Compile Data Set for Download or QSAR

Found 180 hits with Last Name = 'nisenbaum' and Initial = 'es'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50379862 (CHEMBL2011870) Show SMILES COc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C16H18N2O2S/c1-9-8-13(9)15(19)17-16-10(2)14(18-21-16)11-4-6-12(20-3)7-5-11/h4-7,9,13H,8H2,1-3H3,(H,17,19)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379867 (CHEMBL2011877) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(Br)cc1 |r| Show InChI InChI=1S/C15H15BrN2OS/c1-8-7-12(8)14(19)17-15-9(2)13(18-20-15)10-3-5-11(16)6-4-10/h3-6,8,12H,7H2,1-2H3,(H,17,19)/t8-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379866 (CHEMBL2011874) Show SMILES COc1ccc(cc1F)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C16H17FN2O2S/c1-8-6-11(8)15(20)18-16-9(2)14(19-22-16)10-4-5-13(21-3)12(17)7-10/h4-5,7-8,11H,6H2,1-3H3,(H,18,20)/t8-,11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379861 (CHEMBL2011876) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H15ClN2OS/c1-8-7-12(8)14(19)17-15-9(2)13(18-20-15)10-3-5-11(16)6-4-10/h3-6,8,12H,7H2,1-2H3,(H,17,19)/t8-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379865 (CHEMBL2011873) Show SMILES CCOc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C17H20N2O2S/c1-4-21-13-7-5-12(6-8-13)15-11(3)17(22-19-15)18-16(20)14-9-10(14)2/h5-8,10,14H,4,9H2,1-3H3,(H,18,20)/t10-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379862 (CHEMBL2011870) Show SMILES COc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C16H18N2O2S/c1-9-8-13(9)15(19)17-16-10(2)14(18-21-16)11-4-6-12(20-3)7-5-11/h4-7,9,13H,8H2,1-3H3,(H,17,19)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379862 (CHEMBL2011870) Show SMILES COc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C16H18N2O2S/c1-9-8-13(9)15(19)17-16-10(2)14(18-21-16)11-4-6-12(20-3)7-5-11/h4-7,9,13H,8H2,1-3H3,(H,17,19)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379868 (CHEMBL2011878) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C15H14Cl2N2OS/c1-7-5-10(7)14(20)18-15-8(2)13(19-21-15)9-3-4-11(16)12(17)6-9/h3-4,6-7,10H,5H2,1-2H3,(H,18,20)/t7-,10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379864 (CHEMBL2011872) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccccc1 |r| Show InChI InChI=1S/C15H16N2OS/c1-9-8-12(9)14(18)16-15-10(2)13(17-19-15)11-6-4-3-5-7-11/h3-7,9,12H,8H2,1-2H3,(H,16,18)/t9-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379869 (CHEMBL2011879) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(cc1)C(C)(F)F |r| Show InChI InChI=1S/C17H18F2N2OS/c1-9-8-13(9)15(22)20-16-10(2)14(21-23-16)11-4-6-12(7-5-11)17(3,18)19/h4-7,9,13H,8H2,1-3H3,(H,20,22)/t9-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379865 (CHEMBL2011873) Show SMILES CCOc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C17H20N2O2S/c1-4-21-13-7-5-12(6-8-13)15-11(3)17(22-19-15)18-16(20)14-9-10(14)2/h5-8,10,14H,4,9H2,1-3H3,(H,18,20)/t10-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379860 (CHEMBL2011875) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C15H15FN2OS/c1-8-7-12(8)14(19)17-15-9(2)13(18-20-15)10-3-5-11(16)6-4-10/h3-6,8,12H,7H2,1-2H3,(H,17,19)/t8-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379863 (CHEMBL2011871) Show SMILES COc1ccc(cc1)-c1nsc(NC(=O)[C@H]2C[C@@H]2C)c1C |r| Show InChI InChI=1S/C16H18N2O2S/c1-9-8-13(9)15(19)17-16-10(2)14(18-21-16)11-4-6-12(20-3)7-5-11/h4-7,9,13H,8H2,1-3H3,(H,17,19)/t9-,13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50379870 (CHEMBL2011880) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C15H16N2O2S/c1-8-7-12(8)14(19)16-15-9(2)13(17-20-15)10-3-5-11(18)6-4-10/h3-6,8,12,18H,7H2,1-2H3,(H,16,19)/t8-,12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379862 (CHEMBL2011870) Show SMILES COc1ccc(cc1)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C16H18N2O2S/c1-9-8-13(9)15(19)17-16-10(2)14(18-21-16)11-4-6-12(20-3)7-5-11/h4-7,9,13H,8H2,1-3H3,(H,17,19)/t9-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379866 (CHEMBL2011874) Show SMILES COc1ccc(cc1F)-c1nsc(NC(=O)[C@@H]2C[C@H]2C)c1C |r| Show InChI InChI=1S/C16H17FN2O2S/c1-8-6-11(8)15(20)18-16-9(2)14(19-22-16)10-4-5-13(21-3)12(17)7-10/h4-5,7-8,11H,6H2,1-3H3,(H,18,20)/t8-,11-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379867 (CHEMBL2011877) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(Br)cc1 |r| Show InChI InChI=1S/C15H15BrN2OS/c1-8-7-12(8)14(19)17-15-9(2)13(18-20-15)10-3-5-11(16)6-4-10/h3-6,8,12H,7H2,1-2H3,(H,17,19)/t8-,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379861 (CHEMBL2011876) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H15ClN2OS/c1-8-7-12(8)14(19)17-15-9(2)13(18-20-15)10-3-5-11(16)6-4-10/h3-6,8,12H,7H2,1-2H3,(H,17,19)/t8-,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379868 (CHEMBL2011878) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C15H14Cl2N2OS/c1-7-5-10(7)14(20)18-15-8(2)13(19-21-15)9-3-4-11(16)12(17)6-9/h3-4,6-7,10H,5H2,1-2H3,(H,18,20)/t7-,10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379860 (CHEMBL2011875) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C15H15FN2OS/c1-8-7-12(8)14(19)17-15-9(2)13(18-20-15)10-3-5-11(16)6-4-10/h3-6,8,12H,7H2,1-2H3,(H,17,19)/t8-,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379869 (CHEMBL2011879) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(cc1)C(C)(F)F |r| Show InChI InChI=1S/C17H18F2N2OS/c1-9-8-13(9)15(22)20-16-10(2)14(21-23-16)11-4-6-12(7-5-11)17(3,18)19/h4-7,9,13H,8H2,1-3H3,(H,20,22)/t9-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379870 (CHEMBL2011880) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C15H16N2O2S/c1-8-7-12(8)14(19)16-15-9(2)13(17-20-15)10-3-5-11(18)6-4-10/h3-6,8,12,18H,7H2,1-2H3,(H,16,19)/t8-,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50379864 (CHEMBL2011872) Show SMILES C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccccc1 |r| Show InChI InChI=1S/C15H16N2OS/c1-9-8-12(9)14(18)16-15-10(2)13(17-19-15)11-6-4-3-5-7-11/h3-7,9,12H,8H2,1-2H3,(H,16,18)/t9-,12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5				Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192214 (3-(4-tert-butylphenyl)-4-cyano-5-(ethylthio)thioph...) Show SMILES CCSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H19NO2S2/c1-5-22-17-13(10-19)14(15(23-17)16(20)21)11-6-8-12(9-7-11)18(2,3)4/h6-9H,5H2,1-4H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50094024 ((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...) Show SMILES CC(C)S(=O)(=O)NCC(C)c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H22N2O2S/c1-14(2)24(22,23)21-13-15(3)17-8-10-19(11-9-17)18-6-4-16(12-20)5-7-18/h4-11,14-15,21H,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192215 (3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiop...) Show SMILES CCCSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H21NO2S2/c1-5-10-23-18-14(11-20)15(16(24-18)17(21)22)12-6-8-13(9-7-12)19(2,3)4/h6-9H,5,10H2,1-4H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192216 (3-(4-tert-butylphenyl)-4-cyano-5-ethylthiophene-2-...) Show SMILES CCc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H19NO2S/c1-5-14-13(10-19)15(16(22-14)17(20)21)11-6-8-12(9-7-11)18(2,3)4/h6-9H,5H2,1-4H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192215 (3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiop...) Show SMILES CCCSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H21NO2S2/c1-5-10-23-18-14(11-20)15(16(24-18)17(21)22)12-6-8-13(9-7-12)19(2,3)4/h6-9H,5,10H2,1-4H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192217 (3-(4-tert-butylphenyl)-4-cyano-5-(pyrrolidin-1-yl)...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(N2CCCC2)c1C#N)C(O)=O Show InChI InChI=1S/C20H22N2O2S/c1-20(2,3)14-8-6-13(7-9-14)16-15(12-21)18(22-10-4-5-11-22)25-17(16)19(23)24/h6-9H,4-5,10-11H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50094024 ((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...) Show SMILES CC(C)S(=O)(=O)NCC(C)c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H22N2O2S/c1-14(2)24(22,23)21-13-15(3)17-8-10-19(11-9-17)18-6-4-16(12-20)5-7-18/h4-11,14-15,21H,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50191962 (3-biphenyl-4-yl-4-cyano-1-methyl-5-methylsulfanyl-...) Show SMILES CSc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-22-18(20(23)24)17(16(12-21)19(22)25-2)15-10-8-14(9-11-15)13-6-4-3-5-7-13/h3-11H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50191962 (3-biphenyl-4-yl-4-cyano-1-methyl-5-methylsulfanyl-...) Show SMILES CSc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-22-18(20(23)24)17(16(12-21)19(22)25-2)15-10-8-14(9-11-15)13-6-4-3-5-7-13/h3-11H,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192218 (3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfonyl)t...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(c1C#N)S(C)(=O)=O)C(O)=O Show InChI InChI=1S/C17H17NO4S2/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(24(4,21)22)23-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192219 (3-(4-tert-butylphenyl)-4-cyano-1-methyl-5-(methylt...) Show SMILES CSc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H20N2O2S/c1-18(2,3)12-8-6-11(7-9-12)14-13(10-19)16(23-5)20(4)15(14)17(21)22/h6-9H,1-5H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192214 (3-(4-tert-butylphenyl)-4-cyano-5-(ethylthio)thioph...) Show SMILES CCSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H19NO2S2/c1-5-22-17-13(10-19)14(15(23-17)16(20)21)11-6-8-12(9-7-11)18(2,3)4/h6-9H,5H2,1-4H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192220 (CHEMBL384175 | ethyl 3-(4-tert-butylphenyl)-4-cyan...) Show SMILES CCOC(=O)c1sc(SC)c(C#N)c1-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H21NO2S2/c1-6-22-17(21)16-15(14(11-20)18(23-5)24-16)12-7-9-13(10-8-12)19(2,3)4/h7-10H,6H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192221 (3-(4-tert-butylphenyl)-4-cyano-5-(trifluoromethyl)...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(c1C#N)C(F)(F)F)C(O)=O Show InChI InChI=1S/C17H14F3NO2S/c1-16(2,3)10-6-4-9(5-7-10)12-11(8-21)14(17(18,19)20)24-13(12)15(22)23/h4-7H,1-3H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	273	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50191959 (3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)thiop...) Show SMILES CSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO2S2/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(21-4)22-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	214	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192219 (3-(4-tert-butylphenyl)-4-cyano-1-methyl-5-(methylt...) Show SMILES CSc1c(C#N)c(c(C(O)=O)n1C)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H20N2O2S/c1-18(2,3)12-8-6-11(7-9-12)14-13(10-19)16(23-5)20(4)15(14)17(21)22/h6-9H,1-5H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	684	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192217 (3-(4-tert-butylphenyl)-4-cyano-5-(pyrrolidin-1-yl)...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(N2CCCC2)c1C#N)C(O)=O Show InChI InChI=1S/C20H22N2O2S/c1-20(2,3)14-8-6-13(7-9-14)16-15(12-21)18(22-10-4-5-11-22)25-17(16)19(23)24/h6-9H,4-5,10-11H2,1-3H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192222 (3-(4-tert-butylphenyl)-4-cyano-5-(dimethylamino)th...) Show SMILES CN(C)c1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H20N2O2S/c1-18(2,3)12-8-6-11(7-9-12)14-13(10-19)16(20(4)5)23-15(14)17(21)22/h6-9H,1-5H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	474	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192216 (3-(4-tert-butylphenyl)-4-cyano-5-ethylthiophene-2-...) Show SMILES CCc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C18H19NO2S/c1-5-14-13(10-19)15(16(22-14)17(20)21)11-6-8-12(9-7-11)18(2,3)4/h6-9H,5H2,1-4H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	216	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192217 (3-(4-tert-butylphenyl)-4-cyano-5-(pyrrolidin-1-yl)...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(N2CCCC2)c1C#N)C(O)=O Show InChI InChI=1S/C20H22N2O2S/c1-20(2,3)14-8-6-13(7-9-14)16-15(12-21)18(22-10-4-5-11-22)25-17(16)19(23)24/h6-9H,4-5,10-11H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192223 (3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfinyl)t...) Show SMILES CS(=O)c1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO3S2/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(23(4)21)22-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	489	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50192218 (3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfonyl)t...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(c1C#N)S(C)(=O)=O)C(O)=O Show InChI InChI=1S/C17H17NO4S2/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(24(4,21)22)23-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	333	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192223 (3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfinyl)t...) Show SMILES CS(=O)c1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO3S2/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(23(4)21)22-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50191959 (3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)thiop...) Show SMILES CSc1sc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO2S2/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(21-4)22-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	97	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192224 (3-(4-tert-butylphenyl)-4-cyano-5-(phenylthio)thiop...) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(sc(Sc2ccccc2)c1C#N)C(O)=O Show InChI InChI=1S/C22H19NO2S2/c1-22(2,3)15-11-9-14(10-12-15)18-17(13-23)21(27-19(18)20(24)25)26-16-7-5-4-6-8-16/h4-12H,1-3H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50192225 (3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)furan...) Show SMILES CSc1oc(C(O)=O)c(c1C#N)-c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C17H17NO3S/c1-17(2,3)11-7-5-10(6-8-11)13-12(9-18)16(22-4)21-14(13)15(19)20/h5-8H,1-4H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50094024 ((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...) Show SMILES CC(C)S(=O)(=O)NCC(C)c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C19H22N2O2S/c1-14(2)24(22,23)21-13-15(3)17-8-10-19(11-9-17)18-6-4-16(12-20)5-7-18/h4-11,14-15,21H,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	559	n/a	n/a	n/a	n/a
Lilly S.A. Curated by ChEMBL					Assay Description Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assay				Bioorg Med Chem Lett 16: 5057-61 (2006) Article DOI: 10.1016/j.bmcl.2006.07.035 BindingDB Entry DOI: 10.7270/Q24749H7
					More data for this Ligand-Target Pair				3D Structure (crystal)

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