Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222258 ((Z)-4-(2-((E)-4-(2-chlorophenyl)-1-morpholino-2-ox...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM222262 ((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM222261 ((Z)-4-(2-((E)-4-(4-methoxyphenyl)-1-morpholino-2-o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222262 ((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222264 ((Z)-4-(2-((E)-4-(2-fluorophenyl)-1-morpholino-2-ox...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222259 ((Z)-4-(2-((E)-4-(2,4-dichlorophenyl)-1-morpholino-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM222263 ((Z)-4-(2-((E)-1-morpholino-2-oxo-4-(3,4,5-Trimetho...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222265 ((Z)-4-(2-((E)-4-(3-fluorophenyl)-1-morpholino-2-ox...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222267 ((Z)-4-(2-((E)-1-morpholino-4-(3-Nitrophenyl)-2-oxo...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222260 ((Z)-4-(2-((E)-4-(3-methoxyphenyl)-1-morpholino-2-o...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222266 ((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222261 ((Z)-4-(2-((E)-4-(4-methoxyphenyl)-1-morpholino-2-o...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.71E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM222263 ((Z)-4-(2-((E)-1-morpholino-2-oxo-4-(3,4,5-Trimetho...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.75E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM222263 ((Z)-4-(2-((E)-1-morpholino-2-oxo-4-(3,4,5-Trimetho...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM222259 ((Z)-4-(2-((E)-4-(2,4-dichlorophenyl)-1-morpholino-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM222266 ((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM222259 ((Z)-4-(2-((E)-4-(2,4-dichlorophenyl)-1-morpholino-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.32E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM222261 ((Z)-4-(2-((E)-4-(4-methoxyphenyl)-1-morpholino-2-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.42E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM222258 ((Z)-4-(2-((E)-4-(2-chlorophenyl)-1-morpholino-2-ox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.43E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM222262 ((Z)-4-(2-((E)-4-(3,4-dimethoxyphenyl)-1-morpholino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.41E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM222258 ((Z)-4-(2-((E)-4-(2-chlorophenyl)-1-morpholino-2-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle)) | BDBM50241179 ((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.02E+4 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM222266 ((Z)-4-(2-((E)-4-(2-bromophenyl)-1-morpholino-2-oxo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.24E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.21E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-nucleotidase (Rattus norvegicus (Rat)) | BDBM26994 (CHEMBL68253 | H2NSO3H | sulfamic acid) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.73E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
COMSATS Institute of Information Technology | Assay Description The ecto-5'-nucleotidase inhibition assay was performed according to our previously reported protocol [Raza et al., Med. Chem., 8:1133-1139]. The com... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal-type alkaline phosphatase (Bos taurus (Cattle)) | BDBM18073 ((2S)-2-amino-3-phenylpropanoic acid | CHEMBL301523...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.02E+4 | n/a | n/a | n/a | n/a | 9.8 | 37 |
COMSATS Institute of Information Technology | Assay Description Alkaline phosphatase assay was optimized and performed in the same way as previously reported method with slight modifications [Sergienko et al., Nat... | Bioorg Chem 70: 229-236 (2017) Article DOI: 10.1016/j.bioorg.2017.01.003 BindingDB Entry DOI: 10.7270/Q2K07334 | |||||||||||
More data for this Ligand-Target Pair |