Compile Data Set for Download or QSAR

Found 208 hits with Last Name = 'maiocchi' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 1 hr preincubation by fluorometry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 30 mins preincubation by fluorometry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299056 ((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(=O)NO Show InChI InChI=1S/C22H21NO5S/c1-15(22(24)23-25)20-5-3-4-6-21(20)29(26,27)19-13-9-17(10-14-19)16-7-11-18(28-2)12-8-16/h3-15,25H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299052 (CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neutrophil collagenase (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299054 (2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetami...) Show SMILES ONC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H17NO4S/c22-20(21-23)14-17-8-4-5-9-19(17)26(24,25)18-12-10-16(11-13-18)15-6-2-1-3-7-15/h1-13,23H,14H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299058 ((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-p...) Show SMILES CC(C(=O)NO)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H19NO4S/c1-15(21(23)22-24)19-9-5-6-10-20(19)27(25,26)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-15,24H,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299056 ((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(=O)NO Show InChI InChI=1S/C22H21NO5S/c1-15(22(24)23-25)20-5-3-4-6-21(20)29(26,27)19-13-9-17(10-14-19)16-7-11-18(28-2)12-8-16/h3-15,25H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299052 (CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299056 ((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(=O)NO Show InChI InChI=1S/C22H21NO5S/c1-15(22(24)23-25)20-5-3-4-6-21(20)29(26,27)19-13-9-17(10-14-19)16-7-11-18(28-2)12-8-16/h3-15,25H,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50427868 (CHEMBL2326366) Show SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccc(OCCF)cc1 Show InChI InChI=1S/C22H19FO5S/c23-13-14-28-19-9-5-16(6-10-19)17-7-11-20(12-8-17)29(26,27)21-4-2-1-3-18(21)15-22(24)25/h1-12H,13-15H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL					Assay Description Inhibition of MMP-2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay				J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50427868 (CHEMBL2326366) Show SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccc(OCCF)cc1 Show InChI InChI=1S/C22H19FO5S/c23-13-14-28-19-9-5-16(6-10-19)17-7-11-20(12-8-17)29(26,27)21-4-2-1-3-18(21)15-22(24)25/h1-12H,13-15H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL					Assay Description Inhibition of MMP-13 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay				J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299052 (CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299053 (CHEMBL573714 | N-Hydroxy-2-(2-(4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C15H15NO5S/c1-21-12-6-8-13(9-7-12)22(19,20)14-5-3-2-4-11(14)10-15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50299051 (CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1 Show InChI InChI=1S/C21H19NO6S/c1-27-16-6-8-17(9-7-16)28-18-10-12-19(13-11-18)29(25,26)20-5-3-2-4-15(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299054 (2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetami...) Show SMILES ONC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H17NO4S/c22-20(21-23)14-17-8-4-5-9-19(17)26(24,25)18-12-10-16(11-13-18)15-6-2-1-3-7-15/h1-13,23H,14H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50427868 (CHEMBL2326366) Show SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccc(OCCF)cc1 Show InChI InChI=1S/C22H19FO5S/c23-13-14-28-19-9-5-16(6-10-19)17-7-11-20(12-8-17)29(26,27)21-4-2-1-3-18(21)15-22(24)25/h1-12H,13-15H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL					Assay Description Inhibition of MMP-12 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay				J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299055 (CHEMBL573936 | [2-(4'-Methoxy-biphenyl-4-sulfonyl)...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(O)=O Show InChI InChI=1S/C21H18O5S/c1-26-18-10-6-15(7-11-18)16-8-12-19(13-9-16)27(24,25)20-5-3-2-4-17(20)14-21(22)23/h2-13H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Homo sapiens (Human))	BDBM50161330 ((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...) Show SMILES CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50299056 ((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(=O)NO Show InChI InChI=1S/C22H21NO5S/c1-15(22(24)23-25)20-5-3-4-6-21(20)29(26,27)19-13-9-17(10-14-19)16-7-11-18(28-2)12-8-16/h3-15,25H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50427869 (CHEMBL2326365) Show SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccc(NC(=O)CF)cc1 Show InChI InChI=1S/C22H18FNO5S/c23-14-21(25)24-18-9-5-15(6-10-18)16-7-11-19(12-8-16)30(28,29)20-4-2-1-3-17(20)13-22(26)27/h1-12H,13-14H2,(H,24,25)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL					Assay Description Inhibition of MMP-2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay				J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299054 (2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-acetami...) Show SMILES ONC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H17NO4S/c22-20(21-23)14-17-8-4-5-9-19(17)26(24,25)18-12-10-16(11-13-18)15-6-2-1-3-7-15/h1-13,23H,14H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50299056 ((+/-)-N-Hydroxy-2-[2-(4'-methoxy-biphenyl-4-sulfon...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(=O)NO Show InChI InChI=1S/C22H21NO5S/c1-15(22(24)23-25)20-5-3-4-6-21(20)29(26,27)19-13-9-17(10-14-19)16-7-11-18(28-2)12-8-16/h3-15,25H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299058 ((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-p...) Show SMILES CC(C(=O)NO)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H19NO4S/c1-15(21(23)22-24)19-9-5-6-10-20(19)27(25,26)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-15,24H,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299058 ((+/-)-2-[2-(Biphenyl-4-sulfonyl)phenyl]N-hydroxy-p...) Show SMILES CC(C(=O)NO)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H19NO4S/c1-15(21(23)22-24)19-9-5-6-10-20(19)27(25,26)18-13-11-17(12-14-18)16-7-3-2-4-8-16/h2-15,24H,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299055 (CHEMBL573936 | [2-(4'-Methoxy-biphenyl-4-sulfonyl)...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(O)=O Show InChI InChI=1S/C21H18O5S/c1-26-18-10-6-15(7-11-18)16-8-12-19(13-9-16)27(24,25)20-5-3-2-4-17(20)14-21(22)23/h2-13H,14H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50299053 (CHEMBL573714 | N-Hydroxy-2-(2-(4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C15H15NO5S/c1-21-12-6-8-13(9-7-12)22(19,20)14-5-3-2-4-11(14)10-15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50299052 (CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50299053 (CHEMBL573714 | N-Hydroxy-2-(2-(4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C15H15NO5S/c1-21-12-6-8-13(9-7-12)22(19,20)14-5-3-2-4-11(14)10-15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50299055 (CHEMBL573936 | [2-(4'-Methoxy-biphenyl-4-sulfonyl)...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(O)=O Show InChI InChI=1S/C21H18O5S/c1-26-18-10-6-15(7-11-18)16-8-12-19(13-9-16)27(24,25)20-5-3-2-4-17(20)14-21(22)23/h2-13H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50299059 (CHEMBL573934 | N-Hydroxy-2-(4'-methoxybiphenyl-4-y...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO Show InChI InChI=1S/C20H17NO5S/c1-26-16-10-6-14(7-11-16)15-8-12-17(13-9-15)27(24,25)19-5-3-2-4-18(19)20(22)21-23/h2-13,23H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50427868 (CHEMBL2326366) Show SMILES OC(=O)Cc1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccc(OCCF)cc1 Show InChI InChI=1S/C22H19FO5S/c23-13-14-28-19-9-5-16(6-10-19)17-7-11-20(12-8-17)29(26,27)21-4-2-1-3-18(21)15-22(24)25/h1-12H,13-15H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL					Assay Description Inhibition of MMP-9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay				J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50299052 (CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Homo sapiens (Human))	BDBM50299052 (CHEMBL584365 | N-Hydroxy-2-[2-(4'-methoxy-biphenyl...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C21H19NO5S/c1-27-18-10-6-15(7-11-18)16-8-12-19(13-9-16)28(25,26)20-5-3-2-4-17(20)14-21(23)22-24/h2-13,24H,14H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-16 (Homo sapiens (Human))	BDBM50299053 (CHEMBL573714 | N-Hydroxy-2-(2-(4-methoxyphenylsulf...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO Show InChI InChI=1S/C15H15NO5S/c1-21-12-6-8-13(9-7-12)22(19,20)14-5-3-2-4-11(14)10-15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry				J Med Chem 52: 6347-61 (2009) Article DOI: 10.1021/jm900335a BindingDB Entry DOI: 10.7270/Q2HQ3ZZS
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 208 total )  |  Next  |  Last  >>

Jump to: