Compile Data Set for Download or QSAR

Found 876 hits with Last Name = 'ginn' and Initial = 'jd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169504 (US9079880, 37) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C28H30N6O2S/c1-33(2)22-11-12-23-25(16-22)37-27(31-23)32-26(35)20-8-4-7-19(15-20)24-10-5-13-34(24)28(36)30-21-9-3-6-18(14-21)17-29/h3-4,6-9,14-15,22,24H,5,10-13,16H2,1-2H3,(H,30,36)(H,31,32,35)/t22-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169498 (US9079880, 31) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(OC)c3)sc2C1 |r| Show InChI InChI=1S/C28H34N4O4S/c1-5-13-29-21-10-11-22-25(16-21)37-28(31-22)32-27(34)19-8-6-7-18(14-19)17(2)30-26(33)20-9-12-23(35-3)24(15-20)36-4/h6-9,12,14-15,17,21,29H,5,10-11,13,16H2,1-4H3,(H,30,33)(H,31,32,34)/t17-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169487 (US9079880, 20) Show SMILES N[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C26H26N6O2S/c27-15-16-4-1-7-20(12-16)29-26(34)32-11-3-8-22(32)17-5-2-6-18(13-17)24(33)31-25-30-21-10-9-19(28)14-23(21)35-25/h1-2,4-7,12-13,19,22H,3,8-11,14,28H2,(H,29,34)(H,30,31,33)/t19-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.390	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169502 (US9079880, 35) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(C)c3)sc2C1 |r| Show InChI InChI=1S/C28H34N4O3S/c1-5-13-29-22-10-11-23-25(16-22)36-28(31-23)32-27(34)20-8-6-7-19(15-20)18(3)30-26(33)21-9-12-24(35-4)17(2)14-21/h6-9,12,14-15,18,22,29H,5,10-11,13,16H2,1-4H3,(H,30,33)(H,31,32,34)/t18-,22+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169500 (US9079880, 33) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(Cl)c3)sc2C1 |r| Show InChI InChI=1S/C27H31ClN4O3S/c1-4-12-29-20-9-10-22-24(15-20)36-27(31-22)32-26(34)18-7-5-6-17(13-18)16(2)30-25(33)19-8-11-23(35-3)21(28)14-19/h5-8,11,13-14,16,20,29H,4,9-10,12,15H2,1-3H3,(H,30,33)(H,31,32,34)/t16-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169506 (US9079880, 39) Show SMILES O=C(Nc1cccc(c1)C#N)N1CCC[C@@H]1c1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1 |r| Show InChI InChI=1S/C30H32N6O3S/c31-19-20-4-1-7-23(16-20)32-30(38)36-11-3-8-26(36)21-5-2-6-22(17-21)28(37)34-29-33-25-10-9-24(18-27(25)40-29)35-12-14-39-15-13-35/h1-2,4-7,16-17,24,26H,3,8-15,18H2,(H,32,38)(H,33,34,37)/t24-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169511 (US9079880, 44) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3ccc(cc3)C(N)=O)sc2C1 |r| Show InChI InChI=1S/C26H28N6O3S/c1-31-13-11-20-22(15-31)36-25(29-20)30-24(34)18-5-2-4-17(14-18)21-6-3-12-32(21)26(35)28-19-9-7-16(8-10-19)23(27)33/h2,4-5,7-10,14,21H,3,6,11-13,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169563 (US9079880, 96) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cc([nH]n3)-c3ccncc3)sc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169490 (US9079880, 23) Show SMILES CN1CCc2nc(NC(=O)c3cccc(OCC(=O)Nc4ccc5[nH]ncc5c4)c3)sc2C1 Show InChI InChI=1S/C23H22N6O3S/c1-29-8-7-19-20(12-29)33-23(26-19)27-22(31)14-3-2-4-17(10-14)32-13-21(30)25-16-5-6-18-15(9-16)11-24-28-18/h2-6,9-11H,7-8,12-13H2,1H3,(H,24,28)(H,25,30)(H,26,27,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169496 (US9079880, 29) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C29H32N6O2S/c1-2-13-31-22-11-12-24-26(17-22)38-28(33-24)34-27(36)21-8-4-7-20(16-21)25-10-5-14-35(25)29(37)32-23-9-3-6-19(15-23)18-30/h3-4,6-9,15-16,22,25,31H,2,5,10-14,17H2,1H3,(H,32,37)(H,33,34,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169502 (US9079880, 35) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(C)c3)sc2C1 |r| Show InChI InChI=1S/C28H34N4O3S/c1-5-13-29-22-10-11-23-25(16-22)36-28(31-23)32-27(34)20-8-6-7-19(15-20)18(3)30-26(33)21-9-12-24(35-4)17(2)14-21/h6-9,12,14-15,18,22,29H,5,10-11,13,16H2,1-4H3,(H,30,33)(H,31,32,34)/t18-,22+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169498 (US9079880, 31) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(OC)c3)sc2C1 |r| Show InChI InChI=1S/C28H34N4O4S/c1-5-13-29-21-10-11-22-25(16-21)37-28(31-22)32-27(34)19-8-6-7-18(14-19)17(2)30-26(33)20-9-12-23(35-3)24(15-20)36-4/h6-9,12,14-15,17,21,29H,5,10-11,13,16H2,1-4H3,(H,30,33)(H,31,32,34)/t17-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169489 (US9079880, 22) Show SMILES N[C@@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C26H26N6O2S/c27-15-16-4-1-7-20(12-16)29-26(34)32-11-3-8-22(32)17-5-2-6-18(13-17)24(33)31-25-30-21-10-9-19(28)14-23(21)35-25/h1-2,4-7,12-13,19,22H,3,8-11,14,28H2,(H,29,34)(H,30,31,33)/t19-,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169500 (US9079880, 33) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(Cl)c3)sc2C1 |r| Show InChI InChI=1S/C27H31ClN4O3S/c1-4-12-29-20-9-10-22-24(15-20)36-27(31-22)32-26(34)18-7-5-6-17(13-18)16(2)30-25(33)19-8-11-23(35-3)21(28)14-19/h5-8,11,13-14,16,20,29H,4,9-10,12,15H2,1-3H3,(H,30,33)(H,31,32,34)/t16-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169559 (US9079880, 92) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3csc(n3)-c3cccnc3)sc2C1 |r| Show InChI InChI=1S/C29H30N6O2S2/c1-34(2)21-10-11-22-25(15-21)39-29(32-22)33-26(36)19-7-3-6-18(14-19)24-9-5-13-35(24)28(37)23-17-38-27(31-23)20-8-4-12-30-16-20/h3-4,6-8,12,14,16-17,21,24H,5,9-11,13,15H2,1-2H3,(H,32,33,36)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169511 (US9079880, 44) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3ccc(cc3)C(N)=O)sc2C1 |r| Show InChI InChI=1S/C26H28N6O3S/c1-31-13-11-20-22(15-31)36-25(29-20)30-24(34)18-5-2-4-17(14-18)21-6-3-12-32(21)26(35)28-19-9-7-16(8-10-19)23(27)33/h2,4-5,7-10,14,21H,3,6,11-13,15H2,1H3,(H2,27,33)(H,28,35)(H,29,30,34)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169496 (US9079880, 29) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C29H32N6O2S/c1-2-13-31-22-11-12-24-26(17-22)38-28(33-24)34-27(36)21-8-4-7-20(16-21)25-10-5-14-35(25)29(37)32-23-9-3-6-19(15-23)18-30/h3-4,6-9,15-16,22,25,31H,2,5,10-14,17H2,1H3,(H,32,37)(H,33,34,36)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169493 (US9079880, 26) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-c3ccncc3)sc2C1 |r| Show InChI InChI=1S/C30H29N5O2S/c1-34-17-13-25-27(19-34)38-30(32-25)33-28(36)24-5-2-4-23(18-24)26-6-3-16-35(26)29(37)22-9-7-20(8-10-22)21-11-14-31-15-12-21/h2,4-5,7-12,14-15,18,26H,3,6,13,16-17,19H2,1H3,(H,32,33,36)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169476 (US9079880, 9) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(OCC(=O)Nc4ccc(cc4)C#N)c3)sc2C1 |r| Show InChI InChI=1S/C25H25N5O3S/c1-30(2)19-10-11-21-22(13-19)34-25(28-21)29-24(32)17-4-3-5-20(12-17)33-15-23(31)27-18-8-6-16(14-26)7-9-18/h3-9,12,19H,10-11,13,15H2,1-2H3,(H,27,31)(H,28,29,32)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169571 (US9079880, 104) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cn4cc(ccc4n3)C(N)=O)sc2C1 |r| Show InChI InChI=1S/C29H31N7O3S/c1-34(2)20-9-10-21-24(14-20)40-29(32-21)33-27(38)18-6-3-5-17(13-18)23-7-4-12-36(23)28(39)22-16-35-15-19(26(30)37)8-11-25(35)31-22/h3,5-6,8,11,13,15-16,20,23H,4,7,9-10,12,14H2,1-2H3,(H2,30,37)(H,32,33,38)/t20-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169549 (US9079880, 82) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1cn2ccc(cc2n1)C#N |r| Show InChI InChI=1S/C31H31N7O3S/c32-18-20-8-10-37-19-25(33-28(37)15-20)30(40)38-9-2-5-26(38)21-3-1-4-22(16-21)29(39)35-31-34-24-7-6-23(17-27(24)42-31)36-11-13-41-14-12-36/h1,3-4,8,10,15-16,19,23,26H,2,5-7,9,11-14,17H2,(H,34,35,39)/t23-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169487 (US9079880, 20) Show SMILES N[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C26H26N6O2S/c27-15-16-4-1-7-20(12-16)29-26(34)32-11-3-8-22(32)17-5-2-6-18(13-17)24(33)31-25-30-21-10-9-19(28)14-23(21)35-25/h1-2,4-7,12-13,19,22H,3,8-11,14,28H2,(H,29,34)(H,30,31,33)/t19-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169573 (US9079880, 106) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cccc(c3)-c3cn[nH]c3)sc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169545 (US9079880, 78) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cccc(c3)-c3cn[nH]c3)sc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169561 (US9079880, 94) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3csc(n3)-c3ccncc3)sc2C1 |r| Show InChI InChI=1S/C29H30N6O2S2/c1-34(2)21-8-9-22-25(16-21)39-29(32-22)33-26(36)20-6-3-5-19(15-20)24-7-4-14-35(24)28(37)23-17-38-27(31-23)18-10-12-30-13-11-18/h3,5-6,10-13,15,17,21,24H,4,7-9,14,16H2,1-2H3,(H,32,33,36)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169567 (US9079880, 100) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc4cc(O)ccc4c3)sc2C1 |r| Show InChI InChI=1S/C31H32N4O3S/c1-34(2)24-11-13-26-28(18-24)39-31(32-26)33-29(37)22-6-3-5-21(16-22)27-7-4-14-35(27)30(38)23-9-8-20-17-25(36)12-10-19(20)15-23/h3,5-6,8-10,12,15-17,24,27,36H,4,7,11,13-14,18H2,1-2H3,(H,32,33,37)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169507 (US9079880, 40) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc4cc(O)ccc4c3)sc2C1 |r| Show InChI InChI=1S/C29H28N4O3S/c1-32-13-11-24-26(17-32)37-29(30-24)31-27(35)21-5-2-4-20(15-21)25-6-3-12-33(25)28(36)22-8-7-19-16-23(34)10-9-18(19)14-22/h2,4-5,7-10,14-16,25,34H,3,6,11-13,17H2,1H3,(H,30,31,35)/t25-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169557 (US9079880, 90) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-c3cnco3)sc2C1 |r| Show InChI InChI=1S/C30H31N5O3S/c1-34(2)23-12-13-24-27(16-23)39-30(32-24)33-28(36)22-6-3-5-21(15-22)25-7-4-14-35(25)29(37)20-10-8-19(9-11-20)26-17-31-18-38-26/h3,5-6,8-11,15,17-18,23,25H,4,7,12-14,16H2,1-2H3,(H,32,33,36)/t23-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169545 (US9079880, 78) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cccc(c3)-c3cn[nH]c3)sc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169476 (US9079880, 9) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(OCC(=O)Nc4ccc(cc4)C#N)c3)sc2C1 |r| Show InChI InChI=1S/C25H25N5O3S/c1-30(2)19-10-11-21-22(13-19)34-25(28-21)29-24(32)17-4-3-5-20(12-17)33-15-23(31)27-18-8-6-16(14-26)7-9-18/h3-9,12,19H,10-11,13,15H2,1-2H3,(H,27,31)(H,28,29,32)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169517 (US9079880, 50) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3nnn(-c4nonc4N)c3-c3ccccc3)sc2C1 |r| Show InChI InChI=1S/C31H32N10O3S/c1-39(2)21-13-14-22-24(17-21)45-31(33-22)34-29(42)20-11-6-10-19(16-20)23-12-7-15-40(23)30(43)25-26(18-8-4-3-5-9-18)41(38-35-25)28-27(32)36-44-37-28/h3-6,8-11,16,21,23H,7,12-15,17H2,1-2H3,(H2,32,36)(H,33,34,42)/t21-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169591 (US9079880, 124) Show SMILES NC(=O)c1ccc2nc(cn2c1)C(=O)N1CCC[C@@H]1c1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1 |r| Show InChI InChI=1S/C31H33N7O4S/c32-28(39)21-6-9-27-33-24(18-37(27)17-21)30(41)38-10-2-5-25(38)19-3-1-4-20(15-19)29(40)35-31-34-23-8-7-22(16-26(23)43-31)36-11-13-42-14-12-36/h1,3-4,6,9,15,17-18,22,25H,2,5,7-8,10-14,16H2,(H2,32,39)(H,34,35,40)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169575 (US9079880, 108) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc4[nH]c(=O)ccc4c3)sc2C1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169607 (US9079880, 140) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1cccc(c1)-c1cn[nH]c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169597 (US9079880, 130) Show SMILES Oc1ccc2cc(ccc2c1)C(=O)N1CCC[C@@H]1c1cccc(c1)C(=O)Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1 |r| Show InChI InChI=1S/C33H34N4O4S/c38-27-10-8-21-17-25(7-6-22(21)19-27)32(40)37-12-2-5-29(37)23-3-1-4-24(18-23)31(39)35-33-34-28-11-9-26(20-30(28)42-33)36-13-15-41-16-14-36/h1,3-4,6-8,10,17-19,26,29,38H,2,5,9,11-16,20H2,(H,34,35,39)/t26-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169585 (US9079880, 118) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1ccc(cc1)-c1cnco1 |r| Show InChI InChI=1S/C32H33N5O4S/c38-30(35-32-34-26-11-10-25(18-29(26)42-32)36-13-15-40-16-14-36)24-4-1-3-23(17-24)27-5-2-12-37(27)31(39)22-8-6-21(7-9-22)28-19-33-20-41-28/h1,3-4,6-9,17,19-20,25,27H,2,5,10-16,18H2,(H,34,35,38)/t25-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169541 (US9079880, 74) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cn4cc(ccc4n3)C(N)=O)sc2C1 |r| Show InChI InChI=1S/C27H27N7O3S/c1-32-11-9-19-22(15-32)38-27(30-19)31-25(36)17-5-2-4-16(12-17)21-6-3-10-34(21)26(37)20-14-33-13-18(24(28)35)7-8-23(33)29-20/h2,4-5,7-8,12-14,21H,3,6,9-11,15H2,1H3,(H2,28,35)(H,30,31,36)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169603 (US9079880, 136) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1csc(n1)-c1cccnc1 |r| Show InChI InChI=1S/C31H32N6O3S2/c38-28(35-31-34-24-9-8-23(17-27(24)42-31)36-12-14-40-15-13-36)21-5-1-4-20(16-21)26-7-3-11-37(26)30(39)25-19-41-29(33-25)22-6-2-10-32-18-22/h1-2,4-6,10,16,18-19,23,26H,3,7-9,11-15,17H2,(H,34,35,38)/t23-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169599 (US9079880, 132) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1ccc(cc1)-c1ccncc1 |r| Show InChI InChI=1S/C34H35N5O3S/c40-32(37-34-36-29-11-10-28(22-31(29)43-34)38-17-19-42-20-18-38)27-4-1-3-26(21-27)30-5-2-16-39(30)33(41)25-8-6-23(7-9-25)24-12-14-35-15-13-24/h1,3-4,6-9,12-15,21,28,30H,2,5,10-11,16-20,22H2,(H,36,37,40)/t28-,30+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169569 (US9079880, 102) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-n3ccnc3)sc2C1 |r| Show InChI InChI=1S/C30H32N6O2S/c1-34(2)24-12-13-25-27(18-24)39-30(32-25)33-28(37)22-6-3-5-21(17-22)26-7-4-15-36(26)29(38)20-8-10-23(11-9-20)35-16-14-31-19-35/h3,5-6,8-11,14,16-17,19,24,26H,4,7,12-13,15,18H2,1-2H3,(H,32,33,37)/t24-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169537 (US9079880, 70) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-c3cnco3)sc2C1 |r| Show InChI InChI=1S/C28H27N5O3S/c1-32-13-11-22-25(16-32)37-28(30-22)31-26(34)21-5-2-4-20(14-21)23-6-3-12-33(23)27(35)19-9-7-18(8-10-19)24-15-29-17-36-24/h2,4-5,7-10,14-15,17,23H,3,6,11-13,16H2,1H3,(H,30,31,34)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169489 (US9079880, 22) Show SMILES N[C@@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)Nc3cccc(c3)C#N)sc2C1 |r| Show InChI InChI=1S/C26H26N6O2S/c27-15-16-4-1-7-20(12-16)29-26(34)32-11-3-8-22(32)17-5-2-6-18(13-17)24(33)31-25-30-21-10-9-19(28)14-23(21)35-25/h1-2,4-7,12-13,19,22H,3,8-11,14,28H2,(H,29,34)(H,30,31,33)/t19-,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169601 (US9079880, 134) Show SMILES Nc1nonc1-n1nnc(C(=O)N2CCC[C@@H]2c2cccc(c2)C(=O)Nc2nc3CC[C@@H](Cc3s2)N2CCOCC2)c1-c1ccccc1 |r| Show InChI InChI=1S/C33H34N10O4S/c34-29-30(39-47-38-29)43-28(20-6-2-1-3-7-20)27(37-40-43)32(45)42-13-5-10-25(42)21-8-4-9-22(18-21)31(44)36-33-35-24-12-11-23(19-26(24)48-33)41-14-16-46-17-15-41/h1-4,6-9,18,23,25H,5,10-17,19H2,(H2,34,38)(H,35,36,44)/t23-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169593 (US9079880, 126) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1ccc2[nH]c(=O)ccc2c1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169515 (US9079880, 48) Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3sc(nc3C)-c3ccncc3)sc2C1 |r| Show InChI InChI=1S/C30H32N6O2S2/c1-18-26(40-28(32-18)19-11-13-31-14-12-19)29(38)36-15-5-8-24(36)20-6-4-7-21(16-20)27(37)34-30-33-23-10-9-22(35(2)3)17-25(23)39-30/h4,6-7,11-14,16,22,24H,5,8-10,15,17H2,1-3H3,(H,33,34,37)/t22-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169469 (US9079880, 2) Show SMILES COc1ccc(cc1Cl)C(=O)N[C@H](C1CC1)c1cccc(c1)C(=O)Nc1nc2CCN(C)Cc2s1 |r| Show InChI InChI=1S/C26H27ClN4O3S/c1-31-11-10-20-22(14-31)35-26(28-20)30-25(33)17-5-3-4-16(12-17)23(15-6-7-15)29-24(32)18-8-9-21(34-2)19(27)13-18/h3-5,8-9,12-13,15,23H,6-7,10-11,14H2,1-2H3,(H,29,32)(H,28,30,33)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169577 (US9079880, 110) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C32H34N6O3S/c33-20-23-6-2-7-28-25(23)11-13-38(28)32(40)37-12-3-8-27(37)21-4-1-5-22(18-21)30(39)35-31-34-26-10-9-24(19-29(26)42-31)36-14-16-41-17-15-36/h1-2,4-7,18,24,27H,3,8-17,19H2,(H,34,35,39)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169577 (US9079880, 110) Show SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C32H34N6O3S/c33-20-23-6-2-7-28-25(23)11-13-38(28)32(40)37-12-3-8-27(37)21-4-1-5-22(18-21)30(39)35-31-34-26-10-9-24(19-29(26)42-31)36-14-16-41-17-15-36/h1-2,4-7,18,24,27H,3,8-17,19H2,(H,34,35,39)/t24-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169615 (US9079880, 148) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cn4ccc(cc4n3)C#N)sc2C1 |r| Show InChI InChI=1S/C27H25N7O2S/c1-32-10-8-20-23(16-32)37-27(30-20)31-25(35)19-5-2-4-18(13-19)22-6-3-9-34(22)26(36)21-15-33-11-7-17(14-28)12-24(33)29-21/h2,4-5,7,11-13,15,22H,3,6,8-10,16H2,1H3,(H,30,31,35)/t22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50196941 (CHEMBL246365 | N2-(2-chlorobenzyl)-N4-((3-(aminome...) Show SMILES NCC1CCCC(CNc2nc(NCc3ccccc3Cl)ncc2[N+]([O-])=O)C1 |w:6.6,2.1| Show InChI InChI=1S/C19H25ClN6O2/c20-16-7-2-1-6-15(16)11-23-19-24-12-17(26(27)28)18(25-19)22-10-14-5-3-4-13(8-14)9-21/h1-2,6-7,12-14H,3-5,8-11,21H2,(H2,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PKCtheta by FP assay				Bioorg Med Chem Lett 17: 225-30 (2006) Article DOI: 10.1016/j.bmcl.2006.09.056 BindingDB Entry DOI: 10.7270/Q2PC3211
					More data for this Ligand-Target Pair

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