BindingDB PrimarySearch

Found 40 hits with Last Name = 'wisastra' and Initial = 'r'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean))	BDBM50401193 (CHEMBL1934604) Show SMILES CCCCCCCc1ccc(CCc2cc(O)cc(O)c2C(O)=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of soyabean lipoxygenase-1 assessed as inhibition constant for enzyme-inhibitor complex by Lineweaver-Burk plot				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean))	BDBM50401193 (CHEMBL1934604) Show SMILES CCCCCCCc1ccc(CCc2cc(O)cc(O)c2C(O)=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of soyabean lipoxygenase-1 assessed as inhibition constant for enzyme-substrate-inhibitor complex by Lineweaver-Burk plot				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50444319 (CHEMBL3094153) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity to human 5-LOX using linoleic acid as substrate				Bioorg Med Chem 21: 7763-78 (2013) Article DOI: 10.1016/j.bmc.2013.10.015 BindingDB Entry DOI: 10.7270/Q2HD7X3K
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50444319 (CHEMBL3094153) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Binding affinity to human 5-LOX-linoleic acid complex				Bioorg Med Chem 21: 7763-78 (2013) Article DOI: 10.1016/j.bmc.2013.10.015 BindingDB Entry DOI: 10.7270/Q2HD7X3K
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50035507 (CHEMBL3355722) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP12 catalytic domain Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50035507 (CHEMBL3355722) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50035507 (CHEMBL3355722) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50035475 (CHEMBL3355723) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50035507 (CHEMBL3355722) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50035475 (CHEMBL3355723) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50035475 (CHEMBL3355723) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage metalloelastase (Homo sapiens (Human))	BDBM50035475 (CHEMBL3355723) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP12 catalytic domain Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea \|...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of 5-LOX				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50035472 (CHEMBL3355724) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP2 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247839 (CHEMBL447612 \| methyl 3-(5-chloro-3-oxoisothiazol-...) Show SMILES COC(=O)CCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247843 (CHEMBL510872 \| Ethyl 3-(5-chloro-3-oxoisothiazol-2...) Show SMILES CCOC(=O)CCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50035472 (CHEMBL3355724) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247840 (CHEMBL489116 \| Methyl 4-(5-chloro-3-oxoisothiazol-...) Show SMILES COC(=O)CCCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247844 (5-Chloro-2-(3-chloro-4-fluorophenyl)isothiazol-3(2...) Show SMILES Fc1ccc(cc1Cl)-n1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247845 (Benzyl [2-(5-chloro-3-oxoisothiazol-2(3H)-yl)ethyl...) Show SMILES Clc1cc(=O)n(CCNC(=O)OCc2ccccc2)s1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247841 (CHEMBL443133 \| Methyl 4-(5-chloro-3-oxoisothiazol-...) Show SMILES COC(=O)CCCCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247837 (5-Chloro-2-pentylisothiazol-3(2H)-one \| CHEMBL4891...) Show SMILES CCCCCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247838 (CHEMBL466866 \| Methyl 2-(5-chloro-3-oxoisothiazol-...) Show SMILES COC(=O)Cn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247820 (5-Chloro-2-ethylisothiazol-3(2H)-one \| CHEMBL46147...) Show SMILES CCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247842 (CHEMBL442599 \| Methyl 6-(5-chloro-3-oxoisothiazol-...) Show SMILES COC(=O)CCCCCn1sc(Cl)cc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-17 (Homo sapiens (Human))	BDBM50035472 (CHEMBL3355724) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Medical Center Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 using Mca-PLAQAV-Dpa-RSSSR-NH2				Bioorg Med Chem 23: 192-202 (2014) Article DOI: 10.1016/j.bmc.2014.11.013 BindingDB Entry DOI: 10.7270/Q26Q1ZVW
University Medical Center Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247868 (2-(3-Chloro-4-fluorophenyl)isothiazol-3(2H)-one \| ...) Show SMILES Fc1ccc(cc1Cl)-n1sccc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247871 (CHEMBL521965 \| Methyl 3-[4-{[(benzyloxy)carbonyl]a...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247869 (CHEMBL509992 \| methyl 3-(5-chloro-1-oxido-3-oxoiso...) Show SMILES COC(=O)CCn1c(=O)cc(Cl)s1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247867 (CHEMBL500338 \| methyl 6-(3-oxoisothiazol-2(3H)-yl)...) Show SMILES COC(=O)CCCCCn1sccc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247866 (CHEMBL491669 \| Methyl 4-(3-oxoisothiazol-2(3H)-yl)...) Show SMILES COC(=O)CCCn1sccc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247865 (CHEMBL450644 \| Methyl 3-(3-oxoisothiazol-2(3H)-yl)...) Show SMILES COC(=O)CCn1sccc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247864 (2-pentylisothiazol-3(2H)-one \| CHEMBL491668) Show SMILES CCCCCn1sccc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247870 (CHEMBL491670 \| Methyl 3-[(5-chloroisothiazol-3-yl)...) Show SMILES COC(=O)CCNc1cc(Cl)sn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50247846 (2-Ethylisothiazol-3(2H)-one \| CHEMBL490685) Show SMILES CCn1sccc1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human recombinant HAT PCAF				Bioorg Med Chem 17: 460-6 (2009) Article DOI: 10.1016/j.bmc.2008.12.008 BindingDB Entry DOI: 10.7270/Q2BC3ZDM
University of Groningen Curated by ChEMBL					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean))	BDBM50401193 (CHEMBL1934604) Show SMILES CCCCCCCc1ccc(CCc2cc(O)cc(O)c2C(O)=O)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Probable linoleate 9S-lipoxygenase 5 (Solanum tuberosum)	BDBM50240436 (2-Hydroxy-6-pentadecyl-benzoic acid \| 2-hydroxy-6-...) Show SMILES CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of potato 5-lipoxygenase assessed as residual activity preincubated for 10 mins measured by real-time spectrophotometric analysis				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean))	BDBM50240436 (2-Hydroxy-6-pentadecyl-benzoic acid \| 2-hydroxy-6-...) Show SMILES CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean))	BDBM50401192 (CHEMBL418973) Show SMILES CCCCCCCCCCCCCCOc1cccc(O)c1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean))	BDBM50401191 (CHEMBL2206368) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Groningen Research Institute of Pharmacy Curated by ChEMBL					Assay Description Inhibition of soyabean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophot...				Bioorg Med Chem 20: 5027-32 (2012) Article DOI: 10.1016/j.bmc.2012.06.019 BindingDB Entry DOI: 10.7270/Q20R9QJG
Groningen Research Institute of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair