Found 159 hits with Last Name = 'vortherms' and Initial = 'ta' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372292
(CHEMBL441903)Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372290
(CHEMBL269951)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372322
(CHEMBL271898)Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | KEGG
UniProtKB/SwissProt
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| Article PubMed
| 2.70 | -48.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 6571-80 (2008)
Article DOI: 10.1021/jm8005959 BindingDB Entry DOI: 10.7270/Q24J0CD9 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM26226
((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)Show SMILES [H][C@]12CCCC[C@@]1([H])C1=C(CCc3c(nc(N)nc13)N1CCNCC1)O2 |r,t:9| Show InChI InChI=1S/C18H25N5O/c19-18-21-16-12(17(22-18)23-9-7-20-8-10-23)5-6-14-15(16)11-3-1-2-4-13(11)24-14/h11,13,20H,1-10H2,(H2,19,21,22)/t11-,13+/m1/s1 | KEGG
UniProtKB/SwissProt
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| Article PubMed
| 3.40 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 7094-8 (2008)
Article DOI: 10.1021/jm8007618 BindingDB Entry DOI: 10.7270/Q2862DS6 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372294
(CHEMBL402187)Show InChI InChI=1S/C17H22N2O/c1-13-7-6-11-19(13)12-10-16-14(2)20-17(18-16)15-8-4-3-5-9-15/h3-5,8-9,13H,6-7,10-12H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Rattus norvegicus (rat)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | KEGG
UniProtKB/SwissProt
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| Article PubMed
| 4.70 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 7094-8 (2008)
Article DOI: 10.1021/jm8007618 BindingDB Entry DOI: 10.7270/Q2862DS6 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372304
(CHEMBL257915)Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372291
(CHEMBL271661)Show InChI InChI=1S/C19H23NO/c1-2-6-18(7-3-1)16-21-19-10-8-17(9-11-19)12-15-20-13-4-5-14-20/h1-3,6-11H,4-5,12-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372303
(CHEMBL403052)Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM26226
((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)Show SMILES [H][C@]12CCCC[C@@]1([H])C1=C(CCc3c(nc(N)nc13)N1CCNCC1)O2 |r,t:9| Show InChI InChI=1S/C18H25N5O/c19-18-21-16-12(17(22-18)23-9-7-20-8-10-23)5-6-14-15(16)11-3-1-2-4-13(11)24-14/h11,13,20H,1-10H2,(H2,19,21,22)/t11-,13+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 5.80 | -47.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 7094-8 (2008)
Article DOI: 10.1021/jm8007618 BindingDB Entry DOI: 10.7270/Q2862DS6 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372290
(CHEMBL269951)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372335
(CHEMBL402872)Show InChI InChI=1S/C15H24N2/c1-13-5-4-11-17(13)12-10-14-6-8-15(9-7-14)16(2)3/h6-9,13H,4-5,10-12H2,1-3H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372292
(CHEMBL441903)Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372323
(CHEMBL404532)Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372305
(CHEMBL272141)Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372329
(CHEMBL270630)Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM21130
(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| 11.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University
Curated by PDSP Ki Database
| |
Biochemistry 44: 8643-51 (2005)
Article DOI: 10.1021/bi050490d BindingDB Entry DOI: 10.7270/Q2QN65BH |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | -45.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 6571-80 (2008)
Article DOI: 10.1021/jm8005959 BindingDB Entry DOI: 10.7270/Q24J0CD9 |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM22566
(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| 12 | -45.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 7094-8 (2008)
Article DOI: 10.1021/jm8007618 BindingDB Entry DOI: 10.7270/Q2862DS6 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372322
(CHEMBL271898)Show InChI InChI=1S/C14H21NO/c1-12-4-3-10-15(12)11-9-13-5-7-14(16-2)8-6-13/h5-8,12H,3-4,9-11H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM26226
((12S,17S)-6-(piperazin-1-yl)-11-oxa-3,5-diazatetra...)Show SMILES [H][C@]12CCCC[C@@]1([H])C1=C(CCc3c(nc(N)nc13)N1CCNCC1)O2 |r,t:9| Show InChI InChI=1S/C18H25N5O/c19-18-21-16-12(17(22-18)23-9-7-20-8-10-23)5-6-14-15(16)11-3-1-2-4-13(11)24-14/h11,13,20H,1-10H2,(H2,19,21,22)/t11-,13+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 13.5 | -44.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 7094-8 (2008)
Article DOI: 10.1021/jm8007618 BindingDB Entry DOI: 10.7270/Q2862DS6 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372296
(CHEMBL402377)Show InChI InChI=1S/C17H21N/c1-14-5-4-11-18(14)12-10-15-8-9-16-6-2-3-7-17(16)13-15/h2-3,6-9,13-14H,4-5,10-12H2,1H3/t14-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372318
(CHEMBL402220)Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372324
(CHEMBL439429)Show InChI InChI=1S/C14H21NO/c1-12-5-4-9-15(12)10-8-13-6-3-7-14(11-13)16-2/h3,6-7,11-12H,4-5,8-10H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372339
(CHEMBL255141)Show InChI InChI=1S/C10H16N2S/c1-9-3-2-7-12(9)8-5-10-4-6-11-13-10/h4,6,9H,2-3,5,7-8H2,1H3/t9-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372321
(CHEMBL272988)Show InChI InChI=1S/C15H20N2/c1-12-5-4-9-17(12)10-8-14-11-13-6-2-3-7-15(13)16-14/h2-3,6-7,11-12,16H,4-5,8-10H2,1H3/t12-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372334
(CHEMBL257235)Show InChI InChI=1S/C13H18N2O2/c1-11-3-2-9-14(11)10-8-12-4-6-13(7-5-12)15(16)17/h4-7,11H,2-3,8-10H2,1H3/t11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372331
(CHEMBL404834)Show InChI InChI=1S/C13H19NO/c1-11-5-4-9-14(11)10-8-12-6-2-3-7-13(12)15/h2-3,6-7,11,15H,4-5,8-10H2,1H3/t11-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM21130
(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)Show SMILES CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 23.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University
Curated by PDSP Ki Database
| |
Biochemistry 44: 8643-51 (2005)
Article DOI: 10.1021/bi050490d BindingDB Entry DOI: 10.7270/Q2QN65BH |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372317
(CHEMBL271237)Show InChI InChI=1S/C16H20N2O/c1-13-15(9-12-18-10-5-6-11-18)17-16(19-13)14-7-3-2-4-8-14/h2-4,7-8H,5-6,9-12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372313
(CHEMBL257911)Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372298
(CHEMBL402415)Show InChI InChI=1S/C17H22N2O/c1-13-7-6-11-19(13)12-10-16-14(2)20-17(18-16)15-8-4-3-5-9-15/h3-5,8-9,13H,6-7,10-12H2,1-2H3/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372293
(CHEMBL270410)Show InChI InChI=1S/C16H19N/c1-2-6-16-13-14(7-8-15(16)5-1)9-12-17-10-3-4-11-17/h1-2,5-8,13H,3-4,9-12H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372304
(CHEMBL257915)Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372327
(CHEMBL404912)Show InChI InChI=1S/C14H21NO/c1-12-6-5-10-15(12)11-9-13-7-3-4-8-14(13)16-2/h3-4,7-8,12H,5-6,9-11H2,1-2H3/t12-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM86548
(CAS_83729-01-5 | NSC_128563 | Salvinorin A)Show SMILES COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(CC21C)c1ccoc1 Show InChI InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Case Western Reserve University
Curated by PDSP Ki Database
| |
Biochemistry 44: 8643-51 (2005)
Article DOI: 10.1021/bi050490d BindingDB Entry DOI: 10.7270/Q2QN65BH |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372315
(CHEMBL257914)Show InChI InChI=1S/C14H21N/c1-12-5-3-7-14(11-12)8-10-15-9-4-6-13(15)2/h3,5,7,11,13H,4,6,8-10H2,1-2H3/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372340
(CHEMBL406698)Show InChI InChI=1S/C10H16N2S/c1-9-3-2-7-12(9)8-5-10-4-6-11-13-10/h4,6,9H,2-3,5,7-8H2,1H3/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372337
(CHEMBL402873)Show InChI InChI=1S/C11H17NS/c1-10-4-2-7-12(10)8-6-11-5-3-9-13-11/h3,5,9-10H,2,4,6-8H2,1H3/t10-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372310
(CHEMBL408259)Show InChI InChI=1S/C14H22N2/c1-3-13-6-7-14(15-11-13)8-10-16-9-4-5-12(16)2/h6-7,11-12H,3-5,8-10H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372302
(CHEMBL404375)Show InChI InChI=1S/C14H21NO/c1-12-6-5-10-15(12)11-9-13-7-3-4-8-14(13)16-2/h3-4,7-8,12H,5-6,9-11H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372329
(CHEMBL270630)Show InChI InChI=1S/C16H25N/c1-12-10-13(2)16(14(3)11-12)7-9-17-8-5-6-15(17)4/h10-11,15H,5-9H2,1-4H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM26229
(2-Aminopyrimidine analog., 4 | 4-[2-amino-6-(4-met...)Show InChI InChI=1S/C16H18N6/c1-21-6-8-22(9-7-21)15-10-14(19-16(18)20-15)13-4-2-12(11-17)3-5-13/h2-5,10H,6-9H2,1H3,(H2,18,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 35 | -42.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Abbott Laboratories
| Assay Description Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac... |
J Med Chem 51: 6571-80 (2008)
Article DOI: 10.1021/jm8005959 BindingDB Entry DOI: 10.7270/Q24J0CD9 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372303
(CHEMBL403052)Show InChI InChI=1S/C14H21N/c1-12-5-7-14(8-6-12)9-11-15-10-3-4-13(15)2/h5-8,13H,3-4,9-11H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372291
(CHEMBL271661)Show InChI InChI=1S/C19H23NO/c1-2-6-18(7-3-1)16-21-19-10-8-17(9-11-19)12-15-20-13-4-5-14-20/h1-3,6-11H,4-5,12-16H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372318
(CHEMBL402220)Show InChI InChI=1S/C16H22N2O/c1-12-4-3-8-18(12)9-7-14-10-13-11-15(19-2)5-6-16(13)17-14/h5-6,10-12,17H,3-4,7-9H2,1-2H3/t12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372301
(CHEMBL272307)Show InChI InChI=1S/C13H19NO/c1-15-13-6-4-12(5-7-13)8-11-14-9-2-3-10-14/h4-7H,2-3,8-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |