Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM197 ((2S)-N-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S)-3-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50064201 (1N-benzyl-2N-[1-benzyl-4-(2-benzylcarbamoyl-3-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50064202 (1N-benzyl-2N-[1-benzyl-4-(2-benzylcarbamoylcyclopr...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50064199 (1N-benzyl-2N-[1-benzyl-4-(3-benzylcarbamoyl-2,2-di...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50064203 (1N-benzyl-2N-[1-benzyl-4-(2-benzylcarbamoyl-3-meth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50064198 (1N-{1-benzyl-4-[2,2-dimethyl-3-methyl(2-pyridylmet...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM586099 (BDBM50064200 | TL-3) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
Frederick Biomedical Supercomputing Center Curated by ChEMBL | Assay Description Inhibitory activity of the compound was measured against wild-type HIV-1 protease | J Med Chem 41: 1581-97 (1998) Article DOI: 10.1021/jm980033d BindingDB Entry DOI: 10.7270/Q27S7MWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079440 (CHEMBL103214 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079444 (CHEMBL317887 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079443 (CHEMBL431829 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079442 (CHEMBL105553 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079446 (CHEMBL58763 | Gly-Arg-Gly-Asp-Ser-Pro-Lys) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079445 (CHEMBL103089 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079440 (CHEMBL103214 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50079441 (CHEMBL321332 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of Vitronectin receptor (alpha V beta 3) binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079446 (CHEMBL58763 | Gly-Arg-Gly-Asp-Ser-Pro-Lys) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079444 (CHEMBL317887 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079443 (CHEMBL431829 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079445 (CHEMBL103089 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079441 (CHEMBL321332 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50079442 (CHEMBL105553 | [(2R,5R,8R,11S)-5-Benzyl-11-(3-guan...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Inhibition of alpha IIb beta3 integrin binding to fibrinogen | J Med Chem 42: 3033-40 (1999) Article DOI: 10.1021/jm970832g BindingDB Entry DOI: 10.7270/Q2CN733T | |||||||||||
More data for this Ligand-Target Pair |