Compile Data Set for Download or QSAR

Found 28 hits with Last Name = 'ramos' and Initial = 'mt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50014335 (CHEMBL1164066) Show SMILES CC1(C)CC(=O)C2=C(C1)NC(=CC2c1ccccc1)c1ccccc1 |c:6,11| Show InChI InChI=1S/C23H23NO/c1-23(2)14-20-22(21(25)15-23)18(16-9-5-3-6-10-16)13-19(24-20)17-11-7-4-8-12-17/h3-13,18,24H,14-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014335 (CHEMBL1164066) Show SMILES CC1(C)CC(=O)C2=C(C1)NC(=CC2c1ccccc1)c1ccccc1 |c:6,11| Show InChI InChI=1S/C23H23NO/c1-23(2)14-20-22(21(25)15-23)18(16-9-5-3-6-10-16)13-19(24-20)17-11-7-4-8-12-17/h3-13,18,24H,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014177 (CHEMBL3221239) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccccc1)c1ccc(Cl)cc1 |c:5,9| Show InChI InChI=1S/C21H20ClNO2/c1-3-25-21(24)20-14(2)23-19(16-9-11-17(22)12-10-16)13-18(20)15-7-5-4-6-8-15/h4-13,18,23H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014173 (CHEMBL3260888) Show SMILES CCCC1=C(C(C=C(N1)c1ccccc1)c1ccccc1)C(=O)OCC |c:6,t:3| Show InChI InChI=1S/C23H25NO2/c1-3-11-20-22(23(25)26-4-2)19(17-12-7-5-8-13-17)16-21(24-20)18-14-9-6-10-15-18/h5-10,12-16,19,24H,3-4,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50014300 (CHEMBL3260892) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(C)cc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C22H23NO2/c1-4-25-22(24)21-16(3)23-20(18-8-6-5-7-9-18)14-19(21)17-12-10-15(2)11-13-17/h5-14,19,23H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014313 (CHEMBL3260894) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(cc1)[N+]([O-])=O)c1ccccc1 |c:5,9| Show InChI InChI=1S/C21H20N2O4/c1-3-27-21(24)20-14(2)22-19(16-7-5-4-6-8-16)13-18(20)15-9-11-17(12-10-15)23(25)26/h4-13,18,22H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014172 (CHEMBL3221238) Show SMILES CCOC(=O)C1=C(CC)NC(=CC1c1ccccc1)c1ccccc1 |c:5,10| Show InChI InChI=1S/C22H23NO2/c1-3-19-21(22(24)25-4-2)18(16-11-7-5-8-12-16)15-20(23-19)17-13-9-6-10-14-17/h5-15,18,23H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014327 (CHEMBL3221246) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1cccs1)c1ccc(C)cc1 |c:5,9| Show InChI InChI=1S/C20H21NO2S/c1-4-23-20(22)19-14(3)21-17(15-9-7-13(2)8-10-15)12-16(19)18-6-5-11-24-18/h5-12,16,21H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014238 (CHEMBL3260891) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1cccc(OC)c1)c1ccc(Cl)cc1 |c:5,9| Show InChI InChI=1S/C22H22ClNO3/c1-4-27-22(25)21-14(2)24-20(15-8-10-17(23)11-9-15)13-19(21)16-6-5-7-18(12-16)26-3/h5-13,19,24H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014303 (CHEMBL3260893) Show SMILES CC1=C(C(C=C(N1)c1ccc(Cl)cc1)c1ccccc1)C(=O)OCC=C |c:4,t:1| Show InChI InChI=1S/C22H20ClNO2/c1-3-13-26-22(25)21-15(2)24-20(17-9-11-18(23)12-10-17)14-19(21)16-7-5-4-6-8-16/h3-12,14,19,24H,1,13H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014171 (CHEMBL3221248) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccccc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C21H21NO2/c1-3-24-21(23)20-15(2)22-19(17-12-8-5-9-13-17)14-18(20)16-10-6-4-7-11-16/h4-14,18,22H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50014333 (CHEMBL3221247) Show SMILES C\C(=C/c1ccccc1)C1C=C(NC(C)=C1C(=O)SC(C)(C)C)c1ccccc1 |c:11,15| Show InChI InChI=1S/C26H29NOS/c1-18(16-20-12-8-6-9-13-20)22-17-23(21-14-10-7-11-15-21)27-19(2)24(22)25(28)29-26(3,4)5/h6-17,22,27H,1-5H3/b18-16+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014300 (CHEMBL3260892) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(C)cc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C22H23NO2/c1-4-25-22(24)21-16(3)23-20(18-8-6-5-7-9-18)14-19(21)17-12-10-15(2)11-13-17/h5-14,19,23H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014334 (CHEMBL1164407) Show SMILES O=C1CCCC2=C1C(C=C(N2)c1ccccc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C21H19NO/c23-20-13-7-12-18-21(20)17(15-8-3-1-4-9-15)14-19(22-18)16-10-5-2-6-11-16/h1-6,8-11,14,17,22H,7,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014235 (CHEMBL3221242) Show SMILES COc1ccc(cc1)C1C=C(NC(C)=C1C(=O)SC(C)(C)C)c1ccccc1 |c:10,14| Show InChI InChI=1S/C24H27NO2S/c1-16-22(23(26)28-24(2,3)4)20(17-11-13-19(27-5)14-12-17)15-21(25-16)18-9-7-6-8-10-18/h6-15,20,25H,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014176 (CHEMBL3221240) Show SMILES CC(=O)C1=C(C)NC(=CC1c1ccccc1)c1ccccc1 |c:3,7| Show InChI InChI=1S/C20H19NO/c1-14-20(15(2)22)18(16-9-5-3-6-10-16)13-19(21-14)17-11-7-4-8-12-17/h3-13,18,21H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014178 (CHEMBL3260889) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(Cl)cc1)c1ccc(Cl)cc1 |c:5,9| Show InChI InChI=1S/C21H19Cl2NO2/c1-3-26-21(25)20-13(2)24-19(15-6-10-17(23)11-7-15)12-18(20)14-4-8-16(22)9-5-14/h4-12,18,24H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014179 (CHEMBL3260890) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(OC)cc1)c1ccccc1 |c:5,9| Show InChI InChI=1S/C22H23NO3/c1-4-26-22(24)21-15(2)23-20(17-8-6-5-7-9-17)14-19(21)16-10-12-18(25-3)13-11-16/h5-14,19,23H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014317 (CHEMBL3260895) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccccc1[N+]([O-])=O)c1ccc(C)cc1 |c:5,9| Show InChI InChI=1S/C22H22N2O4/c1-4-28-22(25)21-15(3)23-19(16-11-9-14(2)10-12-16)13-18(21)17-7-5-6-8-20(17)24(26)27/h5-13,18,23H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014328 (CHEMBL3261115) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccc(C)cc1)c1ccco1 |c:5,9| Show InChI InChI=1S/C20H21NO3/c1-4-23-20(22)19-14(3)21-17(18-6-5-11-24-18)12-16(19)15-9-7-13(2)8-10-15/h5-12,16,21H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014257 (CHEMBL3221244) Show SMILES CC1=C(C(C=C(N1)c1ccccc1)c1ccc(C)cc1)C(=O)SC(C)(C)C |c:4,t:1| Show InChI InChI=1S/C24H27NOS/c1-16-11-13-18(14-12-16)20-15-21(19-9-7-6-8-10-19)25-17(2)22(20)23(26)27-24(3,4)5/h6-15,20,25H,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014321 (CHEMBL3260896) Show SMILES CCOC(=O)C1=C(C)NC(=CC1c1ccccc1[N+]([O-])=O)c1ccc(Cl)cc1 |c:5,9| Show InChI InChI=1S/C21H19ClN2O4/c1-3-28-21(25)20-13(2)23-18(14-8-10-15(22)11-9-14)12-17(20)16-6-4-5-7-19(16)24(26)27/h4-12,17,23H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014248 (CHEMBL3221243) Show SMILES CC1=C(C(C=C(N1)c1ccc(C)cc1)c1ccc(Br)cc1)C(=O)SC(C)(C)C |c:4,t:1| Show InChI InChI=1S/C24H26BrNOS/c1-15-6-8-18(9-7-15)21-14-20(17-10-12-19(25)13-11-17)22(16(2)26-21)23(27)28-24(3,4)5/h6-14,20,26H,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014333 (CHEMBL3221247) Show SMILES C\C(=C/c1ccccc1)C1C=C(NC(C)=C1C(=O)SC(C)(C)C)c1ccccc1 |c:11,15| Show InChI InChI=1S/C26H29NOS/c1-18(16-20-12-8-6-9-13-20)22-17-23(21-14-10-7-11-15-21)27-19(2)24(22)25(28)29-26(3,4)5/h6-17,22,27H,1-5H3/b18-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014175 (CHEMBL3221241) Show SMILES CC1=C(C(C=C(N1)c1ccccc1)c1ccccc1)C(=O)SC(C)(C)C |c:4,t:1| Show InChI InChI=1S/C23H25NOS/c1-16-21(22(25)26-23(2,3)4)19(17-11-7-5-8-12-17)15-20(24-16)18-13-9-6-10-14-18/h5-15,19,24H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Homo sapiens (Human))	BDBM50014272 (CHEMBL3221245) Show SMILES CC1=C(C(C=C(N1)c1ccc(C)cc1)c1ccc(C)cc1)C(=O)SC(C)(C)C |c:4,t:1| Show InChI InChI=1S/C25H29NOS/c1-16-7-11-19(12-8-16)21-15-22(20-13-9-17(2)10-14-20)26-18(3)23(21)24(27)28-25(4,5)6/h7-15,21,26H,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by ...				J Med Chem 57: 4313-23 (2014) Article DOI: 10.1021/jm500263v BindingDB Entry DOI: 10.7270/Q22R3T6K
					More data for this Ligand-Target Pair