Found 111 hits with Last Name = 'seim' and Initial = 'mr' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13014
(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)Show InChI InChI=1S/C9H9Cl2N/c10-8-2-1-6-3-4-12-5-7(6)9(8)11/h1-2,12H,3-5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank MMDB PDB Article PubMed
| 3.10 | -50.5 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13014
(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)Show InChI InChI=1S/C9H9Cl2N/c10-8-2-1-6-3-4-12-5-7(6)9(8)11/h1-2,12H,3-5H2 | PDB MMDB
Reactome pathway KEGG
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| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM13014
(7,8-Dichloro-1,2,3,4-tetrahydro-isoquinoline; hydr...)Show InChI InChI=1S/C9H9Cl2N/c10-8-2-1-6-3-4-12-5-7(6)9(8)11/h1-2,12H,3-5H2 | PDB
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| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50100949
((7-Bromo-1,2,3,4-tetrahydro-isoquinolin-3-yl)-meth...)Show InChI InChI=1S/C10H12BrNO/c11-9-2-1-7-4-10(6-13)12-5-8(7)3-9/h1-3,10,12-13H,4-6H2 | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity against Human phenylethanolamine N-methyltransferase |
Bioorg Med Chem Lett 15: 1143-7 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.013 BindingDB Entry DOI: 10.7270/Q2X63MFG |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50077544
((S)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)Show InChI InChI=1S/C10H12N2O2/c1-7-4-8-2-3-10(12(13)14)5-9(8)6-11-7/h2-3,5,7,11H,4,6H2,1H3/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of human PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50174121
(7-bromo-3-methyl-1,2,3,4-tetrahydroisoquinoline | ...)Show InChI InChI=1S/C10H12BrN/c1-7-4-8-2-3-10(11)5-9(8)6-12-7/h2-3,5,7,12H,4,6H2,1H3 | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of human PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13027
(3-(hydroxymethyl)-N-(2,2,2-trifluoroethyl)-1,2,3,4...)Show InChI InChI=1S/C12H15F3N2O3S/c13-12(14,15)7-17-21(19,20)11-2-1-8-3-10(6-18)16-5-9(8)4-11/h1-2,4,10,16-18H,3,5-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 23 | -45.4 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50077537
((+)-(7-nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)me...)Show InChI InChI=1S/C10H12N2O3/c13-6-9-3-7-1-2-10(12(14)15)4-8(7)5-11-9/h1-2,4,9,11,13H,3,5-6H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid PDB UniChem
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| PDB Article PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity against Human phenylethanolamine N-methyltransferase |
Bioorg Med Chem Lett 15: 1143-7 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.013 BindingDB Entry DOI: 10.7270/Q2X63MFG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13023
(3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-7...)Show InChI InChI=1S/C10H14N2O3S/c11-16(14,15)10-2-1-7-3-9(6-13)12-5-8(7)4-10/h1-2,4,9,12-13H,3,5-6H2,(H2,11,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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| Article PubMed
| 52 | -43.2 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50072977
(7-Bromo-1,2,3,4-tetrahydro-isoquinoline | 7-bromo-...)Show InChI InChI=1S/C9H10BrN/c10-9-2-1-7-3-4-11-6-8(7)5-9/h1-2,5,11H,3-4,6H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50072977
(7-Bromo-1,2,3,4-tetrahydro-isoquinoline | 7-bromo-...)Show InChI InChI=1S/C9H10BrN/c10-9-2-1-7-3-4-11-6-8(7)5-9/h1-2,5,11H,3-4,6H2 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
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| Article PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13025
(7-sulfonamide-THIQ 15 | CHEMBL176112 | N-(4-chloro...)Show InChI InChI=1S/C16H17ClN2O3S/c17-13-2-4-14(5-3-13)19-23(21,22)16-6-1-11-7-15(10-20)18-9-12(11)8-16/h1-6,8,15,18-20H,7,9-10H2 | PDB MMDB
Reactome pathway KEGG
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| PDB Article PubMed
| 63 | -42.8 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50186678
((+/-)-3-difluoromethyl-7-trifluoromethyl-1,2,3,4-t...)Show InChI InChI=1S/C11H10F5N/c12-10(13)9-4-6-1-2-8(11(14,15)16)3-7(6)5-17-9/h1-3,9-10,17H,4-5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50227503
(3-Methyl-1,2,3,4-tetrahydro-benzo[4,5]thieno[3,2-c...)Show InChI InChI=1S/C12H13NS/c1-8-6-12-10(7-13-8)9-4-2-3-5-11(9)14-12/h2-5,8,13H,6-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50077543
(3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoline |...)Show InChI InChI=1S/C10H12N2O2/c1-7-4-8-2-3-10(12(13)14)5-9(8)6-11-7/h2-3,5,7,11H,4,6H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50186676
((+/-)-3-difluoromethyl-7-bromo-1,2,3,4-tetrahydroi...)Show InChI InChI=1S/C10H10BrF2N/c11-8-2-1-6-4-9(10(12)13)14-5-7(6)3-8/h1-3,9-10,14H,4-5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| Article PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50072991
(7-Nitro-1,2,3,4-tetrahydro-isoquinoline | 7-nitro-...)Show InChI InChI=1S/C9H10N2O2/c12-11(13)9-2-1-7-3-4-10-6-8(7)5-9/h1-2,5,10H,3-4,6H2 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50072991
(7-Nitro-1,2,3,4-tetrahydro-isoquinoline | 7-nitro-...)Show InChI InChI=1S/C9H10N2O2/c12-11(13)9-2-1-7-3-4-10-6-8(7)5-9/h1-2,5,10H,3-4,6H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13026
(3-(fluoromethyl)-N-(2,2,2-trifluoroethyl)-1,2,3,4-...)Show InChI InChI=1S/C12H14F4N2O2S/c13-5-10-3-8-1-2-11(4-9(8)6-17-10)21(19,20)18-7-12(14,15)16/h1-2,4,10,17-18H,3,5-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 130 | -40.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13022
(3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-...)Show InChI InChI=1S/C10H13FN2O2S/c11-5-9-3-7-1-2-10(16(12,14)15)4-8(7)6-13-9/h1-2,4,9,13H,3,5-6H2,(H2,12,14,15) | PDB MMDB
Reactome pathway KEGG
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Similars
| Article PubMed
| 150 | -40.5 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50160906
((+/-)-3-difluoromethyl-7-nitro-1,2,3,4-tetrahydroi...)Show InChI InChI=1S/C10H10F2N2O2/c11-10(12)9-4-6-1-2-8(14(15)16)3-7(6)5-13-9/h1-3,9-10,13H,4-5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50186682
((+/-)-3-difluoromethyl-7-iodo-1,2,3,4-tetrahydrois...)Show InChI InChI=1S/C10H10F2IN/c11-10(12)9-4-6-1-2-8(13)3-7(6)5-14-9/h1-3,9-10,14H,4-5H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50199508
(7-bromo-1,2,3,4-tetrahydrobenzo[h]isoquinoline | C...)Show InChI InChI=1S/C13H12BrN/c14-13-3-1-2-10-11(13)5-4-9-6-7-15-8-12(9)10/h1-5,15H,6-8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13028
(3-(fluoromethyl)-N-(3,3,3-trifluoropropyl)-1,2,3,4...)Show InChI InChI=1S/C13H16F4N2O2S/c14-7-11-5-9-1-2-12(6-10(9)8-18-11)22(20,21)19-4-3-13(15,16)17/h1-2,6,11,18-19H,3-5,7-8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| 220 | -39.5 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50186670
((+/-)-3-difluoromethyl-7-(N-2,2,2-trifluoroethylam...)Show InChI InChI=1S/C12H13F5N2O2S/c13-11(14)10-4-7-1-2-9(3-8(7)5-18-10)22(20,21)19-6-12(15,16)17/h1-3,10-11,18-19H,4-6H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13024
(7-sulfonamide-THIQ 14 | CHEMBL290890 | N-(4-chloro...)Show InChI InChI=1S/C16H16ClFN2O2S/c17-13-2-4-14(5-3-13)20-23(21,22)16-6-1-11-7-15(9-18)19-10-12(11)8-16/h1-6,8,15,19-20H,7,9-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| Article PubMed
| 270 | -39.0 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13017
(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)Show InChI InChI=1S/C9H12N2O2S/c10-14(12,13)9-2-1-7-3-4-11-6-8(7)5-9/h1-2,5,11H,3-4,6H2,(H2,10,12,13) | PDB MMDB
Reactome pathway KEGG
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| DrugBank MMDB PDB Article PubMed
| 280 | -38.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13017
(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)Show InChI InChI=1S/C9H12N2O2S/c10-14(12,13)9-2-1-7-3-4-11-6-8(7)5-9/h1-2,5,11H,3-4,6H2,(H2,10,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank MMDB PDB Article PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM13017
(1,2,3,4-tetrahydroisoquinoline-7-sulfonamide | CHE...)Show InChI InChI=1S/C9H12N2O2S/c10-14(12,13)9-2-1-7-3-4-11-6-8(7)5-9/h1-2,5,11H,3-4,6H2,(H2,10,12,13) | PDB
UniProtKB/SwissProt
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| PDB Article PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50160902
(2-(7-Bromo-1,2,3,4-tetrahydro-isoquinolin-3-yl)-et...)Show InChI InChI=1S/C11H14BrNO/c12-10-2-1-8-6-11(3-4-14)13-7-9(8)5-10/h1-2,5,11,13-14H,3-4,6-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity against Human phenylethanolamine N-methyltransferase |
Bioorg Med Chem Lett 15: 1143-7 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.013 BindingDB Entry DOI: 10.7270/Q2X63MFG |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50227499
((S)-6-methyl-2-nitro-4,5,6,7-tetrahydrothieno[3,2-...)Show InChI InChI=1S/C8H10N2O2S/c1-5-2-7-6(4-9-5)3-8(13-7)10(11)12/h3,5,9H,2,4H2,1H3/t5-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of human PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50160904
(2-(7-Nitro-1,2,3,4-tetrahydro-isoquinolin-3-yl)-et...)Show InChI InChI=1S/C11H14N2O3/c14-4-3-10-5-8-1-2-11(13(15)16)6-9(8)7-12-10/h1-2,6,10,12,14H,3-5,7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity against Human phenylethanolamine N-methyltransferase |
Bioorg Med Chem Lett 15: 1143-7 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.013 BindingDB Entry DOI: 10.7270/Q2X63MFG |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50186677
((+/)-7-aminosulfonyl-3-difluoromethyl-1,2,3,4-tetr...)Show InChI InChI=1S/C10H12F2N2O2S/c11-10(12)9-4-6-1-2-8(17(13,15)16)3-7(6)5-14-9/h1-3,9-10,14H,4-5H2,(H2,13,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50227517
(2-bromo-6-methyl-4,5,6,7-tetrahydrothieno[3,2-c]py...)Show InChI InChI=1S/C8H10BrNS/c1-5-2-7-6(4-10-5)3-8(9)11-7/h3,5,10H,2,4H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 730 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of human PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13018
(7-methanesulfonyl-1,2,3,4-tetrahydroisoquinoline |...)Show InChI InChI=1S/C10H13NO2S/c1-14(12,13)10-3-2-8-4-5-11-7-9(8)6-10/h2-3,6,11H,4-5,7H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 790 | -36.2 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50186668
((+/-)-7-(N-4-chlorophenylaminosulfonyl)-3-difluoro...)Show SMILES FC(F)C1Cc2ccc(cc2CN1)S(=O)(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C16H15ClF2N2O2S/c17-12-2-4-13(5-3-12)21-24(22,23)14-6-1-10-8-15(16(18)19)20-9-11(10)7-14/h1-7,15-16,20-21H,8-9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
J Med Chem 49: 2939-52 (2006)
Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50199511
(7-nitro-1,2,3,4-tetrahydrobenzo[h]isoquinoline | C...)Show InChI InChI=1S/C13H12N2O2/c16-15(17)13-3-1-2-10-11(13)5-4-9-6-7-14-8-12(9)10/h1-5,14H,6-8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50199512
(1,2,3,4-tetrahydrobenzo[h]isoquinolin-7-ol | CHEMB...)Show InChI InChI=1S/C13H13NO/c15-13-3-1-2-10-11(13)5-4-9-6-7-14-8-12(9)10/h1-5,14-15H,6-8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13041
(3-(fluoromethyl)-7-methanesulfonyl-1,2,3,4-tetrahy...)Show InChI InChI=1S/C11H14FNO2S/c1-16(14,15)11-3-2-8-4-10(6-12)13-7-9(8)5-11/h2-3,5,10,13H,4,6-7H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10E+3 | -35.4 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50227502
(2-bromo-3a,4,5,6,7,7a-hexahydrothieno[3,2-c]pyridi...)Show InChI InChI=1S/C7H10BrNS/c8-7-3-5-4-9-2-1-6(5)10-7/h3,5-6,9H,1-2,4H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of human PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13034
(((+/-)-3-Fluoromethyl-7-(3,3,3-trifluoropropylsulf...)Show InChI InChI=1S/C13H15F4NO2S/c14-7-11-5-9-1-2-12(6-10(9)8-18-11)21(19,20)4-3-13(15,16)17/h1-2,6,11,18H,3-5,7-8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30E+3 | -34.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50160905
(3-(7-Nitro-1,2,3,4-tetrahydro-isoquinolin-3-yl)-pr...)Show InChI InChI=1S/C12H16N2O3/c15-5-1-2-11-6-9-3-4-12(14(16)17)7-10(9)8-13-11/h3-4,7,11,13,15H,1-2,5-6,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity against Human phenylethanolamine N-methyltransferase |
Bioorg Med Chem Lett 15: 1143-7 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.013 BindingDB Entry DOI: 10.7270/Q2X63MFG |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13030
(7-sulfonamide-THIQ 20 | CHEMBL177861 | N-ethyl-3-(...)Show InChI InChI=1S/C12H17FN2O2S/c1-2-15-18(16,17)12-4-3-9-5-11(7-13)14-8-10(9)6-12/h3-4,6,11,14-15H,2,5,7-8H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.40E+3 | -34.8 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13040
(3-(fluoromethyl)-7-[(2,2,2-trifluoroethane)sulfony...)Show InChI InChI=1S/C12H13F4NO2S/c13-5-10-3-8-1-2-11(4-9(8)6-17-10)20(18,19)7-12(14,15)16/h1-2,4,10,17H,3,5-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.40E+3 | -34.8 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50023304
(3-Methyl-1,2,3,4-tetrahydro-isoquinoline | 3-methy...)Show InChI InChI=1S/C10H13N/c1-8-6-9-4-2-3-5-10(9)7-11-8/h2-5,8,11H,6-7H2,1H3 | PDB
UniProtKB/SwissProt
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Patents
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| Article PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50072989
(1,2,3,4-Tetrahydro-isoquinoline-7-carbonitrile | 1...)Show InChI InChI=1S/C10H10N2/c11-6-8-1-2-9-3-4-12-7-10(9)5-8/h1-2,5,12H,3-4,7H2 | PDB MMDB
Reactome pathway KEGG
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Patents
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| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity to human PNMT |
Bioorg Med Chem 15: 1298-310 (2007)
Article DOI: 10.1016/j.bmc.2006.11.010 BindingDB Entry DOI: 10.7270/Q2HD7V9F |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50072989
(1,2,3,4-Tetrahydro-isoquinoline-7-carbonitrile | 1...)Show InChI InChI=1S/C10H10N2/c11-6-8-1-2-9-3-4-12-7-10(9)5-8/h1-2,5,12H,3-4,7H2 | PDB
UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Patents
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| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50077538
((R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)Show InChI InChI=1S/C10H12N2O2/c1-7-4-8-2-3-10(12(13)14)5-9(8)6-11-7/h2-3,5,7,11H,4,6H2,1H3/t7-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of human PNMT by radiochemical assay |
Bioorg Med Chem 16: 542-59 (2008)
Article DOI: 10.1016/j.bmc.2007.08.066 BindingDB Entry DOI: 10.7270/Q24B312R |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM13031
(3-(fluoromethyl)-N-propyl-1,2,3,4-tetrahydroisoqui...)Show InChI InChI=1S/C13H19FN2O2S/c1-2-5-16-19(17,18)13-4-3-10-6-12(8-14)15-9-11(10)7-13/h3-4,7,12,15-16H,2,5-6,8-9H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.70E+3 | -34.3 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Kansas
| Assay Description Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a... |
J Med Chem 49: 5424-33 (2006)
Article DOI: 10.1021/jm060466d BindingDB Entry DOI: 10.7270/Q2DB802Q |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50160903
(3-(7-Bromo-1,2,3,4-tetrahydro-isoquinolin-3-yl)-pr...)Show InChI InChI=1S/C12H16BrNO/c13-11-4-3-9-7-12(2-1-5-15)14-8-10(9)6-11/h3-4,6,12,14-15H,1-2,5,7-8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Binding affinity against Human phenylethanolamine N-methyltransferase |
Bioorg Med Chem Lett 15: 1143-7 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.013 BindingDB Entry DOI: 10.7270/Q2X63MFG |
More data for this Ligand-Target Pair | |