Compile Data Set for Download or QSAR

Found 77 hits with Last Name = 'frauli' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332633 (CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...) Show SMILES Cc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O3/c1-11-6-8-12(9-7-11)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)23-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332634 (CHEMBL1630807 | N-(4-Methoxyphenyl)-7-oxo-7,7a-dih...) Show SMILES COc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O4/c1-23-12-8-6-11(7-9-12)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)24-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332632 (CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...) Show SMILES Clc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C17H13ClN2O3/c18-10-5-7-11(8-6-10)19-16(21)17-9-13(17)15(20-22)12-3-1-2-4-14(12)23-17/h1-8,13,15H,9H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332631 (CHEMBL1630804 | N-(4-Fluorophenyl)-7-oxo-7,7a-dihy...) Show SMILES Fc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C17H13FN2O3/c18-10-5-7-11(8-6-10)19-16(21)17-9-13(17)15(20-22)12-3-1-2-4-14(12)23-17/h1-8,13,15H,9H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332632 (CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...) Show SMILES Clc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C17H13ClN2O3/c18-10-5-7-11(8-6-10)19-16(21)17-9-13(17)15(20-22)12-3-1-2-4-14(12)23-17/h1-8,13,15H,9H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332634 (CHEMBL1630807 | N-(4-Methoxyphenyl)-7-oxo-7,7a-dih...) Show SMILES COc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O4/c1-23-12-8-6-11(7-9-12)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)24-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332633 (CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...) Show SMILES Cc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O3/c1-11-6-8-12(9-7-11)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)23-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50060137 ((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...) Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50191052 ((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...) Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.78E+5	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR6 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50060137 ((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...) Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50060137 ((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...) Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+6	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR7 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50191052 ((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...) Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR8 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50060137 ((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...) Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR5 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50060137 ((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...) Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR8 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50060137 ((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...) Show SMILES N[C@]1(C[C@@H]([C@@H](C1)C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C8H11NO6/c9-8(7(14)15)1-3(5(10)11)4(2-8)6(12)13/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR6 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50191052 ((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...) Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	4.83E+4	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50191052 ((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...) Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR5 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50191052 ((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...) Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50191052 ((2S,4S)-4-amino-1-((E)-3-carboxyacryloyl)pyrrolidi...) Show SMILES N[C@]1(C[C@H](N(C1)C(=O)\C=C\C(O)=O)C(O)=O)C(O)=O Show InChI InChI=1S/C10H12N2O7/c11-10(9(18)19)3-5(8(16)17)12(4-10)6(13)1-2-7(14)15/h1-2,5H,3-4,11H2,(H,14,15)(H,16,17)(H,18,19)/b2-1+/t5-,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+6	n/a	n/a	n/a	n/a
Faust Pharmaceuticals Curated by ChEMBL					Assay Description Activity at rat mGluR1 receptor measured as intracellular calcium concentration in HEK293 cells				Bioorg Med Chem Lett 16: 4856-60 (2006) Article DOI: 10.1016/j.bmcl.2006.06.062 BindingDB Entry DOI: 10.7270/Q2833RNW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50332632 (CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...) Show SMILES Clc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C17H13ClN2O3/c18-10-5-7-11(8-6-10)19-16(21)17-9-13(17)15(20-22)12-3-1-2-4-14(12)23-17/h1-8,13,15H,9H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50332633 (CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...) Show SMILES Cc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O3/c1-11-6-8-12(9-7-11)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)23-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50332634 (CHEMBL1630807 | N-(4-Methoxyphenyl)-7-oxo-7,7a-dih...) Show SMILES COc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O4/c1-23-12-8-6-11(7-9-12)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)24-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50116514 (CHEMBL507522) Show SMILES [H][C@@]12C[C@@]1(Oc1ccccc1\C2=N\O)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15-/t13-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Inhibitory activity against human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50116514 (CHEMBL507522) Show SMILES [H][C@@]12C[C@@]1(Oc1ccccc1\C2=N\O)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15-/t13-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241541 (CHEMBL4087749) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2ccccc2o1 Show InChI InChI=1S/C17H11NO3/c19-18-13-10-17(21-15-8-4-2-6-12(13)15)16-9-11-5-1-3-7-14(11)20-16/h1-10,19H/b18-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241542 (CHEMBL4065348) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C17H12N2O2/c20-19-14-10-17(21-16-8-4-2-6-12(14)16)15-9-11-5-1-3-7-13(11)18-15/h1-10,18,20H/b19-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241543 (CHEMBL4060429) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cnc2ccccc2c1 Show InChI InChI=1S/C18H12N2O2/c21-20-16-10-18(22-17-8-4-2-6-14(16)17)13-9-12-5-1-3-7-15(12)19-11-13/h1-11,21H/b20-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241544 (CHEMBL4081595) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2ccccc2cn1 Show InChI InChI=1S/C18H12N2O2/c21-20-15-10-18(22-17-8-4-3-7-14(15)17)16-9-12-5-1-2-6-13(12)11-19-16/h1-11,21H/b20-15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241545 (CHEMBL4059644) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2cnccc2cn1 Show InChI InChI=1S/C17H11N3O2/c21-20-14-8-17(22-16-4-2-1-3-13(14)16)15-7-12-9-18-6-5-11(12)10-19-15/h1-10,21H/b20-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241546 (CHEMBL4071024) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2ncccc2cn1 Show InChI InChI=1S/C17H11N3O2/c21-20-14-9-17(22-16-6-2-1-5-12(14)16)15-8-13-11(10-19-15)4-3-7-18-13/h1-10,21H/b20-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241547 (CHEMBL4097178) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2ccsc2cn1 Show InChI InChI=1S/C16H10N2O2S/c19-18-12-8-15(20-14-4-2-1-3-11(12)14)13-7-10-5-6-21-16(10)9-17-13/h1-9,19H/b18-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241548 (CHEMBL4089473) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cn2cccc2cn1 Show InChI InChI=1S/C16H11N3O2/c20-18-13-8-16(21-15-6-2-1-5-12(13)15)14-10-19-7-3-4-11(19)9-17-14/h1-10,20H/b18-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241549 (CHEMBL4068295) Show SMILES Cn1ccc2cc(ncc12)-c1c\c(=N/O)c2ccccc2o1 Show InChI InChI=1S/C17H13N3O2/c1-20-7-6-11-8-14(18-10-15(11)20)17-9-13(19-21)12-4-2-3-5-16(12)22-17/h2-10,21H,1H3/b19-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241550 (CHEMBL4067271) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2cc[nH]c2cn1 Show InChI InChI=1S/C16H11N3O2/c20-19-12-8-16(21-15-4-2-1-3-11(12)15)13-7-10-5-6-17-14(10)9-18-13/h1-9,17,20H/b19-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241551 (CHEMBL4088412) Show SMILES O\N=c1/cc(oc2ccc(cc12)C(F)(F)F)-c1cc2ccccc2cn1 Show InChI InChI=1S/C19H11F3N2O2/c20-19(21,22)13-5-6-17-14(8-13)15(24-25)9-18(26-17)16-7-11-3-1-2-4-12(11)10-23-16/h1-10,25H/b24-15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241552 (CHEMBL4085101) Show SMILES O\N=c1/cc(oc2ccc(OCCN3CCC(F)(F)CC3)cc12)-c1cc2sccc2cn1 Show InChI InChI=1S/C23H21F2N3O3S/c24-23(25)4-6-28(7-5-23)8-9-30-16-1-2-20-17(11-16)18(27-29)12-21(31-20)19-13-22-15(14-26-19)3-10-32-22/h1-3,10-14,29H,4-9H2/b27-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241554 (CHEMBL4063474) Show SMILES O\N=c1/cc(oc2ccc(OCCN3CCOCC3)cc12)-c1cc2sccc2cn1 Show InChI InChI=1S/C22H21N3O4S/c26-24-18-12-21(19-13-22-15(14-23-19)3-10-30-22)29-20-2-1-16(11-17(18)20)28-9-6-25-4-7-27-8-5-25/h1-3,10-14,26H,4-9H2/b24-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241555 (CHEMBL4062968) Show SMILES COCCOc1ccc2oc(c\c(=N/O)c2c1)-c1cc2cccn2cn1 Show InChI InChI=1S/C19H17N3O4/c1-24-7-8-25-14-4-5-18-15(10-14)16(21-23)11-19(26-18)17-9-13-3-2-6-22(13)12-20-17/h2-6,9-12,23H,7-8H2,1H3/b21-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241556 (CHEMBL4083118) Show SMILES O\N=c1/cc(oc2cc(CCc3ccccc3)ccc12)-c1cc2ccccc2cn1 Show InChI InChI=1S/C26H20N2O2/c29-28-23-16-26(24-15-20-8-4-5-9-21(20)17-27-24)30-25-14-19(12-13-22(23)25)11-10-18-6-2-1-3-7-18/h1-9,12-17,29H,10-11H2/b28-23+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241557 (CHEMBL4101095) Show SMILES COCCOc1ccc2c(c1)oc(c\c2=N/O)-c1cc2ccccc2cn1 Show InChI InChI=1S/C21H18N2O4/c1-25-8-9-26-16-6-7-17-18(23-24)12-21(27-20(17)11-16)19-10-14-4-2-3-5-15(14)13-22-19/h2-7,10-13,24H,8-9H2,1H3/b23-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.01E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241559 (CHEMBL4093353) Show SMILES CN1CCN(CCOc2ccc3oc(c\c(=N/O)c3c2)-c2cc3ccccc3cn2)CC1 Show InChI InChI=1S/C25H26N4O3/c1-28-8-10-29(11-9-28)12-13-31-20-6-7-24-21(15-20)22(27-30)16-25(32-24)23-14-18-4-2-3-5-19(18)17-26-23/h2-7,14-17,30H,8-13H2,1H3/b27-22+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241560 (CHEMBL4064041) Show SMILES COCCOc1ccc2oc(c\c(=N/O)c2c1)-c1cc2ccccc2cn1 Show InChI InChI=1S/C21H18N2O4/c1-25-8-9-26-16-6-7-20-17(11-16)18(23-24)12-21(27-20)19-10-14-4-2-3-5-15(14)13-22-19/h2-7,10-13,24H,8-9H2,1H3/b23-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241561 (CHEMBL4085608) Show SMILES O\N=c1/cc(oc2ccc(cc12)C1CC1)-c1cc2ccccc2cn1 Show InChI InChI=1S/C21H16N2O2/c24-23-18-11-21(19-10-14-3-1-2-4-16(14)12-22-19)25-20-8-7-15(9-17(18)20)13-5-6-13/h1-4,7-13,24H,5-6H2/b23-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241562 (CHEMBL4103895) Show SMILES O\N=c1/cc(oc2cc(Br)ccc12)-c1cc2ccccc2cn1 Show InChI InChI=1S/C18H11BrN2O2/c19-13-5-6-14-15(21-22)9-18(23-17(14)8-13)16-7-11-3-1-2-4-12(11)10-20-16/h1-10,22H/b21-15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241563 (CHEMBL4085967) Show SMILES COc1ccc2oc(c\c(=N/O)c2c1)-c1cc2ccccc2cn1 Show InChI InChI=1S/C19H14N2O3/c1-23-14-6-7-18-15(9-14)16(21-22)10-19(24-18)17-8-12-4-2-3-5-13(12)11-20-17/h2-11,22H,1H3/b21-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241564 (CHEMBL4096136) Show SMILES O\N=c1/cc(oc2ccc(Br)cc12)-c1cc2ccccc2cn1 Show InChI InChI=1S/C18H11BrN2O2/c19-13-5-6-17-14(8-13)15(21-22)9-18(23-17)16-7-11-3-1-2-4-12(11)10-20-16/h1-10,22H/b21-15+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241565 (CHEMBL4082167) Show SMILES O\N=c1/cc(oc2ccc(CCCN3CCC(F)(F)CC3)cc12)-c1cc2sccc2cn1 Show InChI InChI=1S/C24H23F2N3O2S/c25-24(26)6-9-29(10-7-24)8-1-2-16-3-4-21-18(12-16)19(28-30)13-22(31-21)20-14-23-17(15-27-20)5-11-32-23/h3-5,11-15,30H,1-2,6-10H2/b28-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	106	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241566 (CHEMBL4100168) Show SMILES O\N=c1/cc(oc2ccc(CCCN3CCC(F)(F)C3)cc12)-c1cc2sccc2cn1 Show InChI InChI=1S/C23H21F2N3O2S/c24-23(25)6-8-28(14-23)7-1-2-15-3-4-20-17(10-15)18(27-29)11-21(30-20)19-12-22-16(13-26-19)5-9-31-22/h3-5,9-13,29H,1-2,6-8,14H2/b27-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241567 (CHEMBL4072094) Show SMILES O\N=c1/cc(oc2ccc(OCCCc3cccnc3)cc12)-c1cc2cccn2cn1 Show InChI InChI=1S/C24H20N4O3/c29-27-21-14-24(22-12-18-6-2-10-28(18)16-26-22)31-23-8-7-19(13-20(21)23)30-11-3-5-17-4-1-9-25-15-17/h1-2,4,6-10,12-16,29H,3,5,11H2/b27-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241568 (CHEMBL4100586) Show SMILES CN(C)C(=O)N1CC(C1)Oc1ccc2oc(c\c(=N/O)c2c1)-c1cc2cccn2cn1 Show InChI InChI=1S/C22H21N5O4/c1-25(2)22(28)27-11-16(12-27)30-15-5-6-20-17(9-15)18(24-29)10-21(31-20)19-8-14-4-3-7-26(14)13-23-19/h3-10,13,16,29H,11-12H2,1-2H3/b24-18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair

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