Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003852 ((4-{2-[(4-Carbamimidoyl-benzoyl)-methyl-amino]-ace...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition of FG binding to alpha IIb beta3 integrin | J Med Chem 39: 3139-47 (1996) Article DOI: 10.1021/jm9509298 BindingDB Entry DOI: 10.7270/Q2GT5M7Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043839 ((E)-6-[2-(4-Fluoro-benzenesulfonylamino)-indan-5-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003874 (CHEMBL108111 | LAMIFIBAN | Ro-44-9883 | {1-[(S)-2-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition of FG binding to alpha IIb beta3 integrin | J Med Chem 39: 3139-47 (1996) Article DOI: 10.1021/jm9509298 BindingDB Entry DOI: 10.7270/Q2GT5M7Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003867 (CHEMBL65267 | Ro-44-3888 | {1-[(S)-2-(4-Carbamimid...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition of FG binding to alpha IIb beta3 integrin | J Med Chem 39: 3139-47 (1996) Article DOI: 10.1021/jm9509298 BindingDB Entry DOI: 10.7270/Q2GT5M7Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043826 (6-{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-phe...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075644 ((E)-6-[3-({[(E)-Benzenesulfonylimino]-tert-butylam...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075630 (6-{3-[1-(1-adamantylamino)-2-cyano-(E)-1-iminometh...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50075643 ((E)-6-[3-(1-tert-Butylamino-2,2-dicyano-vinylamino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075618 (6-{3-[2-cyano-1-cyclopentylamino-(E)-1-iminomethyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075645 (6-{3-[2-cyano-1-cyclohexylamino-(E)-1-iminomethyla...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075637 (6-{3-[2-cyano-1-isopentylamino-(E)-1-iminomethylam...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50404013 (CHEMBL2112677) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti... | Bioorg Med Chem Lett 12: 407-9 (2002) BindingDB Entry DOI: 10.7270/Q21C1W6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003795 (5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars | DrugBank Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075636 ((E)-6-[3-(N'-Benzoyl-N''-cyclopentyl-guanidino)-ph...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075624 (6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043841 ((E)-6-{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075634 ((E)-6-[3-(3-tert-Butyl-ureido)-phenyl]-6-pyridin-3...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043851 ((E)-6-(4-{2-[(4-Chloro-benzenesulfonyl)-ethyl-amin...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043868 ((E)-6-{4-[2-(4-Fluoro-benzenesulfonylamino)-ethyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043856 ((Z)-6-{5-[2-(4-Fluoro-benzenesulfonylamino)-ethyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043841 ((E)-6-{4-[2-(4-Chloro-benzenesulfonylamino)-ethyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043829 ((E)-6-{3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043827 ((E)-6-(4-{2-[(4-Chloro-benzenesulfonyl)-(2-morphol...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003795 (5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars | DrugBank PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003795 (5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars | DrugBank PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043847 (3-((E)-2-{4-[2-(4-Chloro-benzenesulfonylamino)-eth...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043833 ((E)-6-{4-[2-(4-Methoxy-benzenesulfonylamino)-ethyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043858 ((E)-6-[4-(2-Benzenesulfonylamino-ethyl)-phenyl]-6-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075632 (8-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043852 ((E)-6-(4-{2-[Carbamoylmethyl-(4-chloro-benzenesulf...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043845 ((E)-6-[4-(2-Phenylmethanesulfonylamino-ethyl)-phen...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043843 ((E)-6-Pyridin-3-yl-6-{4-[2-(toluene-4-sulfonylamin...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043844 ((E)-6-[4-(4-Chloro-benzenesulfonylamino)-phenyl]-6...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043850 ((E)-6-{4-[2-(Butane-1-sulfonylamino)-ethyl]-phenyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043855 ((E)-6-{4-[2-(3,4-Dimethoxy-benzenesulfonylamino)-e...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075631 (5-[2-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminome...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043838 ((E)-6-{3-[(4-Chloro-benzenesulfonylamino)-methyl]-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043848 ((E)-6-Pyridin-3-yl-6-{4-[2-(4-trifluoromethyl-benz...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075625 (7-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043828 ((E)-6-[3-(4-Chloro-benzenesulfonylamino)-phenyl]-6...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50075641 (6-{3-[2-cyano-1-isobutylamino-(E)-1-iminomethylami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043832 ((E)-6-{4-[(4-Chloro-benzenesulfonylamino)-methyl]-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50043849 ((E)-6-[6-(4-Chloro-benzenesulfonylamino)-5,6,7,8-t...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50043839 ((E)-6-[2-(4-Fluoro-benzenesulfonylamino)-indan-5-y...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr. Karl Thomae GmbH Curated by ChEMBL | Assay Description Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets. | J Med Chem 37: 26-39 (1994) BindingDB Entry DOI: 10.7270/Q2SB44T4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50404013 (CHEMBL2112677) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Tested in vitro binding affinity for displacement of [3H]-M-MPEP from membrane of L(-tk) cells expressing the Metabotropic glutamate receptor 5, acti... | Bioorg Med Chem Lett 12: 407-9 (2002) BindingDB Entry DOI: 10.7270/Q21C1W6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50075623 (6-{3-[1-benzylamino-2-cyano-(E)-1-iminomethylamino...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane A2 receptor (Homo sapiens (Human)) | BDBM50075624 (6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets. | J Med Chem 42: 1235-49 (1999) Article DOI: 10.1021/jm9707941 BindingDB Entry DOI: 10.7270/Q2H41QMS | |||||||||||
More data for this Ligand-Target Pair |
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