Compile Data Set for Download or QSAR

Found 292 hits with Last Name = 'le huerou' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136465 (US8865726, 96) Show SMILES Fc1ccc(cc1Cl)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136474 (US8865726, 105 | US8865726, 140) Show SMILES Fc1ccc(nc1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136478 (US8865726, 109) Show SMILES Fc1ccc(cc1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136496 (US8865726, 127) Show SMILES Cc1nc(ccc1F)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.790	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136472 (US8865726, 103) Show SMILES Fc1ccc(cc1F)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.870	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136464 (US8865726, 95) Show SMILES Fc1ccc(cc1Cl)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136482 (US8865726, 113) Show SMILES Fc1cccc(c1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136385 (US8865726, 16) Show SMILES CC(C)[C@H]1CN(CCCO)C(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3ncc[nH]3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136431 (US8865726, 62) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)C1CCCCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136501 (US8865726, 132) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1cccc(Cl)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136441 (US8865726, 72) Show SMILES CCC[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136466 (US8865726, 97) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)C1CCCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136487 (US8865726, 118) Show SMILES COc1ccccc1[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136384 (US8865726, 15) Show SMILES CC(C)[C@H]1CN(CCO)C(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3ncc[nH]3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136497 (US8865726, 128) Show SMILES Cc1nc(ccc1F)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136440 (US8865726, 71) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136484 (US8865726, 115) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(Cl)cn1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136375 (US8865726, 6) Show SMILES CC(C)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136449 (US8865726, 80) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@@H](CC2CC2)COC1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136479 (US8865726, 110) Show SMILES Fc1ccc(cc1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136453 (US8865726, 84) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1cccnc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136370 (US8865726, 1) Show SMILES CC(C)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3ncc[nH]3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136498 (US8865726, 129) Show SMILES Cc1cc(ncc1F)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136373 (US8865726, 4) Show SMILES O=C1OC[C@@H](N1c1ccn2ncc(-c3ccc(cc3)-c3ncc[nH]3)c2n1)c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136394 (US8865726, 25) Show SMILES CC(C)[C@H]1CN(CCO)C(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136481 (US8865726, 112) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(cn1)C(F)(F)F |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136483 (US8865726, 114) Show SMILES Fc1ccc(nc1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136389 (US8865726, 20) Show SMILES CC(C)[C@H]1CN(C[C@H](O)CO)C(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3ncc[nH]3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136494 (US8865726, 125) Show SMILES COc1cccc(n1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136425 (US8865726, 56) Show SMILES CC(C)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(Cl)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136456 (US8865726, 87) Show SMILES Cc1cccc(n1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136474 (US8865726, 105 | US8865726, 140) Show SMILES Fc1ccc(nc1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136430 (US8865726, 61) Show SMILES O=C1OC[C@H](C2CCCCC2)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136499 (US8865726, 130) Show SMILES Cc1cc(ncc1F)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136433 (US8865726, 64) Show SMILES O=C1OC[C@@H](N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1)c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136451 (US8865726, 82) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)C1CCOCC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136450 (US8865726, 81) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)C1CC1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136506 (US8865726, 137) Show SMILES Nc1nnc(o1)-c1ccc(cc1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H16FN7O3/c24-16-7-5-14(6-8-16)18-12-33-23(32)31(18)19-9-10-30-20(27-19)17(11-26-30)13-1-3-15(4-2-13)21-28-29-22(25)34-21/h1-11,18H,12H2,(H2,25,29)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136460 (US8865726, 91) Show SMILES Cc1nc(n[nH]1)-c1ccc(cc1)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(F)cc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136395 (US8865726, 26) Show SMILES CC(C)[C@H]1CNC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136374 (US8865726, 5) Show SMILES CC(C)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136503 (US8865726, 134) Show SMILES Fc1ccc(cc1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3cc[nH]n3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136477 (US8865726, 108) Show SMILES Clc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1C(COC1=O)c1ccccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136404 (US8865726, 35) Show SMILES CC(C)[C@H]1CN(CCN2CC3CCC(C2)O3)C(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nc[nH]n3)c2n1 |r,TLB:7:8:11.12:15| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136386 (US8865726, 17) Show SMILES COCCN1C[C@H](C(C)C)N(C1=O)c1ccn2ncc(-c3ccc(cc3)-c3ncc[nH]3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136462 (US8865726, 93) Show SMILES Fc1cc(ccc1-c1nc[nH]n1)-c1cnn2ccc(nc12)N1[C@H]2CCCC[C@H]2OC1=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136421 (US8865726, 52) Show SMILES CC(C)[C@H]1CN(CC2CCNCC2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136380 (US8865726, 11) Show SMILES CC(C)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(cc3)-c3nnc(C)[nH]3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136512 (US8865726, 143) Show SMILES Nc1nnc(o1)-c1ccc(cc1F)-c1cnn2ccc(nc12)N1[C@H](COC1=O)c1ccc(F)cn1 |r| Show InChI InChI=1S/C22H14F2N8O3/c23-12-2-4-16(26-8-12)17-10-34-22(33)32(17)18-5-6-31-19(28-18)14(9-27-31)11-1-3-13(15(24)7-11)20-29-30-21(25)35-20/h1-9,17H,10H2,(H2,25,30)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM136454 (US8865726, 85) Show SMILES Cc1csc(n1)[C@H]1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.40	n/a	n/a	n/a	n/a	7.5	22
Array BioPharma Inc. US Patent					Assay Description The ability of compounds of Formula I to inhibit mTOR was determined in a radioactive filtration assay that measures the transfer of radiolabeled pho...				US Patent US8865726 (2014) BindingDB Entry DOI: 10.7270/Q2V69H93
					More data for this Ligand-Target Pair

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