Compile Data Set for Download or QSAR

Found 336 hits with Last Name = 'schuster' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127593 (US8791118, 156) Show SMILES COc1cc(CO)ccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C27H29N5O3/c1-18(7-6-10-19-8-4-3-5-9-19)29-27(34)32-25-14-13-22-26(31-25)30-23(16-28-22)21-12-11-20(17-33)15-24(21)35-2/h3-5,8-9,11-16,18,33H,6-7,10,17H2,1-2H3,(H2,29,30,31,32,34)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127596 (US8791118, 159) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)-c1cn[nH]c1 Show InChI InChI=1S/C21H21N7O/c29-21(22-11-5-4-8-15-6-2-1-3-7-15)28-19-10-9-17-20(27-19)26-18(14-23-17)16-12-24-25-13-16/h1-3,6-7,9-10,12-14H,4-5,8,11H2,(H,24,25)(H2,22,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127597 (US8791118, 160) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H23N5O2/c30-19-11-9-18(10-12-19)21-16-26-20-13-14-22(28-23(20)27-21)29-24(31)25-15-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-14,16,30H,4-5,8,15H2,(H2,25,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127595 (US8791118, 158) Show SMILES COc1c(CO)cccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C27H29N5O3/c1-18(8-6-11-19-9-4-3-5-10-19)29-27(34)32-24-15-14-22-26(31-24)30-23(16-28-22)21-13-7-12-20(17-33)25(21)35-2/h3-5,7,9-10,12-16,18,33H,6,8,11,17H2,1-2H3,(H2,29,30,31,32,34)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127620 (US8791118, 194) Show SMILES COc1cc(ccc1C(O)=O)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C26H25N5O4/c1-35-22-15-18(10-11-19(22)25(32)33)21-16-28-20-12-13-23(30-24(20)29-21)31-26(34)27-14-6-5-9-17-7-3-2-4-8-17/h2-4,7-8,10-13,15-16H,5-6,9,14H2,1H3,(H,32,33)(H2,27,29,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127621 (US8791118, 195) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(C[C@H](N)C(O)=O)cc1 |r| Show InChI InChI=1S/C28H30N6O3/c1-18(6-5-9-19-7-3-2-4-8-19)31-28(37)34-25-15-14-23-26(33-25)32-24(17-30-23)21-12-10-20(11-13-21)16-22(29)27(35)36/h2-4,7-8,10-15,17-18,22H,5-6,9,16,29H2,1H3,(H,35,36)(H2,31,32,33,34,37)/t18-,22+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127600 (US8791118, 163) Show SMILES FC(F)Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C23H23F2N7O/c24-20(25)15-32-14-17(12-28-32)19-13-27-18-9-10-21(30-22(18)29-19)31-23(33)26-11-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9-10,12-14,20H,4-5,8,11,15H2,(H2,26,29,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127601 (US8791118, 164) Show SMILES CC(CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C23H25N7O/c1-16(7-6-10-17-8-4-3-5-9-17)26-23(31)29-21-12-11-19-22(28-21)27-20(14-24-19)18-13-25-30(2)15-18/h3-5,8-9,11-16H,6-7,10H2,1-2H3,(H2,26,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127599 (US8791118, 162) Show SMILES OCCCn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H27N7O2/c32-14-6-13-31-17-19(15-27-31)21-16-26-20-10-11-22(29-23(20)28-21)30-24(33)25-12-5-4-9-18-7-2-1-3-8-18/h1-3,7-8,10-11,15-17,32H,4-6,9,12-14H2,(H2,25,28,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127598 (US8791118, 161) Show SMILES COc1ncccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C25H26N6O2/c1-17(8-6-11-18-9-4-3-5-10-18)28-25(32)31-22-14-13-20-23(30-22)29-21(16-27-20)19-12-7-15-26-24(19)33-2/h3-5,7,9-10,12-17H,6,8,11H2,1-2H3,(H2,28,29,30,31,32)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127594 (US8791118, 157) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccncc1 |r| Show InChI InChI=1S/C24H24N6O/c1-17(6-5-9-18-7-3-2-4-8-18)27-24(31)30-22-11-10-20-23(29-22)28-21(16-26-20)19-12-14-25-15-13-19/h2-4,7-8,10-17H,5-6,9H2,1H3,(H2,27,28,29,30,31)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127603 (US8791118, 166) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C23H28N6O2/c1-17(6-5-9-18-7-3-2-4-8-18)25-23(30)27-20-11-10-19-22(26-20)28-21(16-24-19)29-12-14-31-15-13-29/h2-4,7-8,10-11,16-17H,5-6,9,12-15H2,1H3,(H2,25,26,27,28,30)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127624 (US8791118, 198) Show SMILES OC(=O)c1cccc(c1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C25H23N5O3/c31-24(32)19-11-6-10-18(15-19)21-16-27-20-12-13-22(29-23(20)28-21)30-25(33)26-14-5-4-9-17-7-2-1-3-8-17/h1-3,6-8,10-13,15-16H,4-5,9,14H2,(H,31,32)(H2,26,28,29,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127606 (US8791118, 169) Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCC(C)(C)c3ccccc3)nc2n1 Show InChI InChI=1S/C24H27N7O/c1-24(2,18-8-5-4-6-9-18)12-7-13-25-23(32)30-21-11-10-19-22(29-21)28-20(15-26-19)17-14-27-31(3)16-17/h4-6,8-11,14-16H,7,12-13H2,1-3H3,(H2,25,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127605 (US8791118, 168) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(CCN2CCOCC2)c1 |r| Show InChI InChI=1S/C28H34N8O2/c1-21(6-5-9-22-7-3-2-4-8-22)31-28(37)34-26-11-10-24-27(33-26)32-25(19-29-24)23-18-30-36(20-23)13-12-35-14-16-38-17-15-35/h2-4,7-8,10-11,18-21H,5-6,9,12-17H2,1H3,(H2,31,32,33,34,37)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127604 (US8791118, 167) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(CO)cc1 |r| Show InChI InChI=1S/C26H27N5O2/c1-18(6-5-9-19-7-3-2-4-8-19)28-26(33)31-24-15-14-22-25(30-24)29-23(16-27-22)21-12-10-20(17-32)11-13-21/h2-4,7-8,10-16,18,32H,5-6,9,17H2,1H3,(H2,28,29,30,31,33)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127602 (US8791118, 165) Show SMILES OP(O)(=O)Oc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H24N5O5P/c30-24(25-15-5-4-8-17-6-2-1-3-7-17)29-22-14-13-20-23(28-22)27-21(16-26-20)18-9-11-19(12-10-18)34-35(31,32)33/h1-3,6-7,9-14,16H,4-5,8,15H2,(H2,31,32,33)(H2,25,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127607 (US8791118, 170) Show SMILES CCCn1cc(cn1)-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C25H29N7O/c1-3-14-32-17-20(15-27-32)22-16-26-21-12-13-23(30-24(21)29-22)31-25(33)28-18(2)8-7-11-19-9-5-4-6-10-19/h4-6,9-10,12-13,15-18H,3,7-8,11,14H2,1-2H3,(H2,28,29,30,31,33)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127608 (US8791118, 171) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C22H23N7O/c1-15(6-5-9-16-7-3-2-4-8-16)26-22(30)29-20-11-10-18-21(28-20)27-19(14-23-18)17-12-24-25-13-17/h2-4,7-8,10-15H,5-6,9H2,1H3,(H,24,25)(H2,26,27,28,29,30)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127592 (US8791118, 155) Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C22H23N7O/c1-29-15-17(13-25-29)19-14-24-18-10-11-20(27-21(18)26-19)28-22(30)23-12-6-5-9-16-7-3-2-4-8-16/h2-4,7-8,10-11,13-15H,5-6,9,12H2,1H3,(H2,23,26,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127590 (US8791118, 108) Show SMILES CCn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C23H25N7O/c1-2-30-16-18(14-26-30)20-15-25-19-11-12-21(28-22(19)27-20)29-23(31)24-13-7-6-10-17-8-4-3-5-9-17/h3-5,8-9,11-12,14-16H,2,6-7,10,13H2,1H3,(H2,24,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127622 (US8791118, 196) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C26H25N5O3/c1-17(7-5-10-18-8-3-2-4-9-18)28-26(34)31-23-14-13-21-24(30-23)29-22(16-27-21)19-11-6-12-20(15-19)25(32)33/h2-4,6,8-9,11-17H,5,7,10H2,1H3,(H,32,33)(H2,28,29,30,31,34)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127619 (US8791118, 189) Show SMILES OCCn1cc(cn1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C23H25N7O2/c31-13-12-30-16-18(14-26-30)20-15-25-19-9-10-21(28-22(19)27-20)29-23(32)24-11-5-4-8-17-6-2-1-3-7-17/h1-3,6-7,9-10,14-16,31H,4-5,8,11-13H2,(H2,24,27,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127591 (US8791118, 127) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)-c1cnn(CCN2CCOCC2)c1 Show InChI InChI=1S/C27H32N8O2/c36-27(28-11-5-4-8-21-6-2-1-3-7-21)33-25-10-9-23-26(32-25)31-24(19-29-23)22-18-30-35(20-22)13-12-34-14-16-37-17-15-34/h1-3,6-7,9-10,18-20H,4-5,8,11-17H2,(H2,28,31,32,33,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127623 (US8791118, 197) Show SMILES N[C@@H](Cc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1)C(O)=O |r| Show InChI InChI=1S/C27H28N6O3/c28-21(26(34)35)16-19-9-11-20(12-10-19)23-17-30-22-13-14-24(32-25(22)31-23)33-27(36)29-15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-14,17,21H,4-5,8,15-16,28H2,(H,34,35)(H2,29,31,32,33,36)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127610 (US8791118, 173) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)N1CCCC1 |r| Show InChI InChI=1S/C23H28N6O/c1-17(8-7-11-18-9-3-2-4-10-18)25-23(30)27-20-13-12-19-22(26-20)28-21(16-24-19)29-14-5-6-15-29/h2-4,9-10,12-13,16-17H,5-8,11,14-15H2,1H3,(H2,25,26,27,28,30)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127609 (US8791118, 172) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)N1CCCC1 Show InChI InChI=1S/C22H26N6O/c29-22(23-13-5-4-10-17-8-2-1-3-9-17)26-19-12-11-18-21(25-19)27-20(16-24-18)28-14-6-7-15-28/h1-3,8-9,11-12,16H,4-7,10,13-15H2,(H2,23,25,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127618 (US8791118, 181) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cccc(CO)c1 |r| Show InChI InChI=1S/C26H27N5O2/c1-18(7-5-10-19-8-3-2-4-9-19)28-26(33)31-24-14-13-22-25(30-24)29-23(16-27-22)21-12-6-11-20(15-21)17-32/h2-4,6,8-9,11-16,18,32H,5,7,10,17H2,1H3,(H2,28,29,30,31,33)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127617 (US8791118, 180) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(C)c1 |r| Show InChI InChI=1S/C23H25N7O/c1-16(7-6-10-17-8-4-3-5-9-17)26-23(31)29-21-12-11-19-22(28-21)27-20(14-24-19)18-13-25-30(2)15-18/h3-5,8-9,11-16H,6-7,10H2,1-2H3,(H2,26,27,28,29,31)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127616 (US8791118, 179) Show SMILES COc1ccccc1-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C26H27N5O2/c1-18(9-8-12-19-10-4-3-5-11-19)28-26(32)31-24-16-15-21-25(30-24)29-22(17-27-21)20-13-6-7-14-23(20)33-2/h3-7,10-11,13-18H,8-9,12H2,1-2H3,(H2,28,29,30,31,32)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127615 (US8791118, 178) Show SMILES COc1ccc(cc1OC)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C26H27N5O3/c1-33-22-13-11-19(16-23(22)34-2)21-17-28-20-12-14-24(30-25(20)29-21)31-26(32)27-15-7-6-10-18-8-4-3-5-9-18/h3-5,8-9,11-14,16-17H,6-7,10,15H2,1-2H3,(H2,27,29,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127614 (US8791118, 177) Show SMILES C[C@H](CCCc1ccccc1)NC(=O)Nc1ccc2ncc(nc2n1)-c1c(C)n[nH]c1C |r| Show InChI InChI=1S/C24H27N7O/c1-15(8-7-11-18-9-5-4-6-10-18)26-24(32)29-21-13-12-19-23(28-21)27-20(14-25-19)22-16(2)30-31-17(22)3/h4-6,9-10,12-15H,7-8,11H2,1-3H3,(H,30,31)(H2,26,27,28,29,32)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127613 (US8791118, 176) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)N1CCOCC1 Show InChI InChI=1S/C22H26N6O2/c29-22(23-11-5-4-8-17-6-2-1-3-7-17)26-19-10-9-18-21(25-19)27-20(16-24-18)28-12-14-30-15-13-28/h1-3,6-7,9-10,16H,4-5,8,11-15H2,(H2,23,25,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127611 (US8791118, 174) Show SMILES Oc1ccc(cc1F)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C24H22FN5O2/c25-18-14-17(9-11-21(18)31)20-15-27-19-10-12-22(29-23(19)28-20)30-24(32)26-13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9-12,14-15,31H,4-5,8,13H2,(H2,26,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127612 (US8791118, 175) Show SMILES OCc1cccc(c1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C25H25N5O2/c31-17-19-10-6-11-20(15-19)22-16-27-21-12-13-23(29-24(21)28-22)30-25(32)26-14-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-13,15-16,31H,4-5,9,14,17H2,(H2,26,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM142655 (US8937068, 43) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(O)cc1 Show InChI InChI=1S/C16H15N5O2/c1-2-17-16(23)21-14-8-7-12-15(20-14)19-13(9-18-12)10-3-5-11(22)6-4-10/h3-9,22H,2H2,1H3,(H2,17,19,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127627 (US8791118, 203) Show SMILES COCc1cccc(c1)-c1cnc2ccc(NC(=O)N[C@H](C)CCCc3ccccc3)nc2n1 |r| Show InChI InChI=1S/C27H29N5O2/c1-19(8-6-11-20-9-4-3-5-10-20)29-27(33)32-25-15-14-23-26(31-25)30-24(17-28-23)22-13-7-12-21(16-22)18-34-2/h3-5,7,9-10,12-17,19H,6,8,11,18H2,1-2H3,(H2,29,30,31,32,33)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50050853 (CHEMBL3318029) Show SMILES Cn1cc(cn1)-c1cnc2ccc(NC(=O)NCc3ccccc3)nc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-23-26)15-9-18-17(21-11-15)7-8-19(24-18)25-20(27)22-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,22,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127625 (US8791118, 201) Show SMILES OCCOCCOc1ccc(cc1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C28H31N5O4/c34-16-17-36-18-19-37-23-11-9-22(10-12-23)25-20-30-24-13-14-26(32-27(24)31-25)33-28(35)29-15-5-4-8-21-6-2-1-3-7-21/h1-3,6-7,9-14,20,34H,4-5,8,15-19H2,(H2,29,31,32,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127626 (US8791118, 202) Show SMILES O=C(NCCCCc1ccccc1)Nc1ccc2ncc(nc2n1)-c1ccc(OCCN2CCOCC2)cc1 Show InChI InChI=1S/C30H34N6O3/c37-30(31-15-5-4-8-23-6-2-1-3-7-23)35-28-14-13-26-29(34-28)33-27(22-32-26)24-9-11-25(12-10-24)39-21-18-36-16-19-38-20-17-36/h1-3,6-7,9-14,22H,4-5,8,15-21H2,(H2,31,33,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM47103 (US8937068, 124 | US8937068, 193) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(O)c(OC)c1 Show InChI InChI=1S/C17H17N5O3/c1-3-18-17(24)22-15-7-5-11-16(21-15)20-12(9-19-11)10-4-6-13(23)14(8-10)25-2/h4-9,23H,3H2,1-2H3,(H2,18,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50050860 (CHEMBL3318034) Show SMILES Cn1cc(cn1)-c1cnc2c(NC(=O)NCc3ccccc3)ccnc2c1 Show InChI InChI=1S/C20H18N6O/c1-26-13-16(12-24-26)15-9-18-19(22-11-15)17(7-8-21-18)25-20(27)23-10-14-5-3-2-4-6-14/h2-9,11-13H,10H2,1H3,(H2,21,23,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM142653 (US8937068, 25) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=O)NCC=C)nc2n1 Show InChI InChI=1S/C17H15N5O2/c1-2-9-18-17(24)22-15-8-7-13-16(21-15)20-14(10-19-13)11-3-5-12(23)6-4-11/h2-8,10,23H,1,9H2,(H2,18,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM142681 (US8937068, 171) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(Cl)cc1OC Show InChI InChI=1S/C17H16ClN5O2/c1-3-19-17(24)23-15-7-6-12-16(22-15)21-13(9-20-12)11-5-4-10(18)8-14(11)25-2/h4-9H,3H2,1-2H3,(H2,19,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50050861 (CHEMBL3318035) Show SMILES Cn1cc(cn1)-c1cnc2c(NC(=O)NCCc3ccccc3)ccnc2c1 Show InChI InChI=1S/C21H20N6O/c1-27-14-17(13-25-27)16-11-19-20(24-12-16)18(8-10-22-19)26-21(28)23-9-7-15-5-3-2-4-6-15/h2-6,8,10-14H,7,9H2,1H3,(H2,22,23,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM142674 (US8937068, 163) Show SMILES CCNC(=O)Nc1ccc2ncc(Nc3ccc(C)c(OC)c3)nc2n1 Show InChI InChI=1S/C18H20N6O2/c1-4-19-18(25)24-15-8-7-13-17(22-15)23-16(10-20-13)21-12-6-5-11(2)14(9-12)26-3/h5-10H,4H2,1-3H3,(H3,19,21,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM142680 (US8937068, 170) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(O)cc1Cl Show InChI InChI=1S/C16H14ClN5O2/c1-2-18-16(24)22-14-6-5-12-15(21-14)20-13(8-19-12)10-4-3-9(23)7-11(10)17/h3-8,23H,2H2,1H3,(H2,18,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM47096 (US8937068, 1 | US8937068, 151) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1cccc(O)c1 Show InChI InChI=1S/C16H15N5O2/c1-2-17-16(23)21-14-7-6-12-15(20-14)19-13(9-18-12)10-4-3-5-11(22)8-10/h3-9,22H,2H2,1H3,(H2,17,19,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM47096 (US8937068, 1 | US8937068, 151) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1cccc(O)c1 Show InChI InChI=1S/C16H15N5O2/c1-2-17-16(23)21-14-7-6-12-15(20-14)19-13(9-18-12)10-4-3-5-11(22)8-10/h3-9,22H,2H2,1H3,(H2,17,19,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM142683 (US8937068, 173) Show SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C14H15N7O/c1-3-15-14(22)20-12-5-4-10-13(19-12)18-11(7-16-10)9-6-17-21(2)8-9/h4-8H,3H2,1-2H3,(H2,15,18,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair

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