Compile Data Set for Download or QSAR

Found 110 hits with Last Name = 'wu' and Initial = 'wt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330546 (4-Furan-6-methyl-N-(4-methoxyphenyl)-4,7-dihydro-2...) Show SMILES COc1ccc(NC(=O)C2C(c3ccco3)c3cn[nH]c3N=C2C)cc1 |c:23| Show InChI InChI=1S/C19H18N4O3/c1-11-16(19(24)22-12-5-7-13(25-2)8-6-12)17(15-4-3-9-26-15)14-10-20-23-18(14)21-11/h3-10,16-17H,1-2H3,(H,20,23)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330547 (4-Thiophene-6-methyl-N-(4-methoxyphenyl)-4,7-dihyd...) Show SMILES COc1ccc(NC(=O)C2C(c3cccs3)c3cn[nH]c3N=C2C)cc1 |c:23| Show InChI InChI=1S/C19H18N4O2S/c1-11-16(19(24)22-12-5-7-13(25-2)8-6-12)17(15-4-3-9-26-15)14-10-20-23-18(14)21-11/h3-10,16-17H,1-2H3,(H,20,23)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321230 ((+/-)-6-Chloro-1-(3-hydroxyphenyl)-2-(2-aminoethyl...) Show SMILES NCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 Show InChI InChI=1S/C19H20ClN3O/c20-13-4-5-17-16(11-13)15-6-8-23(9-7-21)19(18(15)22-17)12-2-1-3-14(24)10-12/h1-5,10-11,19,22,24H,6-9,21H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351284 (CHEMBL1818768) Show SMILES Oc1ccc(cc1)N1C(Cc2ccccc2)Nc2ccc(cc2C1=O)N1CCCCC1 Show InChI InChI=1S/C26H27N3O2/c30-22-12-9-20(10-13-22)29-25(17-19-7-3-1-4-8-19)27-24-14-11-21(18-23(24)26(29)31)28-15-5-2-6-16-28/h1,3-4,7-14,18,25,27,30H,2,5-6,15-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351271 (CHEMBL1818755) Show SMILES Oc1cccc(c1)-c1nc2ccc(cc2c(O)c1Cc1ccccc1)N1CCCCC1 Show InChI InChI=1S/C27H26N2O2/c30-22-11-7-10-20(17-22)26-24(16-19-8-3-1-4-9-19)27(31)23-18-21(12-13-25(23)28-26)29-14-5-2-6-15-29/h1,3-4,7-13,17-18,30H,2,5-6,14-16H2,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351274 (CHEMBL1818758) Show SMILES Oc1cccc(c1)-c1nc2ccc(cc2c(O)c1Cc1ccccc1)N1CCOCC1 Show InChI InChI=1S/C26H24N2O3/c29-21-8-4-7-19(16-21)25-23(15-18-5-2-1-3-6-18)26(30)22-17-20(9-10-24(22)27-25)28-11-13-31-14-12-28/h1-10,16-17,29H,11-15H2,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351290 (CHEMBL1818774) Show SMILES Oc1ccc(cc1)N1C(Cc2ccccc2)Nc2ccc(cc2C1=O)N1CCCC1 Show InChI InChI=1S/C25H25N3O2/c29-21-11-8-19(9-12-21)28-24(16-18-6-2-1-3-7-18)26-23-13-10-20(17-22(23)25(28)30)27-14-4-5-15-27/h1-3,6-13,17,24,26,29H,4-5,14-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50198311 ((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...) Show SMILES CC[C@@H](N(CCCN(C)C)C(=O)c1ccc(Br)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C30H32BrClN4O2/c1-4-27(35(18-8-17-34(2)3)29(37)22-11-13-23(31)14-12-22)28-33-26-19-24(32)15-16-25(26)30(38)36(28)20-21-9-6-5-7-10-21/h5-7,9-16,19,27H,4,8,17-18,20H2,1-3H3/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351283 (CHEMBL1818767) Show SMILES Oc1cccc(c1)N1C(Cc2ccccc2)Nc2ccc(cc2C1=O)N1CCCCC1 Show InChI InChI=1S/C26H27N3O2/c30-22-11-7-10-21(17-22)29-25(16-19-8-3-1-4-9-19)27-24-13-12-20(18-23(24)26(29)31)28-14-5-2-6-15-28/h1,3-4,7-13,17-18,25,27,30H,2,5-6,14-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321241 ((+/-)-1-(3-Hydroxyphenyl)-2-(beta-aminopropionyl)-...) Show SMILES NCCC(=O)N1CCc2c([nH]c3c(Cl)cccc23)C1c1cccc(O)c1 Show InChI InChI=1S/C20H20ClN3O2/c21-16-6-2-5-14-15-8-10-24(17(26)7-9-22)20(19(15)23-18(14)16)12-3-1-4-13(25)11-12/h1-6,11,20,23,25H,7-10,22H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351272 (CHEMBL1818756) Show SMILES Oc1ccc(cc1)-c1nc2ccc(cc2c(O)c1Cc1ccccc1)N1CCCCC1 Show InChI InChI=1S/C27H26N2O2/c30-22-12-9-20(10-13-22)26-24(17-19-7-3-1-4-8-19)27(31)23-18-21(11-14-25(23)28-26)29-15-5-2-6-16-29/h1,3-4,7-14,18,30H,2,5-6,15-17H2,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321222 ((+/-)-6-Chloro-1-(indol-3-yl)-2-(beta-aminopropion...) Show SMILES NCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 Show InChI InChI=1S/C22H21ClN4O/c23-13-5-6-19-16(11-13)15-8-10-27(20(28)7-9-24)22(21(15)26-19)17-12-25-18-4-2-1-3-14(17)18/h1-6,11-12,22,25-26H,7-10,24H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50198311 ((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...) Show SMILES CC[C@@H](N(CCCN(C)C)C(=O)c1ccc(Br)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C30H32BrClN4O2/c1-4-27(35(18-8-17-34(2)3)29(37)22-11-13-23(31)14-12-22)28-33-26-19-24(32)15-16-25(26)30(38)36(28)20-21-9-6-5-7-10-21/h5-7,9-16,19,27H,4,8,17-18,20H2,1-3H3/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351289 (CHEMBL1818773) Show SMILES Oc1cccc(c1)N1C(Cc2ccccc2)Nc2ccc(cc2C1=O)N1CCCC1 Show InChI InChI=1S/C25H25N3O2/c29-21-10-6-9-20(16-21)28-24(15-18-7-2-1-3-8-18)26-23-12-11-19(17-22(23)25(28)30)27-13-4-5-14-27/h1-3,6-12,16-17,24,26,29H,4-5,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321239 ((+/-)-1-(3-Hydroxyphenyl)-2-(p-aminobenzoyl)-6-met...) Show SMILES Cc1ccc2[nH]c3C(N(CCc3c2c1)C(=O)c1ccc(N)cc1)c1cccc(O)c1 Show InChI InChI=1S/C25H23N3O2/c1-15-5-10-22-21(13-15)20-11-12-28(25(30)16-6-8-18(26)9-7-16)24(23(20)27-22)17-3-2-4-19(29)14-17/h2-10,13-14,24,27,29H,11-12,26H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321227 ((+/-)-6-Methyl-1-(indol-3-yl)-2-acetyl-1,2,3,4-tet...) Show SMILES CC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 Show InChI InChI=1S/C22H21N3O/c1-13-7-8-20-17(11-13)16-9-10-25(14(2)26)22(21(16)24-20)18-12-23-19-6-4-3-5-15(18)19/h3-8,11-12,22-24H,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351259 (CHEMBL1818674) Show SMILES CN1CCN(CC1)c1ccc2nc(c(C)c(O)c2c1)-c1ccccc1 Show InChI InChI=1S/C21H23N3O/c1-15-20(16-6-4-3-5-7-16)22-19-9-8-17(14-18(19)21(15)25)24-12-10-23(2)11-13-24/h3-9,14H,10-13H2,1-2H3,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50198311 ((R)-N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquina...) Show SMILES CC[C@@H](N(CCCN(C)C)C(=O)c1ccc(Br)cc1)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C30H32BrClN4O2/c1-4-27(35(18-8-17-34(2)3)29(37)22-11-13-23(31)14-12-22)28-33-26-19-24(32)15-16-25(26)30(38)36(28)20-21-9-6-5-7-10-21/h5-7,9-16,19,27H,4,8,17-18,20H2,1-3H3/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321243 ((+/-)-1-(3-Hydroxyphenyl)-3-carboxy-1,2,3,4-tetrah...) Show SMILES NCCNC(=O)C1Cc2c([nH]c3ccccc23)C(N1)c1cccc(O)c1 Show InChI InChI=1S/C20H22N4O2/c21-8-9-22-20(26)17-11-15-14-6-1-2-7-16(14)23-19(15)18(24-17)12-4-3-5-13(25)10-12/h1-7,10,17-18,23-25H,8-9,11,21H2,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351288 (CHEMBL1818772) Show SMILES O=C1N(C(Cc2ccccc2)Nc2ccc(cc12)N1CCCC1)c1ccccc1 Show InChI InChI=1S/C25H25N3O/c29-25-22-18-21(27-15-7-8-16-27)13-14-23(22)26-24(17-19-9-3-1-4-10-19)28(25)20-11-5-2-6-12-20/h1-6,9-14,18,24,26H,7-8,15-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321249 ((+/-)-Ethyl 1-(3-hydroxyphenyl)-2-propionyl-1,2,3,...) Show SMILES CCOC(=O)C1Cc2c([nH]c3ccccc23)C(N1C(=O)CC)c1cccc(O)c1 Show InChI InChI=1S/C23H24N2O4/c1-3-20(27)25-19(23(28)29-4-2)13-17-16-10-5-6-11-18(16)24-21(17)22(25)14-8-7-9-15(26)12-14/h5-12,19,22,24,26H,3-4,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321240 ((+/-)-1-(3-Hydroxyphenyl)-2-(p-aminobenzoyl)-6-chl...) Show SMILES Nc1ccc(cc1)C(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 Show InChI InChI=1S/C24H20ClN3O2/c25-16-6-9-21-20(13-16)19-10-11-28(24(30)14-4-7-17(26)8-5-14)23(22(19)27-21)15-2-1-3-18(29)12-15/h1-9,12-13,23,27,29H,10-11,26H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321232 ((+/-)-6-Methyl-1-(3-hydroxyphenyl)-2-(3-aminopropy...) Show SMILES Cc1ccc2[nH]c3C(N(CCCN)CCc3c2c1)c1cccc(O)c1 Show InChI InChI=1S/C21H25N3O/c1-14-6-7-19-18(12-14)17-8-11-24(10-3-9-22)21(20(17)23-19)15-4-2-5-16(25)13-15/h2,4-7,12-13,21,23,25H,3,8-11,22H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351282 (CHEMBL1818766) Show SMILES O=C1N(C(Cc2ccccc2)Nc2ccc(cc12)N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C26H27N3O/c30-26-23-19-22(28-16-8-3-9-17-28)14-15-24(23)27-25(18-20-10-4-1-5-11-20)29(26)21-12-6-2-7-13-21/h1-2,4-7,10-15,19,25,27H,3,8-9,16-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321246 ((+/-)-1-(3-Hydroxyphenyl)-2-propionyl-1,2,3,4-tetr...) Show SMILES CCC(=O)N1C(Cc2c([nH]c3ccccc23)C1c1cccc(O)c1)C(O)=O Show InChI InChI=1S/C21H20N2O4/c1-2-18(25)23-17(21(26)27)11-15-14-8-3-4-9-16(14)22-19(15)20(23)12-6-5-7-13(24)10-12/h3-10,17,20,22,24H,2,11H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330548 (4-Phenyl-6-methyl-N-(4-fluorophenyl)-4,7-dihydro-2...) Show SMILES CC1=Nc2[nH]ncc2C(C1C(=O)Nc1ccc(F)cc1)c1ccccc1 |t:1| Show InChI InChI=1S/C20H17FN4O/c1-12-17(20(26)24-15-9-7-14(21)8-10-15)18(13-5-3-2-4-6-13)16-11-22-25-19(16)23-12/h2-11,17-18H,1H3,(H,22,25)(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351270 (CHEMBL1818754) Show SMILES Oc1c(Cc2ccccc2)c(nc2ccc(cc12)N1CCCCC1)-c1ccccc1 Show InChI InChI=1S/C27H26N2O/c30-27-23-19-22(29-16-8-3-9-17-29)14-15-25(23)28-26(21-12-6-2-7-13-21)24(27)18-20-10-4-1-5-11-20/h1-2,4-7,10-15,19H,3,8-9,16-18H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351281 (CHEMBL1818765) Show SMILES CC1Nc2ccc(cc2C(=O)N1c1ccc(O)cc1)N1CCCC1 Show InChI InChI=1S/C19H21N3O2/c1-13-20-18-9-6-15(21-10-2-3-11-21)12-17(18)19(24)22(13)14-4-7-16(23)8-5-14/h4-9,12-13,20,23H,2-3,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351277 (CHEMBL1818761) Show SMILES CC1Nc2ccc(cc2C(=O)N1c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C19H21N3O2/c1-14-20-18-8-7-16(21-9-11-24-12-10-21)13-17(18)19(23)22(14)15-5-3-2-4-6-15/h2-8,13-14,20H,9-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321223 ((+/-)-6-Chloro-1-(indol-3-yl)-2-isobutyryl-1,2,3,4...) Show SMILES CCCC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H22ClN3O/c1-2-5-21(28)27-11-10-16-17-12-14(24)8-9-20(17)26-22(16)23(27)18-13-25-19-7-4-3-6-15(18)19/h3-4,6-9,12-13,23,25-26H,2,5,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321237 ((+/-)-6-Chloro-1-(3-hydroxyphenyl)-2-propyl-1,2,3,...) Show SMILES CCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 Show InChI InChI=1S/C20H21ClN2O/c1-2-9-23-10-8-16-17-12-14(21)6-7-18(17)22-19(16)20(23)13-4-3-5-15(24)11-13/h3-7,11-12,20,22,24H,2,8-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351279 (CHEMBL1818763) Show SMILES CC1Nc2ccc(cc2C(=O)N1c1ccccc1)N1CCCC1 Show InChI InChI=1S/C19H21N3O/c1-14-20-18-10-9-16(21-11-5-6-12-21)13-17(18)19(23)22(14)15-7-3-2-4-8-15/h2-4,7-10,13-14,20H,5-6,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330549 (4-Phenyl-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-...) Show SMILES CC1=Nc2[nH]ncc2C(C1C(=O)Nc1ccc(F)c(Cl)c1)c1ccccc1 |t:1| Show InChI InChI=1S/C20H16ClFN4O/c1-11-17(20(27)25-13-7-8-16(22)15(21)9-13)18(12-5-3-2-4-6-12)14-10-23-26-19(14)24-11/h2-10,17-18H,1H3,(H,23,26)(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351280 (CHEMBL1818764) Show SMILES CC1Nc2ccc(cc2C(=O)N1c1cccc(O)c1)N1CCCC1 Show InChI InChI=1S/C19H21N3O2/c1-13-20-18-8-7-14(21-9-2-3-10-21)12-17(18)19(24)22(13)15-5-4-6-16(23)11-15/h4-8,11-13,20,23H,2-3,9-10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330550 (CHEMBL1277474 | N-(4-chlorophenyl)-2,7,7-trimethyl...) Show SMILES CC1=C(C(C2C(=O)CC(C)(C)CC2=N1)c1ccccc1)C(=O)Nc1ccc(Cl)cc1 |c:13,t:1| Show InChI InChI=1S/C25H25ClN2O2/c1-15-21(24(30)28-18-11-9-17(26)10-12-18)22(16-7-5-4-6-8-16)23-19(27-15)13-25(2,3)14-20(23)29/h4-12,22-23H,13-14H2,1-3H3,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330551 (4-Phenyl-6-methyl-N-(4-nitrophenyl)-4,7-dihydro-2H...) Show SMILES CC1=Nc2[nH]ncc2C(C1C(=O)Nc1ccc(cc1)[N+]([O-])=O)c1ccccc1 |t:1| Show InChI InChI=1S/C20H17N5O3/c1-12-17(20(26)23-14-7-9-15(10-8-14)25(27)28)18(13-5-3-2-4-6-13)16-11-21-24-19(16)22-12/h2-11,17-18H,1H3,(H,21,24)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321229 ((+/-)-6-Chloro-1-(3-hydroxyphenyl)-2-(3-aminopropy...) Show SMILES NCCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 Show InChI InChI=1S/C20H22ClN3O/c21-14-5-6-18-17(12-14)16-7-10-24(9-2-8-22)20(19(16)23-18)13-3-1-4-15(25)11-13/h1,3-6,11-12,20,23,25H,2,7-10,22H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	204	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321226 ((+/-)-6-Methyl-1-(indol-3-yl)-2-butyryl-1,2,3,4-te...) Show SMILES CC(C)C(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 Show InChI InChI=1S/C24H25N3O/c1-14(2)24(28)27-11-10-17-18-12-15(3)8-9-21(18)26-22(17)23(27)19-13-25-20-7-5-4-6-16(19)20/h4-9,12-14,23,25-26H,10-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321248 ((+/-)-Ethyl 1-(3-hydroxyphenyl)-2-butyryl-1,2,3,4-...) Show SMILES CCCC(=O)N1C(Cc2c([nH]c3ccccc23)C1c1cccc(O)c1)C(=O)OCC Show InChI InChI=1S/C24H26N2O4/c1-3-8-21(28)26-20(24(29)30-4-2)14-18-17-11-5-6-12-19(17)25-22(18)23(26)15-9-7-10-16(27)13-15/h5-7,9-13,20,23,25,27H,3-4,8,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351263 (CHEMBL1818747) Show SMILES Cc1c(O)c2cc(ccc2nc1-c1cccc(O)c1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O2/c1-14-20(15-6-5-7-17(24)12-15)22-19-9-8-16(13-18(19)21(14)25)23-10-3-2-4-11-23/h5-9,12-13,24H,2-4,10-11H2,1H3,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	232	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321233 ((+/-)-6-Methyl-1-(3-hydroxyphenyl)-2-(2-aminoethyl...) Show SMILES Cc1ccc2[nH]c3C(N(CCN)CCc3c2c1)c1cccc(O)c1 Show InChI InChI=1S/C20H23N3O/c1-13-5-6-18-17(11-13)16-7-9-23(10-8-21)20(19(16)22-18)14-3-2-4-15(24)12-14/h2-6,11-12,20,22,24H,7-10,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321244 ((+/-)-1-(3-Hydroxyphenyl)-3-carboxy-1,2,3,4-tetrah...) Show SMILES OCCNC(=O)C1Cc2c([nH]c3ccccc23)C(N1)c1cccc(O)c1 Show InChI InChI=1S/C20H21N3O3/c24-9-8-21-20(26)17-11-15-14-6-1-2-7-16(14)22-19(15)18(23-17)12-4-3-5-13(25)10-12/h1-7,10,17-18,22-25H,8-9,11H2,(H,21,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330552 (4-Thiophene-6-methyl-N-(4-trifluoromethylphenyl)-4...) Show SMILES CC1=Nc2[nH]ncc2C(C1C(=O)Nc1ccc(cc1)C(F)(F)F)c1cccs1 |t:1| Show InChI InChI=1S/C19H15F3N4OS/c1-10-15(18(27)25-12-6-4-11(5-7-12)19(20,21)22)16(14-3-2-8-28-14)13-9-23-26-17(13)24-10/h2-9,15-16H,1H3,(H,23,26)(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351260 (CHEMBL1818675) Show SMILES CN1CCN(CC1)c1ccc2nc(c(C)c(O)c2c1)-c1cccc(O)c1 Show InChI InChI=1S/C21H23N3O2/c1-14-20(15-4-3-5-17(25)12-15)22-19-7-6-16(13-18(19)21(14)26)24-10-8-23(2)9-11-24/h3-7,12-13,25H,8-11H2,1-2H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321225 ((+/-)-6-Chloro-1-(indol-3-yl)-2-acetyl-1,2,3,4-tet...) Show SMILES CC(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1c[nH]c2ccccc12 Show InChI InChI=1S/C21H18ClN3O/c1-12(26)25-9-8-15-16-10-13(22)6-7-19(16)24-20(15)21(25)17-11-23-18-5-3-2-4-14(17)18/h2-7,10-11,21,23-24H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	337	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321228 ((+/-)-6-Chloro-1-(3-hydroxyphenyl)-2-(3-aminobutyl...) Show SMILES NCCCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 Show InChI InChI=1S/C21H24ClN3O/c22-15-6-7-19-18(13-15)17-8-11-25(10-2-1-9-23)21(20(17)24-19)14-4-3-5-16(26)12-14/h3-7,12-13,21,24,26H,1-2,8-11,23H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50351262 (CHEMBL1818677) Show SMILES Cc1c(O)c2cc(ccc2nc1-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C21H22N2O/c1-15-20(16-8-4-2-5-9-16)22-19-11-10-17(14-18(19)21(15)24)23-12-6-3-7-13-23/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human ATPase activity KSP expressed in Escherichia coli after 30 mins by spectrophotometric analysis				Bioorg Med Chem 19: 5612-27 (2011) Article DOI: 10.1016/j.bmc.2011.07.029 BindingDB Entry DOI: 10.7270/Q2B858HD
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50321247 ((+/-)-Ethyl 1-(3-hydroxyphenyl)-2-isobutyryl-1,2,3...) Show SMILES CCOC(=O)C1Cc2c([nH]c3ccccc23)C(N1C(=O)C(C)C)c1cccc(O)c1 Show InChI InChI=1S/C24H26N2O4/c1-4-30-24(29)20-13-18-17-10-5-6-11-19(17)25-21(18)22(26(20)23(28)14(2)3)15-8-7-9-16(27)12-15/h5-12,14,20,22,25,27H,4,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Eg5 expressed in Escherichia coli assessed as microtubule-activated ATPase activity by spectrophotometry				Bioorg Med Chem 18: 4167-77 (2010) Article DOI: 10.1016/j.bmc.2010.05.024 BindingDB Entry DOI: 10.7270/Q2BK1CJP
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330554 (4-Furan-6-methyl-N-(3-chloro-4-fluorophenyl)-4,7-d...) Show SMILES CC1=Nc2[nH]ncc2C(C1C(=O)Nc1ccc(F)c(Cl)c1)c1ccco1 |t:1| Show InChI InChI=1S/C18H14ClFN4O2/c1-9-15(18(25)23-10-4-5-13(20)12(19)7-10)16(14-3-2-6-26-14)11-8-21-24-17(11)22-9/h2-8,15-16H,1H3,(H,21,24)(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50330553 (4-Phenyl-6-methyl-N-(4-trifluoromethylphenyl)-4,7-...) Show SMILES CC1=Nc2[nH]ncc2C(C1C(=O)Nc1ccc(cc1)C(F)(F)F)c1ccccc1 |t:1| Show InChI InChI=1S/C21H17F3N4O/c1-12-17(20(29)27-15-9-7-14(8-10-15)21(22,23)24)18(13-5-3-2-4-6-13)16-11-25-28-19(16)26-12/h2-11,17-18H,1H3,(H,25,28)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human full-length Eg5 ATPase activity expressed in Escherichia coli assessed as release of inorganic phosphate after 30 mins				Bioorg Med Chem 18: 8035-43 (2010) Article DOI: 10.1016/j.bmc.2010.09.020 BindingDB Entry DOI: 10.7270/Q2BZ668Q
					More data for this Ligand-Target Pair

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