Compile Data Set for Download or QSAR

Found 172 hits with Last Name = 'slaughter' and Initial = 'rs'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125504 (CHEMBL16806 | Methyl-carbamic acid 4-[(2-methoxy-b...) Show SMILES CNC(=O)O[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1 |wU:8.8,wD:5.4,(-6.12,-5.94,;-4.77,-5.17,;-3.45,-5.96,;-3.47,-7.5,;-2.11,-5.2,;-2.1,-3.66,;-.77,-2.89,;-.77,-1.35,;-2.1,-.58,;-.77,.19,;.57,-.58,;1.89,.19,;1.89,1.72,;3.24,-.58,;3.24,-2.13,;4.55,-2.89,;5.9,-2.13,;5.9,-.58,;4.55,.19,;4.55,1.72,;3.24,2.49,;-3.44,-1.35,;-3.44,-2.89,;-3.44,.19,;-3.44,1.72,;-4.76,2.49,;-6.1,1.72,;-6.1,.19,;-4.77,-.58,)| Show InChI InChI=1S/C23H28N2O4/c1-24-22(27)29-18-12-14-23(15-13-18,17-8-4-3-5-9-17)16-25-21(26)19-10-6-7-11-20(19)28-2/h3-11,18H,12-16H2,1-2H3,(H,24,27)(H,25,26)/t18-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DiTc binding to Kv1.3 channel in human brain membranes				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125521 (CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...) Show SMILES CCCNC(=O)O[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1 |wU:10.10,wD:7.6,(-9.05,-5.79,;-9.05,-7.33,;-7.74,-8.13,;-6.39,-7.36,;-5.06,-8.15,;-5.08,-9.69,;-3.7,-7.4,;-3.7,-5.86,;-2.37,-5.09,;-2.37,-3.53,;-3.7,-2.76,;-2.37,-1.99,;-1.02,-2.76,;.31,-1.99,;.31,-.45,;1.64,-2.76,;1.64,-4.32,;2.97,-5.09,;4.32,-4.32,;4.32,-2.76,;2.97,-1.99,;2.97,-.45,;1.64,.32,;-5.03,-3.53,;-5.03,-5.09,;-5.03,-1.99,;-6.39,-2.76,;-7.72,-1.99,;-7.72,-.45,;-6.36,.32,;-5.03,-.45,)| Show InChI InChI=1S/C25H32N2O4/c1-3-17-26-24(29)31-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(28)21-11-7-8-12-22(21)30-2/h4-12,20H,3,13-18H2,1-2H3,(H,26,29)(H,27,28)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DiTc binding to Kv1.3 channel in human brain membranes				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158202 (CHEMBL434526 | Correloid derivative) Show SMILES COC(=O)C12O[C@@H]1C(=C)C[C@@]1(O)C3CC[C@@]4(C)C5C=CCOC[C@]5([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C4[C@@]3(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@]21C |c:19| Show InChI InChI=1S/C40H54O15/c1-19-17-39(47)27-14-15-35(8)26-13-12-16-49-18-38(26,20(2)50-21(3)41)31(52-23(5)43)28(51-22(4)42)29(35)36(27,9)32(53-24(6)44)33(54-25(7)45)37(39,10)40(30(19)55-40)34(46)48-11/h12-13,20,26-33,47H,1,14-18H2,2-11H3/t20-,26?,27?,28+,29?,30-,31+,32-,33+,35+,36+,37-,38-,39-,40?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158200 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H54O11/c1-23(30-14-11-12-15-31(30)47-10)21-41(46)24(2)20-34(50-27(5)43)39(9)33(41)17-18-38(8)32-16-13-19-48-22-40(32,25(3)49-26(4)42)37(52-29(7)45)35(36(38)39)51-28(6)44/h11-16,20,25,32-37,46H,1,17-19,21-22H2,2-10H3/t25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158214 (Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@H](CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C)c1ccccc1 |c:11,44| Show InChI InChI=1S/C40H54O10/c1-23(30-14-11-10-12-15-30)21-40(45)24(2)20-33(48-27(5)42)38(9)32(40)17-18-37(8)31-16-13-19-46-22-39(31,25(3)47-26(4)41)36(50-29(7)44)34(35(37)38)49-28(6)43/h10-16,20,23,25,31-36,45H,17-19,21-22H2,1-9H3/t23-,25-,31?,32?,33-,34+,35?,36+,37+,38-,39-,40?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158213 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CC[C@H](CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C)c1ccccc1CC |c:12,45| Show InChI InChI=1S/C43H60O10/c1-11-31-16-13-14-17-33(31)32(12-2)23-43(48)25(3)22-36(51-28(6)45)41(10)35(43)19-20-40(9)34-18-15-21-49-24-42(34,26(4)50-27(5)44)39(53-30(8)47)37(38(40)41)52-29(7)46/h13-18,22,26,32,34-39,48H,11-12,19-21,23-24H2,1-10H3/t26-,32-,34?,35?,36-,37+,38?,39+,40+,41-,42-,43?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158218 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCOc1ccccc1[C@H](C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:21,54| Show InChI InChI=1S/C42H58O11/c1-11-49-32-16-13-12-15-31(32)24(2)22-42(47)25(3)21-35(51-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)50-27(5)43)38(53-30(8)46)36(37(39)40)52-29(7)45/h12-17,21,24,26,33-38,47H,11,18-20,22-23H2,1-10H3/t24-,26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158224 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1CCC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:19,52| Show InChI InChI=1S/C40H54O11/c1-23-21-33(49-26(4)42)38(8)32(40(23,45)19-16-29-13-10-11-14-30(29)46-9)17-18-37(7)31-15-12-20-47-22-39(31,24(2)48-25(3)41)36(51-28(6)44)34(35(37)38)50-27(5)43/h10-15,21,24,31-36,45H,16-20,22H2,1-9H3/t24-,31?,32?,33-,34+,35?,36+,37+,38-,39-,40?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158233 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CSc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H54O10S/c1-23(30-14-11-12-15-31(30)52-10)21-41(46)24(2)20-34(49-27(5)43)39(9)33(41)17-18-38(8)32-16-13-19-47-22-40(32,25(3)48-26(4)42)37(51-29(7)45)35(36(38)39)50-28(6)44/h11-16,20,25,32-37,46H,1,17-19,21-22H2,2-10H3/t25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158233 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CSc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H54O10S/c1-23(30-14-11-12-15-31(30)52-10)21-41(46)24(2)20-34(49-27(5)43)39(9)33(41)17-18-38(8)32-16-13-19-47-22-40(32,25(3)48-26(4)42)37(51-29(7)45)35(36(38)39)50-28(6)44/h11-16,20,25,32-37,46H,1,17-19,21-22H2,2-10H3/t25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158228 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCSc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:21,54| Show InChI InChI=1S/C42H56O10S/c1-11-53-32-16-13-12-15-31(32)24(2)22-42(47)25(3)21-35(50-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)49-27(5)43)38(52-30(8)46)36(37(39)40)51-29(7)45/h12-17,21,26,33-38,47H,2,11,18-20,22-23H2,1,3-10H3/t26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125498 (Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...) Show SMILES COc1ccccc1C(=O)NC[C@]1(CC[C@@H](CC1)OC(=O)NCC=C)c1ccccc1 |wU:12.12,wD:15.19,(3.96,3.63,;5.29,2.86,;5.29,1.32,;6.63,.55,;6.63,-1.01,;5.29,-1.78,;3.96,-1.01,;3.96,.55,;2.62,1.32,;2.62,2.86,;1.29,.55,;-.05,1.32,;-1.38,.55,;-.05,-.22,;-.05,-1.78,;-1.38,-2.55,;-2.7,-1.78,;-2.7,-.22,;-1.39,-4.09,;-2.73,-4.83,;-2.75,-6.37,;-4.06,-4.04,;-5.41,-4.81,;-6.73,-4.02,;-8.08,-4.79,;-2.72,1.32,;-4.06,.55,;-5.39,1.32,;-5.39,2.86,;-4.05,3.63,;-2.72,2.86,)| Show InChI InChI=1S/C25H30N2O4/c1-3-17-26-24(29)31-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(28)21-11-7-8-12-22(21)30-2/h3-12,20H,1,13-18H2,2H3,(H,26,29)(H,27,28)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158195 (Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CC(C)(C)c4ccccc4)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,33| Show InChI InChI=1S/C41H56O10/c1-24-21-33(49-27(4)43)39(10)32(41(24,46)22-37(7,8)30-15-12-11-13-16-30)18-19-38(9)31-17-14-20-47-23-40(31,25(2)48-26(3)42)36(51-29(6)45)34(35(38)39)50-28(5)44/h11-17,21,25,31-36,46H,18-20,22-23H2,1-10H3/t25-,31?,32?,33-,34+,35?,36+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158227 (Aceticacid1-[4,5,6-triacetoxy-1-hydroxy-2,4a,11b-t...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3[C@](O)(CC(=C)c4ccccc4)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,32| Show InChI InChI=1S/C40H52O10/c1-23(30-14-11-10-12-15-30)21-40(45)24(2)20-33(48-27(5)42)38(9)32(40)17-18-37(8)31-16-13-19-46-22-39(31,25(3)47-26(4)41)36(50-29(7)44)34(35(37)38)49-28(6)43/h10-16,20,25,31-36,45H,1,17-19,21-22H2,2-9H3/t25-,31?,32?,33-,34+,35?,36+,37+,38-,39-,40+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158210 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1[C@H](C)C[C@@]1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H56O11/c1-23(30-14-11-12-15-31(30)47-10)21-41(46)24(2)20-34(50-27(5)43)39(9)33(41)17-18-38(8)32-16-13-19-48-22-40(32,25(3)49-26(4)42)37(52-29(7)45)35(36(38)39)51-28(6)44/h11-16,20,23,25,32-37,46H,17-19,21-22H2,1-10H3/t23-,25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158209 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1[C@H](CC=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:22,55| Show InChI InChI=1S/C43H58O11/c1-11-15-31(32-16-12-13-17-33(32)49-10)23-43(48)25(2)22-36(52-28(5)45)41(9)35(43)19-20-40(8)34-18-14-21-50-24-42(34,26(3)51-27(4)44)39(54-30(7)47)37(38(40)41)53-29(6)46/h11-14,16-18,22,26,31,34-39,48H,1,15,19-21,23-24H2,2-10H3/t26-,31-,34?,35?,36-,37+,38?,39+,40+,41-,42-,43?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158226 (Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES [#6]-[#6@@H](-[#8]-[#6](-[#6])=O)[C@]12[#6]-[#8]-[#6]-[#6]=[#6]-[#6]1[C@]1([#6])[#6]-[#6]-[#6]3C([#8])([#6]-[#6]\[#6]=[#6](\[#6])-[#6])[#6](-[#6])=[#6]-[#6@@H](-[#8]-[#6](-[#6])=O)[C@]3([#6])[#6]1-[#6@H](-[#8]-[#6](-[#6])=O)-[#6@@H]2-[#8]-[#6](-[#6])=O |c:10,28| Show InChI InChI=1S/C37H54O10/c1-21(2)13-11-16-37(42)22(3)19-30(45-25(6)39)35(10)29(37)15-17-34(9)28-14-12-18-43-20-36(28,23(4)44-24(5)38)33(47-27(8)41)31(32(34)35)46-26(7)40/h12-14,19,23,28-33,42H,11,15-18,20H2,1-10H3/t23-,28?,29?,30-,31+,32?,33+,34+,35-,36-,37?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158197 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1cccc(CCC2(O)C3CC[C@@]4(C)C5C=CCOC[C@]5([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C4[C@@]3(C)[C@H](OC(C)=O)C=C2C)c1 |c:17,50| Show InChI InChI=1S/C40H54O11/c1-23-20-33(49-26(4)42)38(8)32(40(23,45)18-15-29-12-10-13-30(21-29)46-9)16-17-37(7)31-14-11-19-47-22-39(31,24(2)48-25(3)41)36(51-28(6)44)34(35(37)38)50-27(5)43/h10-14,20-21,24,31-36,45H,15-19,22H2,1-9H3/t24-,31?,32?,33-,34+,35?,36+,37+,38-,39-,40?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158217 (Aceticacid1-{(R)-4,5,6-triacetoxy-1-[2-(2-ethyl-ph...) Show SMILES CCc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C42H56O10/c1-11-31-15-12-13-16-32(31)24(2)22-42(47)25(3)21-35(50-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)49-27(5)43)38(52-30(8)46)36(37(39)40)51-29(7)45/h12-17,21,26,33-38,47H,2,11,18-20,22-23H2,1,3-10H3/t26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158210 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1[C@H](C)C[C@@]1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H56O11/c1-23(30-14-11-12-15-31(30)47-10)21-41(46)24(2)20-34(50-27(5)43)39(9)33(41)17-18-38(8)32-16-13-19-48-22-40(32,25(3)49-26(4)42)37(52-29(7)45)35(36(38)39)51-28(6)44/h11-16,20,23,25,32-37,46H,17-19,21-22H2,1-10H3/t23-,25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158215 (Aceticacid(R)-1-((4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CCc4ccccc4)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,31| Show InChI InChI=1S/C39H52O10/c1-23-21-32(47-26(4)41)37(8)31(39(23,44)19-16-29-13-10-9-11-14-29)17-18-36(7)30-15-12-20-45-22-38(30,24(2)46-25(3)40)35(49-28(6)43)33(34(36)37)48-27(5)42/h9-15,21,24,30-35,44H,16-20,22H2,1-8H3/t24-,30?,31?,32-,33+,34?,35+,36+,37-,38-,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158211 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CCc4ccccc4O)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,32| Show InChI InChI=1S/C39H52O11/c1-22-20-32(48-25(4)41)37(8)31(39(22,45)18-15-28-12-9-10-13-29(28)44)16-17-36(7)30-14-11-19-46-21-38(30,23(2)47-24(3)40)35(50-27(6)43)33(34(36)37)49-26(5)42/h9-14,20,23,30-35,44-45H,15-19,21H2,1-8H3/t23-,30?,31?,32-,33+,34?,35+,36+,37-,38-,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158216 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CC[C@H](CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C)c1ccccc1OC |c:12,45| Show InChI InChI=1S/C42H58O11/c1-11-30(31-15-12-13-16-32(31)48-10)22-42(47)24(2)21-35(51-27(5)44)40(9)34(42)18-19-39(8)33-17-14-20-49-23-41(33,25(3)50-26(4)43)38(53-29(7)46)36(37(39)40)52-28(6)45/h12-17,21,25,30,33-38,47H,11,18-20,22-23H2,1-10H3/t25-,30-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158206 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCc1ccccc1[C@H](C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C42H58O10/c1-11-31-15-12-13-16-32(31)24(2)22-42(47)25(3)21-35(50-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)49-27(5)43)38(52-30(8)46)36(37(39)40)51-29(7)45/h12-17,21,24,26,33-38,47H,11,18-20,22-23H2,1-10H3/t24-,26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125501 (CHEMBL16255 | N-[4-(3-Allyl-ureido)-1-phenyl-cyclo...) Show SMILES COc1ccccc1C(=O)NC[C@]1(CC[C@@H](CC1)NC(=O)NCC=C)c1ccccc1 |wU:12.12,wD:15.19,(2.5,-.08,;3.83,-.85,;3.83,-2.39,;5.18,-3.16,;5.18,-4.71,;3.83,-5.48,;2.5,-4.71,;2.5,-3.16,;1.15,-2.39,;1.15,-.85,;-.18,-3.16,;-1.52,-2.39,;-2.85,-3.16,;-1.52,-3.94,;-1.52,-5.48,;-2.85,-6.25,;-4.19,-5.48,;-4.19,-3.94,;-2.85,-7.79,;-1.52,-8.57,;-.19,-7.79,;-1.52,-10.11,;-.19,-10.88,;1.15,-10.11,;2.48,-10.88,;-3.97,-2.07,;-5.42,-2.49,;-6.52,-1.39,;-6.13,.09,;-4.68,.51,;-3.58,-.59,)| Show InChI InChI=1S/C25H31N3O3/c1-3-17-26-24(30)28-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(29)21-11-7-8-12-22(21)31-2/h3-12,20H,1,13-18H2,2H3,(H,27,29)(H2,26,28,30)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DiTc binding to Kv1.3 channel in human brain membranes				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158216 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CC[C@H](CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C)c1ccccc1OC |c:12,45| Show InChI InChI=1S/C42H58O11/c1-11-30(31-15-12-13-16-32(31)48-10)22-42(47)24(2)21-35(51-27(5)44)40(9)34(42)18-19-39(8)33-17-14-20-49-23-41(33,25(3)50-26(4)43)38(53-29(7)46)36(37(39)40)52-28(6)45/h12-17,21,25,30,33-38,47H,11,18-20,22-23H2,1-10H3/t25-,30-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29.2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158223 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CCc4ccccc4OC(C)=O)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,35| Show InChI InChI=1S/C41H54O12/c1-23-21-34(51-27(5)44)39(9)33(41(23,47)19-16-30-13-10-11-14-31(30)50-26(4)43)17-18-38(8)32-15-12-20-48-22-40(32,24(2)49-25(3)42)37(53-29(7)46)35(36(38)39)52-28(6)45/h10-15,21,24,32-37,47H,16-20,22H2,1-9H3/t24-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158228 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCSc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:21,54| Show InChI InChI=1S/C42H56O10S/c1-11-53-32-16-13-12-15-31(32)24(2)22-42(47)25(3)21-35(50-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)49-27(5)43)38(52-30(8)46)36(37(39)40)51-29(7)45/h12-17,21,26,33-38,47H,2,11,18-20,22-23H2,1,3-10H3/t26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158209 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1[C@H](CC=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:22,55| Show InChI InChI=1S/C43H58O11/c1-11-15-31(32-16-12-13-17-33(32)49-10)23-43(48)25(2)22-36(52-28(5)45)41(9)35(43)19-20-40(8)34-18-14-21-50-24-42(34,26(3)51-27(4)44)39(54-30(7)47)37(38(40)41)53-29(6)46/h11-14,16-18,22,26,31,34-39,48H,1,15,19-21,23-24H2,2-10H3/t26-,31-,34?,35?,36-,37+,38?,39+,40+,41-,42-,43?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32.9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158207 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCOc1ccccc1CCC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H56O11/c1-10-48-31-15-12-11-14-30(31)17-20-41(46)24(2)22-34(50-27(5)43)39(9)33(41)18-19-38(8)32-16-13-21-47-23-40(32,25(3)49-26(4)42)37(52-29(7)45)35(36(38)39)51-28(6)44/h11-16,22,25,32-37,46H,10,17-21,23H2,1-9H3/t25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158230 (CHEMBL362199 | Correloid derivative) Show SMILES COC(=O)C12O[C@@H]1C(=O)CC1(O)C3CC[C@@]4(C)C5C=CCOC[C@]5([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C4[C@@]3(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@]21C |c:19| Show InChI InChI=1S/C39H52O16/c1-18(50-19(2)40)37-17-49-15-11-12-25(37)34(7)14-13-26-35(8,28(34)27(51-20(3)41)30(37)52-21(4)42)31(53-22(5)43)32(54-23(6)44)36(9)38(26,47)16-24(45)29-39(36,55-29)33(46)48-10/h11-12,18,25-32,47H,13-17H2,1-10H3/t18-,25?,26?,27+,28?,29-,30+,31-,32+,34+,35+,36-,37-,38?,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158206 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCc1ccccc1[C@H](C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C42H58O10/c1-11-31-15-12-13-16-32(31)24(2)22-42(47)25(3)21-35(50-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)49-27(5)43)38(52-30(8)46)36(37(39)40)51-29(7)45/h12-17,21,24,26,33-38,47H,11,18-20,22-23H2,1-10H3/t24-,26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36.8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158218 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCOc1ccccc1[C@H](C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:21,54| Show InChI InChI=1S/C42H58O11/c1-11-49-32-16-13-12-15-31(32)24(2)22-42(47)25(3)21-35(51-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)50-27(5)43)38(53-30(8)46)36(37(39)40)52-29(7)45/h12-17,21,24,26,33-38,47H,11,18-20,22-23H2,1-10H3/t24-,26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158220 (Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CCc4ccccc4C)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,32| Show InChI InChI=1S/C40H54O10/c1-23-13-10-11-14-30(23)16-19-40(45)24(2)21-33(48-27(5)42)38(9)32(40)17-18-37(8)31-15-12-20-46-22-39(31,25(3)47-26(4)41)36(50-29(7)44)34(35(37)38)49-28(6)43/h10-15,21,25,31-36,45H,16-20,22H2,1-9H3/t25-,31?,32?,33-,34+,35?,36+,37+,38-,39-,40?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158217 (Aceticacid1-{(R)-4,5,6-triacetoxy-1-[2-(2-ethyl-ph...) Show SMILES CCc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C42H56O10/c1-11-31-15-12-13-16-32(31)24(2)22-42(47)25(3)21-35(50-28(6)44)40(10)34(42)18-19-39(9)33-17-14-20-48-23-41(33,26(4)49-27(5)43)38(52-30(8)46)36(37(39)40)51-29(7)45/h12-17,21,26,33-38,47H,2,11,18-20,22-23H2,1,3-10H3/t26-,33?,34?,35-,36+,37?,38+,39+,40-,41-,42?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125509 (Allyl-carbamic acid 4-[(5-fluoro-2-methoxy-benzoyl...) Show SMILES COc1ccc(F)cc1C(=O)NC[C@]1(CC[C@@H](CC1)OC(=O)NCC=C)c1ccccc1 |wU:13.13,wD:16.20,(2.06,.16,;3.38,-.59,;3.38,-2.14,;4.71,-2.91,;4.71,-4.45,;3.38,-5.22,;3.36,-6.76,;2.05,-4.45,;2.05,-2.91,;.71,-2.14,;.71,-.59,;-.62,-2.91,;-1.95,-2.14,;-3.28,-2.91,;-1.95,-3.68,;-1.95,-5.22,;-3.28,-5.99,;-4.61,-5.22,;-4.61,-3.68,;-3.28,-7.53,;-1.96,-8.3,;-.63,-7.53,;-1.96,-9.83,;-3.28,-10.6,;-4.62,-9.83,;-5.95,-10.6,;-4.39,-1.82,;-5.84,-2.22,;-6.93,-1.15,;-6.53,.32,;-5.09,.74,;-4,-.33,)| Show InChI InChI=1S/C25H29FN2O4/c1-3-15-27-24(30)32-20-11-13-25(14-12-20,18-7-5-4-6-8-18)17-28-23(29)21-16-19(26)9-10-22(21)31-2/h3-10,16,20H,1,11-15,17H2,2H3,(H,27,30)(H,28,29)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158198 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCc1ccccc1[C@H](CC=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:22,55| Show InChI InChI=1S/C44H60O10/c1-11-16-33(34-18-14-13-17-32(34)12-2)24-44(49)26(3)23-37(52-29(6)46)42(10)36(44)20-21-41(9)35-19-15-22-50-25-43(35,27(4)51-28(5)45)40(54-31(8)48)38(39(41)42)53-30(7)47/h11,13-15,17-19,23,27,33,35-40,49H,1,12,16,20-22,24-25H2,2-10H3/t27-,33-,35?,36?,37-,38+,39?,40+,41+,42-,43-,44?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125521 (CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...) Show SMILES CCCNC(=O)O[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1 |wU:10.10,wD:7.6,(-9.05,-5.79,;-9.05,-7.33,;-7.74,-8.13,;-6.39,-7.36,;-5.06,-8.15,;-5.08,-9.69,;-3.7,-7.4,;-3.7,-5.86,;-2.37,-5.09,;-2.37,-3.53,;-3.7,-2.76,;-2.37,-1.99,;-1.02,-2.76,;.31,-1.99,;.31,-.45,;1.64,-2.76,;1.64,-4.32,;2.97,-5.09,;4.32,-4.32,;4.32,-2.76,;2.97,-1.99,;2.97,-.45,;1.64,.32,;-5.03,-3.53,;-5.03,-5.09,;-5.03,-1.99,;-6.39,-2.76,;-7.72,-1.99,;-7.72,-.45,;-6.36,.32,;-5.03,-.45,)| Show InChI InChI=1S/C25H32N2O4/c1-3-17-26-24(29)31-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(28)21-11-7-8-12-22(21)30-2/h4-12,20H,3,13-18H2,1-2H3,(H,26,29)(H,27,28)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158200 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES COc1ccccc1C(=C)CC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H54O11/c1-23(30-14-11-12-15-31(30)47-10)21-41(46)24(2)20-34(50-27(5)43)39(9)33(41)17-18-38(8)32-16-13-19-48-22-40(32,25(3)49-26(4)42)37(52-29(7)45)35(36(38)39)51-28(6)44/h11-16,20,25,32-37,46H,1,17-19,21-22H2,2-10H3/t25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51.1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125504 (CHEMBL16806 | Methyl-carbamic acid 4-[(2-methoxy-b...) Show SMILES CNC(=O)O[C@H]1CC[C@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1 |wU:8.8,wD:5.4,(-6.12,-5.94,;-4.77,-5.17,;-3.45,-5.96,;-3.47,-7.5,;-2.11,-5.2,;-2.1,-3.66,;-.77,-2.89,;-.77,-1.35,;-2.1,-.58,;-.77,.19,;.57,-.58,;1.89,.19,;1.89,1.72,;3.24,-.58,;3.24,-2.13,;4.55,-2.89,;5.9,-2.13,;5.9,-.58,;4.55,.19,;4.55,1.72,;3.24,2.49,;-3.44,-1.35,;-3.44,-2.89,;-3.44,.19,;-3.44,1.72,;-4.76,2.49,;-6.1,1.72,;-6.1,.19,;-4.77,-.58,)| Show InChI InChI=1S/C23H28N2O4/c1-24-22(27)29-18-12-14-23(15-13-18,17-8-4-3-5-9-17)16-25-21(26)19-10-6-7-11-20(19)28-2/h3-11,18H,12-16H2,1-2H3,(H,24,27)(H,25,26)/t18-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125498 (Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...) Show SMILES COc1ccccc1C(=O)NC[C@]1(CC[C@@H](CC1)OC(=O)NCC=C)c1ccccc1 |wU:12.12,wD:15.19,(3.96,3.63,;5.29,2.86,;5.29,1.32,;6.63,.55,;6.63,-1.01,;5.29,-1.78,;3.96,-1.01,;3.96,.55,;2.62,1.32,;2.62,2.86,;1.29,.55,;-.05,1.32,;-1.38,.55,;-.05,-.22,;-.05,-1.78,;-1.38,-2.55,;-2.7,-1.78,;-2.7,-.22,;-1.39,-4.09,;-2.73,-4.83,;-2.75,-6.37,;-4.06,-4.04,;-5.41,-4.81,;-6.73,-4.02,;-8.08,-4.79,;-2.72,1.32,;-4.06,.55,;-5.39,1.32,;-5.39,2.86,;-4.05,3.63,;-2.72,2.86,)| Show InChI InChI=1S/C25H30N2O4/c1-3-17-26-24(29)31-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(28)21-11-7-8-12-22(21)30-2/h3-12,20H,1,13-18H2,2H3,(H,26,29)(H,27,28)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125513 (CHEMBL277598 | {4-[(2-Methoxy-benzoylamino)-methyl...) Show SMILES COc1ccccc1C(=O)NC[C@@]1(CC[C@@H](CC1)NC(=O)OCC=C)c1ccccc1 |wU:12.12,15.19,(12.7,1.28,;14.04,.51,;14.04,-1.04,;15.37,-1.81,;15.37,-3.35,;14.04,-4.12,;12.7,-3.35,;12.7,-1.81,;11.35,-1.04,;11.35,.53,;10.02,-1.81,;8.68,-1.04,;7.35,-1.81,;6.02,-2.58,;6.02,-4.12,;7.35,-4.89,;8.68,-4.12,;8.68,-2.58,;7.35,-6.44,;8.68,-7.21,;10.02,-6.44,;8.68,-8.75,;10.02,-9.52,;10.02,-11.07,;11.35,-11.84,;6.23,-.71,;6.62,.76,;5.53,1.86,;4.07,1.44,;3.68,-.03,;4.77,-1.13,)| Show InChI InChI=1S/C25H30N2O4/c1-3-17-31-24(29)27-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-26-23(28)21-11-7-8-12-22(21)30-2/h3-12,20H,1,13-18H2,2H3,(H,26,28)(H,27,29)/t20-,25-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of T-cell proliferation was determined by a human T-cell assay				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158196 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CCc4ccccc4F)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,32| Show InChI InChI=1S/C39H51FO10/c1-22-20-32(48-25(4)42)37(8)31(39(22,45)18-15-28-12-9-10-13-29(28)40)16-17-36(7)30-14-11-19-46-21-38(30,23(2)47-24(3)41)35(50-27(6)44)33(34(36)37)49-26(5)43/h9-14,20,23,30-35,45H,15-19,21H2,1-8H3/t23-,30?,31?,32-,33+,34?,35+,36+,37-,38-,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125531 (CHEMBL16848 | Isopropyl-carbamic acid 4-[(2-methox...) Show SMILES COc1ccccc1C(=O)NC[C@]1(CC[C@@H](CC1)OC(=O)NC(C)C)c1ccccc1 |wU:12.12,wD:15.19,(1.14,2.86,;2.47,2.09,;2.47,.55,;3.81,-.22,;3.81,-1.77,;2.47,-2.54,;1.14,-1.77,;1.14,-.22,;-.2,.55,;-.2,2.09,;-1.53,-.22,;-2.87,.55,;-4.2,-.22,;-2.87,-.99,;-2.87,-2.54,;-4.2,-3.31,;-5.53,-2.54,;-5.53,-.99,;-4.21,-4.85,;-5.55,-5.6,;-5.57,-7.14,;-6.88,-4.81,;-8.23,-5.58,;-9.55,-4.79,;-8.25,-7.12,;-5.54,.55,;-6.88,-.22,;-8.22,.55,;-8.22,2.09,;-6.87,2.86,;-5.54,2.09,)| Show InChI InChI=1S/C25H32N2O4/c1-18(2)27-24(29)31-20-13-15-25(16-14-20,19-9-5-4-6-10-19)17-26-23(28)21-11-7-8-12-22(21)30-3/h4-12,18,20H,13-17H2,1-3H3,(H,26,28)(H,27,29)/t20-,25+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125512 (CHEMBL16468 | N-(4-Benzoylamino-1-phenyl-cyclohexy...) Show SMILES COc1ccccc1C(=O)NC[C@@]1(CC[C@@H](CC1)NC(=O)c1ccccc1)c1ccccc1 |wU:12.12,15.19,(.54,3.3,;1.87,2.53,;1.87,.98,;3.2,.21,;3.2,-1.33,;1.87,-2.1,;.54,-1.33,;.54,.21,;-.82,.98,;-.82,2.55,;-2.15,.21,;-3.48,.98,;-4.82,.21,;-6.15,-.56,;-6.15,-2.1,;-4.82,-2.88,;-3.48,-2.1,;-3.48,-.56,;-4.82,-4.42,;-3.48,-5.19,;-2.15,-4.42,;-3.48,-6.73,;-4.84,-7.49,;-4.84,-9.05,;-3.48,-9.82,;-2.15,-9.05,;-2.15,-7.49,;-5.94,1.31,;-5.54,2.78,;-6.64,3.9,;-8.11,3.46,;-8.49,1.99,;-7.4,.89,)| Show InChI InChI=1S/C28H30N2O3/c1-33-25-15-9-8-14-24(25)27(32)29-20-28(22-12-6-3-7-13-22)18-16-23(17-19-28)30-26(31)21-10-4-2-5-11-21/h2-15,23H,16-20H2,1H3,(H,29,32)(H,30,31)/t23-,28-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125516 (CHEMBL279606 | Propyl-carbamic acid 4-[(2-methoxy-...) Show SMILES CCCNC(=O)O[C@H]1CC[C@@](CNC(=O)c2ccccc2OC)(CC1)c1ccccc1 |wU:10.10,7.6,(-3.03,-11.46,;-1.71,-10.69,;-1.72,-9.15,;-3.06,-8.38,;-3.06,-6.83,;-1.72,-6.06,;-4.39,-6.06,;-4.39,-4.51,;-5.72,-3.74,;-5.72,-2.18,;-4.39,-1.41,;-3.06,-.64,;-1.71,-1.41,;-.37,-.64,;-.37,.9,;.97,-1.41,;.97,-2.97,;2.3,-3.74,;3.65,-2.97,;3.65,-1.41,;2.3,-.64,;2.3,.9,;.97,1.68,;-3.06,-2.18,;-3.06,-3.74,;-5.49,-.33,;-6.96,-.73,;-8.04,.35,;-7.66,1.82,;-6.21,2.24,;-5.11,1.16,)| Show InChI InChI=1S/C25H32N2O4/c1-3-17-26-24(29)31-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(28)21-11-7-8-12-22(21)30-2/h4-12,20H,3,13-18H2,1-2H3,(H,26,29)(H,27,28)/t20-,25-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of T-cell proliferation was determined by a human T-cell assay				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158207 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES CCOc1ccccc1CCC1(O)C2CC[C@@]3(C)C4C=CCOC[C@]4([C@@H](C)OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)C3[C@@]2(C)[C@H](OC(C)=O)C=C1C |c:20,53| Show InChI InChI=1S/C41H56O11/c1-10-48-31-15-12-11-14-30(31)17-20-41(46)24(2)22-34(50-27(5)43)39(9)33(41)18-19-38(8)32-16-13-21-47-23-40(32,25(3)49-26(4)42)37(52-29(7)45)35(36(38)39)51-28(6)44/h11-16,22,25,32-37,46H,10,17-21,23H2,1-9H3/t25-,32?,33?,34-,35+,36?,37+,38+,39-,40-,41?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125526 (CHEMBL16683 | N-[4-(3-Allyl-ureido)-1-phenyl-cyclo...) Show SMILES COc1ccccc1C(=O)NC[C@@]1(CC[C@@H](CC1)NC(=O)NCC=C)c1ccccc1 |wU:12.12,15.19,(11.14,1.75,;12.47,.97,;12.47,-.57,;13.8,-1.34,;13.8,-2.88,;12.47,-3.66,;11.14,-2.88,;11.14,-1.34,;9.78,-.57,;9.78,1,;8.45,-1.34,;7.12,-.57,;5.78,-1.34,;4.45,-2.11,;4.45,-3.66,;5.78,-4.43,;7.12,-3.66,;7.12,-2.11,;5.78,-5.97,;7.12,-6.74,;8.45,-5.97,;7.12,-8.29,;8.45,-9.06,;8.45,-10.6,;9.78,-11.37,;4.66,-.24,;5.06,1.23,;3.96,2.33,;2.51,1.91,;2.11,.44,;3.21,-.66,)| Show InChI InChI=1S/C25H31N3O3/c1-3-17-26-24(30)28-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-27-23(29)21-11-7-8-12-22(21)31-2/h3-12,20H,1,13-18H2,2H3,(H,27,29)(H2,26,28,30)/t20-,25-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DiTc binding to Kv1.3 channel in human brain membranes				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50158204 (Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...) Show SMILES C[C@@H](OC(C)=O)[C@]12COCC=CC1[C@]1(C)CCC3C(O)(CCc4ccccc4C(F)(F)F)C(C)=C[C@@H](OC(C)=O)[C@]3(C)C1[C@H](OC(C)=O)[C@@H]2OC(C)=O |c:10,35| Show InChI InChI=1S/C40H51F3O10/c1-22-20-32(51-25(4)45)37(8)31(39(22,48)18-15-28-12-9-10-13-29(28)40(41,42)43)16-17-36(7)30-14-11-19-49-21-38(30,23(2)50-24(3)44)35(53-27(6)47)33(34(36)37)52-26(5)46/h9-14,20,23,30-35,48H,15-19,21H2,1-8H3/t23-,30?,31?,32-,33+,34?,35+,36+,37-,38-,39?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cells				Bioorg Med Chem Lett 15: 447-51 (2004) Article DOI: 10.1016/j.bmcl.2004.10.058 BindingDB Entry DOI: 10.7270/Q2BP0281
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50125513 (CHEMBL277598 | {4-[(2-Methoxy-benzoylamino)-methyl...) Show SMILES COc1ccccc1C(=O)NC[C@@]1(CC[C@@H](CC1)NC(=O)OCC=C)c1ccccc1 |wU:12.12,15.19,(12.7,1.28,;14.04,.51,;14.04,-1.04,;15.37,-1.81,;15.37,-3.35,;14.04,-4.12,;12.7,-3.35,;12.7,-1.81,;11.35,-1.04,;11.35,.53,;10.02,-1.81,;8.68,-1.04,;7.35,-1.81,;6.02,-2.58,;6.02,-4.12,;7.35,-4.89,;8.68,-4.12,;8.68,-2.58,;7.35,-6.44,;8.68,-7.21,;10.02,-6.44,;8.68,-8.75,;10.02,-9.52,;10.02,-11.07,;11.35,-11.84,;6.23,-.71,;6.62,.76,;5.53,1.86,;4.07,1.44,;3.68,-.03,;4.77,-1.13,)| Show InChI InChI=1S/C25H30N2O4/c1-3-17-31-24(29)27-20-13-15-25(16-14-20,19-9-5-4-6-10-19)18-26-23(28)21-11-7-8-12-22(21)30-2/h3-12,20H,1,13-18H2,2H3,(H,26,28)(H,27,29)/t20-,25-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cells				Bioorg Med Chem Lett 13: 1161-4 (2003) BindingDB Entry DOI: 10.7270/Q2W09596
					More data for this Ligand-Target Pair

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