Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8798 (CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8798 (CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8807 (CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8798 (CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8798 (CHEMBL47787 | Pyrazolo[3,4-d]pyrimidine 6 | benzyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8793 (7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8806 ((1R,2R)-N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50145570 (1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8807 (CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8806 ((1R,2R)-N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8803 (CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8803 (CHEMBL295601 | N-(4-{4-amino-1-[4-(4-methylpiperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8805 (N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8794 (1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50145571 (1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8795 (1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-[4-(phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8794 (1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-(4-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8793 (7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8807 (CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8808 (3-{4-[(1H-indol-2-ylmethyl)amino]phenyl}-1-[4-(4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8802 (3-[4-(benzylamino)-3-methoxyphenyl]-1-[4-(4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50145570 (1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8807 (CHEMBL43773 | N-(4-{4-amino-1-[4-(4-methylpiperazi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM50145572 (3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8795 (1-[4-(4-methylpiperazin-1-yl)cyclohexyl]-3-[4-(phe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM8802 (3-[4-(benzylamino)-3-methoxyphenyl]-1-[4-(4-methyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50145571 (1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8804 (N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8797 (CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM8797 (CHEMBL297363 | N-(4-{4-amino-1-[4-(4-methylpiperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Bioresearch Center | Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor... | Bioorg Med Chem Lett 12: 1687-90 (2002) Article DOI: 10.1016/s0960-894x(02)00196-8 BindingDB Entry DOI: 10.7270/Q2154F84 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50145572 (3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Src protein tryrosine kinase activity with 1 mM ATP and biotinylated lck peptide | Bioorg Med Chem Lett 14: 2613-6 (2004) Article DOI: 10.1016/j.bmcl.2004.02.101 BindingDB Entry DOI: 10.7270/Q2M61JQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287470 (US9567339, Example K.1.1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287471 (US9567339, Example M.1.1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287472 (US9567339, Example M.1.2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287475 (US9567339, Example O.1.3*) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287476 (US9567339, Example O.1.4*) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287477 (US9567339, Example O.1.5*) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287489 (US9567339, Example O.1.19*) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287495 (US9567339, Example O.1.25*) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287496 (US9567339, Example O.1.26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287500 (US9567339, Example U.1.2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287503 (US9567339, Example 5.2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287506 (US9567339, Example 4.1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287507 (US9567339, Example 4.2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287151 (US9567339, Example A.1.2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287153 (US9567339, Example A.1.4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287154 (US9567339, Example A.1.5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287155 (US9567339, Example A.1.6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287156 (US9567339, Example A.1.7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK [393-659] (Homo sapiens (Human)) | BDBM287157 (US9567339, Example A.1.8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 6.5 | 25 |
AbbVie Inc. US Patent | Assay Description The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri... | US Patent US9567339 (2017) BindingDB Entry DOI: 10.7270/Q2P2715T | |||||||||||
More data for this Ligand-Target Pair |
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