Compile Data Set for Download or QSAR

Found 327 hits with Last Name = 'hung' and Initial = 'aw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455611 (CHEMBL4212424) Show SMILES COc1cc2CC(CF)NCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C10H14N2O3S2/c1-2-3-12-6-8-4-7-5-9(17(11,13)14)15-10(7)16-8/h4-5,12H,2-3,6H2,1H3,(H2,11,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455569 (CHEMBL4202753) Show SMILES COc1cc2CCNCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O/c1-30-23-12-15-2-6-25-13-17(15)10-20(23)21-14-28-29-9-5-16(11-22(21)29)18-3-7-26-24-19(18)4-8-27-24/h3-5,7-12,14,25H,2,6,13H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455593 (CHEMBL4208685) Show SMILES COc1cc2CC(C)NCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C25H23N5O/c1-15-9-17-12-24(31-2)21(10-18(17)13-28-15)22-14-29-30-8-5-16(11-23(22)30)19-3-6-26-25-20(19)4-7-27-25/h3-8,10-12,14-15,28H,9,13H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455592 (CHEMBL4206065) Show SMILES COc1cc2CN(C)Cc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O/c1-28-13-16-9-20(23(30-2)11-17(16)14-28)21-12-27-29-8-5-15(10-22(21)29)18-3-6-25-24-19(18)4-7-26-24/h3-12H,13-14H2,1-2H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455602 (CHEMBL4216507) Show SMILES COc1cc2CNCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O/c1-29-22-10-16-12-24-11-15(16)8-19(22)20-13-27-28-7-4-14(9-21(20)28)17-2-5-25-23-18(17)3-6-26-23/h2-10,13,24H,11-12H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C zeta type (Homo sapiens (Human))	BDBM50455589 (CHEMBL4213984) Show SMILES COc1cc2CNCc2cc1-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O/c1-29-22-10-16-12-24-11-15(16)9-21(22)28-13-27-19-3-2-14(8-20(19)28)17-4-6-25-23-18(17)5-7-26-23/h2-10,13,24H,11-12H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-zeta expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520279 (CHEMBL4442209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1c(C)n[nH]c1C Show InChI InChI=1S/C20H22N4O2/c1-11(2)26-18-8-14(5-6-17(18)20(21)25)15-7-16(10-22-9-15)19-12(3)23-24-13(19)4/h5-11H,1-4H3,(H2,21,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520278 (CHEMBL4569209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cn[nH]c1C Show InChI InChI=1S/C19H20N4O2/c1-11(2)25-18-7-13(4-5-16(18)19(20)24)14-6-15(9-21-8-14)17-10-22-23-12(17)3/h4-11H,1-3H3,(H2,20,24)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM31085 (1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...) Show SMILES CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 Show InChI InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK2 (unknown origin)				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455566 (CHEMBL4208028) Show SMILES COc1cc2CNCc2cc1-n1cnc2cnc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C22H18N6O/c1-29-21-7-14-10-23-9-13(14)6-20(21)28-12-27-18-11-26-17(8-19(18)28)15-2-4-24-22-16(15)3-5-25-22/h2-8,11-12,23H,9-10H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520279 (CHEMBL4442209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1c(C)n[nH]c1C Show InChI InChI=1S/C20H22N4O2/c1-11(2)26-18-8-14(5-6-17(18)20(21)25)15-7-16(10-22-9-15)19-12(3)23-24-13(19)4/h5-11H,1-4H3,(H2,21,25)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520296 (CHEMBL4588193) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C(C)C Show InChI InChI=1S/C21H24N4O2/c1-13(2)25-12-18(11-24-25)17-7-16(9-23-10-17)15-5-6-19(21(22)26)20(8-15)27-14(3)4/h5-14H,1-4H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520256 (CHEMBL4443472) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C1CCOC1 Show InChI InChI=1S/C22H24N4O3/c1-14(2)29-21-8-15(3-4-20(21)22(23)27)16-7-17(10-24-9-16)18-11-25-26(12-18)19-5-6-28-13-19/h3-4,7-12,14,19H,5-6,13H2,1-2H3,(H2,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455611 (CHEMBL4212424) Show SMILES COc1cc2CC(CF)NCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C10H14N2O3S2/c1-2-3-12-6-8-4-7-5-9(17(11,13)14)15-10(7)16-8/h4-5,12H,2-3,6H2,1H3,(H2,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50455611 (CHEMBL4212424) Show SMILES COc1cc2CC(CF)NCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C10H14N2O3S2/c1-2-3-12-6-8-4-7-5-9(17(11,13)14)15-10(7)16-8/h4-5,12H,2-3,6H2,1H3,(H2,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455589 (CHEMBL4213984) Show SMILES COc1cc2CNCc2cc1-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O/c1-29-22-10-16-12-24-11-15(16)9-21(22)28-13-27-19-3-2-14(8-20(19)28)17-4-6-25-23-18(17)5-7-26-23/h2-10,13,24H,11-12H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520278 (CHEMBL4569209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cn[nH]c1C Show InChI InChI=1S/C19H20N4O2/c1-11(2)25-18-7-13(4-5-16(18)19(20)24)14-6-15(9-21-8-14)17-10-22-23-12(17)3/h4-11H,1-3H3,(H2,20,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520292 (CHEMBL4462099) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1c[nH]nc1C1CC1 Show InChI InChI=1S/C21H22N4O2/c1-12(2)27-19-8-14(5-6-17(19)21(22)26)15-7-16(10-23-9-15)18-11-24-25-20(18)13-3-4-13/h5-13H,3-4H2,1-2H3,(H2,22,26)(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520252 (CHEMBL4440223) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(C)c1C Show InChI InChI=1S/C20H22N4O2/c1-12(2)26-19-8-14(5-6-17(19)20(21)25)15-7-16(10-22-9-15)18-11-23-24(4)13(18)3/h5-12H,1-4H3,(H2,21,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455593 (CHEMBL4208685) Show SMILES COc1cc2CC(C)NCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C25H23N5O/c1-15-9-17-12-24(31-2)21(10-18(17)13-28-15)22-14-29-30-8-5-16(11-23(22)30)19-3-6-26-25-20(19)4-7-27-25/h3-8,10-12,14-15,28H,9,13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455594 (CHEMBL4212934) Show SMILES COc1cc2CNCc2cc1-n1cnc2ccc(nc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C22H18N6O/c1-29-20-9-14-11-23-10-13(14)8-19(20)28-12-26-18-3-2-17(27-22(18)28)15-4-6-24-21-16(15)5-7-25-21/h2-9,12,23H,10-11H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455569 (CHEMBL4202753) Show SMILES COc1cc2CCNCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O/c1-30-23-12-15-2-6-25-13-17(15)10-20(23)21-14-28-29-9-5-16(11-22(21)29)18-3-7-26-24-19(18)4-8-27-24/h3-5,7-12,14,25H,2,6,13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520289 (CHEMBL4587472) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1nn[nH]n1 Show InChI InChI=1S/C16H16N6O2/c1-9(2)24-14-6-10(3-4-13(14)15(17)23)11-5-12(8-18-7-11)16-19-21-22-20-16/h3-9H,1-2H3,(H2,17,23)(H,19,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520296 (CHEMBL4588193) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C(C)C Show InChI InChI=1S/C21H24N4O2/c1-13(2)25-12-18(11-24-25)17-7-16(9-23-10-17)15-5-6-19(21(22)26)20(8-15)27-14(3)4/h5-14H,1-4H3,(H2,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520253 (CHEMBL4587832) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C1COC1 Show InChI InChI=1S/C21H22N4O3/c1-13(2)28-20-6-14(3-4-19(20)21(22)26)15-5-16(8-23-7-15)17-9-24-25(10-17)18-11-27-12-18/h3-10,13,18H,11-12H2,1-2H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50172078 (LY-2801653 | Merestinib) Show SMILES Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19/h3-16H,1-2H3,(H,33,34)(H,36,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK2 (unknown origin)				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455602 (CHEMBL4216507) Show SMILES COc1cc2CNCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O/c1-29-22-10-16-12-24-11-15(16)8-19(22)20-13-27-28-7-4-14(9-21(20)28)17-2-5-25-23-18(17)3-6-26-23/h2-10,13,24H,11-12H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455610 (CHEMBL4211722) Show SMILES COc1cc2CNCc2cc1-c1cnn2ccc(nc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C22H18N6O/c1-29-20-9-14-11-23-10-13(14)8-17(20)18-12-26-28-7-4-19(27-22(18)28)15-2-5-24-21-16(15)3-6-25-21/h2-9,12,23H,10-11H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520252 (CHEMBL4440223) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(C)c1C Show InChI InChI=1S/C20H22N4O2/c1-12(2)26-19-8-14(5-6-17(19)20(21)25)15-7-16(10-22-9-15)18-11-23-24(4)13(18)3/h5-12H,1-4H3,(H2,21,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520256 (CHEMBL4443472) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C1CCOC1 Show InChI InChI=1S/C22H24N4O3/c1-14(2)29-21-8-15(3-4-20(21)22(23)27)16-7-17(10-24-9-16)18-11-25-26(12-18)19-5-6-28-13-19/h3-4,7-12,14,19H,5-6,13H2,1-2H3,(H2,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455588 (CHEMBL4208982) Show SMILES COc1cc(CN)ccc1-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C22H19N5O/c1-28-21-10-14(12-23)2-5-19(21)27-13-26-18-4-3-15(11-20(18)27)16-6-8-24-22-17(16)7-9-25-22/h2-11,13H,12,23H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520292 (CHEMBL4462099) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1c[nH]nc1C1CC1 Show InChI InChI=1S/C21H22N4O2/c1-12(2)27-19-8-14(5-6-17(19)21(22)26)15-7-16(10-23-9-15)18-11-24-25-20(18)13-3-4-13/h5-13H,3-4H2,1-2H3,(H2,22,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50172078 (LY-2801653 | Merestinib) Show SMILES Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19/h3-16H,1-2H3,(H,33,34)(H,36,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK1 (unknown origin)				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455592 (CHEMBL4206065) Show SMILES COc1cc2CN(C)Cc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O/c1-28-13-16-9-20(23(30-2)11-17(16)14-28)21-12-27-29-8-5-15(10-22(21)29)18-3-6-25-24-19(18)4-7-26-24/h3-12H,13-14H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520276 (CHEMBL4457274) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(C)c1 Show InChI InChI=1S/C19H20N4O2/c1-12(2)25-18-7-13(4-5-17(18)19(20)24)14-6-15(9-21-8-14)16-10-22-23(3)11-16/h4-12H,1-3H3,(H2,20,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human))	BDBM50520279 (CHEMBL4442209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1c(C)n[nH]c1C Show InChI InChI=1S/C20H22N4O2/c1-11(2)26-18-8-14(5-6-17(18)20(21)25)15-7-16(10-22-9-15)19-12(3)23-24-13(19)4/h5-11H,1-4H3,(H2,21,25)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50455593 (CHEMBL4208685) Show SMILES COc1cc2CC(C)NCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C25H23N5O/c1-15-9-17-12-24(31-2)21(10-18(17)13-28-15)22-14-29-30-8-5-16(11-23(22)30)19-3-6-26-25-20(19)4-7-27-25/h3-8,10-12,14-15,28H,9,13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human))	BDBM50520253 (CHEMBL4587832) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C1COC1 Show InChI InChI=1S/C21H22N4O3/c1-13(2)28-20-6-14(3-4-19(20)21(22)26)15-5-16(8-23-7-15)17-9-24-25(10-17)18-11-27-12-18/h3-10,13,18H,11-12H2,1-2H3,(H2,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520253 (CHEMBL4587832) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cnn(c1)C1COC1 Show InChI InChI=1S/C21H22N4O3/c1-13(2)28-20-6-14(3-4-19(20)21(22)26)15-5-16(8-23-7-15)17-9-24-25(10-17)18-11-27-12-18/h3-10,13,18H,11-12H2,1-2H3,(H2,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50455602 (CHEMBL4216507) Show SMILES COc1cc2CNCc2cc1-c1cnn2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O/c1-29-22-10-16-12-24-11-15(16)8-19(22)20-13-27-28-7-4-14(9-21(20)28)17-2-5-25-23-18(17)3-6-26-23/h2-10,13,24H,11-12H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-epsilon expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate a...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455566 (CHEMBL4208028) Show SMILES COc1cc2CNCc2cc1-n1cnc2cnc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C22H18N6O/c1-29-21-7-14-10-23-9-13(14)6-20(21)28-12-27-18-11-26-17(8-19(18)28)15-2-4-24-22-16(15)3-5-25-22/h2-8,11-12,23H,9-10H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50526595 (CHEMBL4517782) Show SMILES Nc1ncc(nc1C(=O)Nc1ccncc1)-c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C20H21N7O/c21-19-18(20(28)25-15-4-6-22-7-5-15)26-17(13-24-19)14-2-1-3-16(12-14)27-10-8-23-9-11-27/h1-7,12-13,23H,8-11H2,(H2,21,24)(H,22,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
ASTAR Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR...				ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50455589 (CHEMBL4213984) Show SMILES COc1cc2CNCc2cc1-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O/c1-29-22-10-16-12-24-11-15(16)9-21(22)28-13-27-19-3-2-14(8-20(19)28)17-4-6-25-23-18(17)5-7-26-23/h2-10,13,24H,11-12H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-alpha expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate aft...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50455568 (CHEMBL4215492) Show SMILES C1NCc2cc(ccc12)-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C22H17N5/c1-3-17(9-16-12-23-11-15(1)16)27-13-26-20-4-2-14(10-21(20)27)18-5-7-24-22-19(18)6-8-25-22/h1-10,13,23H,11-12H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50578087 (CHEMBL4871523) Show SMILES COc1ccc(cc1)-n1cc(cn1)-c1n[nH]c2cc(Cl)c(N[C@@H]3CCNC3)cc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Axl (unknown origin) using 5'FAM labeled KKKKEEIYFFF-NH2 peptide as substrate incubated for 1.5 hrs				Citation and Details Article DOI: 10.1016/j.bmc.2021.116437 BindingDB Entry DOI: 10.7270/Q2H70KN7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520270 (CHEMBL4456135) Show SMILES NC(=O)c1ccc(cc1OC1CCCCC1)-c1cccnc1 Show InChI InChI=1S/C18H20N2O2/c19-18(21)16-9-8-13(14-5-4-10-20-12-14)11-17(16)22-15-6-2-1-3-7-15/h4-5,8-12,15H,1-3,6-7H2,(H2,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50520261 (CHEMBL4558635) Show SMILES Cn1ccc(n1)-c1cncc(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C16H14N4O/c1-20-7-6-15(19-20)14-8-13(9-18-10-14)11-2-4-12(5-3-11)16(17)21/h2-10H,1H3,(H2,17,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50520289 (CHEMBL4587472) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1nn[nH]n1 Show InChI InChI=1S/C16H16N6O2/c1-9(2)24-14-6-10(3-4-13(14)15(17)23)11-5-12(8-18-7-11)16-19-21-22-20-16/h3-9H,1-2H3,(H2,17,23)(H,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human))	BDBM50520278 (CHEMBL4569209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cn[nH]c1C Show InChI InChI=1S/C19H20N4O2/c1-11(2)25-18-7-13(4-5-16(18)19(20)24)14-6-15(9-21-8-14)17-10-22-23-12(17)3/h4-11H,1-3H3,(H2,20,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
					More data for this Ligand-Target Pair
Protein kinase C iota type (Homo sapiens (Human))	BDBM50526582 (CHEMBL4471416) Show SMILES Nc1ncc(cc1C(=O)Nc1ccncc1)-c1cccc(c1)N1CCNCC1 Show InChI InChI=1S/C21H22N6O/c22-20-19(21(28)26-17-4-6-23-7-5-17)13-16(14-25-20)15-2-1-3-18(12-15)27-10-8-24-9-11-27/h1-7,12-14,24H,8-11H2,(H2,22,25)(H,23,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
ASTAR Curated by ChEMBL					Assay Description Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFAR...				ACS Med Chem Lett 10: 318-323 (2019) Article DOI: 10.1021/acsmedchemlett.8b00546 BindingDB Entry DOI: 10.7270/Q2348PT0
					More data for this Ligand-Target Pair				3D Structure (crystal)

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