Compile Data Set for Download or QSAR

Found 515 hits with Last Name = 'manns' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458766 (CHEMBL4212386) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(C(=O)N[C@@H](CC(O)=O)C(O)=O)c(OCC)c1 |r| Show InChI InChI=1S/C30H40N4O11/c1-4-7-8-9-19(22(5-2)34(43)17-35)27(38)31-16-32-29(40)24-13-12-23(45-24)18-10-11-20(25(14-18)44-6-3)28(39)33-21(30(41)42)15-26(36)37/h10-14,17,19,21-22,43H,4-9,15-16H2,1-3H3,(H,31,38)(H,32,40)(H,33,39)(H,36,37)(H,41,42)/t19-,21+,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	0.00680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tolloid-like protein 1 (Homo sapiens)	BDBM50458766 (CHEMBL4212386) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(C(=O)N[C@@H](CC(O)=O)C(O)=O)c(OCC)c1 |r| Show InChI InChI=1S/C30H40N4O11/c1-4-7-8-9-19(22(5-2)34(43)17-35)27(38)31-16-32-29(40)24-13-12-23(45-24)18-10-11-20(25(14-18)44-6-3)28(39)33-21(30(41)42)15-26(36)37/h10-14,17,19,21-22,43H,4-9,15-16H2,1-3H3,(H,31,38)(H,32,40)(H,33,39)(H,36,37)(H,41,42)/t19-,21+,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	0.0310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tolloid-like protein 2 (Homo sapiens)	BDBM50458766 (CHEMBL4212386) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(C(=O)N[C@@H](CC(O)=O)C(O)=O)c(OCC)c1 |r| Show InChI InChI=1S/C30H40N4O11/c1-4-7-8-9-19(22(5-2)34(43)17-35)27(38)31-16-32-29(40)24-13-12-23(45-24)18-10-11-20(25(14-18)44-6-3)28(39)33-21(30(41)42)15-26(36)37/h10-14,17,19,21-22,43H,4-9,15-16H2,1-3H3,(H,31,38)(H,32,40)(H,33,39)(H,36,37)(H,41,42)/t19-,21+,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	0.0390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458771 (CHEMBL4214046) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cc(OCC)cc(c1)P(O)(O)=O |r| Show InChI InChI=1S/C25H36N3O9P/c1-4-7-8-9-20(21(5-2)28(32)16-29)24(30)26-15-27-25(31)23-11-10-22(37-23)17-12-18(36-6-3)14-19(13-17)38(33,34)35/h10-14,16,20-21,32H,4-9,15H2,1-3H3,(H,26,30)(H,27,31)(H2,33,34,35)/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546794 (CHEMBL4777335) Show SMILES CC(C)(C)CC(=O)N[C@@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)C(=O)NC1(CC1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546794 (CHEMBL4777335) Show SMILES CC(C)(C)CC(=O)N[C@@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)C(=O)NC1(CC1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546795 (CHEMBL4777740) Show SMILES O=C(Cc1cccs1)N[C@@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)C(=O)NC1(CC1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546795 (CHEMBL4777740) Show SMILES O=C(Cc1cccs1)N[C@@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)C(=O)NC1(CC1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Tolloid-like protein 1 (Homo sapiens)	BDBM50458771 (CHEMBL4214046) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cc(OCC)cc(c1)P(O)(O)=O |r| Show InChI InChI=1S/C25H36N3O9P/c1-4-7-8-9-20(21(5-2)28(32)16-29)24(30)26-15-27-25(31)23-11-10-22(37-23)17-12-18(36-6-3)14-19(13-17)38(33,34)35/h10-14,16,20-21,32H,4-9,15H2,1-3H3,(H,26,30)(H,27,31)(H2,33,34,35)/t20-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546796 (CHEMBL4761229) Show SMILES O=C(NC1(CC1)C#N)[C@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)Nc1cccnc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546796 (CHEMBL4761229) Show SMILES O=C(NC1(CC1)C#N)[C@H](CS(=O)(=O)N1CCN(CC1)c1ccccn1)Nc1cccnc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Tolloid-like protein 2 (Homo sapiens)	BDBM50458771 (CHEMBL4214046) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cc(OCC)cc(c1)P(O)(O)=O |r| Show InChI InChI=1S/C25H36N3O9P/c1-4-7-8-9-20(21(5-2)28(32)16-29)24(30)26-15-27-25(31)23-11-10-22(37-23)17-12-18(36-6-3)14-19(13-17)38(33,34)35/h10-14,16,20-21,32H,4-9,15H2,1-3H3,(H,26,30)(H,27,31)(H2,33,34,35)/t20-,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546797 (CHEMBL4757049) Show SMILES O=C(NC1(CC1)C#N)[C@@H](Cc1ccccc1)CS(=O)(=O)N1CCN(CC1)c1ccccn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546797 (CHEMBL4757049) Show SMILES O=C(NC1(CC1)C#N)[C@@H](Cc1ccccc1)CS(=O)(=O)N1CCN(CC1)c1ccccn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546800 (CHEMBL4758443) Show SMILES Cc1cc(CC(=O)N[C@@H](CS(=O)(=O)N2CCN(CC2)c2ccccn2)C(=O)NC2(CC2)C#N)on1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	345	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546800 (CHEMBL4758443) Show SMILES Cc1cc(CC(=O)N[C@@H](CS(=O)(=O)N2CCN(CC2)c2ccccn2)C(=O)NC2(CC2)C#N)on1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	345	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546798 (CHEMBL4779026) Show SMILES CNC(=O)CCS(=O)(=O)N1CCN(CC1)c1ccc2nncn2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546798 (CHEMBL4779026) Show SMILES CNC(=O)CCS(=O)(=O)N1CCN(CC1)c1ccc2nncn2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546799 (CHEMBL4755678) Show SMILES O=C(CCS(=O)(=O)N1CCN(CC1)c1ccccn1)NC1(CC1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50546799 (CHEMBL4755678) Show SMILES O=C(CCS(=O)(=O)N1CCN(CC1)c1ccccn1)NC1(CC1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human Cathepsin S expressed in baculovirus infected insect cells using Z-VVR-AMC as substrate preincubated for 15 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00949 BindingDB Entry DOI: 10.7270/Q2NV9NVM
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458766 (CHEMBL4212386) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(C(=O)N[C@@H](CC(O)=O)C(O)=O)c(OCC)c1 |r| Show InChI InChI=1S/C30H40N4O11/c1-4-7-8-9-19(22(5-2)34(43)17-35)27(38)31-16-32-29(40)24-13-12-23(45-24)18-10-11-20(25(14-18)44-6-3)28(39)33-21(30(41)42)15-26(36)37/h10-14,17,19,21-22,43H,4-9,15-16H2,1-3H3,(H,31,38)(H,32,40)(H,33,39)(H,36,37)(H,41,42)/t19-,21+,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458775 (CHEMBL4218415) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cc(OCC)cc(c1)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C30H40N4O11/c1-4-7-8-9-21(23(5-2)34(43)17-35)28(39)31-16-32-29(40)25-11-10-24(45-25)18-12-19(14-20(13-18)44-6-3)27(38)33-22(30(41)42)15-26(36)37/h10-14,17,21-23,43H,4-9,15-16H2,1-3H3,(H,31,39)(H,32,40)(H,33,38)(H,36,37)(H,41,42)/t21-,22+,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of GST-tagged PI4K-alpha (1 to 2044) (unknown origin) using D-myo-phosphatidylinositol as substrate preincubated for 30 mins followed by s...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458774 (CHEMBL4202714) Show SMILES CCCCC[C@H](CN(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C22H27N3O7/c1-2-3-4-5-17(12-25(31)14-26)20(27)23-13-24-21(28)19-11-10-18(32-19)15-6-8-16(9-7-15)22(29)30/h6-11,14,17,31H,2-5,12-13H2,1H3,(H,23,27)(H,24,28)(H,29,30)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458773 (CHEMBL4204567) Show SMILES CCCCC[C@H](CN(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cccc(OCC)c1 |r| Show InChI InChI=1S/C23H31N3O6/c1-3-5-6-8-18(14-26(30)16-27)22(28)24-15-25-23(29)21-12-11-20(32-21)17-9-7-10-19(13-17)31-4-2/h7,9-13,16,18,30H,3-6,8,14-15H2,1-2H3,(H,24,28)(H,25,29)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458771 (CHEMBL4214046) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cc(OCC)cc(c1)P(O)(O)=O |r| Show InChI InChI=1S/C25H36N3O9P/c1-4-7-8-9-20(21(5-2)28(32)16-29)24(30)26-15-27-25(31)23-11-10-22(37-23)17-12-18(36-6-3)14-19(13-17)38(33,34)35/h10-14,16,20-21,32H,4-9,15H2,1-3H3,(H,26,30)(H,27,31)(H2,33,34,35)/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458765 (CHEMBL4205697) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(c(OCC)c1)P(O)(O)=O |r| Show InChI InChI=1S/C25H36N3O9P/c1-4-7-8-9-18(19(5-2)28(32)16-29)24(30)26-15-27-25(31)21-12-11-20(37-21)17-10-13-23(38(33,34)35)22(14-17)36-6-3/h10-14,16,18-19,32H,4-9,15H2,1-3H3,(H,26,30)(H,27,31)(H2,33,34,35)/t18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458764 (CHEMBL4209125) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(C(O)=O)c(OCC)c1 |r| Show InChI InChI=1S/C26H35N3O8/c1-4-7-8-9-18(20(5-2)29(35)16-30)24(31)27-15-28-25(32)22-13-12-21(37-22)17-10-11-19(26(33)34)23(14-17)36-6-3/h10-14,16,18,20,35H,4-9,15H2,1-3H3,(H,27,31)(H,28,32)(H,33,34)/t18-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458763 (CHEMBL4202848) Show SMILES CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cc(OCC)cc(c1)C(O)=O |r| Show InChI InChI=1S/C26H35N3O8/c1-4-7-8-9-20(21(5-2)29(35)16-30)24(31)27-15-28-25(32)23-11-10-22(37-23)17-12-18(26(33)34)14-19(13-17)36-6-3/h10-14,16,20-21,35H,4-9,15H2,1-3H3,(H,27,31)(H,28,32)(H,33,34)/t20-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Short transient receptor potential channel 6 (Homo sapiens (Human))	BDBM50439218 (CHEMBL2418809) Show SMILES CC1CCCN(C1C)C(=O)c1nc(Nc2cc3OCOc3cc2F)sc1Cl Show InChI InChI=1S/C18H19ClFN3O3S/c1-9-4-3-5-23(10(9)2)17(24)15-16(19)27-18(22-15)21-12-7-14-13(6-11(12)20)25-8-26-14/h6-7,9-10H,3-5,8H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay				Bioorg Med Chem Lett 23: 4979-84 (2013) Article DOI: 10.1016/j.bmcl.2013.06.047 BindingDB Entry DOI: 10.7270/Q2319X9H
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294706 (4-((2-chlorobenzyl)(3-methyl-1-(1-methyl-1H-tetraz...) Show SMILES CC(C)CC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nnnn1C Show InChI InChI=1S/C21H22Cl2N6/c1-14(2)10-20(21-25-26-27-28(21)3)29(13-16-6-4-5-7-18(16)22)17-9-8-15(12-24)19(23)11-17/h4-9,11,14,20H,10,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50296010 (2-isobutyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-...) Show SMILES CC(C)Cc1cc(ccc1C(O)=O)-c1c[nH]c2ncc(cc12)-c1ccccc1 Show InChI InChI=1S/C24H22N2O2/c1-15(2)10-18-11-17(8-9-20(18)24(27)28)22-14-26-23-21(22)12-19(13-25-23)16-6-4-3-5-7-16/h3-9,11-15H,10H2,1-2H3,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of SGK1 by fluorescence polarization assay				Bioorg Med Chem Lett 19: 4441-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.051 BindingDB Entry DOI: 10.7270/Q2WQ03VC
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50458758 (CHEMBL4207907) Show SMILES CCCCC[C@H](CN(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C22H27N3O7/c1-2-3-4-6-17(12-25(31)14-26)20(27)23-13-24-21(28)19-10-9-18(32-19)15-7-5-8-16(11-15)22(29)30/h5,7-11,14,17,31H,2-4,6,12-13H2,1H3,(H,23,27)(H,24,28)(H,29,30)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...				ACS Med Chem Lett 9: 736-740 (2018) Article DOI: 10.1021/acsmedchemlett.8b00173 BindingDB Entry DOI: 10.7270/Q2X35127
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298210 ((S)-2-chloro-4-((2,5-dichlorobenzyl)(1-ethyl-5-oxo...) Show SMILES CCN1C[C@H](CC1=O)N(Cc1cc(Cl)ccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H18Cl3N3O/c1-2-25-12-17(9-20(25)27)26(11-14-7-15(21)4-6-18(14)22)16-5-3-13(10-24)19(23)8-16/h3-8,17H,2,9,11-12H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298207 ((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropyl-5-oxo...) Show SMILES CC(C)N1C[C@H](CC1=O)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H21Cl2N3O/c1-14(2)25-13-18(10-21(25)27)26(12-16-5-3-4-6-19(16)22)17-8-7-15(11-24)20(23)9-17/h3-9,14,18H,10,12-13H2,1-2H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298208 ((S)-2-chloro-4-((2-chloro-5-fluorobenzyl)(1-ethyl-...) Show SMILES CCN1C[C@H](CC1=O)N(Cc1cc(F)ccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H18Cl2FN3O/c1-2-25-12-17(9-20(25)27)26(11-14-7-15(23)4-6-18(14)21)16-5-3-13(10-24)19(22)8-16/h3-8,17H,2,9,11-12H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294715 (4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...) Show SMILES CCCC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nncn1C Show InChI InChI=1S/C21H21Cl2N5/c1-3-6-20(21-26-25-14-27(21)2)28(13-16-7-4-5-8-18(16)22)17-10-9-15(12-24)19(23)11-17/h4-5,7-11,14,20H,3,6,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294702 (4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)e...) Show SMILES CC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nnnn1C Show InChI InChI=1S/C18H16Cl2N6/c1-12(18-22-23-24-25(18)2)26(11-14-5-3-4-6-16(14)19)15-8-7-13(10-21)17(20)9-15/h3-9,12H,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294703 (4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...) Show SMILES CC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nncn1C Show InChI InChI=1S/C19H17Cl2N5/c1-13(19-24-23-12-25(19)2)26(11-15-5-3-4-6-17(15)20)16-8-7-14(10-22)18(21)9-16/h3-9,12-13H,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50296011 (2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin...) Show SMILES OC(=O)c1ccc(cc1C1CCCC1)-c1c[nH]c2ncc(cc12)-c1ccccc1 Show InChI InChI=1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of SGK1 by fluorescence polarization assay				Bioorg Med Chem Lett 19: 4441-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.051 BindingDB Entry DOI: 10.7270/Q2WQ03VC
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294705 (4-((2-chlorobenzyl)(1-(1-methyl-1H-tetrazol-5-yl)p...) Show SMILES CCC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nnnn1C Show InChI InChI=1S/C19H18Cl2N6/c1-3-18(19-23-24-25-26(19)2)27(12-14-6-4-5-7-16(14)20)15-9-8-13(11-22)17(21)10-15/h4-10,18H,3,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294696 (4-((2-chlorobenzyl)(1-(2-methylthiazol-4-yl)ethyl)...) Show SMILES CC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1csc(C)n1 Show InChI InChI=1S/C20H17Cl2N3S/c1-13(20-12-26-14(2)24-20)25(11-16-5-3-4-6-18(16)21)17-8-7-15(10-23)19(22)9-17/h3-9,12-13H,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298219 ((R)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298209 ((S)-2-chloro-4-((1-ethyl-5-oxopyrrolidin-3-yl)(2-m...) Show SMILES CCN1C[C@H](CC1=O)N(Cc1ccccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H22ClN3O/c1-3-24-14-19(11-21(24)26)25(13-17-7-5-4-6-15(17)2)18-9-8-16(12-23)20(22)10-18/h4-10,19H,3,11,13-14H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 19: 4664-8 (2009) Article DOI: 10.1016/j.bmcl.2009.06.081 BindingDB Entry DOI: 10.7270/Q25H7G9T
					More data for this Ligand-Target Pair
Short transient receptor potential channel 6 (Homo sapiens (Human))	BDBM50439217 (CHEMBL2418811) Show SMILES C[C@H]1CCCN([C@H]1C)C(=O)c1nc(Nc2ccc(Cl)cc2F)sc1C |r| Show InChI InChI=1S/C18H21ClFN3OS/c1-10-5-4-8-23(11(10)2)17(24)16-12(3)25-18(22-16)21-15-7-6-13(19)9-14(15)20/h6-7,9-11H,4-5,8H2,1-3H3,(H,21,22)/t10-,11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay				Bioorg Med Chem Lett 23: 4979-84 (2013) Article DOI: 10.1016/j.bmcl.2013.06.047 BindingDB Entry DOI: 10.7270/Q2319X9H
					More data for this Ligand-Target Pair
Short transient receptor potential channel 6 (Homo sapiens (Human))	BDBM50439220 (CHEMBL2418807) Show SMILES CC1CCCN(C1C)C(=O)c1csc(Nc2ccc3OCOc3c2)n1 Show InChI InChI=1S/C18H21N3O3S/c1-11-4-3-7-21(12(11)2)17(22)14-9-25-18(20-14)19-13-5-6-15-16(8-13)24-10-23-15/h5-6,8-9,11-12H,3-4,7,10H2,1-2H3,(H,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay				Bioorg Med Chem Lett 23: 4979-84 (2013) Article DOI: 10.1016/j.bmcl.2013.06.047 BindingDB Entry DOI: 10.7270/Q2319X9H
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294707 (4-((2-chlorobenzyl)(1-(1-ethyl-1H-tetrazol-5-yl)et...) Show SMILES CCn1nnnc1C(C)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 Show InChI InChI=1S/C19H18Cl2N6/c1-3-27-19(23-24-25-27)13(2)26(12-15-6-4-5-7-17(15)20)16-9-8-14(11-22)18(21)10-16/h4-10,13H,3,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294710 (2-chloro-4-(isobutyl(3-methyl-1-(1-methyl-1H-tetra...) Show SMILES CC(C)CC(N(CC(C)C)c1ccc(C#N)c(Cl)c1)c1nnnn1C Show InChI InChI=1S/C18H25ClN6/c1-12(2)8-17(18-21-22-23-24(18)5)25(11-13(3)4)15-7-6-14(10-20)16(19)9-15/h6-7,9,12-13,17H,8,11H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294712 ((S)-2-chloro-4-((cyclobutylmethyl)(3-methyl-1-(1-m...) Show SMILES CC(C)C[C@H](N(CC1CCC1)c1ccc(C#N)c(Cl)c1)c1nnnn1C |r| Show InChI InChI=1S/C19H25ClN6/c1-13(2)9-18(19-22-23-24-25(19)3)26(12-14-5-4-6-14)16-8-7-15(11-21)17(20)10-16/h7-8,10,13-14,18H,4-6,9,12H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50294714 (4-((2-chlorobenzyl)(1-(4-methyl-4H-1,2,4-triazol-3...) Show SMILES CCC(N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1)c1nncn1C Show InChI InChI=1S/C20H19Cl2N5/c1-3-19(20-25-24-13-26(20)2)27(12-15-6-4-5-7-17(15)21)16-9-8-14(11-23)18(22)10-16/h4-10,13,19H,3,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor ligand binding domain by fluorimetric assay				Bioorg Med Chem Lett 19: 2637-41 (2009) Article DOI: 10.1016/j.bmcl.2009.03.146 BindingDB Entry DOI: 10.7270/Q2FX79GM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50296009 (2-ethyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...) Show SMILES CCc1cc(ccc1C(O)=O)-c1c[nH]c2ncc(cc12)-c1ccccc1 Show InChI InChI=1S/C22H18N2O2/c1-2-14-10-16(8-9-18(14)22(25)26)20-13-24-21-19(20)11-17(12-23-21)15-6-4-3-5-7-15/h3-13H,2H2,1H3,(H,23,24)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of SGK1 by fluorescence polarization assay				Bioorg Med Chem Lett 19: 4441-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.051 BindingDB Entry DOI: 10.7270/Q2WQ03VC
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 515 total )  |  Next  |  Last  >>

Jump to: