Compile Data Set for Download or QSAR

Found 228 hits with Last Name = 'kogushi' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047595 (1-Butyl-3-{2-[3-(5-isopropyl-4-phenyl-imidazol-1-y...) Show SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-5-6-16-28-27(32)30-24-21(4)12-10-15-23(24)33-18-11-17-31-19-29-25(26(31)20(2)3)22-13-8-7-9-14-22/h7-10,12-15,19-20H,5-6,11,16-18H2,1-4H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047525 (1-{2-Dimethylamino-6-[3-(4-phenyl-piperazin-1-yl)-...) Show SMILES CCCCCNC(=O)Nc1c(OCCCN2CCN(CC2)c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H41N5O2/c1-4-5-9-16-28-27(33)29-26-24(30(2)3)14-10-15-25(26)34-22-11-17-31-18-20-32(21-19-31)23-12-7-6-8-13-23/h6-8,10,12-15H,4-5,9,11,16-22H2,1-3H3,(H2,28,29,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047599 (1-{2-[3-(5-Methyl-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1SC Show InChI InChI=1S/C26H34N4O2S/c1-4-5-9-16-27-26(31)29-25-22(14-10-15-23(25)33-3)32-18-11-17-30-19-28-24(20(30)2)21-12-7-6-8-13-21/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047534 (1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propo...) Show SMILES CC(C)CCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1 Show InChI InChI=1S/C28H38N4O2/c1-20(2)15-16-29-28(33)31-25-22(5)11-9-14-24(25)34-18-10-17-32-19-30-26(27(32)21(3)4)23-12-7-6-8-13-23/h6-9,11-14,19-21H,10,15-18H2,1-5H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047509 (1-{2-Dimethylamino-6-[3-(5-phenyl-tetrazol-2-yl)-p...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2nnc(n2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C24H33N7O2/c1-4-5-9-16-25-24(32)26-22-20(30(2)3)14-10-15-21(22)33-18-11-17-31-28-23(27-29-31)19-12-7-6-8-13-19/h6-8,10,12-15H,4-5,9,11,16-18H2,1-3H3,(H2,25,26,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047495 (1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-p...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C26H35N5O2/c1-4-5-9-16-27-26(32)29-25-23(30(2)3)14-10-15-24(25)33-18-11-17-31-19-22(28-20-31)21-12-7-6-8-13-21/h6-8,10,12-15,19-20H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047585 (1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propo...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1 Show InChI InChI=1S/C28H38N4O2/c1-5-6-10-17-29-28(33)31-25-22(4)13-11-16-24(25)34-19-12-18-32-20-30-26(27(32)21(2)3)23-14-8-7-9-15-23/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047511 (1-{2-Dimethylamino-6-[3-(4-phenyl-[1,2,3]triazol-2...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2ncc(n2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C25H34N6O2/c1-4-5-9-16-26-25(32)28-24-22(30(2)3)14-10-15-23(24)33-18-11-17-31-27-19-21(29-31)20-12-7-6-8-13-20/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,26,28,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047499 (1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047499 (1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047597 (1-{2-Ethyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-...) Show SMILES CCCCCNC(=O)Nc1c(CC)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-4-6-10-17-28-27(32)30-26-22(5-2)15-11-16-24(26)33-19-12-18-31-20-29-25(21(31)3)23-13-8-7-9-14-23/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against Acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate (>, denotes no effect at the concentra...				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047589 (1-{2-[3-(5-Methyl-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1[N+]([O-])=O Show InChI InChI=1S/C25H31N5O4/c1-3-4-8-15-26-25(31)28-24-21(30(32)33)13-9-14-22(24)34-17-10-16-29-18-27-23(19(29)2)20-11-6-5-7-12-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,26,28,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047544 (1-{2-Isopropyl-6-[3-(5-methyl-4-phenyl-imidazol-1-...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1C(C)C Show InChI InChI=1S/C28H38N4O2/c1-5-6-10-17-29-28(33)31-27-24(21(2)3)15-11-16-25(27)34-19-12-18-32-20-30-26(22(32)4)23-13-8-7-9-14-23/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047588 (1-Butyl-3-{2-methyl-6-[3-(4-phenyl-imidazol-1-yl)-...) Show SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1)-c1ccccc1 Show InChI InChI=1S/C24H30N4O2/c1-3-4-14-25-24(29)27-23-19(2)10-8-13-22(23)30-16-9-15-28-17-21(26-18-28)20-11-6-5-7-12-20/h5-8,10-13,17-18H,3-4,9,14-16H2,1-2H3,(H2,25,27,29)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047546 (1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES Cc1cccc(OCCCn2cnc(c2Cl)-c2ccccc2)c1NC(=O)NCC(C)(C)C Show InChI InChI=1S/C25H31ClN4O2/c1-18-10-8-13-20(21(18)29-24(31)27-16-25(2,3)4)32-15-9-14-30-17-28-22(23(30)26)19-11-6-5-7-12-19/h5-8,10-13,17H,9,14-16H2,1-4H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047558 (1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1Cl)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O2/c1-3-4-8-15-27-25(31)29-22-19(2)11-9-14-21(22)32-17-10-16-30-18-28-23(24(30)26)20-12-6-5-7-13-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047539 (1-{2-Methanesulfonyl-6-[3-(5-methyl-4-phenyl-imida...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1S(C)(=O)=O Show InChI InChI=1S/C26H34N4O4S/c1-4-5-9-16-27-26(31)29-25-22(14-10-15-23(25)35(3,32)33)34-18-11-17-30-19-28-24(20(30)2)21-12-7-6-8-13-21/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047587 (1-{2-Methyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C26H34N4O2/c1-4-5-9-16-27-26(31)29-24-20(2)12-10-15-23(24)32-18-11-17-30-19-28-25(21(30)3)22-13-7-6-8-14-22/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047493 (1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-p...) Show SMILES CCCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-4-5-6-10-17-28-27(33)30-26-24(31(2)3)15-11-16-25(26)34-19-12-18-32-20-23(29-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047517 (1-(2-{3-[4-(4-Butyl-phenyl)-imidazol-1-yl]-propoxy...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(CCCC)cc2)cccc1N(C)C Show InChI InChI=1S/C30H43N5O2/c1-5-7-9-19-31-30(36)33-29-27(34(3)4)13-10-14-28(29)37-21-11-20-35-22-26(32-23-35)25-17-15-24(16-18-25)12-8-6-2/h10,13-18,22-23H,5-9,11-12,19-21H2,1-4H3,(H2,31,33,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047582 (3-{3-[3-Methyl-2-(3-pentyl-ureido)-phenoxy]-propyl...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(=O)OCC)-c1ccccc1 Show InChI InChI=1S/C28H36N4O4/c1-4-6-10-17-29-28(34)31-24-21(3)13-11-16-23(24)36-19-12-18-32-20-30-25(22-14-8-7-9-15-22)26(32)27(33)35-5-2/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,29,31,34)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047561 (1-Butyl-3-{2-[3-(5-chloro-4-phenyl-imidazol-1-yl)-...) Show SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1Cl)-c1ccccc1 Show InChI InChI=1S/C24H29ClN4O2/c1-3-4-14-26-24(30)28-21-18(2)10-8-13-20(21)31-16-9-15-29-17-27-22(23(29)25)19-11-6-5-7-12-19/h5-8,10-13,17H,3-4,9,14-16H2,1-2H3,(H2,26,28,30)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047529 (1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(SCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5OS/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047529 (1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(SCCCn2cnc(c2C)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5OS/c1-5-6-10-17-28-27(33)30-26-23(31(3)4)15-11-16-24(26)34-19-12-18-32-20-29-25(21(32)2)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047526 (1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imid...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O3/c1-5-6-7-16-28-27(33)30-26-24(31(2)3)10-8-11-25(26)35-18-9-17-32-19-23(29-20-32)21-12-14-22(34-4)15-13-21/h8,10-15,19-20H,5-7,9,16-18H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047589 (1-{2-[3-(5-Methyl-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1[N+]([O-])=O Show InChI InChI=1S/C25H31N5O4/c1-3-4-8-15-26-25(31)28-24-21(30(32)33)13-9-14-22(24)34-17-10-16-29-18-27-23(19(29)2)20-11-6-5-7-12-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,26,28,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047493 (1-{2-Dimethylamino-6-[3-(4-phenyl-imidazol-1-yl)-p...) Show SMILES CCCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-4-5-6-10-17-28-27(33)30-26-24(31(2)3)15-11-16-25(26)34-19-12-18-32-20-23(29-21-32)22-13-8-7-9-14-22/h7-9,11,13-16,20-21H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047579 (1-{2-Methyl-6-[3-(4-phenyl-5-propyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1CCC)-c1ccccc1 Show InChI InChI=1S/C28H38N4O2/c1-4-6-10-18-29-28(33)31-26-22(3)14-11-17-25(26)34-20-12-19-32-21-30-27(24(32)13-5-2)23-15-8-7-9-16-23/h7-9,11,14-17,21H,4-6,10,12-13,18-20H2,1-3H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047502 (1-{2-Dimethylamino-6-[3-(4-naphthalen-1-yl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2cccc3ccccc23)cccc1N(C)C Show InChI InChI=1S/C30H37N5O2/c1-4-5-8-18-31-30(36)33-29-27(34(2)3)16-10-17-28(29)37-20-11-19-35-21-26(32-22-35)25-15-9-13-23-12-6-7-14-24(23)25/h6-7,9-10,12-17,21-22H,4-5,8,11,18-20H2,1-3H3,(H2,31,33,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047559 (1-(2,2-Dimethyl-propyl)-3-{2-[3-(5-ethyl-4-phenyl-...) Show SMILES CCc1c(ncn1CCCOc1cccc(C)c1NC(=O)NCC(C)(C)C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-6-22-25(21-13-8-7-9-14-21)29-19-31(22)16-11-17-33-23-15-10-12-20(2)24(23)30-26(32)28-18-27(3,4)5/h7-10,12-15,19H,6,11,16-18H2,1-5H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047581 (1-Hexyl-3-{2-methyl-6-[3-(5-methyl-4-phenyl-imidaz...) Show SMILES CCCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-4-5-6-10-17-28-27(32)30-25-21(2)13-11-16-24(25)33-19-12-18-31-20-29-26(22(31)3)23-14-8-7-9-15-23/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047542 (1-{2-Fluoro-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(F)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C25H31FN4O2/c1-3-4-8-15-27-25(31)29-24-21(26)13-9-14-22(24)32-17-10-16-30-18-28-23(19(30)2)20-11-6-5-7-12-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047554 (1-(2-Methyl-6-{3-[4-(4-nitro-phenyl)-imidazol-1-yl...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C25H31N5O4/c1-3-4-5-14-26-25(31)28-24-19(2)8-6-9-23(24)34-16-7-15-29-17-22(27-18-29)20-10-12-21(13-11-20)30(32)33/h6,8-13,17-18H,3-5,7,14-16H2,1-2H3,(H2,26,28,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047592 (1-{2-Methyl-6-[2-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1CSCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C26H34N4OS/c1-4-5-9-15-27-26(31)29-24-20(2)11-10-14-23(24)18-32-17-16-30-19-28-25(21(30)3)22-12-7-6-8-13-22/h6-8,10-14,19H,4-5,9,15-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047544 (1-{2-Isopropyl-6-[3-(5-methyl-4-phenyl-imidazol-1-...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2C)-c2ccccc2)cccc1C(C)C Show InChI InChI=1S/C28H38N4O2/c1-5-6-10-17-29-28(33)31-27-24(21(2)3)15-11-16-25(27)34-19-12-18-32-20-30-26(22(32)4)23-13-8-7-9-14-23/h7-9,11,13-16,20-21H,5-6,10,12,17-19H2,1-4H3,(H2,29,31,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047542 (1-{2-Fluoro-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(F)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C25H31FN4O2/c1-3-4-8-15-27-25(31)29-24-21(26)13-9-14-22(24)32-17-10-16-30-18-28-23(19(30)2)20-11-6-5-7-12-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047548 (1-{2-[3-(5-Ethyl-4-phenyl-imidazol-1-yl)-propoxy]-...) Show SMILES CCc1c(ncn1CCCOc1cccc(C)c1NC(=O)NCCC(C)C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-5-23-26(22-12-7-6-8-13-22)29-19-31(23)17-10-18-33-24-14-9-11-21(4)25(24)30-27(32)28-16-15-20(2)3/h6-9,11-14,19-20H,5,10,15-18H2,1-4H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047520 (1-Cyclohexyl-3-{2-dimethylamino-6-[3-(4-phenyl-imi...) Show SMILES CN(C)c1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NC1CCCCC1 Show InChI InChI=1S/C27H35N5O2/c1-31(2)24-15-9-16-25(26(24)30-27(33)29-22-13-7-4-8-14-22)34-18-10-17-32-19-23(28-20-32)21-11-5-3-6-12-21/h3,5-6,9,11-12,15-16,19-20,22H,4,7-8,10,13-14,17-18H2,1-2H3,(H2,29,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047567 (1-(2,2-Dimethyl-propyl)-3-{2-methyl-6-[3-(4-phenyl...) Show SMILES Cc1cccc(OCCCn2cnc(c2)-c2ccccc2)c1NC(=O)NCC(C)(C)C Show InChI InChI=1S/C25H32N4O2/c1-19-10-8-13-22(23(19)28-24(30)26-17-25(2,3)4)31-15-9-14-29-16-21(27-18-29)20-11-6-5-7-12-20/h5-8,10-13,16,18H,9,14-15,17H2,1-4H3,(H2,26,28,30)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047602 (1-{2-Chloro-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(Cl)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O2/c1-3-4-8-15-27-25(31)29-24-21(26)13-9-14-22(24)32-17-10-16-30-18-28-23(19(30)2)20-11-6-5-7-12-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047541 (1-Butyl-3-{2-methyl-6-[3-(5-methyl-4-phenyl-imidaz...) Show SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C25H32N4O2/c1-4-5-15-26-25(30)28-23-19(2)11-9-14-22(23)31-17-10-16-29-18-27-24(20(29)3)21-12-7-6-8-13-21/h6-9,11-14,18H,4-5,10,15-17H2,1-3H3,(H2,26,28,30)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047550 (1-{2-Methyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1SCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C26H34N4OS/c1-4-5-9-16-27-26(31)29-24-20(2)12-10-15-23(24)32-18-11-17-30-19-28-25(21(30)3)22-13-7-6-8-14-22/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047578 (1-{2-[3-(5-Ethyl-4-phenyl-imidazol-1-yl)-propoxy]-...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1CC)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-4-6-10-17-28-27(32)30-25-21(3)13-11-16-24(25)33-19-12-18-31-20-29-26(23(31)5-2)22-14-8-7-9-15-22/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047597 (1-{2-Ethyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-...) Show SMILES CCCCCNC(=O)Nc1c(CC)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-4-6-10-17-28-27(32)30-26-22(5-2)15-11-16-24(26)33-19-12-18-31-20-29-25(21(31)3)23-13-8-7-9-14-23/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047581 (1-Hexyl-3-{2-methyl-6-[3-(5-methyl-4-phenyl-imidaz...) Show SMILES CCCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C27H36N4O2/c1-4-5-6-10-17-28-27(32)30-25-21(2)13-11-16-24(25)33-19-12-18-31-20-29-26(22(31)3)23-14-8-7-9-15-23/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047558 (1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1Cl)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O2/c1-3-4-8-15-27-25(31)29-22-19(2)11-9-14-21(22)32-17-10-16-30-18-28-23(24(30)26)20-12-6-5-7-13-20/h5-7,9,11-14,18H,3-4,8,10,15-17H2,1-2H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047501 (1-{2-Dimethylamino-6-[3-(4-methyl-5-phenyl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(C)c2-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O2/c1-5-6-10-17-28-27(33)30-25-23(31(3)4)15-11-16-24(25)34-19-12-18-32-20-29-21(2)26(32)22-13-8-7-9-14-22/h7-9,11,13-16,20H,5-6,10,12,17-19H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047550 (1-{2-Methyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...) Show SMILES CCCCCNC(=O)Nc1c(C)cccc1SCCCn1cnc(c1C)-c1ccccc1 Show InChI InChI=1S/C26H34N4OS/c1-4-5-9-16-27-26(31)29-24-20(2)12-10-15-23(24)32-18-11-17-30-19-28-25(21(30)3)22-13-7-6-8-14-22/h6-8,10,12-15,19H,4-5,9,11,16-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047577 (1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...) Show SMILES CC(C)CCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1Cl)-c1ccccc1 Show InChI InChI=1S/C25H31ClN4O2/c1-18(2)13-14-27-25(31)29-22-19(3)9-7-12-21(22)32-16-8-15-30-17-28-23(24(30)26)20-10-5-4-6-11-20/h4-7,9-12,17-18H,8,13-16H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047557 (1-Butyl-3-{2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)-p...) Show SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1CC)-c1ccccc1 Show InChI InChI=1S/C26H34N4O2/c1-4-6-16-27-26(31)29-24-20(3)12-10-15-23(24)32-18-11-17-30-19-28-25(22(30)5-2)21-13-8-7-9-14-21/h7-10,12-15,19H,4-6,11,16-18H2,1-3H3,(H2,27,29,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate				J Med Chem 36: 1641-53 (1993) BindingDB Entry DOI: 10.7270/Q2XP7406
					More data for this Ligand-Target Pair

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