Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254439 (CHEMBL4091459) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254442 (CHEMBL4095993) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254402 (CHEMBL4098431) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254387 (CHEMBL4062193) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of rat TRPA1 at a holding potential of 15 mV measured after 1 min by whole-cell manual patch clamp electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254387 (CHEMBL4062193) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254387 (CHEMBL4062193) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254406 (CHEMBL4103611) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254406 (CHEMBL4103611) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254442 (CHEMBL4095993) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254403 (CHEMBL4088258) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254402 (CHEMBL4098431) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254440 (CHEMBL4063630) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254440 (CHEMBL4063630) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254439 (CHEMBL4091459) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254487 (CHEMBL4060024) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254403 (CHEMBL4088258) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254438 (CHEMBL4100238) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254386 (CHEMBL4073272) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254487 (CHEMBL4060024) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254386 (CHEMBL4073272) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254388 (CHEMBL4101680) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 195 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of rat TRPA1 at a holding potential of 15 mV measured after 1 min by whole-cell manual patch clamp electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254427 (CHEMBL4067095) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 216 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254388 (CHEMBL4101680) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254441 (CHEMBL4102407) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254427 (CHEMBL4067095) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254385 (CHEMBL4083680) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 271 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254426 (CHEMBL4061751) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 329 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254387 (CHEMBL4062193) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254441 (CHEMBL4102407) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254489 (CHEMBL4075615) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 453 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254401 (CHEMBL4093377) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length human TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254488 (CHEMBL4072845) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 645 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254388 (CHEMBL4101680) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 686 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254438 (CHEMBL4100238) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 748 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254425 (CHEMBL4067996) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 813 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254385 (CHEMBL4083680) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254404 (CHEMBL4061022) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus) | BDBM50254428 (CHEMBL4079870) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of full length rat TRPA1 at a holding potential of 15 mV measured after 1 min by PatchXpress electrophysiology assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254426 (CHEMBL4061751) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254401 (CHEMBL4093377) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254425 (CHEMBL4067996) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily KQT member 1 (Homo sapiens (Human)) | BDBM50254401 (CHEMBL4093377) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of KCNQ1 (unknown origin) | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily KQT member 1 (Homo sapiens (Human)) | BDBM50254387 (CHEMBL4062193) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of KCNQ1 (unknown origin) | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254489 (CHEMBL4075615) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily KQT member 1 (Homo sapiens (Human)) | BDBM50254388 (CHEMBL4101680) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of KCNQ1 (unknown origin) | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254405 (CHEMBL4082907) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254428 (CHEMBL4079870) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human)) | BDBM50254401 (CHEMBL4093377) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of Nav1.5 (unknown origin) | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50254387 (CHEMBL4062193) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Inhibition of Nav1.7 (unknown origin) | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM50254453 (CHEMBL4079487) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Worldwide Medicinal Chemistry, Neuroscience and Pain Research Unit, Portway Building, Granta Park, Great Abington, Cambridgeshire CB21 6GS, U.K. Curated by ChEMBL | Assay Description Antagonist activity at human TRPA1 by calcium flux based FLIPR assay | ACS Med Chem Lett 8: 666-671 (2017) Article DOI: 10.1021/acsmedchemlett.7b00140 BindingDB Entry DOI: 10.7270/Q2C24ZWG | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 71 total ) | Next | Last >> |