8(2)12(9-4-6-10(17)7-5-9)24-15-11(13(18)22)14(25-21-15)20-16(23)19-3/h4-8,12H,1-3H3,(H2,18,22)(H2,19,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24910 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-3-...) Show SMILES NC(=O)c1c(SCc2ccc(Cl)cc2)nsc1Nc1cccnc1 Show InChI InChI=1S/C16H13ClN4OS2/c17-11-5-3-10(4-6-11)9-23-16-13(14(18)22)15(24-21-16)20-12-2-1-7-19-8-12/h1-8,20H,9H2,(H2,18,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24914 (3-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...) Show SMILES NC(=O)c1c(SCc2ccccc2Cl)nsc1Nc1ccncc1 Show InChI InChI=1S/C16H13ClN4OS2/c17-12-4-2-1-3-10(12)9-23-16-13(14(18)22)15(24-21-16)20-11-5-7-19-8-6-11/h1-8H,9H2,(H2,18,22)(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24911 (3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-(pyridin-3...) Show SMILES CC(Sc1nsc(Nc2cccnc2)c1C(N)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H15ClN4OS2/c1-10(11-4-6-12(18)7-5-11)24-17-14(15(19)23)16(25-22-17)21-13-3-2-8-20-9-13/h2-10,21H,1H3,(H2,19,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24909 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-2-...) Show SMILES NC(=O)c1c(SCc2ccc(Cl)cc2)nsc1Nc1ccccn1 Show InChI InChI=1S/C16H13ClN4OS2/c17-11-6-4-10(5-7-11)9-23-16-13(14(18)22)15(24-21-16)20-12-3-1-2-8-19-12/h1-8H,9H2,(H2,18,22)(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24904 (3-{[1-(4-chlorophenyl)butyl]sulfanyl}-5-[(methylca...) Show SMILES CCCC(Sc1nsc(NC(=O)NC)c1C(N)=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H19ClN4O2S2/c1-3-4-11(9-5-7-10(17)8-6-9)24-15-12(13(18)22)14(25-21-15)20-16(23)19-2/h5-8,11H,3-4H2,1-2H3,(H2,18,22)(H2,19,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24913 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...) Show SMILES NC(=O)c1c(SCc2ccc(Cl)cc2)nsc1Nc1ccncc1 Show InChI InChI=1S/C16H13ClN4OS2/c17-11-3-1-10(2-4-11)9-23-16-13(14(18)22)15(24-21-16)20-12-5-7-19-8-6-12/h1-8H,9H2,(H2,18,22)(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24915 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-...) Show SMILES NC(=O)c1c(SCc2ccc(Cl)cc2)nsc1Nc1ccncn1 Show InChI InChI=1S/C15H12ClN5OS2/c16-10-3-1-9(2-4-10)7-23-15-12(13(17)22)14(24-21-15)20-11-5-6-18-8-19-11/h1-6,8H,7H2,(H2,17,22)(H,18,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24902 (3-{[(1S)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...) Show SMILES CC[C@H](Sc1nsc(NC(=O)NC)c1C(N)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H17ClN4O2S2/c1-3-10(8-4-6-9(16)7-5-8)23-14-11(12(17)21)13(24-20-14)19-15(22)18-2/h4-7,10H,3H2,1-2H3,(H2,17,21)(H2,18,19,22)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24917 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-oxo-1,6...) Show SMILES NC(=O)c1c(SCc2ccc(Cl)cc2)nsc1Nc1ccc(=O)[nH]c1 Show InChI InChI=1S/C16H13ClN4O2S2/c17-10-3-1-9(2-4-10)8-24-16-13(14(18)23)15(25-21-16)20-11-5-6-12(22)19-7-11/h1-7,20H,8H2,(H2,18,23)(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24924 (5-(carbamoylamino)-3-[(5S)-6,7,8,9-tetrahydro-5H-b...) Show SMILES NC(=O)Nc1snc(S[C@H]2CCCCc3ccccc23)c1C(N)=O |r| Show InChI InChI=1S/C16H18N4O2S2/c17-13(21)12-14(19-16(18)22)24-20-15(12)23-11-8-4-2-6-9-5-1-3-7-10(9)11/h1,3,5,7,11H,2,4,6,8H2,(H2,17,21)(H3,18,19,22)/t11-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24920 (5-(carbamoylamino)-3-(1,2,3,4-tetrahydronaphthalen...) Show SMILES NC(=O)Nc1snc(SC2CCCc3ccccc23)c1C(N)=O Show InChI InChI=1S/C15H16N4O2S2/c16-12(20)11-13(18-15(17)21)23-19-14(11)22-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7H2,(H2,16,20)(H3,17,18,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24905 (3-{[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]sulfan...) Show SMILES CNC(=O)Nc1snc(SC(c2ccc(Cl)cc2)C(F)(F)F)c1C(N)=O Show InChI InChI=1S/C14H12ClF3N4O2S2/c1-20-13(24)21-11-8(10(19)23)12(22-26-11)25-9(14(16,17)18)6-2-4-7(15)5-3-6/h2-5,9H,1H3,(H2,19,23)(H2,20,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24921 (5-[(methylcarbamoyl)amino]-3-(1,2,3,4-tetrahydrona...) Show SMILES CNC(=O)Nc1snc(SC2CCCc3ccccc23)c1C(N)=O Show InChI InChI=1S/C16H18N4O2S2/c1-18-16(22)19-14-12(13(17)21)15(20-24-14)23-11-8-4-6-9-5-2-3-7-10(9)11/h2-3,5,7,11H,4,6,8H2,1H3,(H2,17,21)(H2,18,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24916 (3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-methoxy...) Show SMILES COc1ccc(Nc2snc(SCc3ccc(Cl)cc3)c2C(N)=O)cn1 Show InChI InChI=1S/C17H15ClN4O2S2/c1-24-13-7-6-12(8-20-13)21-16-14(15(19)23)17(22-26-16)25-9-10-2-4-11(18)5-3-10/h2-8,21H,9H2,1H3,(H2,19,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024544 (3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCCCCCCCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-11-18(15-9-13-19-14-10-15)12-8-16(21)20-17(18)22/h9-10,13-14H,2-8,11-12H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human placental cytochrome P450 19A1				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024544 (3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCCCCCCCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-11-18(15-9-13-19-14-10-15)12-8-16(21)20-17(18)22/h9-10,13-14H,2-8,11-12H2,1H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with testosterone				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24912 (3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamin...) Show SMILES NC(=O)c1c(SCC2CCCCC2)nsc1Nc1cccnc1 Show InChI InChI=1S/C16H20N4OS2/c17-14(21)13-15(19-12-7-4-8-18-9-12)23-20-16(13)22-10-11-5-2-1-3-6-11/h4,7-9,11,19H,1-3,5-6,10H2,(H2,17,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50015983 ((S)-3-Ethyl-1-octyl-4,5-dihydro-3H-[3,4']bipyridin...) Show SMILES CCCCCCCCN1C(=O)CCC(CC)(C1=O)c1ccncc1 Show InChI InChI=1S/C20H30N2O2/c1-3-5-6-7-8-9-16-22-18(23)10-13-20(4-2,19(22)24)17-11-14-21-15-12-17/h11-12,14-15H,3-10,13,16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human placental cytochrome P450 19A1 with testosterone				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024550 (3-Ethyl-1-heptyl-4,5-dihydro-3H-[3,4']bipyridinyl-...) Show SMILES CCCCCCCN1C(=O)CCC(CC)(C1=O)c1ccncc1 Show InChI InChI=1S/C19H28N2O2/c1-3-5-6-7-8-15-21-17(22)9-12-19(4-2,18(21)23)16-10-13-20-14-11-16/h10-11,13-14H,3-9,12,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human placental cytochrome P450 19A1				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024555 (3-Nonyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCCCCCCCCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C19H28N2O2/c1-2-3-4-5-6-7-8-12-19(16-10-14-20-15-11-16)13-9-17(22)21-18(19)23/h10-11,14-15H,2-9,12-13H2,1H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human placental cytochrome P450 19A1				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024557 (3-Pentyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dion...) Show SMILES CCCCCC1(CCC(=O)NC1=O)c1ccncc1 Show InChI InChI=1S/C15H20N2O2/c1-2-3-4-8-15(12-6-10-16-11-7-12)9-5-13(18)17-14(15)19/h6-7,10-11H,2-5,8-9H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human placental cytochrome P450 19A1				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM24906 (3-{[(4-chlorophenyl)(phenyl)methyl]sulfanyl}-5-[(m...) Show SMILES CNC(=O)Nc1snc(SC(c2ccccc2)c2ccc(Cl)cc2)c1C(N)=O Show InChI InChI=1S/C19H17ClN4O2S2/c1-22-19(26)23-17-14(16(21)25)18(24-28-17)27-15(11-5-3-2-4-6-11)12-7-9-13(20)10-8-12/h2-10,15H,1H3,(H2,21,25)(H2,22,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	7.4	22
Pfizer					Assay Description The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...				Bioorg Med Chem Lett 16: 3444-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.003 BindingDB Entry DOI: 10.7270/Q26Q1VH5
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50024553 (3-Ethyl-1-nonyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...) Show SMILES CCCCCCCCCN1C(=O)CCC(CC)(C1=O)c1ccncc1 Show InChI InChI=1S/C21H32N2O2/c1-3-5-6-7-8-9-10-17-23-19(24)11-14-21(4-2,20(23)25)18-12-15-22-16-13-18/h12-13,15-16H,3-11,14,17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human placental cytochrome P450 19A1				J Med Chem 30: 1550-4 (1987) BindingDB Entry DOI: 10.7270/Q2GM869Q
					More data for this Ligand-Target Pair

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