Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 113 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 152 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 281 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079715 (CHEMBL64237 | Tetradecanethioic acid (2,6-diisopro...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 554 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 619 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 838 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from HepG2 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 926 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from U937 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 4.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from HepG2 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 5.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from U937 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from U937 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
More data for this Ligand-Target Pair |