Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300554 (((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300554 (((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300547 (2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300547 (2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300551 (2,3,7,8-Tetrahydroxy-5-methyl-benzo[c]phenanthridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300551 (2,3,7,8-Tetrahydroxy-5-methyl-benzo[c]phenanthridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300548 (3,4,10,11-Tetrahydroxy-8-methyl-isoquino[3,2-a]iso...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300545 (CHEMBL573174 | tetrahydroxycanadine hydrochloride) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300548 (3,4,10,11-Tetrahydroxy-8-methyl-isoquino[3,2-a]iso...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300552 (2,3-Dihydroxy-7,8-dimethoxy-5-methyl-benzo[c]phena...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300546 (6,7-Dimethoxy-1-methyl-3-naphthalen-2-yl-isoquinol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300549 (2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300552 (2,3-Dihydroxy-7,8-dimethoxy-5-methyl-benzo[c]phena...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300546 (6,7-Dimethoxy-1-methyl-3-naphthalen-2-yl-isoquinol...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM25524 (17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM25524 (17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300549 (2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300550 (3-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-1-methyl-is...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division control protein 42 homolog (Homo sapiens (Human)) | BDBM50300545 (CHEMBL573174 | tetrahydroxycanadine hydrochloride) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human)) | BDBM50300550 (3-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-1-methyl-is...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.04E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Exonhit Therapeutics Curated by ChEMBL | Assay Description Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | Bioorg Med Chem Lett 19: 5594-8 (2009) Article DOI: 10.1016/j.bmcl.2009.08.037 BindingDB Entry DOI: 10.7270/Q27P8ZF4 | |||||||||||
More data for this Ligand-Target Pair |