Compile Data Set for Download or QSAR

Found 175 hits with Last Name = 'mcfarlane' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50302220 (7-((1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-...) Show SMILES Fc1ccc2[nH]c3CCC(CN4CCC(COc5cccc6[nH]c(=O)oc56)CC4)Cc3c2c1 Show InChI InChI=1S/C26H28FN3O3/c27-18-5-7-22-20(13-18)19-12-17(4-6-21(19)28-22)14-30-10-8-16(9-11-30)15-32-24-3-1-2-23-25(24)33-26(31)29-23/h1-3,5,7,13,16-17,28H,4,6,8-12,14-15H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217902 (3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...) Show SMILES ClC1=NC2SC=CN2C1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |c:5,t:1| Show InChI InChI=1S/C17H18ClN5O2S2/c18-14-16(22-7-8-26-17(22)21-14)27(24,25)13-10-23(11-3-1-5-19-9-11)15-12(13)4-2-6-20-15/h2,4,6-8,10-11,16-17,19H,1,3,5,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217922 (3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)C1N2C=CSC2N=C1Cl |c:25,30| Show InChI InChI=1S/C19H22ClN5O2S2/c1-2-23-8-4-5-13(11-23)25-12-15(14-6-3-7-21-17(14)25)29(26,27)18-16(20)22-19-24(18)9-10-28-19/h3,6-7,9-10,12-13,18-19H,2,4-5,8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217909 (3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)C1N2C=CSC2N=C1Cl |c:23,28| Show InChI InChI=1S/C17H18ClN5O2S2/c1-21-6-4-11(9-21)23-10-13(12-3-2-5-19-15(12)23)27(24,25)16-14(18)20-17-22(16)7-8-26-17/h2-3,5,7-8,10-11,16-17H,4,6,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217891 (3-(3-bromo-benzenesulfonyl)-1-(1-methyl-pyrrolidin...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1 |w:4.6| Show InChI InChI=1S/C18H18BrN3O2S/c1-21-9-7-14(11-21)22-12-17(16-6-3-8-20-18(16)22)25(23,24)15-5-2-4-13(19)10-15/h2-6,8,10,12,14H,7,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217904 (3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-y...) Show SMILES Clc1ccc(CS(=O)(=O)c2cn(C3CCNC3)c3ncccc23)s1 |w:12.11| Show InChI InChI=1S/C16H16ClN3O2S2/c17-15-4-3-12(23-15)10-24(21,22)14-9-20(11-5-7-18-8-11)16-13(14)2-1-6-19-16/h1-4,6,9,11,18H,5,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217900 (3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-p...) Show SMILES ClC1=NC2SC=CN2C1S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |c:5,t:1| Show InChI InChI=1S/C16H16ClN5O2S2/c17-13-15(21-6-7-25-16(21)20-13)26(23,24)12-9-22(10-3-5-18-8-10)14-11(12)2-1-4-19-14/h1-2,4,6-7,9-10,15-16,18H,3,5,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50302225 ((1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl...) Show SMILES CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217883 (3-[(5-chlorothien-2-yl)sulfonyl]-1-piperidin-3-yl-...) Show SMILES Clc1ccc(s1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:12.12| Show InChI InChI=1S/C16H16ClN3O2S2/c17-14-5-6-15(23-14)24(21,22)13-10-20(11-3-1-7-18-9-11)16-12(13)4-2-8-19-16/h2,4-6,8,10-11,18H,1,3,7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217916 (3-[(3-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...) Show SMILES Clc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18ClN3O2S/c19-13-4-1-6-15(10-13)25(23,24)17-12-22(14-5-2-8-20-11-14)18-16(17)7-3-9-21-18/h1,3-4,6-7,9-10,12,14,20H,2,5,8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217920 (3-(3-bromo-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hpy...) Show SMILES Brc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16BrN3O2S/c18-12-3-1-4-14(9-12)24(22,23)16-11-21(13-6-8-19-10-13)17-15(16)5-2-7-20-17/h1-5,7,9,11,13,19H,6,8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217893 (1-pyrrolidin-3-yl-3-(3-trifluoromethyl-benzenesulf...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:16.16| Show InChI InChI=1S/C18H16F3N3O2S/c19-18(20,21)12-3-1-4-14(9-12)27(25,26)16-11-24(13-6-8-22-10-13)17-15(16)5-2-7-23-17/h1-5,7,9,11,13,22H,6,8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217925 (3-(3-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:4.6| Show InChI InChI=1S/C18H18FN3O2S/c1-21-9-7-14(11-21)22-12-17(16-6-3-8-20-18(16)22)25(23,24)15-5-2-4-13(19)10-15/h2-6,8,10,12,14H,7,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217928 (3-(6-chloro-imidazo[2,1-b]thiazole-5-sulfonyl)-1-(...) Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)C1N2C=CSC2N=C1Cl |c:24,29| Show InChI InChI=1S/C18H20ClN5O2S2/c1-2-22-7-5-12(10-22)24-11-14(13-4-3-6-20-16(13)24)28(25,26)17-15(19)21-18-23(17)8-9-27-18/h3-4,6,8-9,11-12,17-18H,2,5,7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217924 (3-(3-chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:4.6| Show InChI InChI=1S/C18H18ClN3O2S/c1-21-9-7-14(11-21)22-12-17(16-6-3-8-20-18(16)22)25(23,24)15-5-2-4-13(19)10-15/h2-6,8,10,12,14H,7,9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217880 (3-(3-chloro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...) Show SMILES Clc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16ClN3O2S/c18-12-3-1-4-14(9-12)24(22,23)16-11-21(13-6-8-19-10-13)17-15(16)5-2-7-20-17/h1-5,7,9,11,13,19H,6,8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217913 (3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...) Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)C1N2C=CSC2N=C1Cl |c:26,31| Show InChI InChI=1S/C20H24ClN5O2S2/c1-13(2)24-8-4-5-14(11-24)26-12-16(15-6-3-7-22-18(15)26)30(27,28)19-17(21)23-20-25(19)9-10-29-20/h3,6-7,9-10,12-14,19-20H,4-5,8,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217890 (3-[(5-chlorothien-2-yl)sulfonyl]-1-(1-methylpiperi...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:5.7| Show InChI InChI=1S/C17H18ClN3O2S2/c1-20-9-3-4-12(10-20)21-11-14(13-5-2-8-19-17(13)21)25(22,23)16-7-6-15(18)24-16/h2,5-8,11-12H,3-4,9-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50302213 ((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...) Show SMILES Fc1ccc2[nH]c3CCC(CNC[C@H]4COc5c6CC(=O)Nc6ccc5O4)Cc3c2c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-14-2-4-20-17(8-14)16-7-13(1-3-19(16)27-20)10-26-11-15-12-30-24-18-9-23(29)28-21(18)5-6-22(24)31-15/h2,4-6,8,13,15,26-27H,1,3,7,9-12H2,(H,28,29)/t13?,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at 5-HT2A receptor				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217889 (3-[(2-fluorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...) Show SMILES Fc1ccccc1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18FN3O2S/c19-15-7-1-2-8-16(15)25(23,24)17-12-22(13-5-3-9-20-11-13)18-14(17)6-4-10-21-18/h1-2,4,6-8,10,12-13,20H,3,5,9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50302213 ((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...) Show SMILES Fc1ccc2[nH]c3CCC(CNC[C@H]4COc5c6CC(=O)Nc6ccc5O4)Cc3c2c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-14-2-4-20-17(8-14)16-7-13(1-3-19(16)27-20)10-26-11-15-12-30-24-18-9-23(29)28-21(18)5-6-22(24)31-15/h2,4-6,8,13,15,26-27H,1,3,7,9-12H2,(H,28,29)/t13?,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at 5-HT2A receptor				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217927 (3-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfon...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)C1N2C=CSC2N=C1Cl |c:24,29| Show InChI InChI=1S/C18H20ClN5O2S2/c1-22-7-3-4-12(10-22)24-11-14(13-5-2-6-20-16(13)24)28(25,26)17-15(19)21-18-23(17)8-9-27-18/h2,5-6,8-9,11-12,17-18H,3-4,7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217918 (3-(2-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...) Show SMILES Fc1ccccc1S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16FN3O2S/c18-14-5-1-2-6-15(14)24(22,23)16-11-21(12-7-9-19-10-12)17-13(16)4-3-8-20-17/h1-6,8,11-12,19H,7,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217903 (3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-(1-methy...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(c1)C(F)(F)F |w:5.7| Show InChI InChI=1S/C20H20F3N3O2S/c1-25-10-4-6-15(12-25)26-13-18(17-8-3-9-24-19(17)26)29(27,28)16-7-2-5-14(11-16)20(21,22)23/h2-3,5,7-9,11,13,15H,4,6,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217881 (3-(2-Chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1Cl |w:4.6| Show InChI InChI=1S/C18H18ClN3O2S/c1-21-10-8-13(11-21)22-12-17(14-5-4-9-20-18(14)22)25(23,24)16-7-3-2-6-15(16)19/h2-7,9,12-13H,8,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217884 (3-[(3-fluorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18FN3O2S/c19-13-4-1-6-15(10-13)25(23,24)17-12-22(14-5-2-8-20-11-14)18-16(17)7-3-9-21-18/h1,3-4,6-7,9-10,12,14,20H,2,5,8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217906 (3-benzenesulfonyl-1-(1-methyl-pyrrolidin-3-yl)-1Hp...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1 |w:4.6| Show InChI InChI=1S/C18H19N3O2S/c1-20-11-9-14(12-20)21-13-17(16-8-5-10-19-18(16)21)24(22,23)15-6-3-2-4-7-15/h2-8,10,13-14H,9,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217926 (3-(3-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16FN3O2S/c18-12-3-1-4-14(9-12)24(22,23)16-11-21(13-6-8-19-10-13)17-15(16)5-2-7-20-17/h1-5,7,9,11,13,19H,6,8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50302218 (7-(1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...) Show SMILES Fc1ccc2[nH]c3CCC(CN4CCC(CC4)Oc4cccc5[nH]c(=O)oc45)Cc3c2c1 Show InChI InChI=1S/C25H26FN3O3/c26-16-5-7-21-19(13-16)18-12-15(4-6-20(18)27-21)14-29-10-8-17(9-11-29)31-23-3-1-2-22-24(23)32-25(30)28-22/h1-3,5,7,13,15,17,27H,4,6,8-12,14H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from D2 receptor				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50302213 ((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...) Show SMILES Fc1ccc2[nH]c3CCC(CNC[C@H]4COc5c6CC(=O)Nc6ccc5O4)Cc3c2c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-14-2-4-20-17(8-14)16-7-13(1-3-19(16)27-20)10-26-11-15-12-30-24-18-9-23(29)28-21(18)5-6-22(24)31-15/h2,4-6,8,13,15,26-27H,1,3,7,9-12H2,(H,28,29)/t13?,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from D2 receptor				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50302213 ((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...) Show SMILES Fc1ccc2[nH]c3CCC(CNC[C@H]4COc5c6CC(=O)Nc6ccc5O4)Cc3c2c1 |r| Show InChI InChI=1S/C24H24FN3O3/c25-14-2-4-20-17(8-14)16-7-13(1-3-19(16)27-20)10-26-11-15-12-30-24-18-9-23(29)28-21(18)5-6-22(24)31-15/h2,4-6,8,13,15,26-27H,1,3,7,9-12H2,(H,28,29)/t13?,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from D2 receptor				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217901 (1-(1-ethylpiperidin-3-yl)-3-[(5-chlorothien-2-yl)-...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:6.8| Show InChI InChI=1S/C18H20ClN3O2S2/c1-2-21-10-4-5-13(11-21)22-12-15(14-6-3-9-20-18(14)22)26(23,24)17-8-7-16(19)25-17/h3,6-9,12-13H,2,4-5,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217914 (3-(3-chloro-benzenesulfonyl)-1-(1-ethyl-pyrrolidin...) Show SMILES CCN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H20ClN3O2S/c1-2-22-10-8-15(12-22)23-13-18(17-7-4-9-21-19(17)23)26(24,25)16-6-3-5-14(20)11-16/h3-7,9,11,13,15H,2,8,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217896 (3-[(3-fluorophenyl)sulfonyl]-1-(1-isopropylpiperid...) Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:7.9| Show InChI InChI=1S/C21H24FN3O2S/c1-15(2)24-11-5-7-17(13-24)25-14-20(19-9-4-10-23-21(19)25)28(26,27)18-8-3-6-16(22)12-18/h3-4,6,8-10,12,14-15,17H,5,7,11,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217923 (1-(1-ethylpiperidin-3-yl)-3-(phenylsulfonyl)-1Hpyr...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1 |w:6.8| Show InChI InChI=1S/C20H23N3O2S/c1-2-22-13-7-8-16(14-22)23-15-19(18-11-6-12-21-20(18)23)26(24,25)17-9-4-3-5-10-17/h3-6,9-12,15-16H,2,7-8,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217887 (3-[(2-chlorophenyl)sulfonyl]-1-piperidin-3-yl-1Hpy...) Show SMILES Clc1ccccc1S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18ClN3O2S/c19-15-7-1-2-8-16(15)25(23,24)17-12-22(13-5-3-9-20-11-13)18-14(17)6-4-10-21-18/h1-2,4,6-8,10,12-13,20H,3,5,9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217899 (3-[(3-bromophenyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...) Show SMILES Brc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C18H18BrN3O2S/c19-13-4-1-6-15(10-13)25(23,24)17-12-22(14-5-2-8-20-11-14)18-16(17)7-3-9-21-18/h1,3-4,6-7,9-10,12,14,20H,2,5,8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217892 (3-[(3,5-dichlorophenyl)sulfonyl]-1-(1-methylpiperi...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 |w:5.7| Show InChI InChI=1S/C19H19Cl2N3O2S/c1-23-7-3-4-15(11-23)24-12-18(17-5-2-6-22-19(17)24)27(25,26)16-9-13(20)8-14(21)10-16/h2,5-6,8-10,12,15H,3-4,7,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217907 (3-(4-chloro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)cc1 |w:4.6| Show InChI InChI=1S/C18H18ClN3O2S/c1-21-10-8-14(11-21)22-12-17(16-3-2-9-20-18(16)22)25(23,24)15-6-4-13(19)5-7-15/h2-7,9,12,14H,8,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217930 (3-(4-bromo-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hpy...) Show SMILES Brc1ccc(cc1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16BrN3O2S/c18-12-3-5-14(6-4-12)24(22,23)16-11-21(13-7-9-19-10-13)17-15(16)2-1-8-20-17/h1-6,8,11,13,19H,7,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217895 (1-(1-ethylpiperidin-3-yl)-3-[(3-fluorophenyl)sulfo...) Show SMILES CCN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:6.8| Show InChI InChI=1S/C20H22FN3O2S/c1-2-23-11-5-7-16(13-23)24-14-19(18-9-4-10-22-20(18)24)27(25,26)17-8-3-6-15(21)12-17/h3-4,6,8-10,12,14,16H,2,5,7,11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217885 (3-{[3-(trifluoromethyl)phenyl]sulfonyl}-1-piperidi...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ncccc12 |w:16.16| Show InChI InChI=1S/C19H18F3N3O2S/c20-19(21,22)13-4-1-6-15(10-13)28(26,27)17-12-25(14-5-2-8-23-11-14)18-16(17)7-3-9-24-18/h1,3-4,6-7,9-10,12,14,23H,2,5,8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217898 (3-[(3-fluorophenyl)sulfonyl]-1-(1-methylpiperidin-...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 |w:5.7| Show InChI InChI=1S/C19H20FN3O2S/c1-22-10-4-6-15(12-22)23-13-18(17-8-3-9-21-19(17)23)26(24,25)16-7-2-5-14(20)11-16/h2-3,5,7-9,11,13,15H,4,6,10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217888 (3-(phenylsulfonyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...) Show SMILES O=S(=O)(c1cn(C2CCCNC2)c2ncccc12)c1ccccc1 |w:6.5| Show InChI InChI=1S/C18H19N3O2S/c22-24(23,15-7-2-1-3-8-15)17-13-21(14-6-4-10-19-12-14)18-16(17)9-5-11-20-18/h1-3,5,7-9,11,13-14,19H,4,6,10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217905 (3-(4-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(F)cc1 |w:4.6| Show InChI InChI=1S/C18H18FN3O2S/c1-21-10-8-14(11-21)22-12-17(16-3-2-9-20-18(16)22)25(23,24)15-6-4-13(19)5-7-15/h2-7,9,12,14H,8,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217915 (3-(4-chloro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...) Show SMILES Clc1ccc(cc1)S(=O)(=O)c1cn(C2CCNC2)c2ncccc12 |w:13.13| Show InChI InChI=1S/C17H16ClN3O2S/c18-12-3-5-14(6-4-12)24(22,23)16-11-21(13-7-9-19-10-13)17-15(16)2-1-8-20-17/h1-6,8,11,13,19H,7,9-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217911 (3-(2-fluoro-benzenesulfonyl)-1-(1-methyl-pyrrolidi...) Show SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1F |w:4.6| Show InChI InChI=1S/C18H18FN3O2S/c1-21-10-8-13(11-21)22-12-17(14-5-4-9-20-18(14)22)25(23,24)16-7-3-2-6-15(16)19/h2-7,9,12-13H,8,10-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217931 (8-(1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine-3-s...) Show SMILES O=S(=O)(c1cn(C2CCNC2)c2ncccc12)c1cccc2cccnc12 |w:6.5| Show InChI InChI=1S/C20H18N4O2S/c25-27(26,17-7-1-4-14-5-2-9-22-19(14)17)18-13-24(15-8-11-21-12-15)20-16(18)6-3-10-23-20/h1-7,9-10,13,15,21H,8,11-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50302212 ((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...) Show SMILES Fc1ccc2[nH]c3CC(CCCNC[C@H]4COc5c6CC(=O)Nc6ccc5O4)CCc3c2c1 |r| Show InChI InChI=1S/C26H28FN3O3/c27-16-4-6-21-19(11-16)18-5-3-15(10-23(18)29-21)2-1-9-28-13-17-14-32-26-20-12-25(31)30-22(20)7-8-24(26)33-17/h4,6-8,11,15,17,28-29H,1-3,5,9-10,12-14H2,(H,30,31)/t15?,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at 5-HT2A receptor				Bioorg Med Chem Lett 19: 5552-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.050 BindingDB Entry DOI: 10.7270/Q2Z89DCC
					More data for this Ligand-Target Pair

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