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Compile Data Set for Download or QSAR

Found 159 hits with Last Name = 'mcburney' and Initial = 'rn'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50344821
PNG
(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)
Show SMILES NC1=N[C@H](O)[C@H]2[C@H]3O[C@]4(O)O[C@@H]([C@@H](O)[C@@]2(N1)[C@@H]4O)[C@]3(O)CO |r,t:1,TLB:13:12:16:6.7.5,18:11:16:6.7.5,18:6:16:11.10.12,19:18:7:16.14.5,20:18:7:16.14.5,THB:12:11:7:16.14.5,3:5:16:11.10.12|
Show InChI InChI=1S/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2-,3-,4-,5+,6-,7+,9+,10-,11+/m1/s1
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n/an/a 4n/an/an/an/an/an/a



Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010747
PNG
(CHEMBL543201 | CHEMBL78777 | N,N'-Bis-(3-ethyl-phe...)
Show SMILES CCc1cccc(NC(N)=Nc2cccc(CC)c2)c1 |w:10.10|
Show InChI InChI=1S/C17H21N3/c1-3-13-7-5-9-15(11-13)19-17(18)20-16-10-6-8-14(4-2)12-16/h5-12H,3-4H2,1-2H3,(H3,18,19,20)
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n/an/a 8n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010758
PNG
(CHEMBL312600 | N,N'-Bis-(2-iodo-phenyl)-guanidine)
Show SMILES NC(Nc1ccccc1I)=Nc1ccccc1I |w:10.11|
Show InChI InChI=1S/C13H11I2N3/c14-9-5-1-3-7-11(9)17-13(16)18-12-8-4-2-6-10(12)15/h1-8H,(H3,16,17,18)
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n/an/a 13n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010760
PNG
(CHEMBL310170 | N,N'-Bis-(2-ethyl-phenyl)-guanidine)
Show SMILES CCc1ccccc1NC(N)=Nc1ccccc1CC |w:11.12|
Show InChI InChI=1S/C17H21N3/c1-3-13-9-5-7-11-15(13)19-17(18)20-16-12-8-6-10-14(16)4-2/h5-12H,3-4H2,1-2H3,(H3,18,19,20)
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n/an/a 14n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043978
PNG
(CHEMBL315051 | N,N'-Di-indan-4-yl-guanidine)
Show SMILES NC(Nc1cccc2CCCc12)=Nc1cccc2CCCc12 |w:12.14|
Show InChI InChI=1S/C19H21N3/c20-19(21-17-11-3-7-13-5-1-9-15(13)17)22-18-12-4-8-14-6-2-10-16(14)18/h3-4,7-8,11-12H,1-2,5-6,9-10H2,(H3,20,21,22)
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n/an/a 29n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM81982
PNG
(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11|
Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
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n/an/a 31n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010784
PNG
(CHEMBL81070 | N,N'-Bis-(4-bromo-phenyl)-guanidine)
Show SMILES NC(Nc1ccc(Br)cc1)=Nc1ccc(Br)cc1 |w:10.11|
Show InChI InChI=1S/C13H11Br2N3/c14-9-1-5-11(6-2-9)17-13(16)18-12-7-3-10(15)4-8-12/h1-8H,(H3,16,17,18)
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n/an/a 33n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043950
PNG
(CHEMBL90508 | N-(2-Iodo-phenyl)-N'-naphthalen-1-yl...)
Show SMILES NC(Nc1ccccc1I)=Nc1cccc2ccccc12 |w:10.11|
Show InChI InChI=1S/C17H14IN3/c18-14-9-3-4-10-16(14)21-17(19)20-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H3,19,20,21)
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n/an/a 40n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010739
PNG
(CHEMBL79437 | N,N'-Bis-(3-propyl-phenyl)-guanidine)
Show SMILES CCCc1cccc(NC(N)=Nc2cccc(CCC)c2)c1 |w:11.11|
Show InChI InChI=1S/C19H25N3/c1-3-7-15-9-5-11-17(13-15)21-19(20)22-18-12-6-10-16(14-18)8-4-2/h5-6,9-14H,3-4,7-8H2,1-2H3,(H3,20,21,22)
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n/an/a 42n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010791
PNG
(CHEMBL309603 | N,N'-Di-m-tolyl-guanidine)
Show SMILES Cc1cccc(NC(N)=Nc2cccc(C)c2)c1 |w:9.9|
Show InChI InChI=1S/C15H17N3/c1-11-5-3-7-13(9-11)17-15(16)18-14-8-4-6-12(2)10-14/h3-10H,1-2H3,(H3,16,17,18)
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n/an/a 43n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043968
PNG
(CHEMBL91713 | N-(3-Ethyl-phenyl)-N'-naphthalen-1-y...)
Show SMILES CCc1cccc(NC(N)=Nc2cccc3ccccc23)c1 |w:10.10|
Show InChI InChI=1S/C19H19N3/c1-2-14-7-5-10-16(13-14)21-19(20)22-18-12-6-9-15-8-3-4-11-17(15)18/h3-13H,2H2,1H3,(H3,20,21,22)
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n/an/a 54n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010806
PNG
(CHEMBL78306 | N,N'-Bis-(5,6,7,8-tetrahydro-naphtha...)
Show SMILES NC(Nc1cccc2CCCCc12)=Nc1cccc2CCCCc12 |w:13.15|
Show InChI InChI=1S/C21H25N3/c22-21(23-19-13-5-9-15-7-1-3-11-17(15)19)24-20-14-6-10-16-8-2-4-12-18(16)20/h5-6,9-10,13-14H,1-4,7-8,11-12H2,(H3,22,23,24)
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n/an/a 59n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043963
PNG
(CHEMBL88660 | N-(3-Ethyl-phenyl)-4-phenyl-piperidi...)
Show SMILES CCc1cccc(c1)N=C(N)N1CCC(CC1)c1ccccc1 |w:8.8|
Show InChI InChI=1S/C20H25N3/c1-2-16-7-6-10-19(15-16)22-20(21)23-13-11-18(12-14-23)17-8-4-3-5-9-17/h3-10,15,18H,2,11-14H2,1H3,(H2,21,22)
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n/an/a 60n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066062
PNG
(1,3-Bis-(4-sec-butyl-phenyl)-imidazolidin-2-yliden...)
Show SMILES CCC(C)c1ccc(cc1)N1CCN(C1=N)c1ccc(cc1)C(C)CC
Show InChI InChI=1S/C23H31N3/c1-5-17(3)19-7-11-21(12-8-19)25-15-16-26(23(25)24)22-13-9-20(10-14-22)18(4)6-2/h7-14,17-18,24H,5-6,15-16H2,1-4H3
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n/an/a 60n/an/an/an/an/an/a



Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066059
PNG
(1,3-Bis-(4-sec-butyl-phenyl)-tetrahydro-pyrimidin-...)
Show SMILES CCC(C)c1ccc(cc1)N1CCCN(C1=N)c1ccc(cc1)C(C)CC
Show InChI InChI=1S/C24H33N3/c1-5-18(3)20-8-12-22(13-9-20)26-16-7-17-27(24(26)25)23-14-10-21(11-15-23)19(4)6-2/h8-15,18-19,25H,5-7,16-17H2,1-4H3
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n/an/a 60n/an/an/an/an/an/a



Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043955
PNG
(CHEMBL88932 | N-Naphthalen-1-yl-N'-m-tolyl-guanidi...)
Show SMILES Cc1cccc(NC(N)=Nc2cccc3ccccc23)c1 |w:9.9|
Show InChI InChI=1S/C18H17N3/c1-13-6-4-9-15(12-13)20-18(19)21-17-11-5-8-14-7-2-3-10-16(14)17/h2-12H,1H3,(H3,19,20,21)
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n/an/a 75n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043977
PNG
(CHEMBL543434 | CHEMBL91628 | N,N'-Bis-(3-ethyl-phe...)
Show SMILES CCc1cccc(c1)N=C(N)N(C)c1cccc(CC)c1 |w:8.8|
Show InChI InChI=1S/C18H23N3/c1-4-14-8-6-10-16(12-14)20-18(19)21(3)17-11-7-9-15(5-2)13-17/h6-13H,4-5H2,1-3H3,(H2,19,20)
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n/an/a 82n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010755
PNG
(CHEMBL280243 | N,N'-Bis-(2-isopropyl-phenyl)-guani...)
Show SMILES CC(C)c1ccccc1NC(N)=Nc1ccccc1C(C)C |w:12.13|
Show InChI InChI=1S/C19H25N3/c1-13(2)15-9-5-7-11-17(15)21-19(20)22-18-12-8-6-10-16(18)14(3)4/h5-14H,1-4H3,(H3,20,21,22)
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n/an/a 88n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043947
PNG
(CHEMBL89344 | N-(2-Isopropyl-phenyl)-N'-naphthalen...)
Show SMILES CC(C)c1ccccc1N=C(N)Nc1cccc2ccccc12 |w:9.9|
Show InChI InChI=1S/C20H21N3/c1-14(2)16-10-5-6-12-18(16)22-20(21)23-19-13-7-9-15-8-3-4-11-17(15)19/h3-14H,1-2H3,(H3,21,22,23)
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n/an/a 91n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043970
PNG
(CHEMBL91791 | N,N'-Di-naphthalen-2-yl-guanidine)
Show SMILES NC(Nc1ccc2ccccc2c1)=Nc1ccc2ccccc2c1 |w:13.15|
Show InChI InChI=1S/C21H17N3/c22-21(23-19-11-9-15-5-1-3-7-17(15)13-19)24-20-12-10-16-6-2-4-8-18(16)14-20/h1-14H,(H3,22,23,24)
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n/an/a 92n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010789
PNG
(CHEMBL82078 | N,N'-Bis-(3-isopropyl-phenyl)-guanid...)
Show SMILES CC(C)c1cccc(NC(N)=Nc2cccc(c2)C(C)C)c1 |w:11.11|
Show InChI InChI=1S/C19H25N3/c1-13(2)15-7-5-9-17(11-15)21-19(20)22-18-10-6-8-16(12-18)14(3)4/h5-14H,1-4H3,(H3,20,21,22)
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n/an/a 96n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010797
PNG
(CHEMBL81678 | N,N'-Bis-(3-iodo-phenyl)-guanidine)
Show SMILES NC(Nc1cccc(I)c1)=Nc1cccc(I)c1 |w:10.11|
Show InChI InChI=1S/C13H11I2N3/c14-9-3-1-5-11(7-9)17-13(16)18-12-6-2-4-10(15)8-12/h1-8H,(H3,16,17,18)
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Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043951
PNG
(CHEMBL90975 | N-Benzyl-N'-naphthalen-1-yl-guanidin...)
Show SMILES NC(NCc1ccccc1)=Nc1cccc2ccccc12 |w:10.11|
Show InChI InChI=1S/C18H17N3/c19-18(20-13-14-7-2-1-3-8-14)21-17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2,(H3,19,20,21)
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n/an/a 140n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010810
PNG
(CHEMBL79509 | N,N'-Di-naphthalen-1-yl-guanidine)
Show SMILES NC(Nc1cccc2ccccc12)=Nc1cccc2ccccc12 |w:13.15|
Show InChI InChI=1S/C21H17N3/c22-21(23-19-13-5-9-15-7-1-3-11-17(15)19)24-20-14-6-10-16-8-2-4-12-18(16)20/h1-14H,(H3,22,23,24)
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n/an/a 165n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043953
PNG
(CHEMBL430455 | N-Indan-2-yl-N'-naphthalen-1-yl-gua...)
Show SMILES NC(NC1Cc2ccccc2C1)=Nc1cccc2ccccc12 |w:12.14|
Show InChI InChI=1S/C20H19N3/c21-20(22-17-12-15-7-1-2-8-16(15)13-17)23-19-11-5-9-14-6-3-4-10-18(14)19/h1-11,17H,12-13H2,(H3,21,22,23)
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n/an/a 240n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010754
PNG
(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)
Show SMILES CC(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)C)cc1 |w:10.10|
Show InChI InChI=1S/C19H25N3/c1-13(2)15-5-9-17(10-6-15)21-19(20)22-18-11-7-16(8-12-18)14(3)4/h5-14H,1-4H3,(H3,20,21,22)
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n/an/a 242n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010736
PNG
(CHEMBL78083 | N,N'-Bis-(4-ethyl-phenyl)-guanidine)
Show SMILES CCc1ccc(NC(N)=Nc2ccc(CC)cc2)cc1 |w:9.9|
Show InChI InChI=1S/C17H21N3/c1-3-13-5-9-15(10-6-13)19-17(18)20-16-11-7-14(4-2)8-12-16/h5-12H,3-4H2,1-2H3,(H3,18,19,20)
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n/an/a 245n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043964
PNG
(CHEMBL330551 | N-Methyl-N,N'-di-m-tolyl-guanidine)
Show SMILES CN(C(N)=Nc1cccc(C)c1)c1cccc(C)c1 |w:4.4|
Show InChI InChI=1S/C16H19N3/c1-12-6-4-8-14(10-12)18-16(17)19(3)15-9-5-7-13(2)11-15/h4-11H,1-3H3,(H2,17,18)
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n/an/a 247n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066066
PNG
((S)-1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidi...)
Show SMILES CN(C1CCN(C[C@H](O)COc2ccc(F)c(F)c2)CC1)c1nc2ccccc2s1
Show InChI InChI=1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1
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n/an/a 260n/an/an/an/an/an/a



Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043946
PNG
(CHEMBL314423 | N-(3-Ethyl-phenyl)-2,3-dihydro-indo...)
Show SMILES CCc1cccc(c1)N=C(N)N1CCc2ccccc12 |w:8.8|
Show InChI InChI=1S/C17H19N3/c1-2-13-6-5-8-15(12-13)19-17(18)20-11-10-14-7-3-4-9-16(14)20/h3-9,12H,2,10-11H2,1H3,(H2,18,19)
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Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043980
PNG
(CHEMBL431214 | N-Naphthalen-1-yl-4-phenyl-piperidi...)
Show SMILES NC(=Nc1cccc2ccccc12)N1CCC(CC1)c1ccccc1 |w:2.2|
Show InChI InChI=1S/C22H23N3/c23-22(24-21-12-6-10-19-9-4-5-11-20(19)21)25-15-13-18(14-16-25)17-7-2-1-3-8-17/h1-12,18H,13-16H2,(H2,23,24)
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n/an/a 343n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043945
PNG
(CHEMBL91222 | N,N'-Bis-(3-methoxy-phenyl)-guanidin...)
Show SMILES COc1cccc(NC(N)=Nc2cccc(OC)c2)c1 |w:10.10|
Show InChI InChI=1S/C15H17N3O2/c1-19-13-7-3-5-11(9-13)17-15(16)18-12-6-4-8-14(10-12)20-2/h3-10H,1-2H3,(H3,16,17,18)
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n/an/a 351n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010786
PNG
(CHEMBL78411 | N,N'-Bis-(2-tert-butyl-phenyl)-guani...)
Show SMILES CC(C)(C)c1ccccc1NC(N)=Nc1ccccc1C(C)(C)C |w:13.14|
Show InChI InChI=1S/C21H29N3/c1-20(2,3)15-11-7-9-13-17(15)23-19(22)24-18-14-10-8-12-16(18)21(4,5)6/h7-14H,1-6H3,(H3,22,23,24)
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n/an/a 356n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010769
PNG
(CHEMBL556117 | CHEMBL77675 | N,N'-Diphenyl-guanidi...)
Show SMILES NC(Nc1ccccc1)=Nc1ccccc1 |w:9.10|
Show InChI InChI=1S/C13H13N3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H,(H3,14,15,16)
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Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066067
PNG
(2-(4-tert-Butyl-phenyl)-6-isopropyl-3,4-dihydro-2H...)
Show SMILES CC(C)c1ccc2N(C(CCc2c1)c1ccc(cc1)C(C)(C)C)C(N)=N
Show InChI InChI=1S/C23H31N3/c1-15(2)17-8-12-21-18(14-17)9-13-20(26(21)22(24)25)16-6-10-19(11-7-16)23(3,4)5/h6-8,10-12,14-15,20H,9,13H2,1-5H3,(H3,24,25)
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Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50010743
PNG
(N,N'-Di-p-tolyl-guanidine)
Show SMILES Cc1ccc(NC(N)=Nc2ccc(C)cc2)cc1 |w:8.8|
Show InChI InChI=1S/C15H17N3/c1-11-3-7-13(8-4-11)17-15(16)18-14-9-5-12(2)6-10-14/h3-10H,1-2H3,(H3,16,17,18)
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n/an/a 535n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))		BDBM50107034
PNG
(CHEMBL108347 | N-(4-Butoxy-benzoyl)-N'-(4-phenyl-b...)
Show SMILES CCCCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:16.17|
Show InChI InChI=1S/C22H29N3O2/c1-2-3-17-27-20-14-12-19(13-15-20)21(26)25-22(23)24-16-8-7-11-18-9-5-4-6-10-18/h4-6,9-10,12-15H,2-3,7-8,11,16-17H2,1H3,(H3,23,24,25,26)
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n/an/a 560n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066069
PNG
(CHEMBL103284 | N-(4-tert-Butyl-benzyl)-N-(4-sec-bu...)
Show SMILES CCC(C)c1ccc(cc1)N(Cc1ccc(cc1)C(C)(C)C)C(N)=N
Show InChI InChI=1S/C22H31N3/c1-6-16(2)18-9-13-20(14-10-18)25(21(23)24)15-17-7-11-19(12-8-17)22(3,4)5/h7-14,16H,6,15H2,1-5H3,(H3,23,24)
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Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50107034
PNG
(CHEMBL108347 | N-(4-Butoxy-benzoyl)-N'-(4-phenyl-b...)
Show SMILES CCCCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:16.17|
Show InChI InChI=1S/C22H29N3O2/c1-2-3-17-27-20-14-12-19(13-15-20)21(26)25-22(23)24-16-8-7-11-18-9-5-4-6-10-18/h4-6,9-10,12-15H,2-3,7-8,11,16-17H2,1H3,(H3,23,24,25,26)
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CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50107029
PNG
(CHEMBL108727 | N-(4-Ethoxy-benzoyl)-N'-(4-phenyl-b...)
Show SMILES CCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:14.15|
Show InChI InChI=1S/C20H25N3O2/c1-2-25-18-13-11-17(12-14-18)19(24)23-20(21)22-15-7-6-10-16-8-4-3-5-9-16/h3-5,8-9,11-14H,2,6-7,10,15H2,1H3,(H3,21,22,23,24)
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n/an/a 760n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066052
PNG
((3-sec-Butyl-phenyl)-[1-(4-sec-butyl-phenyl)-imida...)
Show SMILES CCC(C)c1ccc(cc1)N1CCNC1=Nc1cccc(c1)C(C)CC |w:15.17|
Show InChI InChI=1S/C23H31N3/c1-5-17(3)19-10-12-22(13-11-19)26-15-14-24-23(26)25-21-9-7-8-20(16-21)18(4)6-2/h7-13,16-18H,5-6,14-15H2,1-4H3,(H,24,25)
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Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066057
PNG
(CHEMBL110909 | CHEMBL320199 | N,N'-Bis-(4-sec-buty...)
Show SMILES CCC(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)CC)cc1 |w:11.11|
Show InChI InChI=1S/C21H29N3/c1-5-15(3)17-7-11-19(12-8-17)23-21(22)24-20-13-9-18(10-14-20)16(4)6-2/h7-16H,5-6H2,1-4H3,(H3,22,23,24)
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Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50107043
PNG
(CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...)
Show SMILES COc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:13.14|
Show InChI InChI=1S/C19H23N3O2/c1-24-17-12-10-16(11-13-17)18(23)22-19(20)21-14-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)
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n/an/a 820n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50107032
PNG
(CHEMBL110572 | N-(Naphthalene-1-carbonyl)-N'-(4-ph...)
Show SMILES NC(NC(=O)c1cccc2ccccc12)=NCCCCc1ccccc1 |w:15.17|
Show InChI InChI=1S/C22H23N3O/c23-22(24-16-7-6-11-17-9-2-1-3-10-17)25-21(26)20-15-8-13-18-12-4-5-14-19(18)20/h1-5,8-10,12-15H,6-7,11,16H2,(H3,23,24,25,26)
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n/an/a 860n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043960
PNG
(CHEMBL328986 | N'-(3-Ethyl-phenyl)-N-methyl-N-naph...)
Show SMILES CCc1cccc(c1)N=C(N)N(C)c1cccc2ccccc12 |w:8.8|
Show InChI InChI=1S/C20H21N3/c1-3-15-8-6-11-17(14-15)22-20(21)23(2)19-13-7-10-16-9-4-5-12-18(16)19/h4-14H,3H2,1-2H3,(H2,21,22)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Rattus norvegicus)		BDBM50066060
PNG
(CHEMBL545504 | N,N'-Bis-(4-sec-butyl-phenyl)-N,N'-...)
Show SMILES CCC(C)c1ccc(cc1)N(C)C(=N)N(C)c1ccc(cc1)C(C)CC
Show InChI InChI=1S/C23H33N3/c1-7-17(3)19-9-13-21(14-10-19)25(5)23(24)26(6)22-15-11-20(12-16-22)18(4)8-2/h9-18,24H,7-8H2,1-6H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



Cambridge NeuroScience Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)

J Med Chem 41: 3048-61 (1998)


Article DOI: 10.1021/jm980124a
BindingDB Entry DOI: 10.7270/Q2R49RF5
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))		BDBM50043954
PNG
(CHEMBL91145 | N-Naphthalen-1-yl-piperidine-1-carbo...)
Show SMILES NC(=Nc1cccc2ccccc12)N1CCCCC1 |w:2.2|
Show InChI InChI=1S/C16H19N3/c17-16(19-11-4-1-5-12-19)18-15-10-6-8-13-7-2-3-9-14(13)15/h2-3,6-10H,1,4-5,11-12H2,(H2,17,18)
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n/an/a 1.07E+3n/an/an/an/an/an/a



Cambridge NeuroScience, Inc.

Curated by ChEMBL


Assay Description
Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membrane

J Med Chem 37: 260-7 (1994)


BindingDB Entry DOI: 10.7270/Q2HX1BRZ
More data for this
Ligand-Target Pair
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))		BDBM50107029
PNG
(CHEMBL108727 | N-(4-Ethoxy-benzoyl)-N'-(4-phenyl-b...)
Show SMILES CCOc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:14.15|
Show InChI InChI=1S/C20H25N3O2/c1-2-25-18-13-11-17(12-14-18)19(24)23-20(21)22-15-7-6-10-16-8-4-3-5-9-16/h3-5,8-9,11-14H,2,6-7,10,15H2,1H3,(H3,21,22,23,24)
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n/an/a 1.10E+3n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50107031
PNG
(CHEMBL108728 | N-(4-Methyl-benzoyl)-N'-(4-phenyl-b...)
Show SMILES Cc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1 |w:12.13|
Show InChI InChI=1S/C19H23N3O/c1-15-10-12-17(13-11-15)18(23)22-19(20)21-14-6-5-9-16-7-3-2-4-8-16/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)
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n/an/a 1.14E+3n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50107030
PNG
(CHEMBL106459 | N-(2-Methyl-benzoyl)-N'-(4-phenyl-b...)
Show SMILES Cc1ccccc1C(=O)NC(N)=NCCCCc1ccccc1 |w:12.13|
Show InChI InChI=1S/C19H23N3O/c1-15-9-5-6-13-17(15)18(23)22-19(20)21-14-8-7-12-16-10-3-2-4-11-16/h2-6,9-11,13H,7-8,12,14H2,1H3,(H3,20,21,22,23)
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n/an/a 1.20E+3n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel

Bioorg Med Chem Lett 11: 3151-5 (2001)


BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
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