Compile Data Set for Download or QSAR

Found 59 hits with Last Name = 'tomko' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034690 (3-{[(R)-1-((S)-6-Amino-2-tert-butoxycarbonylamino-...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H](C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C20H36N4O6/c1-20(2,3)30-19(29)23-15(8-4-5-10-21)18(28)24-12-6-7-14(13-24)17(27)22-11-9-16(25)26/h14-15H,4-13,21H2,1-3H3,(H,22,27)(H,23,29)(H,25,26)/t14-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034703 (3-{[1-(3-Piperidin-4-yl-propionyl)-piperidine-3-ca...) Show SMILES OC(=O)CCNC(=O)C1CCCN(C1)C(=O)CCC1CCNCC1 Show InChI InChI=1S/C17H29N3O4/c21-15(4-3-13-5-8-18-9-6-13)20-11-1-2-14(12-20)17(24)19-10-7-16(22)23/h13-14,18H,1-12H2,(H,19,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034701 (3-{[1-(6-Amino-hexanoyl)-piperidine-3-carbonyl]-am...) Show SMILES NCCCCCC(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C15H27N3O4/c16-8-3-1-2-6-13(19)18-10-4-5-12(11-18)15(22)17-9-7-14(20)21/h12H,1-11,16H2,(H,17,22)(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034692 (3-{[(S)-1-((S)-6-Amino-2-tert-butoxycarbonylamino-...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H](C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C20H36N4O6/c1-20(2,3)30-19(29)23-15(8-4-5-10-21)18(28)24-12-6-7-14(13-24)17(27)22-11-9-16(25)26/h14-15H,4-13,21H2,1-3H3,(H,22,27)(H,23,29)(H,25,26)/t14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034700 (3-{[1-((S)-6-Amino-2-tert-butoxycarbonylamino-hexa...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCN)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C20H36N4O6/c1-20(2,3)30-19(29)23-15(8-4-5-10-21)18(28)24-12-6-7-14(13-24)17(27)22-11-9-16(25)26/h14-15H,4-13,21H2,1-3H3,(H,22,27)(H,23,29)(H,25,26)/t14?,15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034696 ((S)-2-{[1-((S)-6-Amino-2-tert-butoxycarbonylamino-...) Show SMILES COC(=O)[C@H](CC(O)=O)NC(=O)C1CCCN(C1)C(=O)[C@H](CCCCN)NC(=O)OC(C)(C)C Show InChI InChI=1S/C22H38N4O8/c1-22(2,3)34-21(32)25-15(9-5-6-10-23)19(30)26-11-7-8-14(13-26)18(29)24-16(12-17(27)28)20(31)33-4/h14-16H,5-13,23H2,1-4H3,(H,24,29)(H,25,32)(H,27,28)/t14?,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034702 (3-{[1-((R)-2-Acetylamino-6-amino-hexanoyl)-piperid...) Show SMILES CC(=O)N[C@H](CCCCN)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C17H30N4O5/c1-12(22)20-14(6-2-3-8-18)17(26)21-10-4-5-13(11-21)16(25)19-9-7-15(23)24/h13-14H,2-11,18H2,1H3,(H,19,25)(H,20,22)(H,23,24)/t13?,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035963 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N5OS/c20-18(21,22)12-5-3-4-11(8-12)14-10-32-17(29-14)30-15(19(23,24)25)13(9-28-30)16(31)27-7-2-1-6-26/h3-5,8-10H,1-2,6-7,26H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034694 (3-{[1-((S)-2-Acetylamino-6-amino-hexanoyl)-piperid...) Show SMILES CC(=O)N[C@@H](CCCCN)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C17H30N4O5/c1-12(22)20-14(6-2-3-8-18)17(26)21-10-4-5-13(11-21)16(25)19-9-7-15(23)24/h13-14H,2-11,18H2,1H3,(H,19,25)(H,20,22)(H,23,24)/t13?,14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035955 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H23F6N5OS/c1-3-32(4-2)10-6-9-29-19(34)16-12-30-33(18(16)22(26,27)28)20-31-17(13-35-20)14-7-5-8-15(11-14)21(23,24)25/h5,7-8,11-13H,3-4,6,9-10H2,1-2H3,(H,29,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034697 (3-{[1-((R)-6-Amino-2-tert-butoxycarbonylamino-hexa...) Show SMILES CC(C)(C)OC(=O)N[C@H](CCCCN)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C20H36N4O6/c1-20(2,3)30-19(29)23-15(8-4-5-10-21)18(28)24-12-6-7-14(13-24)17(27)22-11-9-16(25)26/h14-15H,4-13,21H2,1-3H3,(H,22,27)(H,23,29)(H,25,26)/t14?,15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034685 (3-{[1-((S)-2,6-Diamino-hexanoyl)-piperidine-3-carb...) Show SMILES NCCCC[C@H](N)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C15H28N4O4/c16-7-2-1-5-12(17)15(23)19-9-3-4-11(10-19)14(22)18-8-6-13(20)21/h11-12H,1-10,16-17H2,(H,18,22)(H,20,21)/t11?,12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034704 ((S)-3-[2-((S)-2-Amino-5-guanidino-pentanoylamino)-...) Show SMILES N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CS)C(O)=O Show InChI InChI=1S/C15H27N7O7S/c16-7(2-1-3-19-15(17)18)12(26)20-5-10(23)21-8(4-11(24)25)13(27)22-9(6-30)14(28)29/h7-9,30H,1-6,16H2,(H,20,26)(H,21,23)(H,22,27)(H,24,25)(H,28,29)(H4,17,18,19)/t7-,8-,9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035961 (1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(c(Br)s2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H22BrF6N5OS/c1-3-33(4-2)10-6-9-30-19(35)15-12-31-34(17(15)22(27,28)29)20-32-16(18(23)36-20)13-7-5-8-14(11-13)21(24,25)26/h5,7-8,11-12H,3-4,6,9-10H2,1-2H3,(H,30,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035961 (1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(c(Br)s2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H22BrF6N5OS/c1-3-33(4-2)10-6-9-30-19(35)15-12-31-34(17(15)22(27,28)29)20-32-16(18(23)36-20)13-7-5-8-14(11-13)21(24,25)26/h5,7-8,11-12H,3-4,6,9-10H2,1-2H3,(H,30,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035970 (3-(8-Guanidino-octanoylamino)-N-[2-(4-methoxy-phen...) Show SMILES COc1ccc(CCNC(=O)C(CC(O)=O)NC(=O)CCCCCCCNC(N)=N)cc1 Show InChI InChI=1S/C22H35N5O5/c1-32-17-10-8-16(9-11-17)12-14-25-21(31)18(15-20(29)30)27-19(28)7-5-3-2-4-6-13-26-22(23)24/h8-11,18H,2-7,12-15H2,1H3,(H,25,31)(H,27,28)(H,29,30)(H4,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035955 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H23F6N5OS/c1-3-32(4-2)10-6-9-29-19(34)16-12-30-33(18(16)22(26,27)28)20-31-17(13-35-20)14-7-5-8-15(11-14)21(23,24)25/h5,7-8,11-13H,3-4,6,9-10H2,1-2H3,(H,29,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034689 (3-{[1-((R)-2,6-Diamino-hexanoyl)-piperidine-3-carb...) Show SMILES NCCCC[C@@H](N)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C15H28N4O4/c16-7-2-1-5-12(17)15(23)19-9-3-4-11(10-19)14(22)18-8-6-13(20)21/h11-12H,1-10,16-17H2,(H,18,22)(H,20,21)/t11?,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034698 (3-{[1-((R)-2-tert-Butoxycarbonylamino-5-guanidino-...) Show SMILES CC(C)(C)OC(=O)N[C@H](CCCNC(N)=N)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C20H36N6O6/c1-20(2,3)32-19(31)25-14(7-4-9-24-18(21)22)17(30)26-11-5-6-13(12-26)16(29)23-10-8-15(27)28/h13-14H,4-12H2,1-3H3,(H,23,29)(H,25,31)(H,27,28)(H4,21,22,24)/t13?,14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035962 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES FC(F)(F)c1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C23H23F6N5OS/c24-22(25,26)16-7-4-6-15(12-16)18-14-36-21(32-18)34-19(23(27,28)29)17(13-31-34)20(35)30-8-5-11-33-9-2-1-3-10-33/h4,6-7,12-14H,1-3,5,8-11H2,(H,30,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035960 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C18H15F6N5OS/c19-17(20,21)11-4-1-3-10(7-11)13-9-31-16(28-13)29-14(18(22,23)24)12(8-27-29)15(30)26-6-2-5-25/h1,3-4,7-9H,2,5-6,25H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035961 (1-[5-Bromo-4-(3-trifluoromethyl-phenyl)-thiazol-2-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(c(Br)s2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H22BrF6N5OS/c1-3-33(4-2)10-6-9-30-19(35)15-12-31-34(17(15)22(27,28)29)20-32-16(18(23)36-20)13-7-5-8-14(11-13)21(24,25)26/h5,7-8,11-12H,3-4,6,9-10H2,1-2H3,(H,30,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035956 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCCNCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C21H21F6N5OS/c1-2-7-28-8-4-9-29-18(33)15-11-30-32(17(15)21(25,26)27)19-31-16(12-34-19)13-5-3-6-14(10-13)20(22,23)24/h3,5-6,10-12,28H,2,4,7-9H2,1H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035960 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C18H15F6N5OS/c19-17(20,21)11-4-1-3-10(7-11)13-9-31-16(28-13)29-14(18(22,23)24)12(8-27-29)15(30)26-6-2-5-25/h1,3-4,7-9H,2,5-6,25H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035956 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCCNCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C21H21F6N5OS/c1-2-7-28-8-4-9-29-18(33)15-11-30-32(17(15)21(25,26)27)19-31-16(12-34-19)13-5-3-6-14(10-13)20(22,23)24/h3,5-6,10-12,28H,2,4,7-9H2,1H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034686 (CHEMBL409436 | HisHisLeuGlyGlyAlaLysGlnAlaGlyAspVa...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(O)=O Show InChI InChI=1S/C50H80N18O16/c1-24(2)13-33(67-48(81)34(15-29-18-55-23-60-29)66-44(77)30(52)14-28-17-54-22-59-28)45(78)58-19-37(70)56-20-38(71)61-27(6)43(76)64-31(9-7-8-12-51)47(80)65-32(10-11-36(53)69)46(79)62-26(5)42(75)57-21-39(72)63-35(16-40(73)74)49(82)68-41(25(3)4)50(83)84/h17-18,22-27,30-35,41H,7-16,19-21,51-52H2,1-6H3,(H2,53,69)(H,54,59)(H,55,60)(H,56,70)(H,57,75)(H,58,78)(H,61,71)(H,62,79)(H,63,72)(H,64,76)(H,65,80)(H,66,77)(H,67,81)(H,68,82)(H,73,74)(H,83,84)/t26-,27-,30-,31-,32-,33-,34-,35-,41-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035955 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCN(CC)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C22H23F6N5OS/c1-3-32(4-2)10-6-9-29-19(34)16-12-30-33(18(16)22(26,27)28)20-31-17(13-35-20)14-7-5-8-15(11-14)21(23,24)25/h5,7-8,11-13H,3-4,6,9-10H2,1-2H3,(H,29,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035963 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N5OS/c20-18(21,22)12-5-3-4-11(8-12)14-10-32-17(29-14)30-15(19(23,24)25)13(9-28-30)16(31)27-7-2-1-6-26/h3-5,8-10H,1-2,6-7,26H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM22360 (2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034691 (3-{[1-(6-Amino-hexanoyl)-piperidin-3-ylmethyl]-ami...) Show SMILES NCCCCCC(=O)N1CCCC(CNCCC(O)=O)C1 Show InChI InChI=1S/C15H29N3O3/c16-8-3-1-2-6-14(19)18-10-4-5-13(12-18)11-17-9-7-15(20)21/h13,17H,1-12,16H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034688 (4-{[1-((S)-6-Amino-2-tert-butoxycarbonylamino-hexa...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCN)C(=O)N1CCCC(C1)C(=O)NCCCC(O)=O Show InChI InChI=1S/C21H38N4O6/c1-21(2,3)31-20(30)24-16(9-4-5-11-22)19(29)25-13-7-8-15(14-25)18(28)23-12-6-10-17(26)27/h15-16H,4-14,22H2,1-3H3,(H,23,28)(H,24,30)(H,26,27)/t15?,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50241180 ((6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-16-hyd...) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](-[#8])=O |r| Show InChI InChI=1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035970 (3-(8-Guanidino-octanoylamino)-N-[2-(4-methoxy-phen...) Show SMILES COc1ccc(CCNC(=O)C(CC(O)=O)NC(=O)CCCCCCCNC(N)=N)cc1 Show InChI InChI=1S/C22H35N5O5/c1-32-17-10-8-16(9-11-17)12-14-25-21(31)18(15-20(29)30)27-19(28)7-5-3-2-4-6-13-26-22(23)24/h8-11,18H,2-7,12-15H2,1H3,(H,25,31)(H,27,28)(H,29,30)(H4,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035970 (3-(8-Guanidino-octanoylamino)-N-[2-(4-methoxy-phen...) Show SMILES COc1ccc(CCNC(=O)C(CC(O)=O)NC(=O)CCCCCCCNC(N)=N)cc1 Show InChI InChI=1S/C22H35N5O5/c1-32-17-10-8-16(9-11-17)12-14-25-21(31)18(15-20(29)30)27-19(28)7-5-3-2-4-6-13-26-22(23)24/h8-11,18H,2-7,12-15H2,1H3,(H,25,31)(H,27,28)(H,29,30)(H4,23,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035956 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CCCNCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C21H21F6N5OS/c1-2-7-28-8-4-9-29-18(33)15-11-30-32(17(15)21(25,26)27)19-31-16(12-34-19)13-5-3-6-14(10-13)20(22,23)24/h3,5-6,10-12,28H,2,4,7-9H2,1H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035964 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CC(C)NCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C21H21F6N5OS/c1-12(2)28-7-4-8-29-18(33)15-10-30-32(17(15)21(25,26)27)19-31-16(11-34-19)13-5-3-6-14(9-13)20(22,23)24/h3,5-6,9-12,28H,4,7-8H2,1-2H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035972 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C17H13F6N5OS/c18-16(19,20)10-3-1-2-9(6-10)12-8-30-15(27-12)28-13(17(21,22)23)11(7-26-28)14(29)25-5-4-24/h1-3,6-8H,4-5,24H2,(H,25,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of thrombin-induced platelet aggregation at 50 uM				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035962 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES FC(F)(F)c1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCN1CCCCC1 Show InChI InChI=1S/C23H23F6N5OS/c24-22(25,26)16-7-4-6-15(12-16)18-14-36-21(32-18)34-19(23(27,28)29)17(13-31-34)20(35)30-8-5-11-33-9-2-1-3-10-33/h4,6-7,12-14H,1-3,5,8-11H2,(H,30,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035960 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C18H15F6N5OS/c19-17(20,21)11-4-1-3-10(7-11)13-9-31-16(28-13)29-14(18(22,23)24)12(8-27-29)15(30)26-6-2-5-25/h1,3-4,7-9H,2,5-6,25H2,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50241180 ((6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-16-hyd...) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](-[#8])=O |r| Show InChI InChI=1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of arachidonic acid-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035953 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES CN(C)\C=N\CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C21H20F6N6OS/c1-32(2)12-28-7-4-8-29-18(34)15-10-30-33(17(15)21(25,26)27)19-31-16(11-35-19)13-5-3-6-14(9-13)20(22,23)24/h3,5-6,9-12H,4,7-8H2,1-2H3,(H,29,34)/b28-12+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50241180 ((6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-16-hyd...) Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](-[#8])=O |r| Show InChI InChI=1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of collagen-induced platelet aggregation				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035954 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NC(=N)NCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N7OS/c20-18(21,22)11-4-1-3-10(7-11)13-9-34-17(31-13)32-14(19(23,24)25)12(8-30-32)15(33)28-5-2-6-29-16(26)27/h1,3-4,7-9H,2,5-6H2,(H,28,33)(H4,26,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035963 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NCCCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H17F6N5OS/c20-18(21,22)12-5-3-4-11(8-12)14-10-32-17(29-14)30-15(19(23,24)25)13(9-28-30)16(31)27-7-2-1-6-26/h3-5,8-10H,1-2,6-7,26H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034684 (3-{[(R)-1-((S)-6-Benzyloxycarbonylamino-2-tert-but...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1CCC[C@H](C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C28H42N4O8/c1-28(2,3)40-27(38)31-22(13-7-8-15-30-26(37)39-19-20-10-5-4-6-11-20)25(36)32-17-9-12-21(18-32)24(35)29-16-14-23(33)34/h4-6,10-11,21-22H,7-9,12-19H2,1-3H3,(H,29,35)(H,30,37)(H,31,38)(H,33,34)/t21-,22+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034695 (3-{[1-((R)-2-tert-Butoxycarbonylamino-6-isopropyla...) Show SMILES CC(C)NCCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCCC(C1)C(=O)NCCC(O)=O Show InChI InChI=1S/C23H42N4O6/c1-16(2)24-12-7-6-10-18(26-22(32)33-23(3,4)5)21(31)27-14-8-9-17(15-27)20(30)25-13-11-19(28)29/h16-18,24H,6-15H2,1-5H3,(H,25,30)(H,26,32)(H,28,29)/t17?,18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035967 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NC(=N)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H16F6N6OS/c20-18(21,22)11-4-1-3-10(7-11)13-9-33-17(30-13)31-15(19(23,24)25)12(8-29-31)16(32)28-6-2-5-14(26)27/h1,3-4,7-9H,2,5-6H2,(H3,26,27)(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034705 (CHEMBL287793 | {[1-((R)-2-Acetylamino-6-amino-hexa...) Show SMILES CC(=O)N[C@H](CCCCN)C(=O)N1CCCC(C1)C(=O)NCC(O)=O Show InChI InChI=1S/C16H28N4O5/c1-11(21)19-13(6-2-3-7-17)16(25)20-8-4-5-12(10-20)15(24)18-9-14(22)23/h12-13H,2-10,17H2,1H3,(H,18,24)(H,19,21)(H,22,23)/t12?,13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of biotinylated fibrinogen binding to isolated alpha IIb beta3 integrin				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035957 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES FC(F)(F)c1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCNC1CCCCC1 Show InChI InChI=1S/C24H25F6N5OS/c25-23(26,27)16-7-4-6-15(12-16)19-14-37-22(34-19)35-20(24(28,29)30)18(13-33-35)21(36)32-11-5-10-31-17-8-2-1-3-9-17/h4,6-7,12-14,17,31H,1-3,5,8-11H2,(H,32,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50034687 (CHEMBL40646 | [3-(2-tert-Butoxycarbonylamino-6-iso...) Show SMILES CC(C)NCCCCC(NC(=O)OC(C)(C)C)C(=O)NC12CC3CC(CC(C3)(C1)NCC(O)=O)C2 |TLB:19:20:25:22.27.23,23:24:28:22.21.27,THB:21:20:25:22.27.23,21:22:20.28.34:25,23:22:28:24.34.25| Show InChI InChI=1S/C26H46N4O5/c1-17(2)27-9-7-6-8-20(29-23(34)35-24(3,4)5)22(33)30-26-13-18-10-19(14-26)12-25(11-18,16-26)28-15-21(31)32/h17-20,27-28H,6-16H2,1-5H3,(H,29,34)(H,30,33)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of fibrinogen binding to isolated integrin alphaIIb-beta3 at 50 uM.				J Med Chem 38: 1582-92 (1995) BindingDB Entry DOI: 10.7270/Q2GB233R
					More data for this Ligand-Target Pair

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