Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vesicular acetylcholine transporter (Torpedo californica) | BDBM50039623 ((2R,3R)-5-Amino-3-(4-phenyl-piperidin-1-yl)-1,2,3,...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from VAChT in Torpedo californica electric organ synaptic vesicles | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM50514081 (CHEMBL4471466) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasma kallikrein by Michaelis-menten analysis | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Torpedo californica) | BDBM50039613 ((2R,3R)-3-(4-Phenyl-piperidin-1-yl)-1,2,3,4-tetrah...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from VAChT in Torpedo californica electric organ synaptic vesicles | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM50514086 (CHEMBL4524734) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasma kallikrein using S2302 as substrate after 10 mins by UV/Vis photometry | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM108110 (US8598206, Table 6, 19) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM108098 (US8598206, Table 6, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasma kallikrein using S2302 as substrate | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Homo sapiens (Human)) | BDBM50366029 (CHEMBL1956465) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy Curated by ChEMBL | Assay Description Binding affinity to VAchT | Bioorg Med Chem Lett 22: 2163-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.127 BindingDB Entry DOI: 10.7270/Q2K9380F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Torpedo californica) | BDBM50095010 (CHEMBL264437) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from VAChT in Torpedo californica electric organ synaptic vesicles | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Homo sapiens (Human)) | BDBM50046952 ((3'R,4'R)-1'-(4-Fluoro-benzyl)-4-phenyl-[1,3']bipi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy Curated by ChEMBL | Assay Description Binding affinity to VAchT | Bioorg Med Chem Lett 22: 2163-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.127 BindingDB Entry DOI: 10.7270/Q2K9380F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K-dependent protein C (Homo sapiens (Human)) | BDBM50514081 (CHEMBL4471466) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of activated protein kinase C (unknown origin) | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50514082 (CHEMBL4462811) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate after 10 mins by UV/Vis photometry | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM108098 (US8598206, Table 6, 7) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM50514082 (CHEMBL4462811) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasma kallikrein using S2302 as substrate after 10 mins by UV/Vis photometry | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Torpedo californica) | BDBM50018094 ((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Binding affinity to VAChT Torpedo californica electric organ synaptic vesicles | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50514086 (CHEMBL4524734) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate after 10 mins by UV/Vis photometry | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50039613 ((2R,3R)-3-(4-Phenyl-piperidin-1-yl)-1,2,3,4-tetrah...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM108110 (US8598206, Table 6, 19) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasma kallikrein using S2302 as substrate | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM29388 (Exanta | Melagatran | US11584714, Compound 999) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of thrombin (unknown origin) | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50514081 (CHEMBL4471466) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin by Michaelis-menten analysis | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Torpedo californica) | BDBM50292907 ((+)-trans-(4-fluorophenyl)(1-(3-hydroxy-1,2,3,4-te...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from VAChT in Torpedo californica electric organ synaptic vesicles | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM108101 (US8598206, Table 6, 10) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50380629 (CHEMBL2016877) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin assessed as reduction in proteolysis activity in presence of fibrinogen after 90 mins by SDS-PAGE analysis | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50514066 (CHEMBL4589217) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasmin assessed as reduction in proteolysis activity in presence of fibrinogen after 90 mins by SDS-PAGE analysis | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50329778 ((-)-(R,R)-5-Fluoro-3-(4-phenyl-piperidin-1-yl)-1,2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat cortical membranes after 120 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50329778 ((-)-(R,R)-5-Fluoro-3-(4-phenyl-piperidin-1-yl)-1,2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50112086 (3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluor... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01635 BindingDB Entry DOI: 10.7270/Q2JM2F72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095010 (CHEMBL264437) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50329777 ((+)-(S,S)-5-Fluoro-3-(4-phenyl-piperidin-1-yl)-1,2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50095015 (CHEMBL3589727) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasma kallikrein (Homo sapiens (Human)) | BDBM108101 (US8598206, Table 6, 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human plasma kallikrein using S2302 as substrate | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095011 (CHEMBL3589731) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095024 (CHEMBL3589719) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095080 (CHEMBL3590030) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50329776 ((rac)-5-Fluoro-3-(4-phenyl-piperidin-1-yl)-1,2,3,4...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095068 (CHEMBL3589872) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50095014 (CHEMBL3589728) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50329776 ((rac)-5-Fluoro-3-(4-phenyl-piperidin-1-yl)-1,2,3,4...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat cortical membranes after 120 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50329775 ((2R,3R)-5-Iodo-3-(4-phenyl-piperidin-1-yl)-1,2,3,4...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095057 (CHEMBL3589714) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095071 (CHEMBL3589869) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095059 (CHEMBL3589712) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50095010 (CHEMBL264437) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XI (Homo sapiens (Human)) | BDBM50514081 (CHEMBL4471466) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human factor 11a | J Med Chem 63: 1445-1472 (2020) Article DOI: 10.1021/acs.jmedchem.9b01060 BindingDB Entry DOI: 10.7270/Q2VQ361P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50095011 (CHEMBL3589731) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50329773 ((-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidi...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in rat PC12 cells after 60 mins | Bioorg Med Chem 18: 7659-67 (2010) Article DOI: 10.1016/j.bmc.2010.08.028 BindingDB Entry DOI: 10.7270/Q2PK0GCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095075 (CHEMBL3589865) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50329773 ((-)-(2R,3R)-5-(2-fluoroethoxy)-3-(4-phenylpiperidi...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50018094 ((1R,2R)-2-(4-Phenyl-piperidin-1-yl)-cyclohexanol |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50095056 (CHEMBL3589715) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation countin... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vesicular acetylcholine transporter (Rattus norvegicus) | BDBM50095013 (CHEMBL3589729) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmaceutical Cancer Research Curated by ChEMBL | Assay Description Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competit... | Eur J Med Chem 100: 50-67 (2015) Article DOI: 10.1016/j.ejmech.2015.05.033 BindingDB Entry DOI: 10.7270/Q28C9XZ1 | |||||||||||
More data for this Ligand-Target Pair |
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