BindingDB PrimarySearch

Found 11 hits with Last Name = 'gromova' and Initial = 'e'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA (cytosine-5)-methyltransferase 3A (Homo sapiens (Human))	BDBM50430056 (CHEMBL2336409 \| SGI-1027) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of human C-terminal DNMT3A (623 to 908 residues) using 5'-biotin labeled oligonucleotide as substrate measured after 1 hr				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of murine DNMT3A catalytic domain-mediated DNA methylation using 5'-6FAM-tagged 30-mer duplex DNA (17 AT bp) as substrate preincubated for...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of murine DNMT3A catalytic domain-mediated DNA methylation using 5'-6FAM-tagged 30-mer duplex DNA (22 AT bp) as substrate preincubated for...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Homo sapiens (Human))	BDBM50544059 (CHEMBL4171551) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to DNMT3A catalytic domain (unknown origin) assessed as inhibition of enzyme-mediated DNA methylation preincubated for 1 hr followed...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of murine DNMT3A catalytic domain-mediated DNA methylation using 5'-6FAM-tagged 30-mer duplex DNA (17 AT bp) as substrate preincubated for...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 30 uM using 30-mer duplex DNA (22 AT bp) as substrate ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 15 uM using 30-mer duplex DNA (22 AT bp) as substrate ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 5 uM using 30-mer duplex DNA (22 AT bp) as substrate p...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 15 uM using 30-mer duplex DNA (17 AT bp) as substrate ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 5 uM using 30-mer duplex DNA (17 AT bp) as substrate p...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 3A (Mus musculus)	BDBM50544058 (CHEMBL4640631) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Binding affinity to murine DNMT3A catalytic domain assessed as enzyme-DNA complex formation at 30 uM using 30-mer duplex DNA (17 AT bp) as substrate ...				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair